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Perucca, S., Palma, A. D., Piccaluga, P. P., Gemelli, C., Zoratti, E., Bassi, G., Giacopuzzi, E., Lojacono, A., Borsani, G., Tagliafico, E., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0172430 · Cited by 41 · see citing works

Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly

Silver, J. T., Wirtz-Peitz, F., Simões, S., Pellikka, M., Yan, D., Binari, R., Nishimura, T., Li, Y., Harris, T., Perrimon, N., et al. (2019) · Journal of Cell Biology · doi:10.1083/jcb.201807106 · Cited by 32 · see citing works

RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1

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Small-Molecule Inhibitor of 8-Oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during Pseudomonas aeruginosa Infection

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Ginkgo biloba extract enhances chemotherapy sensitivity and reverses chemoresistance through suppression of the KSR1-mediated ERK1/2 pathway in gastric cancer cells

Liu, S., Xu, C., Qin, M., Tan, L., ZHUGE, C.-F., MAO, Y.-B., Lai, M., & HUANG, J.-A. (2015) · Oncology Reports · doi:10.3892/or.2015.3923 · Cited by 37 · see citing works

Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activation

Ye, Y., Jiao, H., Wang, S., Xiao, Z., Zhang, D., Qiu, J., Zhang, L., Zhao, Y., Li, T., Li-Liang, et al. (2018) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-018-0958-1 · Cited by 31 · see citing works

PPP2R5A: A multirole protein phosphatase subunit in regulating cancer development

Mao, Z., Liu, C., Lin, X., Sun, B., & Su, C. (2018) · Cancer Letters · doi:10.1016/j.canlet.2017.11.024 · Cited by 30 · see citing works

ARHGEF2/EDN1 pathway participates in ER stress-related drug resistance of hepatocellular carcinoma by promoting angiogenesis and malignant proliferation

Zhu, Y., Liu, W., Wang, Z., Wang, Y., Tan, C., Pan, Z., Wang, A., Liu, J., & Sun, G. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05099-8 · Cited by 28 · see citing works

Growth factor–dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools

Brüggemann, Y., Karajannis, L. S., Stanoev, A., Stallaert, W., & Bastiaens, P. I. H. (2021) · Science Signaling · doi:10.1126/scisignal.abd9943 · Cited by 27 · see citing works

Dynamic Regulation of Expression of KRAS and Its Effectors Determines the Ability to Initiate Tumorigenesis in Pancreatic Acinar Cells

Assi, M., Achouri, Y., Loriot, A. E., Dauguet, N., Dahou, H., Baldan, J., Libert, M., Fain, J. S., Guerra, C. E., Bouwens, L., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-2976 · Cited by 25 · see citing works

Autophagy suppresses cell migration by degrading GEF-H1, a RhoA GEF

Yoshida, T., Tsujioka, M., Honda, S., Tanaka, M., & Shimizu, S. (2016) · Oncotarget · doi:10.18632/oncotarget.8883 · Cited by 26 · see citing works

MASTL promotes cell contractility and motility through kinase-independent signaling

Taskinen, M. E., Närvä, E., Conway, J. R. W., Hinojosa, L. S., Lilla, S., Mai, A., Franceschi, N. D., Elo, L. L., Grosse, R., Zanivan, S. R., et al. (2020) · The Journal of Cell Biology · doi:10.1083/jcb.201906204 · Cited by 26 · see citing works

An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer

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A RHGEF 19 interacts with BRAF to activate MAPK signaling during the tumorigenesis of non‐small cell lung cancer

Li, Y., Ye, Z., Chen, S., Pan, Z., Zhou, Q., Li, Y., Shuai, W., Kuang, C., Peng, Q., Shi, W., et al. (2017) · International Journal of Cancer · doi:10.1002/ijc.31169 · Cited by 25 · see citing works

Phosphatase Specificity and Pathway Insulation in Signaling Networks

Rowland, M. A., Harrison, B., & Deeds, E. J. (2015) · Biophysical Journal · doi:10.1016/j.bpj.2014.12.011 · Cited by 24 · see citing works

Integrative analysis reveals distinct subtypes with therapeutic implications in KRAS-mutant lung adenocarcinoma

Liu, K., Guo, J., Liu, K., Fan, P., Zeng, Y., Xu, C., Zhong, J., Li, Q., & Zhou, Y. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.09.034 · Cited by 23 · see citing works

miR-194 is a negative regulator of GEF-H1 pathway in melanoma

Guo, B., Hui, Q., Zhang, Y., Chang, P., & Tao, K. X. (2016) · Oncology Reports · doi:10.3892/or.2016.5020 · Cited by 20 · see citing works

Guanine nucleotide exchange factors for Rho GTPases (RhoGEFs) as oncogenic effectors and strategic therapeutic targets in metastatic cancer

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Identification of protein phosphatase 2A as an interacting protein of leucine-rich repeat kinase 2

Athanasopoulos, P. S., Jacob, W., Neumann, S., Kutsch, M., Wolters, D. A., Tan, E. K., Bichler, Z., Herrmann, C., & Heumann, R. (2016) · Biological Chemistry · doi:10.1515/hsz-2015-0189 · Cited by 19 · see citing works

New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling

Erickson, K. E., Rukhlenko, O. S., Posner, R. G., Hlavacek, W. S., & Kholodenko, B. Ν. (2018) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2018.02.008 · Cited by 20 · see citing works

Moesin (MSN) as a Novel Proteome-Based Diagnostic Marker for Early Detection of Invasive Bladder Urothelial Carcinoma in Liquid-Based Cytology

Park, J. H., Lee, C., Han, D., Lee, J. S., Lee, K. M., Song, M. J., Kim, K., Lee, H., Moon, K. C., Kim, Y., et al. (2020) · Cancers · doi:10.3390/cancers12041018 · Cited by 19 · see citing works

A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis

Zhang, Q., Cao, C., Gong, W., Bao, K., Wang, Q., Wang, Y., Bi, L., Ma, S., Zhao, J., Liu, L., et al. (2020) · Theranostics · doi:10.7150/thno.46878 · Cited by 18 · see citing works

Altered expression of cellular proliferation, apoptosis and the cell cycle-related genes in lung cancer cells with acquired resistance to EGFR tyrosine kinase inhibitors

Lee, T., Jeong, E., Min, I. J., Kim, S. Y., Kim, H.-R., & Kim, C. H. (2017) · Oncology Letters · doi:10.3892/ol.2017.6428 · Cited by 17 · see citing works

Guanine nucleotide exchange factor -H1 promotes inflammatory cytokine production and intracellular mycobacterial elimination in macrophages

Wang, H., Wang, J., Yang, J., Yang, X., He, J., Wang, R., Liu, S., Zhou, L., & Ma, L. (2017) · Cell Cycle · doi:10.1080/15384101.2017.1347739 · Cited by 15 · see citing works

Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor

Lorenzo‐Martín, L. F., Rodríguez‐Fdez, S., Fabbiano, S., Abad, A., García-Macías, M. C., Dosil, M., Cuadrado, M., Robles‐Valero, J., & Bustelo, X. R. (2020) · Oncogene · doi:10.1038/s41388-020-1353-x · Cited by 16 · see citing works

Therapeutic Validation of GEF-H1 Using a De Novo Designed Inhibitor in Models of Retinal Disease

Mills, C., Hemkemeyer, S. A., Alimajstorovic, Z., Bowers, C. E., Eskandarpour, M., Greenwood, J., Calder, V. L., Chan, A. W. E., Gane, P. J., Selwood, D. L., et al. (2022) · Cells · doi:10.3390/cells11111733 · Cited by 15 · see citing works

The Inhibition of Wnt Restrain KRASG12V-Driven Metastasis in Non-Small-Cell Lung Cancer

Hung, P.-S., Huang, M.-H., Kuo, Y., & Yang, J. C. (2020) · Cancers · doi:10.3390/cancers12040837 · Cited by 14 · see citing works

Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids

Gebregiworgis, T., Marshall, C. B., Nishikawa, T., Radulovich, N., Sandí, M. J., Fang, Z., Rottapel, R. K., Tsao, M., & Ikura, M. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b13703 · Cited by 13 · see citing works

Microbial recognition by GEF-H1 controls IKKε mediated activation of IRF5

Zhao, Y., Zagani, R., Park, S., Yoshida, N., Shah, P., & Reinecker, H. (2019) · Nature Communications · doi:10.1038/s41467-019-09283-x · Cited by 13 · see citing works

ARHGEF38 as a novel biomarker to predict aggressive prostate cancer

Liu, K., Wang, A., Ran, L., Zhang, W., Song, J., Wang, Y., Zhang, X., Liu, G., Sen, W., & Song, F. (2019) · Genes & Diseases · doi:10.1016/j.gendis.2019.03.004 · Cited by 13 · see citing works

Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality

van Pelt, J. F., Meeusen, B., Derua, R., Guffens, L., Cutsem, E. V., Janssens, V., & Verslype, C. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04145-z · Cited by 11 · see citing works

High ARHGEF2 (GEF-H1) Expression is Associated with Poor Prognosis Via Cell Cycle Regulation in Patients with Pancreatic Cancer

Nakao, Y., Nakagawa, S., Yamashita, Y., Umezaki, N., Okamoto, Y., Ogata, Y., Yasuda‐Yoshihara, N., Itoyama, R., Yusa, T., Yamashita, K., et al. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-020-09383-9 · Cited by 14 · see citing works

Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse

Nobis, M., Herrmann, D., Warren, S. C., Strathdee, D., Cox, T. R., Anderson, K. I., & Timpson, P. (2018) · Small GTPases · doi:10.1080/21541248.2018.1438024 · Cited by 12 · see citing works

Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis

Chan, D. C. H., Xu, J., Vujovic, A., Wong, N., Gordon, V. D., de Rooij, L. P. M. H., Moreira, S., Joyce, C. E., Rose, J. L., Sandí, M. J., et al. (2021) · Blood Advances · doi:10.1182/bloodadvances.2020002539 · Cited by 10 · see citing works

Regulation of the RhoA exchange factor GEF-H1 by profibrotic stimuli through a positive feedback loop involving RhoA, MRTF, and Sp1

Venugopal, S., Dan, Q., Theivakadadcham, V. S. S., Wu, B., Kofler, M., Layne, M. D., Connelly, K. A., Rzepka, M. F., Friedberg, M. K., Kapùs, A., et al. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00088.2024 · Cited by 12 · see citing works

Akt-mediated Ephexin1–Ras interaction promotes oncogenic Ras signaling and colorectal and lung cancer cell proliferation

Kim, J., Jeon, Y. J., Lim, S., Ryu, J., Lee, J.-H., Chang, I. Y., & You, H. J. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-04332-0 · Cited by 11 · see citing works

Regulation of cortical stability by RhoGEF3 in mitotic sensory organ precursor cells inDrosophila

Couturier, L., Mazouni, K., Bernard, F., Besson, C., Reynaud, E., & Schweisguth, F. (2017) · Biology Open · doi:10.1242/bio.026641 · Cited by 11 · see citing works

KSR1 Mediates Small Cell Lung Carcinoma Tumor Initiation and Cisplatin Resistance

Chatterjee, D., Svoboda, R. A., Huisman, D. H., Drapkin, B. J., Vieira, H. M., Rao, C., Askew, J. W., Fisher, K. W., & Lewis, R. E. (2025) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-24-0652 · Cited by 10 · see citing works

Co-dependency between KRAS addiction and ARHGEF2 promotes an adaptive escape from MAPK pathway inhibition

Kent, O. A., Sandí, M. J., & Rottapel, R. K. (2017) · Small GTPases · doi:10.1080/21541248.2017.1337545 · Cited by 11 · see citing works

Androgen deprivation restores ARHGEF2 to promote neuroendocrine differentiation of prostate cancer

Chen, X., Shao, Y., Wei, W., Zhu, S., Li, Y., Chen, Y., Li, H., Tian, H., Sun, G., Niu, Y., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05366-8 · Cited by 10 · see citing works

Upregulation of the GEF-H1 pathway after transient cerebral ischemia

Luo, T., Roman, P., Liu, C., Sun, X., Park, Y., & Hu, B. R. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.10.016 · Cited by 10 · see citing works

High‐throughput workflow for identification of phosphorylated peptides by LC‐MALDI‐TOF/TOF‐MS coupled to in situ enrichment on MALDI plates functionalized by ion landing

Krásný, L., Pompach, P., Strnadová, M., Hynek, R., Vališ, K., Havlı́ček, V., Novák, P., & Volný, M. (2015) · Journal of Mass Spectrometry · doi:10.1002/jms.3586 · Cited by 9 · see citing works

A Gene Expression High-Throughput Screen (GE-HTS) for Coordinated Detection of Functionally Similar Effectors in Cancer

Rao, C., Huisman, D. H., Vieira, H. M., Frodyma, D. E., Neilsen, B. K., Chakraborty, B., Hight, S. K., White, M. A., Fisher, K. W., & Lewis, R. E. (2020) · Cancers · doi:10.3390/cancers12113143 · Cited by 8 · see citing works

Interfering with the expression of EEF1D gene enhances the sensitivity of ovarian cancer cells to cisplatin

Qia, X., Liu, Y., Wang, S., Wang, J., Liu, L., Xu, Y., & Qin, Y. (2022) · BMC Cancer · doi:10.1186/s12885-022-09699-7 · Cited by 7 · see citing works

Construction of a combined random forest and artificial neural network diagnosis model to screening potential biomarker for hepatoblastoma

Liu, S., Zheng, Q., Zhang, R., Li, T., & Zhan, J. (2022) · Pediatric Surgery International · doi:10.1007/s00383-022-05255-3 · Cited by 7 · see citing works

Autism associated mutations in β2 subunit of voltage-gated calcium channels constitutively activate gene expression

Trus, M., Servili, E., Taieb-Cohen, T., & Atlas, D. (2022) · Cell Calcium · doi:10.1016/j.ceca.2022.102672 · Cited by 6 · see citing works

Dynamic Coupling of MAPK Signaling to the Guanine Nucleotide Exchange Factor GEF-H1

Leguay, K., & Kent, O. A. (2025) · OncoTargets and Therapy · doi:10.2147/ott.s496228 · Cited by 6 · see citing works

Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling

Li, D., Miermont, A. M., Sable, R. V., Quadri, H. S., Griner, L. A. M., Martin, S. E., Odzorig, T., De, S., Ferrer, M., Powers, A. S., et al. (2023) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-21-1036 · Cited by 5 · see citing works

Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding

Jiang, Y., Jiang, H., Zhou, S., Meng, B., Liu, Z., & Ouyang, S. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.01.150 · Cited by 5 · see citing works

Guanine nucleotide exchange factor H1 can be a new biomarker of melanoma

Kai, T., Guo, B., Zhang, Y., Hui, Q., Chang, P., & Shi, J. (2016) · Biologics · doi:10.2147/btt.s109643 · Cited by 6 · see citing works

Plinabulin, a microtubule destabilising agent, in non-small-cell lung cancer: lessons from the DUBLIN-3 trial

Rosell, R., González‐Cao, M., & Molina‐Vila, M. Á. (2024) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(24)00191-7 · Cited by 4 · see citing works

The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis

Sahasrabuddhe, A. A., Chen, X., Ma, K., Wu, R., Liang, H.-C., Kapoor, R., Chhipa, R. R., Önder, Ö., McFetridge, C., Arnam, J. S. V., et al. (2025) · Cancer Discovery · doi:10.1158/2159-8290.cd-24-0442 · Cited by 4 · see citing works

Keratinocyte-derived VEGF-A is an essential pro-migratory autocrine mediator, acting through the KDR/GEF-H1/RhoA pathway

Maksimoska, V., Dan, Q., Rambharack, N., & Szászi, K. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1601887 · Cited by 3 · see citing works

Guanine nucleotide exchange factors and colon neoplasia

Njei, L., Moura, N. S., Schledwitz, A., Griffiths, K., Cheng, K., & Raufman, J. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1489321 · Cited by 3 · see citing works

Bacteroides acidifaciens enriched by KRAS mutation promotes colorectal tumorigenesis

Jiao, Y., Cheng, C. H., Gao, X., Li, W., Ji, F., Liang, C., Huang, P., Ko, L. H., Ye, L., Kam, I. C. H., et al. (2026) · Cell Host & Microbe · doi:10.1016/j.chom.2026.08.010 · Cited by 2 · see citing works

GEF-H1 drives breast cancer cells to tumor progression

Chávez, L. F., Schweitzer, K., Alonso, E. G., Ferronato, M. J., Fermento, M. E., Alonso, E. N., Facchinetti, M. M., Curino, A. C., & Coló, G. P. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2025.167816 · Cited by 1 · see citing works

KSR1 is a scaffold for the Hippo signaling pathway

Sayedyahossein, S., Sait, M. R. B., Li, Z., Banerjee, R., Tran, A. D., Thines, L., Karimi, M., Bahmani, M., Mishan, N., Borzou, P., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-09009-4 · Cited by 1 · see citing works

Poxvirus infection triggers remodeling of host m⁶A epitranscriptome and benefits from the m⁶A regulatory responses

Kwon, T., Morales, D. P., Mikolitis, A. S., Mach, P. M., Gleasner, C. D., & Micheva‐Viteva, S. (2026) · Virology Journal · doi:10.1186/s12985-026-03160-y · Cited by 1 · see citing works

GAK antagonises ROCK-dependent regulation of actomyosin dynamics

Hiramoto, M., Takano, N., Kokuba, H., Kazama, H., Hino, H., Handa, H., & Miyazawa, K. (2026) · Journal of Cell Science · doi:10.1242/jcs.264117 · Cited by 1 · see citing works

Amplifying colorectal cancer progression: impact of a PDIA4/SP1 positive feedback loop by circPDIA4 sponging miR-9-5p

Zhuang, Y., Ai, Y., Li, P., Yue, X., Li, Y., Shan, L., Wang, T., Zhao, P., & Jin, X. (2024) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2024.0112 · Cited by 1 · see citing works

Prognostic and Immunotherapeutic Role of TACC3 in Pancancer and Its Impact on Proliferation and Docetaxel Resistance in Lung Adenocarcinoma

Xu, J., Zhu, Y., Liu, Q., Xu, C., Wang, W., Sun, J., Ding, X., Liu, B., & Chen, L. (2024) · Oncology · doi:10.1159/000542450 · Cited by 1 · see citing works

Taxane-induced conformational changes in the microtubule lattice activate GEF-H1-dependent RhoA signalling

Meiring, J. C. M., Mahapatra, V., Liu, R., Gravett, M. S. C., Morren, D., Saunders, H. A. J., Choi, S. R., Pelster José, A., Karhanova, A., Metallidou, I., et al. (2026) · Nature Cell Biology · doi:10.1038/s41556-026-02079-4

Data from Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling

Li, D., Miermont, A. M., Sable, R. V., Quadri, H. S., Griner, L. A. M., Martin, S. E., Odzorig, T., De, S., Ferrer, M., Powers, A. S., et al. (2023) · doi:10.1158/1541-7786.c.6534771.v1

Data from Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling

Li, D., Miermont, A. M., Sable, R. V., Quadri, H. S., Griner, L. A. M., Martin, S. E., Odzorig, T., De, S., Ferrer, M., Powers, A. S., et al. (2023) · doi:10.1158/1541-7786.c.6534771.v2

Inhibition of GEF-H1-RhoA signaling in inflammation with a stapled peptide mimicry of the RhoA 67-78 helixPreprint

Gathmann, C., Liu, T., Yang, S., Wang, W. C., Chan, A. W. E., Matter, K., Balda, M. S., & Selwood, D. L. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.18.624118

Genetic Mutations Associated With NSCLC and Molecular Subtypes of NSCLC

Vijayakumar, P., Mubarak, M., Palani, A., & Sindhuja, S. (2025) · IGI Global eBooks · doi:10.4018/979-8-3373-2096-0.ch002

Additional file 2 of Interfering with the expression of EEF1D gene enhances the sensitivity of ovarian cancer cells to cisplatin

Qia, X., Liu, Y., Wang, S., Wang, J., Liu, L., Xu, Y., & Qin, Y. (2022) · Figshare · doi:10.6084/m9.figshare.20023183

Additional file 5 of Interfering with the expression of EEF1D gene enhances the sensitivity of ovarian cancer cells to cisplatin

Qia, X., Liu, Y., Wang, S., Wang, J., Liu, L., Xu, Y., & Qin, Y. (2022) · Figshare · doi:10.6084/m9.figshare.20023192

Additional file 3 of Interfering with the expression of EEF1D gene enhances the sensitivity of ovarian cancer cells to cisplatin

Qia, X., Liu, Y., Wang, S., Wang, J., Liu, L., Xu, Y., & Qin, Y. (2022) · Figshare · doi:10.6084/m9.figshare.20023186

Additional file 4 of Interfering with the expression of EEF1D gene enhances the sensitivity of ovarian cancer cells to cisplatin

Qia, X., Liu, Y., Wang, S., Wang, J., Liu, L., Xu, Y., & Qin, Y. (2022) · Figshare · doi:10.6084/m9.figshare.20023189

Additional file 1 of Interfering with the expression of EEF1D gene enhances the sensitivity of ovarian cancer cells to cisplatin

Qia, X., Liu, Y., Wang, S., Wang, J., Liu, L., Xu, Y., & Qin, Y. (2022) · Figshare · doi:10.6084/m9.figshare.20023180

Additional file 1 of Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality

van Pelt, J., Meeusen, B., Derua, R., Guffens, L., Cutsem, E. V., Janssens, V., & Verslype, C. (2024) · Figshare · doi:10.6084/m9.figshare.26588817

The MICAL family at the Rho–Rab interface: coordinating actin dynamics through oxidation and scaffolding

Micovic, K., & Olson, M. F. (2026) · Biochemical Journal · doi:10.1042/bcj20250118

Mutant KRAS favors a microbe that signals back

Jiao, N., Zhu, L., & Zhu, R. (2026) · Cell Host & Microbe · doi:10.1016/j.chom.2026.09.007

Abstract B31: The RhoGEF GEF-H1 is required for RAS oncogene-driven pancreatic cancer

Cullis, J. E., Meiri, D., Sandí, M. J., Kent, O. A., Medrano, M., Mokady, D., Tsao, M., Gingras, A., & Rottapel, R. K. (2014) · Molecular Cancer Research · doi:10.1158/1557-3125.rasonc14-b31

A New Target to Halt RAS

Ferrarelli, L. K. (2014) · Science Signaling · doi:10.1126/scisignal.2005180

Dynamic Coupling of MAPK Signaling to the Guanine Nucleotide Exchange Factor GEF-H1

Leguay, K., & Kent, O. A. (2025) · OncoTargets and Therapy · doi:10.2147/ott.s496228 · Cited by 6 · see citing works

Abstract A14: Transactivation of the Rho-guanine exchange factor ARHGEF2 by oncogenic K-RAS potentiates invasion-migration in pancreatic ductal adenocarcinoma.

Kent, O. A., Sandí, M. J., & Rottapel, R. (2014) · Molecular Cancer Research · doi:10.1158/1557-3125.rasonc14-a14

KSR induces RAS‐independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors

Paniagua, G., Jacob, H. K. C., Brehey, O., García‐Alonso, S., Lechuga, C. G., Pons, T., Musteanu, M., Guerra, C., Drosten, M., & Barbacid, M. (2022) · Molecular Oncology · doi:10.1002/1878-0261.13213 · Cited by 34 · see citing works