The role of the Atg1/ULK1 complex in autophagy regulation

TOR signaling in growth and metabolism

Wullschleger, S., Loewith, R., & Hall, M. N. (2006) · Cell · doi:10.1016/j.cell.2006.01.016 · Cited by 5,787

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H., & Johansen, T. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200507002 · Cited by 3,276

Defining the role of mTOR in cancer

Guertin, D. A., & Sabatini, D. M. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.05.008 · Cited by 2,833

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Ravikumar, B., Vacher, C., Berger, Z., Davies, J. E., Luo, S., Oroz, L. G., Scaravilli, F., Easton, D. F., Duden, R., O'Kane, C. J., et al. (2004) · Nature Genetics · doi:10.1038/ng1362 · Cited by 2,347

Autophagosome formation: core machinery and adaptations

Xie, Z., & Klionsky, D. J. (2007) · Nature Cell Biology · doi:10.1038/ncb1007-1102 · Cited by 2,237

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

Komatsu, M., Waguri, S., Koike, M., Sou, Y.-S., Ueno, T., Hara, T., Mizushima, N., Iwata, J.-I., Ezaki, J., Murata, S., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.035 · Cited by 2,124

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

Hosokawa, N., Hara, T., Kaizuka, T., Kishi, C., Takamura, A., Miura, Y., Iemura, S.-I., Natsume, T., Takehana, K., Yamada, N., et al. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-12-1248 · Cited by 2,076

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Jung, C. H., Jun, C. B., Ro, S.-H., Kim, Y.-M., Otto, N. M., Cao, J., Kundu, M., & Kim, D.-H. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-12-1249 · Cited by 2,025

Autophagy: molecular machinery for self-eating

Yorimitsu, T., & Klionsky, D. J. (2005) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401765 · Cited by 1,566

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

Ganley, I. G., Lam, D. H., Wang, J., Ding, X., Chen, S., & Jiang, X. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m900573200 · Cited by 1,447

The transcription factor p8 regulates autophagy during diapause embryo formation in Artemia parthenogenetica

Lin, C., Jia, S., Yang, F., Jia, W.-H., Yu, X.-J., Yang, J., & Yang, W. (2016) · Cell Stress and Chaperones · doi:10.1007/s12192-016-0692-6 · Cited by 17

Akt/mTOR and AMPK signaling pathways are responsible for liver X receptor agonist GW3965-enhanced gefitinib sensitivity in non-small cell lung cancer cell lines

Wang, Q., Shen, B., Qin, X., Liu, S., & Feng, J. (2019) · Translational Cancer Research · doi:10.21037/tcr.2018.12.34 · Cited by 17

Rola autofagii w komórkach nowotworowych: charakterystyka wzajemnych zależności pomiędzy procesami autofagii i apoptozy; modulacja autofagii jako nowa strategia terapeutyczna w leczeniu glejaków

Ciechomska, I. A. (2018) · Postępy Biochemii · doi:10.18388/pb.2018_121 · Cited by 16

Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer’s disease pathology

Pan, J., Wang, P.-J., Zhang, J., Knapskog, A., Watne, L. O., Wang, H.-L., Lagartos-Donate, M. J., Lautrup, S., Mao, L.-P., Wang, Q., et al. (2026) · Nature Aging · doi:10.1038/s43587-026-01108-z · Cited by 20

Deubiquitinase USP10 promotes osteosarcoma autophagy and progression through regulating GSK3β-ULK1 axis

Feng, Z., Ou, Y., Deng, X., Deng, M., Yan, X., Chen, L., Zhou, F., & Hao, L. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01291-9 · Cited by 18

Basal Autophagy and Feedback Activation of Akt Are Associated with Resistance to Metformin-Induced Inhibition of Hepatic Tumor Cell Growth

Yang, H., Peng, Y., Ni, H., Li, Y., Shi, Y., Ding, W., & Fan, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0130953 · Cited by 16

Dietary restriction regimens for fighting kidney disease: Insights from rodent studies

Singh, G., & Krishan, P. (2019) · Experimental Gerontology · doi:10.1016/j.exger.2019.110738 · Cited by 16

AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo

Ribas, V. T., Vahsen, B. F., Tatenhorst, L., Estrada, V., Dambeck, V., Almeida, R. A., Bähr, M., Michel, U., Koch, J. C., Müller, H. W., et al. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03503-3 · Cited by 17

The role of extracellular vesicles in podocyte autophagy in kidney disease

Sun, B.-C., Zhai, S.-B., Zhang, L., & Sun, G. (2021) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-020-00594-z · Cited by 16

GCN2 upregulates autophagy in response to short-term deprivation of a single essential amino acid

Maurin, A., Parry, L., B'Chir, W., Carraro, V., Coudy‐Gandilhon, C., Chaouki, G., Chaveroux, C., Mordier, S., Martinie, B. G., Reinhardt, V., et al. (2022) · Autophagy Reports · doi:10.1080/27694127.2022.2049045 · Cited by 19

Transient overexpression of Werner protein rescues starvation induced autophagy in Werner syndrome cells

Maity, J., Bohr, V. A., Laskar, A., & Karmakar, P. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.09.007 · Cited by 16

The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion

Lin, M. G., Schöneberg, J., Davies, C., Ren, X., & Hurley, J. H. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e17-04-0258 · Cited by 16

Autophagy and Schizophrenia

Yang, Y., & Xu, L. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-4272-5_13 · Cited by 15

CircARHGAP12 Triggers Mesenchymal Stromal Cell Autophagy to Facilitate its Effect on Repairing Diabetic Wounds by Sponging miR-301b-3p/ATG16L1 and miR-301b-3p/ULK2

Meng, F., Shen, F., Ling, H., Jin, P., Zhou, D., & Li, Q. (2021) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2021.11.039 · Cited by 15

Amino Acid‐Starved Cancer Cells Utilize Macropinocytosis and Ubiquitin‐Proteasome System for Nutrient Acquisition

Wang, T., Zhang, Y., Liu, Y., Huang, Y., & Wang, W. (2023) · Advanced Science · doi:10.1002/advs.202304791 · Cited by 15

Autophagy: a necessary evil in cancer and inflammation

Mathur, A., Ritu, R., Chandra, P., & Das, A. (2024) · 3 Biotech · doi:10.1007/s13205-023-03864-w · Cited by 16

Dysregulation of autophagy in gastric carcinoma: Pathways to tumor progression and resistance to therapy

Wen, W., Ertaş, Y. N., Erdem, A., & Zhang, Y. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216857 · Cited by 18

Exploring the potential of Lactocaseibacillus rhamnosus PMC203 in inducing autophagy to reduce the burden of Mycobacterium tuberculosis

Rahim, M. A., Seo, H., Kim, S., Barman, I., Ghorbanian, F., Hossain, M. S., Shuvo, M. S. H., Lee, S., & Song, H. (2024) · Medical Microbiology and Immunology · doi:10.1007/s00430-024-00794-z · Cited by 18

Three-Axis Model for Atg Recruitment in Autophagy againstSalmonella

Noda, T., Kageyama, S., Fujita, N., & Yoshimori, T. (2012) · International Journal of Cell Biology · doi:10.1155/2012/389562 · Cited by 15

Upregulation of ULK1 expression in PC-3 cells following tumor protein P53 transfection by sonoporation

Wang, Y., CHEN, Y.-N., Zhang, W., Yu, Y., Bai, W., Shen, E., & Hu, B. Q. (2015) · Oncology Letters · doi:10.3892/ol.2015.3946 · Cited by 16

Nrf2 but not autophagy inhibition is associated with the survival of wild-type epidermal growth factor receptor non-small cell lung cancer cells

Zhou, Y., Li, Y., Ni, H., Ding, W., & Zhong, H. (2016) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2016.09.010 · Cited by 15

Small GTPases controlling autophagy-related membrane traffic in yeast and metazoans

Takáts, S., Boda, A., Csizmadia, T., & Juhász, G. (2016) · Small GTPases · doi:10.1080/21541248.2016.1258444 · Cited by 15

Autophagy as a self-digestion signal in human cancers: Regulation by microRNAs in affecting carcinogenesis and therapy response

Kadhim, M. M., Ramírez‐Coronel, A. A., Jalil, A. T., Talib, H. A., Gupta, J., Jawhar, Z. H., Saleh, M. M., Pandey, V., Zhang, X., & Khan, H. Z. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106695 · Cited by 17

See How I Eat My Greens—Autophagy in Plant Cells

Chung, T. (2011) · Journal of Plant Biology · doi:10.1007/s12374-011-9176-5 · Cited by 15

Uncoupling AMPK from autophagy: a foe that hinders the beneficial effects of metformin treatment on metabolic syndrome-associated atherosclerosis? Focus on “Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells”

Ding, W. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00375.2014 · Cited by 15

ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney disease

Yanagi, T., Kikuchi, H., Takeuchi, K., Susa, K., Mori, T., Chiga, M., Yamamoto, K., Furukawa, A., Kanazawa, T., Kato, Y., et al. (2024) · Kidney International · doi:10.1016/j.kint.2024.08.024 · Cited by 14

Integration of Physiological, Transcriptomic and Metabolomic Reveals Molecular Mechanism of Paraisaria dubia Response to Zn2+ Stress

Wang, Y., Tong, L., Li, Y., Liu, M., Du, Y., Yang, L., Ren, B., & Guo, D. (2023) · Journal of Fungi · doi:10.3390/jof9070693 · Cited by 14

Fundamental mechanisms of cell death for polycystic ovary syndrome

Li, Y., Peng, Y., Yang, Y., Xu, N., Shi, T., Liu, R., Luan, Y., & Yin, C.-H. (2025) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2025.102043 · Cited by 14

Modulation of Autophagy-Like Processes by Tumor Viruses

Mack, H. I. D., & Münger, K. (2012) · Cells · doi:10.3390/cells1030204 · Cited by 14

The Core Molecular Machinery of Autophagosome Formation

Jin, M., & Klionsky, D. J. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6561-4_2 · Cited by 15

Autophagy in white matter disorders of the CNS : mechanisms and therapeutic opportunities

Nutma, E., Marzin, M. C., Cillessen, S. A. G. M., & Amor, S. (2020) · The Journal of Pathology · doi:10.1002/path.5576 · Cited by 15

Dualistic role of autophagy in cancer progression

Turek, K., Jarocki, M., Kulbacka, J., & Saczko, J. (2021) · Advances in Clinical and Experimental Medicine · doi:10.17219/acem/141191 · Cited by 14

The effect of lactoferrin on ULK1 and ATG13 genes expression in breast cancer cell line MCF7 and bioinformatics studies of protein interaction between lactoferrin and the autophagy initiation complex

Karabi, Z., Moradian, F., & Kheirabadi, M. (2022) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-022-01097-x · Cited by 14

ULK2 Ser 1027 Phosphorylation by PKA Regulates Its Nuclear Localization Occurring through Karyopherin Beta 2 Recognition of a PY-NLS Motif

Shin, S., Lee, E. J., Chun, J., Hyun, S., & Kang, S. S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127784 · Cited by 16

A role for autophagy in carotid atherosclerosis

Alloza, I., Goikuria, H., Freijo, M. D. M., & Vandenbroeck, K. (2016) · European Stroke Journal · doi:10.1177/2396987316674085 · Cited by 14

ULK1 negatively regulates Wnt signaling by phosphorylating Dishevelled

Hwang, S.-H., Bang, S., Kang, K. S., Kang, D., & Chung, J. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.11.139 · Cited by 13

Cdc14 spatiotemporally dephosphorylates Atg13 to activate autophagy during meiotic divisions

Feng, W., Argüello‐Miranda, O., Qian, S., & Wang, F. (2022) · The Journal of Cell Biology · doi:10.1083/jcb.202107151 · Cited by 14

Mass Spectrometry Detects Sphingolipid Metabolites for Discovery of New Strategy for Cancer Therapy from the Aspect of Programmed Cell Death

Shi, M., Tang, C., Wu, J.-X., Ji, B.-W., Gong, B., Wu, X., & Wang, X. (2023) · Metabolites · doi:10.3390/metabo13070867 · Cited by 14

Understanding the molecular regulatory mechanisms of autophagy in lung disease pathogenesis

Lin, L., Lin, Y., Han, Z., Wang, K., Zhou, S., Wang, Z., Wang, S., & Chen, H. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1460023 · Cited by 13

Neuroprotective effects of phytochemicals through autophagy modulation in ischemic stroke

Ahmadzadeh, A. M., Pourbagher‐Shahri, A. M., & Forouzanfar, F. (2025) · Inflammopharmacology · doi:10.1007/s10787-024-01606-9 · Cited by 14

Autophagy, ER-phagy and ER Dynamics During Cell Differentiation

Cillo, M., Buonomo, V., Vainshtein, A., & Grumati, P. (2025) · Journal of Molecular Biology · doi:10.1016/j.jmb.2025.169151 · Cited by 14

Insights into autophagosome biogenesis from in vitro reconstitutions

Turco, E., & Martens, S. (2016) · Journal of Structural Biology · doi:10.1016/j.jsb.2016.04.005 · Cited by 13

Induction of Autophagy

Yeganeh, B., Jäger, R., Gorman, A. M., Samali, A., & Ghavami, S. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801043-3.00005-4 · Cited by 17

Autophagic Flux Is Regulated by Interaction Between the C-terminal Domain of PATCHED1 and ATG101

Chen, X., Morales-Alcala, C. C., & Galdo, N. A. R. (2018) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-17-0597 · Cited by 14

The role of 19S proteasome associated deubiquitinases in activity-dependent hippocampal synaptic plasticity

Yun, D., Zhuang, Y., Kreutz, M. R., & Behnisch, T. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.01.043 · Cited by 13

Bone marrow mesenchymal stem cells protect against n-hexane-induced neuropathy through beclin 1-independent inhibition of autophagy

Hao, J., Li, S., Shi, X., Qian, Z., Sun, Y., Wang, D., Zhou, X., Qu, H., Hu, S., Zuo, E., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-22857-x · Cited by 13

Molecular mechanisms of interplay between autophagy and metabolism in cancer

Raj, S., Chandel, V., Kumar, A. J., Kesari, K. K., Asthana, S., Ruokolainen, J., Kamal, M. A., & Kumar, D. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118184 · Cited by 14

Post-transcriptional regulation ofATG1is a critical node that modulates autophagy during distinct nutrient stresses

Lahiri, V., Metur, S. P., Hu, Z., Song, X., Mari, M. C., Hawkins, W. D., Bhattarai, J., Delorme‐Axford, E., Reggiori, F., Tang, D., et al. (2021) · Autophagy · doi:10.1080/15548627.2021.1997305 · Cited by 14

An A. thaliana mutant lacking all nine ATG8 isoforms provides genetic evidence for functional specialization of ATG8 in plants

Chiaro, A. D., Grujic, N., Zhao, J., Papareddy, R. K., Gao, P., Ma, J., Löfke, C., Bhattacharya, A., Gruetzner, R., Bourguet, P., et al. (2025) · Journal of Cell Science · doi:10.1242/jcs.263803 · Cited by 16

Involvement of the Autophagy Protein Atg1 in Development and Virulence in Botryosphaeria dothidea

Liu, N., Zhu, M., Zhang, Y., Wang, Z., Li, B., & Ren, W. (2022) · Journal of Fungi · doi:10.3390/jof8090904 · Cited by 12

M2 Muscarinic Receptor Stimulation Induces Autophagy in Human Glioblastoma Cancer Stem Cells via mTOR Complex-1 Inhibition

Guerriero, C., Manfredelli, M., Matera, C., Iuzzolino, A., Conti, L., Dallanoce, C., Amici, M. D., Trisciuoglio, D., & Tata, A. M. (2023) · Cancers · doi:10.3390/cancers16010025 · Cited by 13

Effect and Mechanism of Rapamycin on Cognitive Deficits in Animal Models of Alzheimer’s Disease: A Systematic Review and Meta-analysis of Preclinical Studies

Cai, J., Xie, D., Kong, F., Zhai, Z., Zhu, Z., Zhao, Y., Xu, Y., & Sun, T. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-231249 · Cited by 13

Mechanism of podophyllotoxin-induced ovarian toxicity via the AMPK/TSC1/mTOR/ULK1 axis in rats on the basis of toxicological evidence chain (TEC) concept

Li, J., Zhang, Y., Wei, M., He, J., Ma, H., Chen, Z., Duan, J., & Liu, C. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117617 · Cited by 12

Host immunity and intracellular bacteria evasion mechanisms: Enhancing host-directed therapies with drug delivery systems

Cai, J., Zhou, H., Liu, M., Zhang, D., Lv, J., Xue, H., Zhou, H., & Zhang, W. (2025) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2025.107492 · Cited by 12

Inhibition of autophagy sensitizes lignan-induced endoplasmic reticulum stress-mediated cell death

Kwon, J., Lee, Y., Jeong, J. H., Ryu, J., & Kim, K. I. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.03.081 · Cited by 12

The sorting nexin FgAtg20 is involved in the Cvt pathway, non‐selective macroautophagy, pexophagy and pathogenesis in Fusarium graminearum

Lv, W., Xu, Z., Talbot, N. J., & Wang, Z. (2020) · Cellular Microbiology · doi:10.1111/cmi.13208 · Cited by 13

The ULK1 kinase, a necessary component of the pro-regenerative and anti-aging machinery in Hydra

Suknovic, N., Tomczyk, S., Colevret, D., Perruchoud, C., & Galliot, B. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111414 · Cited by 13

Autophagy based cellular physiological strategies target oncogenic progression

Kumar, P., Jagtap, Y. A., Patwa, S. M., Kinger, S., Dubey, A. R., Prajapati, V. K., Dhiman, R., Poluri, K. M., & Mishra, A. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30567 · Cited by 13

Playing the Devil’s Advocate: Should We Give a Second Chance to mTOR Inhibition in Renal Clear Cell Carcinoma? – ie Strategies to Revert Resistance to mTOR Inhibitors

Pezzicoli, G., Filoni, E., Gernone, A., Cosmai, L., Rizzo, M., & Porta, C. (2021) · Cancer Management and Research · doi:10.2147/cmar.s267220 · Cited by 12

Autophagy, a Highly Regulated Intracellular System Essential to Skeletal Muscle Homeostasis — Role in Disease, Exercise and Altitude Exposure

Sanchez, A. M. J., Candau, R. B., Raibon, A., & Bernardi, H. (2015) · InTech eBooks · doi:10.5772/60698 · Cited by 13

Mechanistically Dissecting Autophagy: Insights from In Vitro Reconstitution

Brier, L. W., Zhang, M., & Ge, L. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.02.024 · Cited by 11

Autophagy and its current relevance to the diagnosis and clinical management of esophageal diseases

Langer, R., Streutker, C., & Swanson, P. E. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13190 · Cited by 12

Increased Autophagy Levels Mediate Cisplatin Resistance in Cisplatin-Resistant Cells While Also Rendering Them Vulnerable to Autophagy Induction

Duan, G., Song, Z., Qi, M., Bai, X., Wang, J., Zhang, Y., Zou, X., Guo, Q., & Wan, P. (2018) · BioMed Research International · doi:10.1155/2018/1736738 · Cited by 12

Inhibition of COX2/PGD2-Related Autophagy Is Involved in the Mechanism of Brain Injury in T2DM Rat

Yang, Y., Chen, Q., Zhao, Q., Luo, Y., Xu, Y., Du, W., Wang, H., Li, H., Lu, Y., Hu, C., et al. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00068 · Cited by 12

Non-coding RNAs regulate autophagy process via influencing the expression of associated protein

Zhao, Y., Wang, Z., Zhang, W., & Zhang, L. (2019) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2019.11.009 · Cited by 12

Dysfunction of two lysosome degradation pathways of α-synuclein in Parkinson’s disease: potential therapeutic targets?

Jiang, T., & Chen, S. (2012) · Neuroscience Bulletin · doi:10.1007/s12264-012-1263-1 · Cited by 12

To Live or Die: Autophagy in Plants

Floyd, B. E., Pu, Y., Soto-Burgos, J., & Bassham, D. C. (2015) · Springer eBooks · doi:10.1007/978-3-319-21033-9_11 · Cited by 11

Reversine exerts cytotoxic effects through multiple cell death mechanisms in acute lymphoblastic leukemia

Carlos, J. A. E. G., Lima, K., Coelho‐Silva, J. L., Alves-Paiva, R. D. M., Moreno, N. C., Vicari, H. P., Santos, F. P. D. S., Hamerschlak, N., Costa-Lotufo, L. V., Traina, F., et al. (2020) · Cellular Oncology · doi:10.1007/s13402-020-00551-3 · Cited by 11

Evaluating and modulating TFEB in the control of autophagy: toward new treatments in CNS disorders

Costa, A. D., Metais, T., Mouthon, F., Kerkovich, D. M., & Charvériat, M. (2020) · Fundamental and Clinical Pharmacology · doi:10.1111/fcp.12634 · Cited by 12

MiR-BART2-3p targets Unc-51-like kinase 1 and inhibits cell autophagy and migration in Epstein-Barr virus-associated gastric cancer

Shi, D., Zhang, Y., Mao, T., Liu, D., Liu, W., & Luo, B. (2021) · Virus Research · doi:10.1016/j.virusres.2021.198567 · Cited by 11

Role of hypothalamic autophagy in the control of whole body energy balance

Kim, M.-S., Quan, W., & Lee, M. (2013) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-013-9257-5 · Cited by 12

Biochemical Methods to Monitor Autophagic Responses in Plants

Bao, Y., Mugume, Y., & Bassham, D. C. (2016) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2016.09.090 · Cited by 11

Starvation-induced autophagy via calcium-dependent TFEB dephosphorylation is suppressed by Shigyakusan

Ikari, S., Lu, S.-L., Hao, F., Imai, K., Araki, Y., Yamamoto, Y., Tsai, C., Nishiyama, Y., Shitan, N., Yoshimori, T., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0230156 · Cited by 11

DEF8 and Autophagy-Associated Genes Are Altered in Mild Cognitive Impairment, Probable Alzheimer’s Disease Patients, and a Transgenic Model of the Disease

Leyton, E., Matus, D., Espinoza, S., Benitez, J. M., Cortés, B. I., Gómez, W., Arévalo, N. B., Murgas, P., Manque, P., Woehlbier, U., et al. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201264 · Cited by 11

Unraveling the Janus-Faced Role of Autophagy in Hepatocellular Carcinoma: Implications for Therapeutic Interventions

Nguyen, T. H., Nguyen, T. M., Ngoc, D. T. M., You, T., Park, M. K., & Lee, C. H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216255 · Cited by 11

Regulation and Functions of Autophagy During Animal Development

Restrepo, L. J., & Baehrecke, E. H. (2024) · Journal of Molecular Biology · doi:10.1016/j.jmb.2024.168473 · Cited by 11

Role of autophagy in angiogenic potential of vascular pericytes

Milani, S. Z., Rezabakhsh, A., Karimipour, M., Salimi, L., Mardi, N., Narmi, M. T., Sadeghsoltani, F., Valioğlu, F., & Rahbarghazi‬, R. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1347857 · Cited by 10

Conserved components of the macroautophagy machinery in Caenorhabditis elegans

Zhang, H., & Meléndez, A. (2025) · Genetics · doi:10.1093/genetics/iyaf007 · Cited by 11

Epigenetic regulation and autophagy modulation debilitates insulin resistance associated Alzheimer’s disease condition in rats

Kakoty, V., Sarathlal, K. C., Dubey, S. K., Yang, C., Marathe, S. A., & Taliyan, R. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-021-00846-w · Cited by 12

Intimacy and a deadly feud: the interplay of autophagy and apoptosis mediated by amino acids

Wu, Z., Hu, C.-A. A., Wu, G., Zhaorigetu, S., Chand, H. S., Sun, K., Ji, Y. S., Wang, B., Dai, Z., Walton, B. L., et al. (2015) · Amino Acids · doi:10.1007/s00726-015-2084-0 · Cited by 10

RB1CC1 Protein Suppresses Type II Collagen Synthesis in Chondrocytes and Causes Dwarfism

Nishimura, I., Chano, T., Kita, H., Matsusue, Y., & Okabe, H. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.264192 · Cited by 10

Plasmodium berghei sporozoites in nonreplicative vacuole are eliminated by a PI3P ‐mediated autophagy‐independent pathway

Bindschedler, A., Wacker, R., Egli, J., Eickel, N., Schmuckli‐Maurer, J., Franke-Fayard, B. M. D., Janse, C. J., & Heussler, V. T. (2020) · Cellular Microbiology · doi:10.1111/cmi.13271 · Cited by 11

Metformin modulates mitochondrial autophagy in renal tubular epithelial injury induced by high glucose via the Keap1/Nrf2 pathway

Sun, D., Li, H., Du, Y., Chen, Y., Li, Y., & Wang, L. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04843-8 · Cited by 9

Evolution of innate immunity: lessons from mammalian models shaping our current view of insect immunity

Silva, R. C. M. C., Ramos, I., Travassos, L. H., Mendez, A. P. G., & Gomes, F. M. (2024) · Journal of Comparative Physiology B · doi:10.1007/s00360-024-01549-1 · Cited by 9

LC3B labeling of the parasitophorous vacuole membrane of Plasmodium berghei liver stage parasites depends on the V‐ATPase and ATG16L1

Bindschedler, A., Schmuckli‐Maurer, J., Buchser, S., Fischer, T. D., Wacker, R., Davalan, T., Brunner, J., & Heussler, V. T. (2024) · Molecular Microbiology · doi:10.1111/mmi.15259 · Cited by 11

The TOR signalling pathway in fungal phytopathogens: A target for plant disease control

Song, Y., Wang, Y., Zhang, H.-F., Saddique, M., Luo, X.-M., & Ren, M.-Z. (2024) · Molecular plant pathology · doi:10.1111/mpp.70024 · Cited by 8

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan

Tan, E. P., Lyang, N., Doroodian, S., Sanz-Martinez, P., Xu, J., Zaretski, S., Nieto-Torres, J. L., Ebata, H., Lim, S. H. Y., Hou, W. C., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2423455122 · Cited by 10

Comprehensive analysis of regulated cell death pathways: intrinsic disorder, protein–protein interactions, and cross-pathway communication

Sorokin, O., Hause, F., Wedler, A., Alakhras, T., Bauchspiess, T., Dietrich, A., Günther, W. F., Guha, C., Obika, K. B., Kraft, J., et al. (2025) · APOPTOSIS · doi:10.1007/s10495-025-02161-6 · Cited by 14

Autophagy activation attenuates the circadian clock oscillators in U2OS cells via the ATG5 pathway

Gao, D., Ma, T., Gao, L., Zhang, J., Zhang, H., Zhang, L., Dong, H., Li, Y., Zhao, L., Liu, W., et al. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110502 · Cited by 9

Progress in the mechanism of autophagy and traditional Chinese medicine herb involved in alcohol-related liver disease

Han, W., Li, H., Jiang, H., Xu, H., Lin, Y., Chen, J., Bi, C., & Liu, Z. (2023) · PeerJ · doi:10.7717/peerj.15977 · Cited by 10

WIPI β-propellers at the crossroads of autophagosome and lipid droplet dynamics

Pfisterer, S. G., Bakula, D., Cezanne, A., Robenek, H., & Proikas‐Cezanne, T. (2014) · Biochemical Society Transactions · doi:10.1042/bst20140152 · Cited by 9

Overview of Autophagy

Hayat, M. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812146-7.00001-9 · Cited by 10

An insight review of autophagy biology and neurodegenerative diseases: machinery, mechanisms and regulation

Li, S., & Le, W. (2017) · Science China Life Sciences · doi:10.1007/s11427-017-9214-7 · Cited by 9

Emerging Lysosomal Functions for Photoreceptor Cell Homeostasis and Survival

Santo, M., & Conte, I. (2021) · Cells · doi:10.3390/cells11010060 · Cited by 9

Cellular and Mitochondrial Quality Control Mechanisms in Maintaining Homeostasis in Aging

Langeh, U., Kumar, V., Kumar, A., Kumar, P., Singh, C., & Singh, A. (2022) · Rejuvenation Research · doi:10.1089/rej.2022.0027 · Cited by 9

Regulation of Autophagy by Protein Phosphorylation

Stork, B., Alers, S., Antje, S., & Wesselborg, S. (2012) · InTech eBooks · doi:10.5772/48502 · Cited by 8

Autophagy: New Questions from Recent Answers

Reggiori, F. (2012) · ISRN Molecular Biology · doi:10.5402/2012/738718 · Cited by 8

The BEACH Domain Is Critical for Blue Cheese Function in a Spatial and Epistatic Autophagy Hierarchy

Sim, J. P. L., Osborne, K. A., García, I. A., Matysik, A. S., & Kraut, R. S. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00129 · Cited by 8

Dietary Aronia melanocarpa extract enhances mTORC1 signaling, but has no effect on protein synthesis and protein breakdown-related signaling, in response to resistance exercise in rat skeletal muscle

Makanae, Y., Ato, S., Kido, K., & Fujita, S. (2019) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-019-0328-1 · Cited by 10

Atg1/ULK1 complex in autophagy process and regulation

Bhol, C. S., & Bhutia, S. K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90142-0.00003-7 · Cited by 1

The crucial role of the regulatory mechanism of the Atg1/ULK1 complex in fungi

Cai, Y., Li, L., Zhu, X., Lu, J., Liu, X., & Lin, F. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1019543 · Cited by 17

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Jung, C. H., Jun, C. B., Ro, S.-H., Kim, Y.-M., Otto, N. M., Cao, J., Kundu, M., & Kim, D.-H. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-12-1249 · Cited by 2,025

Structure and function of the ULK1 complex in autophagy

Lin, M. G., & Hurley, J. H. (2016) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2016.02.010 · Cited by 274

The mammalian ULK1 complex and autophagy initiation

Zachari, M., & Ganley, I. G. (2017) · Essays in Biochemistry · doi:10.1042/ebc20170021 · Cited by 789