The role of the Atg1/ULK1 complex in autophagy regulation

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

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Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

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ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

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ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

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Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy

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Autophagy basics

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Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway

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Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2–mediated suppression of mTORC1

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MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis

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Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach

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Targeting Drug Chemo-Resistance in Cancer Using Natural Products

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Autophagy signal transduction by ATG proteins: from hierarchies to networks

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Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide

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The WD40 Repeat PtdIns(3)P-Binding Protein EPG-6 Regulates Progression of Omegasomes to Autophagosomes

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Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis

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Autophagy Signaling Through Reactive Oxygen Species

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Autophagy

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Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation

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A small‐molecule enhancer of autophagy decreases levels of Aβ and APP‐CTF via Atg5‐dependent autophagy pathway

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Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination

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AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization

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Mitophagy and Parkinson's disease: The PINK1–parkin link

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The dual role of autophagy in cancer

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ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis

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Curcumin Ameliorates the Neurodegenerative Pathology in A53T α-synuclein Cell Model of Parkinson’s Disease Through the Downregulation of mTOR/p70S6K Signaling and the Recovery of Macroautophagy

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Structural basis of starvation-induced assembly of the autophagy initiation complex

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p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease

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Membrane dynamics in autophagosome biogenesis

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Physiological role of autophagy as an intracellular recycling system: with an emphasis on nutrient metabolism.

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Autophagy and microtubules - new story, old players

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ER stress and impaired autophagy flux in neuronal degeneration and brain injury

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ER stress, autophagy, and RNA viruses

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The Role of Autophagy in Cancer

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Autophagy in cancer development, immune evasion, and drug resistance

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Physiological consequences of heat stress in pigs

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Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy

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Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy

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FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis

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Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways

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Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy

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Autophagy: A novel mechanism of chemoresistance in cancers

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Role and regulation of autophagy in cancer

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Interactions between reactive oxygen species and autophagy

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Targeting autophagy using metallic nanoparticles: a promising strategy for cancer treatment

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A comprehensive glossary of autophagy-related molecules and processes

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Autophagy-mediated regulation of macrophages and its applications for cancer

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Regulation of Autophagy by Kinases

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Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death

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Autophagy as a therapeutic target in cardiovascular disease

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Hypoxia and aging

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The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

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ULK1 inhibits the kinase activity of mTORC1 and cell proliferation

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Cardiovascular autophagy

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Autophagy induction by trehalose: Molecular mechanisms and therapeutic impacts

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Regulation and Function of Protein Kinases and Phosphatases

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Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming

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Autophagy in colorectal cancer: An important switch from physiology to pathology

Burada, F. (2015) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v7.i11.271 · Cited by 171

The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases

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Autophagy Attenuates Noise-Induced Hearing Loss by Reducing Oxidative Stress

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Autophagy in DNA Damage Response

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The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation

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Induction of Autophagy by Palmitic Acid via Protein Kinase C-mediated Signaling Pathway Independent of mTOR (Mammalian Target of Rapamycin)

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Role and mechanisms of autophagy in acetaminophen‐induced liver injury

Chao, X., Wang, H., Jaeschke, H., & Ding, W. (2018) · Liver International · doi:10.1111/liv.13866 · Cited by 165

The Role of Autophagy in Osteoarthritis

Duan, R., Xie, H., & Liu, Z. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.608388 · Cited by 164

Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy

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Redox homeostasis, oxidative stress and mitophagy

Garza-Lombó, C., Pappa, A., Panayiotidis, M. I., & Franco, R. (2020) · Mitochondrion · doi:10.1016/j.mito.2020.01.002 · Cited by 168

The AMP-Activated Protein Kinase KIN10 Is Involved in the Regulation of Autophagy in Arabidopsis

Chen, L., Su, Z., Huang, L., Xia, F., Qi, H., Xie, L., Xiao, S., & Chen, Q. (2017) · Frontiers in Plant Science · doi:10.3389/fpls.2017.01201 · Cited by 158

Autophagy, a guardian against neurodegeneration

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Activation of mTOR: a culprit of Alzheimer’s disease?

Cai, Z., Zhou, Y., Xiao, M., Yan, L.-J., & He, W. (2015) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s75717 · Cited by 161

The elimination of accumulated and aggregated proteins: A role for aggrephagy in neurodegeneration

Yamamoto, A., & Simonsen, A. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.08.015 · Cited by 155

Autophagy hijacked through viroporin-activated calcium/calmodulin-dependent kinase kinase-β signaling is required for rotavirus replication

Crawford, S. E., Hyser, J. M., Utama, B., & Estes, M. K. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1216539109 · Cited by 158

Genetic variation in the autophagy gene ULK1 and risk of Crohnʼs disease

Henckaerts, L., Cleynen, I., Brinar, M., John, J. M., Steen, K. V., Rutgeerts, P. J., & Vermeire, S. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21486 · Cited by 164

AMBRA1 Interplay with Cullin E3 Ubiquitin Ligases Regulates Autophagy Dynamics

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AMPK → ULK1 → Autophagy

Roach, P. J. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05565-11 · Cited by 155

AMPK-Dependent Phosphorylation of ULK1 Induces Autophagy

Zhao, M., & Klionsky, D. J. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.01.009 · Cited by 161

Crosstalk between Autophagy and Apoptosis: Potential and Emerging Therapeutic Targets for Cardiac Diseases

Li, M., Gao, P., & Zhang, J. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17030332 · Cited by 156

Autophagy in kidney disease and aging: lessons from rodent models

Lenoir, O., Tharaux, P., & Huber, T. B. (2016) · Kidney International · doi:10.1016/j.kint.2016.04.014 · Cited by 156

Regulation of autophagy: Modulation of the size and number of autophagosomes

Jin, M., & Klionsky, D. J. (2014) · FEBS Letters · doi:10.1016/j.febslet.2014.06.015 · Cited by 151

Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival

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Calorie Restriction and Dietary Restriction Mimetics: A Strategy for Improving Healthy Aging and Longevity

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Cachexia in chronic obstructive pulmonary disease: new insights and therapeutic perspective

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New advances in autophagy in plants: Regulation, selectivity and function

Wang, P., Mugume, Y., & Bassham, D. C. (2017) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2017.07.018 · Cited by 150

Myristoylation confers noncanonical AMPK functions in autophagy selectivity and mitochondrial surveillance

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Autophagy in osteoarthritis

Li, Y., Zhang, F., Zeng, C., Luo, W., Xiao, W., Gao, S., & Lei, G. (2015) · Joint Bone Spine · doi:10.1016/j.jbspin.2015.06.009 · Cited by 146

Modulation of the PI3K/Akt/mTOR signaling pathway by probiotics as a fruitful target for orchestrating the immune response

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Dysfunction of autophagy in high-fat diet-induced non-alcoholic fatty liver disease

Ren, Q., Sun, Q., & Fu, J. (2023) · Autophagy · doi:10.1080/15548627.2023.2254191 · Cited by 149

p62-mediated phase separation at the intersection of the ubiquitin-proteasome system and autophagy

Danieli, A., & Martens, S. (2018) · Journal of Cell Science · doi:10.1242/jcs.214304 · Cited by 144

Dynamin-related protein 1: A protein critical for mitochondrial fission, mitophagy, and neuronal death in Parkinson’s disease

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Autophagosome formation in mammalian cells

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Connexins modulate autophagosome biogenesis

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Conversation between apoptosis and autophagy: “Is it your turn or mine?”

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Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury

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