PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling

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SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS

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Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene

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New insights into TGF-β–Smad signalling

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Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation

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Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.

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Non-Smad TGF-β signals

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Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism.

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Insulin signaling in health and disease

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Nodal Signaling in Vertebrate Development

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Cyclin-dependent kinases regulate the antiproliferative function of Smads

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Establishment of vertebrate left–right asymmetry

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E2F4/5 and p107 as Smad Cofactors Linking the TGFβ Receptor to c-myc Repression

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Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-β Receptor Activity

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Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15Ink4B transcription in response to TGF-β

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Role of Smad Proteins and Transcription Factor Sp1 in p21Waf1/Cip1 Regulation by Transforming Growth Factor-β

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Crystal Structure of a Phosphorylated Smad2

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Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways

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From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family

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GADD34–PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor

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Smad2 Nucleocytoplasmic Shuttling by Nucleoporins CAN/Nup214 and Nup153 Feeds TGFβ Signaling Complexes in the Cytoplasm and Nucleus

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Direct Interaction of c-Myc with Smad2 and Smad3 to Inhibit TGF-β-Mediated Induction of the CDK Inhibitor p15Ink4B

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Transforming Growth Factor β-Mediated Transcriptional Repression of c-myc Is Dependent on Direct Binding of Smad3 to a Novel Repressive Smad Binding Element

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Elucidation of Smad Requirement in Transforming Growth Factor-β Type I Receptor-induced Responses

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Opposed Regulation of Corepressor CtBP by SUMOylation and PDZ Binding

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Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases

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Protein serine/threonine phosphatases: life, death, and sleeping

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TGFβ signaling in health and disease

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Regulation of Plasminogen Activator Inhibitor-1 Expression by Transforming Growth Factor-β-induced Physical and Functional Interactions between Smads and Sp1

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Identification of phosphatases for Smad in the BMP/DPP pathwayPreprint

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Zebrafish Dpr2 Inhibits Mesoderm Induction by Promoting Degradation of Nodal Receptors

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Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

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Physical and Functional Interactions between Type I Transforming Growth Factor β Receptors and Bα, a WD-40 Repeat Subunit of Phosphatase 2A

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Protein Phosphatase 2Cα Dephosphorylates Axin and Activates LEF-1-dependent Transcription

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Cooperative Binding of Smad Proteins to Two Adjacent DNA Elements in the Plasminogen Activator Inhibitor-1 Promoter Mediates Transforming Growth Factor β-induced Smad-dependent Transcriptional Activation

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PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster

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Probing the Function of Conserved Residues in the Serine/Threonine Phosphatase PP2Cα

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Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-β

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Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-β and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells

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Overview of protein serine/threonine phosphatases

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Protein Phosphatase-2Cα as a Positive Regulator of Insulin Sensitivity through Direct Activation of Phosphatidylinositol 3-Kinase in 3T3-L1 Adipocytes

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TGFβ in Cancer

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Specificity, versatility, and control of TGF-β family signaling

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TGF-β Superfamily Signaling in Embryonic Development and Homeostasis

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Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

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TGF-β Family Signaling in the Control of Cell Proliferation and Survival

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