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LKB1 and SAD Kinases Define a Pathway Required for the Polarization of Cortical Neurons
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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
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“…(Neurotrace), general neuronal markers (NeuN and b-tubulin III), a dendritic marker [MAP2(a-b)], and layer-specific neuronal markers for layer 1 (reelin and Tbr1; [Hevner et al., 2001; Ogawa et al., 1995]), layer 2-4 (Cux1; [Nieto et al., 2004]) and layer 6 neurons (Tbr1; [Hevner et al., 2001]).”
Tbr1 regulates differentiation of the preplate and layer 6
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Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity
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The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity.
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UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation
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Metadata
- Authors
- Barnes, A. P., Lilley, B. N., Pan, Y. A., Plummer, L. J., Powell, A. W., Raines, A. N., Sanes, J. R., & Polleux, F.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2007-05
- Volume
- 129
- Issue
- 3
- Pages
- 549-563
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W1970302470
- Cited by
- 404
- References
- 10
- FWCI
- 11.72
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 2269 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
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