Microtubule assembly, organization and dynamics in axons and dendrites

The Molecular Motor Toolbox for Intracellular Transport

Vale, R. D. (2003) · Cell · doi:10.1016/s0092-8674(03)00111-9 · Cited by 1,982 · see citing works

Trekking across the Brain: The Journey of Neuronal Migration

Ayala, R., Shu, T., & Tsai, L.-H. (2007) · Cell · doi:10.1016/j.cell.2006.12.021 · Cited by 620 · see citing works

Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity

Shi, S.-H., Jan, L. Y., & Jan, Y.-N. (2003) · Cell · doi:10.1016/s0092-8674(02)01249-7 · Cited by 600 · see citing works

Wnt signaling in neural circuit assembly

Salinas, P. C., & Zou, Y. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125649 · Cited by 274 · see citing works

An Essential Role for Katanin in Severing Microtubules in the Neuron

Ahmad, F. J., Yu, W., McNally, F. J., & Baas, P. W. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.2.305 · Cited by 253 · see citing works

Depletion of a microtubule-associated motor protein induces the loss of dendritic identity

Yu, W., Cook, C., Sauter, C., Kuriyama, R., Kaplan, P. L., & Baas, P. W. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-15-05782.2000 · Cited by 116 · see citing works

The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos

Tuszynski, J. A., Carpenter, E. J., Huzil, J. T., Malinski, W., Luchko, T., & Luduena, R. F. (2006) · The International Journal of Developmental Biology · doi:10.1387/ijdb.052063jt · Cited by 83 · see citing works

Synaptic Energy Use and Supply

Harris, J. J., Jolivet, R., & Attwell, D. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.019 · Cited by 1,747 · see citing works

Aβ Oligomers Cause Localized Ca ²⁺ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

Zempel, H., Thies, E., Mandelkow, E., & Mandelkow, E.-M. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.2357-10.2010 · Cited by 686 · see citing works

Near-atomic model of microtubule-tau interactions

Kellogg, E. H., Hejab, N. M. A., Poepsel, S., Downing, K. H., DiMaio, F., & Nogales, E. (2018) · Science · doi:10.1126/science.aat1780 · Cited by 416 · see citing works

Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin

Zempel, H., Luedtke, J., Kumar, Y., Biernat, J., Dawson, H., Mandelkow, E., & Mandelkow, E. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.207 · Cited by 283 · see citing works

WNT signaling in neuronal maturation and synaptogenesis

Rosso, S. B., & Inestrosa, N. C. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00103 · Cited by 272 · see citing works

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

van Beuningen, S. F. B., Will, L., Harterink, M., Chazeau, A., van Battum, E. Y., Frias, C. P., Franker, M. A. M., Katrukha, E. A., Stucchi, R., Vocking, K., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.11.012 · Cited by 225 · see citing works

The Role of the Microtubule Cytoskeleton in Neurodevelopmental Disorders

Lasser, M., Tiber, J., & Lowery, L. A. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00165 · Cited by 201 · see citing works

Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment

Sohn, P. D., Tracy, T. E., Son, H.-I., Zhou, Y., Leite, R. E. P., Miller, B. L., Seeley, W. W., Grinberg, L. T., & Gan, L. (2016) · Molecular Neurodegeneration · doi:10.1186/s13024-016-0109-0 · Cited by 160 · see citing works

Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis

Schlager, M. A., Kapitein, L. C., Grigoriev, I., Burzynski, G. M., Wulf, P. S., Keijzer, N., de Graaff, E., Fukuda, M., Shepherd, I. T., Akhmanova, A., et al. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.51 · Cited by 165 · see citing works

Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis

Sohn, P. D., Huang, C. T.-L., Yan, R., Fan, L., Tracy, T. E., Camargo, C. M., Montgomery, K. M., Arhar, T., Mok, S.-A., Freilich, R., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.08.008 · Cited by 148 · see citing works

Axonal degeneration in tauopathies: disease relevance and underlying mechanisms

Kneynsberg, A., Combs, B., Christensen, K., Morfini, G., & Kanaan, N. M. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00572 · Cited by 102 · see citing works

G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer’s disease

Desale, S. E., Chidambaram, H., & Chinnathambi, S. (2021) · Molecular Biomedicine · doi:10.1186/s43556-021-00036-1 · Cited by 99 · see citing works

Mutations in AKAP5 Disrupt Dendritic Signaling Complexes and Lead to Electrophysiological and Behavioral Phenotypes in Mice

Weisenhaus, M., Allen, M. L., Yang, L., Lu, Y., Nichols, C. B., Su, T., Hell, J. W., & McKnight, G. S. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010325 · Cited by 91 · see citing works

Penrose–Hameroff orchestrated objective-reduction proposal for human consciousness is not biologically feasible

McKemmish, L. K., Reimers, J. R., McKenzie, R. H., Mark, A. E., & Hush, N. S. (2009) · Physical Review E · doi:10.1103/physreve.80.021912 · Cited by 87 · see citing works

Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia

Craddock, T. J. A., St. George, M., Freedman, H., Barakat, K. H., Damaraju, S., Hameroff, S., & Tuszynski, J. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037251 · Cited by 84 · see citing works

Tau can switch microtubule network organizations: from random networks to dynamic and stable bundles

Prezel, E., Elie, A., Delaroche, J., Stoppin-Mellet, V., Bosc, C., Serre, L., Fourest-Lieuvin, A., Andrieux, A., Vantard, M., & Arnal, I. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e17-06-0429 · Cited by 83 · see citing works

Retinal ganglion cell dendrite pathology and synapse loss

Agostinone, J., & Di Polo, A. (2015) · Progress in Brain Research · doi:10.1016/bs.pbr.2015.04.012 · Cited by 68 · see citing works

A Structural Ensemble of a Tau-Microtubule Complex Reveals Regulatory Tau Phosphorylation and Acetylation Mechanisms

Brotzakis, Z. F., Lindstedt, P. R., Taylor, R. J., Rinauro, D. J., Gallagher, N. C. T., Bernardes, G. J. L., & Vendruscolo, M. (2021) · ACS Central Science · doi:10.1021/acscentsci.1c00585 · Cited by 70 · see citing works

Adaptors for disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer’s disease

Beck, T. N., Nicolas, E., Kopp, M. C., & Golemis, E. A. (2014) · Oncoscience · doi:10.18632/oncoscience.64 · Cited by 50 · see citing works

Neuropathophysiology of lysosomal storage diseases: synaptic dysfunction as a starting point for disease progression

Pará, C., Bose, P., & Pshezhetsky, A. V. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9030616 · Cited by 49 · see citing works

Phylogenetic Analysis Supports a Link between DUF1220 Domain Number and Primate Brain Expansion

Zimmer, F., & Montgomery, S. H. (2015) · Genome Biology and Evolution · doi:10.1093/gbe/evv122 · Cited by 36 · see citing works

Rare genetic variants confer a high risk of ADHD and implicate neuronal biology

Demontis, D., Duan, J., Hsu, Y.-H. H., Pintacuda, G., Grove, J., Nielsen, T. T., Thirstrup, J., Martorana, M., Botts, T., Satterstrom, F. K., et al. (2026) · Nature · doi:10.1038/s41586-025-09702-8 · Cited by 17 · see citing works

Microtubule Cytoskeletal Network Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders

Gąssowska-Dobrowolska, M., Czapski, G. A., Cieślik, M., Zajdel, K., Frontczak-Baniewicz, M., Babiec, L., & Adamczyk, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087303 · Cited by 10 · see citing works

Ghost Neuron preparation unlocks high-resolution structural mapping of intracellular architecture in axons

Bodakuntla, S., Marelli, J., Vasquez-Montes, V., Glauser, S., Biertümpfel, C., & Mizuno, N. (2026) · Nature Communications · doi:10.1038/s41467-026-77741-4