The DOI matches its Crossref record; 127 of the 127 references it cites were found in a registry or an index.
Anti-inflammatory Agents: Present and Future
Open accessAbstract
Inflammation involving the innate and adaptive immune systems is a normal response to infection. However, when allowed to continue unchecked, inflammation may result in autoimmune or autoinflammatory disorders, neurodegenerative disease, or cancer. A variety of safe and effective anti-inflammatory agents are available, including aspirin and other nonsteroidal anti-inflammatories, with many more drugs under development. In particular, the new era of anti-inflammatory agents includes "biologicals" such as anticytokine therapies and small molecules that block the activity of kinases. Other anti-inflammatories currently in use or under development include statins, histone deacetylase inhibitors, PPAR agonists, and small RNAs. This Review discusses the current status of anti-inflammatory drug research and the development of new anti-inflammatory therapeutics.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Inflammation, as a basic pathological process, is critically implicated in the pathogenesis and progression of numerous diseases.”
From Picroside II as a Potential Anti-Inflammatory Agent (2026) · cites this paper as [3]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
Ridker, P. M., Danielson, E., Fonseca, F. A. H., Genest, J., Gotto, A. M., Kastelein, J. J. P., Koenig, W., Libby, P., Lorenzatti, A. J., MacFadyen, J. G., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0807646 · Cited by 6,674
Biologic basis for interleukin-1 in disease.
Dinarello, C. (1996) · Blood · doi:10.1182/blood.v87.6.2095.bloodjournal8762095 · Cited by 4,344
Self-citationRosuvastatin to Prevent Vascular Events in Men and Women With Elevated C-Reactive Protein
Ridker, P. M., Danielson, E., Fonseca, F. A. H., Genest, J. J., Gotto, A. M., Kastelein, J. J. P., Köenig, W., Libby, P., Lorenzatti, A. J., MacFadyen, J. G., et al. (2009) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000344393.60303.0a · Cited by 3,641
Immunological and inflammatory functions of the interleukin-1 family
Dinarello, C. A. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132612 · Cited by 3,466
Self-citationThioredoxin-interacting protein links oxidative stress to inflammasome activation
Zhou, R., Tardivel, A., Thorens, B., Choi, I., & Tschopp, J. (2010) · Nature Immunology · doi:10.1038/ni.1831 · Cited by 2,708
The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina
Liuzzo, G., Biasucci, L. M., Gallimore, J. R., Grillo, R. L., Rebuzzi, A. G., Pepys, M. B., & Maseri, A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408183310701 · Cited by 2,354
Endres, S., Ghorbani, R., Kelley, V. E., Georgilis, K., Lonnemann, G., van der Meer, J. W. M., Cannon, J. G., Rogers, T. S., Klempner, M. S., Weber, P. C., et al. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902023200501 · Cited by 1,911
Self-citationHistone deacetylases and cancer: causes and therapies
Marks, P. A., Rifkind, R. A., Richon, V. M., Breslow, R., Miller, T., & Kelly, W. K. (2001) · Nature reviews. Cancer · doi:10.1038/35106079 · Cited by 1,866
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
Larsen, C. M., Faulenbach, M., Vaag, A., Vølund, A., Ehses, J. A., Seifert, B., Mandrup-Poulsen, T., & Donath, M. Y. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa065213 · Cited by 1,798
Hoffman, H. M., Mueller, J. L., Broide, D. H., Wanderer, A. A., & Kolodner, R. D. (2001) · Nature Genetics · doi:10.1038/ng756 · Cited by 1,679
Research works printed but not linked: 1
- Donath, 2009, XOMA 052, a potential disease modifying anti-1L-1beta antibody, shows sustained HbA1c reductions 3 months after a single injection with no increases in safety parameters in subjects with type 2 diabetes, Diabetes, 58, A30
Cited by
Sorted by citations
Items 301–400 of 999
Hassan, A. H. E., Yoo, S. Y., Lee, K. W., Yoon, Y. M., Ryu, H. W., Jeong, Y., Shin, J., Kang, S., Kim, S.-Y., Lee, H., et al. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.07.030 · Cited by 44
Control of inflammation using non-invasive neuromodulation: past, present and promise
Tynan, A., Brines, M. L., & Chavan, S. S. (2021) · International Immunology · doi:10.1093/intimm/dxab073 · Cited by 45
Direct Inhibition of Human RANK+ Osteoclast Precursors Identifies a Homeostatic Function of IL-1β
Lee, B., Kim, T., Jun, J., Yoo, D., Woo, J.-H., Choi, S. J., Lee, Y. H., Song, G. G., Sohn, J., Park‐Min, K., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001591 · Cited by 45
Transition Metal‐Based Therapies for Inflammatory Diseases
Song, Y., You, Q., & Chen, X. S. (2023) · Advanced Materials · doi:10.1002/adma.202212102 · Cited by 47
Wang, Y., Zhao, G.-X., Xu, L., Liu, K., Pan, H., He, J., Cai, J., Ouyang, D., & He, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089751 · Cited by 43
Ridker, P. M. (2018) · Journal of Internal Medicine · doi:10.1111/joim.12862 · Cited by 43
Debnath, U., Mukherjee, S., Joardar, N., Babu, S. P. S., Jana, K., & Misra, A. K. (2019) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2019.04.016 · Cited by 43
Sousa, C., Leitão, A. J., Neves, B. M., Judas, F., Cavaleiro, C., & Mendes, A. F. (2020) · Scientific Reports · doi:10.1038/s41598-020-64032-1 · Cited by 43
Bedi, P., Chalmers, J. D., Graham, C., Clarke, A., Donaldson, S., Doherty, C. J., Govan, J. R. W., Davidson, D. J., Rossi, A. G., & Hill, A. T. (2017) · CHEST Journal · doi:10.1016/j.chest.2017.05.017 · Cited by 42
Alam, A., Ali, M., Rehman, N. U., Latif, A., Shah, A. J., Wazir, N. U., Lodhi, M. A., Kamal, M., Ayaz, M., Al‐Harrasi, A., et al. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.12.259 · Cited by 42
Hot under the clot: venous thrombogenesis is an inflammatory process
Rayes, J., & Brill, A. G. (2024) · Blood · doi:10.1182/blood.2023022522 · Cited by 44
In Search of Magic Bullets: The Golden Age of Immunotherapeutics
O’Shea, J. J., Kanno, Y., & Chan, A. C. (2014) · Cell · doi:10.1016/j.cell.2014.03.010 · Cited by 44
Klafke, J. Z., Pereira, R. L. D., Hirsch, G. E., Parisi, M. M., Porto, F. G., de Almeida, A. S., Rubin, F. H., Schmidt, A. C., Beutler, H., Nascimento, S., et al. (2015) · Phytomedicine · doi:10.1016/j.phymed.2015.11.010 · Cited by 44
Laksmıtawatı, D. R., Prasanti, A. P., Larasinta, N., Syauta, G. A., Hilda, R., Ramadaniati, H. U., Widyastuti, A., Karami, N., Afni, M., Rihibiha, D. D., et al. (2016) · Journal of Natural Remedies · doi:10.18311/jnr/2016/5367 · Cited by 42
Stimuli-responsive and biomimetic delivery systems for sepsis and related complications
Ismail, E. A., Devnarain, N., Govender, T., & Omolo, C. A. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.11.013 · Cited by 41
Abdelhamid, H. N., & Wu, H. (2014) · RSC Advances · doi:10.1039/c4ra07638a · Cited by 41
Yuan, H.-L., Zhao, Y.-L., Ding, C.-F., Zhu, P.-F., Jin, Q., Liu, Y.-P., Ding, Z.-T., & Luo, X.-D. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.112935 · Cited by 44
Xu, Y. F., Liu, J., Zeng, Y., Jin, S., Liu, W., Li, Z., Qin, X., & Bai, Y. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114671 · Cited by 40
Limonoids with anti-inflammatory activity: A review
Hilmayanti, E., Nurlelasari, N., Supratman, U., Kabayama, K., Shimoyama, A., & Fukase, K. (2022) · Phytochemistry · doi:10.1016/j.phytochem.2022.113469 · Cited by 40
Huang, J., Hong, X., Chen, S., He, Y., Xie, L., Gao, F., Zhu, C., Jin, X., Yan, H., Ye, Y., et al. (2024) · Advanced Science · doi:10.1002/advs.202402473 · Cited by 40
Hedl, M., & Abraham, C. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.08.048 · Cited by 40
Innate and adaptive immune response in stroke: Focus on epigenetic regulation
Picascia, A., Grimaldi, V., Iannone, C., Soricelli, A., & Claudio Napoli, A. (2015) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2015.10.013 · Cited by 40
Ye, S., Liu, Q., Huang, K., Jiang, X., & Zhang, X. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2021.113059 · Cited by 39
Nie, Q., Li, C., Wang, Y., Hu, Y., Pu, W., Zhang, Q., Cai, J., Lin, Y., Li, G., Wang, C., et al. (2022) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.07.013 · Cited by 39
Nanomaterials for Delivering Antibiotics in the Therapy of Pneumonia
Tang, J., Ouyang, Q., Li, Y., Zhang, P., Jin, W., Qu, S., Yang, F., He, Z., & Qin, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415738 · Cited by 39
Repurposing Fenamic Acid Drugs To Combat Multidrug-Resistant Neisseria gonorrhoeae
Seong, Y. J., Alhashimi, M., Mayhoub, A. S., Mohammad, H. T., & Seleem, M. N. (2020) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02206-19 · Cited by 40
Yeisley, D. J., Arabiyat, A. S., & Hahn, M. S. (2021) · Cannabis and Cannabinoid Research · doi:10.1089/can.2020.0109 · Cited by 41
Zhang, M., Ma, X., Xu, H., Wu, W., He, X., Wang, X., Jiang, M., Hou, Y., & Bai, G. (2019) · FEBS Journal · doi:10.1111/febs.15112 · Cited by 38
Antinociception induced by atorvastatin in different pain models
García, G. G., Miranda, H. F., Noriega, V., Sierralta, F., Olavarría, L., Zepeda, R. J., & Prieto, J. C. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.08.007 · Cited by 38
Pharmacokinetic/Pharmacodynamic Modeling in Inflammation
Lon, H., Liu, D., & Jusko, W. J. (2012) · Critical Reviews in Biomedical Engineering · doi:10.1615/critrevbiomedeng.v40.i4.50 · Cited by 38
Micro- and nano-plastics induce inflammation and cell death in human cells
Bishop, B., Webber, W. S., Atif, S. M., Ley, A., Pankratz, K. A., Kostelecky, R. E., Colgan, S. P., Dinarello, C. A., Zhang, W., & Li, S. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1528502 · Cited by 39
Self-citationKong, P., Wu, R., Liu, X., Liu, J., Chen, S., Ye, M., Yang, C., Song, Z., He, W., Yin, C., et al. (2016) · Journal of Cancer · doi:10.7150/jca.16524 · Cited by 37
Srivastava, P., Singh, K., Verma, M., Sivakumar, S., & Patra, A. K. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.12.025 · Cited by 37
Wang, W., Wu, Y., Yang, K., Wu, C., Tang, R., Li, H., & Chen, L. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.04.022 · Cited by 37
Applications and Mechanisms of Stimuli-Responsive Hydrogels in Traumatic Brain Injury
Li, X., Duan, L., Kong, M., Wen, X., Guan, F., & Ma, S. (2022) · Gels · doi:10.3390/gels8080482 · Cited by 39
Niu, P., Wu, Y., Zeng, F., Zhang, S., Liu, S., & Gao, H. (2023) · NPG Asia Materials · doi:10.1038/s41427-023-00478-9 · Cited by 36
Wang, P., Xia, Q., Zhang, Y., Cao, D., & Zheng, X. (2024) · Respiratory Research · doi:10.1186/s12931-023-02637-6 · Cited by 36
Glowacki, A. J., Gottardi, R., Yoshizawa, S., Cavalla, F., Garlet, G. P., Sfeir, C. S., & Little, S. R. (2014) · Annals of Biomedical Engineering · doi:10.1007/s10439-014-1125-2 · Cited by 36
Klegeris, A., Madeira, J., & Schindler, S. M. (2015) · Neural Regeneration Research · doi:10.4103/1673-5374.153686 · Cited by 36
Hsieh, L. T.-H., Nastase, M.-V., Roedig, H., Zeng-Brouwers, J., Poluzzi, C., Schwalm, S. A., Fork, C., Tredup, C., Brandes, R. P., Wygrecka, M., et al. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18030595 · Cited by 36
Molecular docking analysis of curcumin analogues with COX-2
Sohilait, M. R., Pranowo, H. D., & Haryadi, W. (2017) · Bioinformation · doi:10.6026/97320630013356 · Cited by 36
Imamiya, R., Shinohara, A., Yakura, D., Yamaguchi, T., Ueda, K., Oguro, A., Minamiyama, Y., Ichikawa, H., Horiguchi, Y., & Osada‐Oka, M. (2023) · mBio · doi:10.1128/mbio.03051-22 · Cited by 38
Epigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells
Dunoyer-Geindre, S., & Kruithof, E. K. O. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvr028 · Cited by 37
Yield Loss in Soybean Caused by Heterodera glycines.
Young, L. D. (1996) · PubMed Central · Cited by 36
Tao, H., Liu, X., Tian, R., Liu, Y., Zeng, Y., Meng, X., & Zhang, Y. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115726 · Cited by 34
Zhen, M., Xu, Y. M., Wang, C., & Bai, C. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202409319 · Cited by 36
Anti-inflammatory activity of methyl ferulate isolated from Stemona tuberosa Lour
Phuong, N. T. M., Cuong, T. T., & Quang, Đ. N. (2014) · Asian Pacific Journal of Tropical Medicine · doi:10.1016/s1995-7645(14)60254-6 · Cited by 35
Sandhiutami, N. M. D., Moordiani, M., Laksmıtawatı, D. R., Fauziah, N., Maesaroh, M., & Widowati, W. (2017) · Europe PMC (PubMed Central) · doi:10.22038/ijbms.2017.8102 · Cited by 35
Caillot, A. R. C., Bezerra, I. D. L., Palhares, L. C. G. F., Santana-Filho, A. P., Chavante, S. F., & Sassaki, G. L. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.02.122 · Cited by 37
Silva, I., Alípio, C., Pinto, R. M. A., & Mateus, V. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111558 · Cited by 39
Xu, Z. Q., Gao, Z., Lu, J., Wang, T., Wang, W., Fan, L., Xi, J., & Han, B. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112977 · Cited by 35
Disruption of neurogenesis by hypothalamic inflammation in obesity or aging
Purkayastha, S., & Cai, D. (2013) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-013-9279-z · Cited by 36
Patra, S., Sundaram, M., Meenu, M., Priya, P., & Pemaiah, B. (2016) · International Immunopharmacology · doi:10.1016/j.intimp.2016.02.027 · Cited by 36
Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer’s Disease
Cacciatore, I., Marinelli, L., Fornasari, E., Cerasa, L. S., Eusepi, P., Türkez, H., Pomilio, C., Reale, M., D’Angelo, C., Costantini, E., et al. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17071035 · Cited by 35
Liu, S., Wang, W., Chen, Z., Wu, P., Pu, W., Li, G., Song, J., & Zhang, J. (2024) · Advanced Science · doi:10.1002/advs.202401882 · Cited by 33
Design, synthesis, and biological evaluation of a biyouyanagin compound library
Nicolaou, K. C., Sanchini, S., Šarlah, D., Lu, G., Wu, T., Nomura, D. K., Cravatt, B. F., Cubitt, B., de la Torre, J. C., Hessell, A. J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015258108 · Cited by 34
Laksmıtawatı, D. R., Widyastuti, A., Karami, N., Afifah, E., Rihibiha, D. D., Nufus, H., & Widowati, W. (2017) · Bangladesh Journal of Pharmacology · doi:10.3329/bjp.v12i1.28714 · Cited by 34
Sieniawska, E., Michel, P., Mroczek, T., Granica, S., & Skalicka‐Woźniak, K. (2019) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.12.057 · Cited by 34
Widowati, W., Prahastuti, S., Ekayanti, N. L. W., Munshy, U. Z., Kusuma, H. S. W., Wibowo, S. H. B., Amalia, A., Widodo, W. S., & Rizal, R. (2019) · Journal of Physics Conference Series · doi:10.1088/1742-6596/1374/1/012052 · Cited by 34
Anderson, A. M. L., Jang, J. H., Easley, K. A., Fuchs, D., Gisslén, M., Zetterberg, H., Blennow, K., Ellis, R. J., Franklin, D., Heaton, R. K., et al. (2020) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000002484 · Cited by 34
Liu, X., Liu, M., Lee, L., Davies, M., Wang, Z., Kim, H., & Feeley, B. T. (2020) · Journal of Orthopaedic Research® · doi:10.1002/jor.24865 · Cited by 34
Syed, N., Singh, S. B., Chaturvedi, S., Nannaware, A. D., Khare, S. K., & Rout, P. K. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2068124 · Cited by 33
Liu, S., Wang, W., Wu, P., Chen, Z., Pu, W., Li, L., Li, G., Zhang, J., & Song, J. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202301523 · Cited by 33
Freymann, E., Carvalho, S., Garbe, L., Ghazhelia, D. D., Hobaiter, C., Huffman, M. A., Muhumuza, G., Schulz, L., Sempebwa, D., Wald, F., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0305219 · Cited by 33
Targeted delivery systems for biological therapies of inflammatory diseases
Tran, T.-H., & Amiji, M. M. (2014) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2015.972931 · Cited by 34
Zhang, L. J., Shi, L., Soars, S. M., Kamps, J. T., & Yin, H. H. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b01557 · Cited by 33
Polymer-Drug Conjugates in Inflammation Treatment
KOZIOLOVÁ, E., Venclíková, K., & Etrych, T. (2018) · Physiological Research · doi:10.33549/physiolres.933977 · Cited by 33
Stazio, M. D., Foschi, N., Athanasakis, E., Gasparini, P., & D’Adamo, P. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247603 · Cited by 33
Chandan, G., Kumar, C., Chibber, P., Kumar, A., Singh, G., Satti, N. K., Gulilat, H., Saini, A. K., Bishayee, A., & Saini, R. V. (2021) · Phytomedicine · doi:10.1016/j.phymed.2021.153621 · Cited by 34
Xu, S., Liao, Y., Wang, Q., Liu, L., & Yang, W. F. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2049691 · Cited by 33
Statin and Aspirin Use and the Risk of Mood Disorders among Men
Williams, L. J., Pasco, J. A., Mohebbi, M., Jacka, F. N., Stuart, A. L., Venugopal, K., O’Neil, A., & Berk, M. (2016) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyw008 · Cited by 32
Bhat, M. A., Al-Omar, M. A., Ansari, M. A., Zoheir, K. M. A., Imam, F., Attia, S. M., Bakheet, S. A., Nadeem, A., Korashy, H. M., Voronkov, A. A., et al. (2015) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b00934 · Cited by 32
Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies
Clement, M., Pearson, J. A., Gras, S., van den Berg, H. A., Lissina, A., Llewellyn‐Lacey, S., Willis, M., Dockree, T., McLaren, J. E., Makinde, J., et al. (2016) · Scientific Reports · doi:10.1038/srep35332 · Cited by 32
Laugel, B., Cole, D. K., Clement, M., Wooldridge, L., Price, D. A., & Sewell, A. K. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0611316 · Cited by 32
Histone Deacetylase Inhibitors: Updated Studies in Various Epigenetic-Related Diseases
Zwergel, C., Stazi, G., Valente, S., & Mai, A. (2016) · Journal of Clinical Epigenetics · Cited by 32
A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation
Ralvenius, W. T., Mungenast, A. E., Woolf, H., Huston, M. M., Gillingham, T. Z., Godin, S. K., Penney, J., Cam, H. P., Gao, F., Fernandez, C. G., et al. (2023) · Journal of Experimental Medicine · doi:10.1084/jem.20222105 · Cited by 29
“Glucocorticoid receptor agonists that block the production of proinflammatory prostaglandins and leukotrienes are an alternative anti-inflammatory treatment (Dinarello, 2010).”
InfluentialHou, Y., Wu, R., Zhou, Y. F., Yin, C., Gai, Y., Jiang, D., Wang, K., & Xia, X. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03921-x · Cited by 43
Sekhon-Loodu, S., Ziaullah, Z., Rupasinghe, H. P. V., Wang, Y., Kulka, M., & Shahidi, F. (2015) · Inflammopharmacology · doi:10.1007/s10787-015-0237-0 · Cited by 32
Ladero-Auñon, I., Molina, E., Holder, A. L., Kolakowski, J., Harris, H., Urkitza, A., Anguíta, J., Werling, D., & Elguezábal, N. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.645304 · Cited by 31
Anti-inflammatory and analgesic actions of bufotenine through inhibiting lipid metabolism pathway
Wang, J., Xu, D., Shen, L., Zhou, J., Lv, X., Ma, H., Li, N., Wu, Q., & Duan, J. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111749 · Cited by 31
Renner, S. W., Qiao, Y., Gmelin, T. A., Santanasto, A. J., Boudreau, R. M., Walston, J. D., Perls, T. T., Christensen, K., Newman, A. B., & Glynn, N. W. (2021) · Aging Clinical and Experimental Research · doi:10.1007/s40520-021-01923-x · Cited by 33
Statins inhibit T-acute lymphoblastic leukemia cell adhesion and migration through Rap1b
Infante, E., Heasman, S. J., & Ridley, A. J. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0810441 · Cited by 31
Pan, L., Hang, N., Zhang, C., Chen, Y., Li, S., Sun, Y., Li, Z., & Meng, X. (2017) · Molecules · doi:10.3390/molecules22020213 · Cited by 31
miRNAs in Drug Response Variability: Potential Utility as Biomarkers for Personalized Medicine
Latini, A., Borgiani, P., Novelli, G., & Ciccacci, C. (2019) · Pharmacogenomics · doi:10.2217/pgs-2019-0089 · Cited by 33
Lawsone Unleashed: A Comprehensive Review on Chemistry, Biosynthesis, and Therapeutic Potentials
Nair, A. S., Sekar, M., Gan, S. H., Kumarasamy, V., Subramaniyan, V., Wu, Y. S., Rani, N. N. I. M., Ravi, S., & Wong, L. S. (2024) · Drug Design Development and Therapy · doi:10.2147/dddt.s463545 · Cited by 30
Zheng, W., Li, Y., Wang, Y., He, J., Zhao, Q., & Huang, A. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.142451 · Cited by 30
Liddo, R. D., Valente, S., Taurone, S., Zwergel, C., Marrocco, B., Turchetta, R., Conconi, M. T., Scarpa, C., Bertalot, T., Schrenk, S., et al. (2016) · Autoimmunity · doi:10.3109/08916934.2015.1134510 · Cited by 31
Oh, M., Choi, H., Ha, S. K., Choi, I., & Park, H.-Y. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.01.172 · Cited by 30
de Anda‐Jáuregui, G., Guo, K., McGregor, B. A., & Hur, J. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00151 · Cited by 30
Ecovio®-based nanofibers as a potential fast transdermal releaser of aceclofenac
Carvalho, B. M., Pellá, M. C. G., Hardt, J. C., Rossin, A. R. D. S., Tonet, A., Ilipronti, T., Caetano, J., & Dragunski, D. C. (2020) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2020.115206 · Cited by 30
Han, C., Liu, Y., Tian, X., Röminger, F., & Hashmi, A. S. K. (2021) · Organic Letters · doi:10.1021/acs.orglett.1c03667 · Cited by 30
Nasir, N. N., Sekar, M., Fuloria, S., Gan, S. H., Rani, N. N. I. M., Ravi, S., Begum, M. Y., Chidambaram, K., Sathasivam, K. V., Jeyabalan, S., et al. (2022) · Molecules · doi:10.3390/molecules27030734 · Cited by 31
Herman, A. P., Krawczyńska, A., Bochenek, J., Antushevich, H., Herman, A., & Tomaszewska-Zaremba, D. (2014) · BioMed Research International · doi:10.1155/2014/475152 · Cited by 30
Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential
Fonseca‐Barahona, I., Shahbaz, K., & Baroutian, S. (2025) · ChemBioEng Reviews · doi:10.1002/cben.70007 · Cited by 35
Purinergic signaling during Porphyromonas gingivalis infection
Almeida-da-Silva, C. L. C., Morandini, A. C., Ulrich, H., Ojcius, D. M., & Coutinho‐Silva, R. (2016) · Biomedical Journal · doi:10.1016/j.bj.2016.08.003 · Cited by 29
Tian, Y., Liu, Y., Xue, C., Wang, J., Wang, Y., Xu, J., & Li, Z. (2020) · Food & Function · doi:10.1039/d0fo00804d · Cited by 29
Slade, C. D., Reagin, K. L., Lakshmanan, H. G., Klonowski, K. D., & Watford, W. T. (2020) · PLoS ONE · doi:10.1371/journal.pone.0235706 · Cited by 29
Anti-Inflammatory Polymeric Nanoparticles Based on Ketoprofen and Dexamethasone
Espinosa‐Cano, E., Aguilar, M. R., Portilla, Y., Barber, D. F., & Román, J. S. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12080723 · Cited by 29
Advances in the role and mechanism of miRNA in inflammatory pain
Zhang, X., Zhu, L., Wang, X., Xia, L., & Zhang, Y. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114463 · Cited by 31
Shi, Z., Qian, X., Liu, C., Han, L., Zhang, K., Chen, L., Zhang, J., Pu, P., Yuan, X., Kang, C., et al. (2012) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12041 · Cited by 29
Metadata
- Authors
- Dinarello, C. A.
- Affiliations
- Radboud University Nijmegen (NL)
- Corresponding author
- Dinarello, Charles A.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 140
- Issue
- 6
- Pages
- 935-950
- ISSN
- 0092-8674 (ISSN-L)
- PMC
- PMC3752337
- OpenAlex
- W2126894693
- Cited by
- 1,095
- References
- 127
- Citations by year
- 2026: 50 · 2025: 92 · 2024: 97 · 2023: 79 · 2022: 79 · 2021: 90 · 2020: 73 · 2019: 63 · 2018: 64 · 2017: 62 · 2016: 60 · 2015: 64 · 2014: 51 · 2013: 48 · 2012: 51
- FWCI
- 6.09
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Funders
- National Cancer Institute (CA 6934)
- National Institute of Allergy and Infectious Diseases (AI‑15614, R56AI015614, R01AI015614)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Inflammatory mediators and NSAID effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › NF-κB Signaling Pathways
- Health Sciences › Medicine › Complementary and alternative medicine › Natural Compounds in Disease Treatment
- Keywords
- anti-inflammatory agents, inflammation, autoimmune disease, autoinflammatory disease, neurodegenerative diseases, cancer, aspirin, nonsteroidal anti-inflammatory drugs, biologicals, anti-cytokine therapy, kinase inhibitors, statins, histone deacetylase inhibitors, PPAR agonists, small RNA, drug development
- MeSH terms
- Animals, Anti-Inflammatory Agents, Autoimmune Diseases, Humans, Inflammation, Drug Design
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review