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DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer
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“Although all transcriptionally active forms of the mammalian p53 protein family are tetrameric (Luh et al. 2013), TAp63a in oocytes forms inactive dimers (Fig. 3B) (Deutsch et al. 2011).”
From Structural Evolution and Dynamics of the p53 Proteins (2017) · cites this paper as Deutsch et al. 2011
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Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain
Kussie, P. H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A. J., & Pavletich, N. P. (1996) · Science · doi:10.1126/science.274.5289.948 · Cited by 2,206
p53 ubiquitination: Mdm2 and beyond
Brooks, C. L., & Gu, W. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.01.020 · Cited by 924
p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia
Senoo, M., Pinto, F., Crum, C. P., & McKeon, F. (2007) · Cell · doi:10.1016/j.cell.2007.02.045 · Cited by 881 · cited 2×
“development of stratified epithelial tissues including skin by maintaining a stem cell population in the basal layer (Senoo et al., 2007).”
BackgroundSelf-citationPRIMA-1 reactivates mutant p53 by covalent binding to the core domain
Lambert, J. M. R., Gorzov, P., Veprintsev, D. B., Söderqvist, M., Segerbäck, D., Bergman, J., Fersht, A. R., Hainaut, P., Wiman, K. G., & Bykov, V. J. N. (2009) · Cancer Cell · doi:10.1016/j.ccr.2009.03.003 · Cited by 592
The p53 orchestra: Mdm2 and Mdmx set the tone
Wade, M., Wang, Y. V., & Wahl, G. M. (2010) · Trends in Cell Biology · doi:10.1016/j.tcb.2010.01.009 · Cited by 450
Research works printed but not linked: 39
- Brandt, 2009, Conservation of DNA-binding specificity and oligomerisation properties within the p53 family, BMC Genomics, 10, 628, 10.1186/1471-2164-10-628 · DOI · Paper page
- Burge, 2009, Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation, Proc. Natl. Acad. Sci. USA, 106, 3142, 10.1073/pnas.0900383106 · DOI
- Celli, 1999, Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome, Cell, 99, 143, 10.1016/S0092-8674(00)81646-3 · DOI · Paper page
- Chan, 2004, How many mutant p53 molecules are needed to inactivate a tetramer?, Mol. Cell. Biol., 24, 3536, 10.1128/MCB.24.8.3536-3551.2004 · DOI · Paper page
- Chene, 2001, The role of tetramerization in p53 function, Oncogene, 20, 2611, 10.1038/sj.onc.1204373 · DOI · Paper page
- Cole, 2004, Analysis of heterogeneous interactions, Methods Enzymol., 384, 212, 10.1016/S0076-6879(04)84013-8 · DOI
- Coutandin, 2009, Conformational stability and activity of p73 require a second helix in the tetramerization domain, Cell Death Differ., 16, 1582, 10.1038/cdd.2009.139 · DOI
- Coutandin, 2010, Tracing the protectors path from the germ line to the genome, Proc. Natl. Acad. Sci. USA, 107, 15318, 10.1073/pnas.1001069107 · DOI
- Davison, 2001, Structure and functionality of a designed p53 dimer, J. Mol. Biol., 307, 605, 10.1006/jmbi.2001.4450 · DOI
- De Laurenzi, 1999, Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants epsilon and zeta, Cell Death Differ., 6, 389, 10.1038/sj.cdd.4400521 · DOI
- Derry, 2001, Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance, Science, 294, 591, 10.1126/science.1065486 · DOI · Paper page
- Guo, 2009, TAp63 induces senescence and suppresses tumorigenesis in vivo, Nat. Cell Biol., 11, 1451, 10.1038/ncb1988 · DOI
- Hoffmann, 2009, Probing the limits of liquid droplet laser desorption mass spectrometry in the analysis of oligonucleotides and nucleic acids, Rapid Commun. Mass Spectrom., 23, 2176, 10.1002/rcm.4129 · doi:10.1002/rcm.4129
- Horikoshi, 1995, Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression, Mol. Cell. Biol., 15, 227, 10.1128/MCB.15.1.227 · DOI · Paper page
- Jeffrey, 1995, Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms, Science, 267, 1498, 10.1126/science.7878469 · DOI · Paper page
- Joerger, 2009, Structural evolution of p53, p63, and p73: implication for heterotetramer formation, Proc. Natl. Acad. Sci. USA, 106, 17705, 10.1073/pnas.0905867106 · DOI
- Kaghad, 1997, Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers, Cell, 90, 809, 10.1016/S0092-8674(00)80540-1 · DOI · Paper page
- Lebowitz, 2002, Modern analytical ultracentrifugation in protein science: a tutorial review, Protein Sci., 11, 2067, 10.1110/ps.0207702 · DOI · Paper page
- Lee, 1994, Solution structure of the tetrameric minimum transforming domain of p53, Nat. Struct. Biol., 1, 877, 10.1038/nsb1294-877 · DOI · Paper page
- Lu, 1995, Human TAFII31 protein is a transcriptional coactivator of the p53 protein, Proc. Natl. Acad. Sci. USA, 92, 5154, 10.1073/pnas.92.11.5154 · DOI · Paper page
- McGrath, 2001, Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63, Hum. Mol. Genet., 10, 221, 10.1093/hmg/10.3.221 · DOI · Paper page
- Mills, 1999, p63 is a p53 homologue required for limb and epidermal morphogenesis, Nature, 398, 708, 10.1038/19531 · DOI · Paper page
- Morgner, 2007, A novel approach to analyze membrane proteins by laser mass spectrometry: from protein subunits to the integral complex, J. Am. Soc. Mass Spectrom., 18, 1429, 10.1016/j.jasms.2007.04.013 · DOI
- Ortt, 2006, Derivation of the consensus DNA-binding sequence for p63 reveals unique requirements that are distinct from p53, FEBS Lett., 580, 4544, 10.1016/j.febslet.2006.07.004 · DOI
- Ou, 2007, Structural evolution of C-terminal domains in the p53 family, EMBO J., 26, 3463, 10.1038/sj.emboj.7601764 · DOI
- Pearson, 2010, A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages, Development, 137, 213, 10.1242/dev.044297 · DOI · Paper page
- Rossi, 2006, The E3 ubiquitin ligase Itch controls the protein stability of p63, Proc. Natl. Acad. Sci. USA, 103, 12753, 10.1073/pnas.0603449103 · DOI · Paper page
- Schleiff, 2003, A GTP-driven motor moves proteins across the outer envelope of chloroplasts, Proc. Natl. Acad. Sci. USA, 100, 4604, 10.1073/pnas.0730860100 · DOI
- Schmale, 1997, A novel protein with strong homology to the tumor suppressor p53, Oncogene, 15, 1363, 10.1038/sj.onc.1201500 · DOI · Paper page
- Senoo, 1998, A second p53-related protein, p73L, with high homology to p73, Biochem. Biophys. Res. Commun., 248, 603, 10.1006/bbrc.1998.9013 · DOI
- Serber, 2002, A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism, Mol. Cell. Biol., 22, 8601, 10.1128/MCB.22.24.8601-8611.2002 · DOI · Paper page
- Straub, 2010, The C-terminus of p63 contains multiple regulatory elements with different functions, Cell Death Dis., 1, e5, 10.1038/cddis.2009.1 · DOI
- Suh, 2006, p63 protects the female germ line during meiotic arrest, Nature, 444, 624, 10.1038/nature05337 · DOI · Paper page
- Thut, 1995, p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60, Science, 267, 100, 10.1126/science.7809597 · DOI · Paper page
- Trink, 1998, A new human p53 homologue, Nat. Med., 4, 747, 10.1038/nm0798-747 · DOI · Paper page
- Yang, 1998, p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities, Mol. Cell, 2, 305, 10.1016/S1097-2765(00)80275-0 · DOI · Paper page
- Yang, 1999, p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development, Nature, 398, 714, 10.1038/19539 · DOI · Paper page
- Yang, 2000, p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours, Nature, 404, 99, 10.1038/35003607 · DOI · Paper page
- Ying, 2005, DNA-binding and transactivation activities are essential for TAp63 protein degradation, Mol. Cell. Biol., 25, 6154, 10.1128/MCB.25.14.6154-6164.2005 · DOI
Cited by
Pathological Unfoldomics of Uncontrolled Chaos: Intrinsically Disordered Proteins and Human Diseases
Uversky, V. N., Davé, V., Iakoucheva, L. M., Malaney, P., Metallo, S. J., Pathak, R. R., & Joerger, A. C. (2014) · Chemical Reviews · doi:10.1021/cr400713r · Cited by 288
DNA repair and aging: The impact of the p53 family
Nicolai, S., Rossi, A., Di Daniele, N., Melino, G., Annicchiarico-Petruzzelli, M., & Raschellà, G. (2015) · Aging · doi:10.18632/aging.100858 · Cited by 118
Structural Evolution and Dynamics of the p53 Proteins
Chillemi, G., Kehrloesser, S., Bernassola, F., Desideri, A., Dötsch, V., Levine, A. J., & Melino, G. (2017) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a028308 · Cited by 65
Self-citationZhang, Q., Balourdas, D.-I., Baron, B., Senitzki, A., Haran, T. E., Wiman, K. G., Soussi, T., & Joerger, A. C. (2022) · Cell Death & Disease · doi:10.1038/s41419-022-04653-8 · Cited by 14
Metadata
- Authors
- Deutsch, G. B., Zielonka, E. M., Coutandin, D., Weber, T. A., Schäfer, B., Hannewald, J., Luh, L. M., Durst, F. G., Ibrahim, M., Hoffmann, J., Niesen, F. H., Sentürk, A., Kunkel, H., Brutschy, B., Schleiff, E., Knapp, S., Acker-Palmer, A., Grez, M., McKeon, F., & Dötsch, V.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2011-02
- Volume
- 144
- Issue
- 4
- Pages
- 566-576
- ISSN
- 0092-8674
- Cited by
- 131
- References
- 5
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- creativecommons.org/licenses/by/3.0/ (vor, 896 d)
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- The paper
- Deutsch, G. B., Zielonka, E. M., Coutandin, D., Weber, T. A., Schäfer, B., Hannewald, J., Luh, L. M., Durst, F. G., Ibrahim, M., Hoffmann, J., Niesen, F. H., Sentürk, A., Kunkel, H., Brutschy, B., Schleiff, E., Knapp, S., Acker-Palmer, A., Grez, M., McKeon, F., & Dötsch, V. (2011). DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer. Cell. https://doi.org/10.1016/j.cell.2011.01.013
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