Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

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Items 201–300 of 1,006

1. KRAS4A directly regulates hexokinase 1
   Amendola, Caroline R., Mahaffey, James P., Parker, Seth J., Ahearn, Ian M., Chen, Wei-Ching, Zhou, Mo, Court, Helen, Shi, Jie, Mendoza, Sebastian L., Morten, Michael J. et al. · 2019 · Nature
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4. Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer
   Julian Świerczyński · 2014 · World Journal of Gastroenterology
5. The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth
   Arvin M. Gouw, Katherine Margulis, Natalie S. Liu, Sudha Janaki Raman, Anthony Mancuso, Georgia G. Toal, Ling Tong, Adriane R. Mosley, Annie Lee Hsieh, Delaney K. Sullivan et al. · 2019 · Cell Metabolism
6. Targeting Pyrimidine Metabolism in the Era of Precision Cancer Medicine
   Wanyan Wang, Jiayan Cui, Hui Ma, Weiqiang Lü, Jin Yan Huang · 2021 · Frontiers in Oncology
7. KRAS inhibitors: resistance drivers and combinatorial strategies
   Tamara Isermann, Christine Sers, Channing J. Der, Bjoern Papke · 2024 · Trends in cancer
8. Oncogenic <i>Kras</i> drives invasion and maintains metastases in colorectal cancer
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9. Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer
   Marybeth Anderson, Raoud Marayati, Richard A. Moffitt, Jen Jen Yeh · 2016 · Oncotarget
10. A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source
    Susanne B. Breitkopf, Stéphane J. H. Ricoult, Min Yuan, Ying Xu, David A. Peake, Brendan D. Manning, John M. Asara · 2017 · Metabolomics
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    Patra, Krushna C., Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S. et al. · 2018 · Nature Cell Biology
12. CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis
    Jenna K. Minami, Danielle Morrow, Nicholas A. Bayley, Elizabeth G. Fernandez, Jennifer J. Salinas, Christopher Tse, Henan Zhu, Baolong Su, Rhea Plawat, Anthony E. Jones et al. · 2023 · Cancer Cell
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    Eric C. Cheung, Dimitris Athineos, Pearl Lee, Rachel A. Ridgway, Wendy Lambie, Colin Nixon, Douglas Strathdee, Karen Blyth, Owen James Sansom, Karen H. Vousden · 2013 · Developmental Cell
14. Diverting Glycolysis to Combat Oxidative Stress
    Edouard Mullarky, Lewis C. Cantley · 2015 · Springer eBooks
15. Survival of pancreatic cancer cells lacking KRAS function
    Muzumdar, Mandar Deepak, Chen, Pan-Yu, Dorans, Kimberly Judith, Chung, Katherine Minjee, Bhutkar, Arjun, Hong, Erin, Noll, Elisa M., Sprick, Martin R., Trumpp, Andreas, Jacks, Tyler · 2017 · Nature Communications
16. Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene
    Arnaldur Hall, Kathrine Damm Meyle, Marina Krarup Lange, Martin Klima, May Sanderhoff, Christina Dahl, Cecilie Abildgaard, Katrine Thorup, Seyed Moein Moghimi, Per Bo Jensen et al. · 2013 · Oncotarget
17. KRAS-related proteins in pancreatic cancer
    Karen M. Mann, Haoqiang Ying, Joseph M. Juan, Nancy A. Jenkins, Neal G. Copeland · 2016 · Pharmacology & Therapeutics
18. Metastatic pancreatic cancer is dependent on oncogenic Kras in mice
    Collins, Meredith A., Brisset, Jean-Christophe, Zhang, Yaqing, Bednar, Filip, Pierre, Josette, Heist, Kevin A., Galbán, Craig J., Galbán, Stefanie, di Magliano, Marina Pasca · 2012 · PLoS ONE
19. RAS: Striking at the Core of the Oncogenic Circuitry
    Gimple, Ryan C., Wang, Xiuxing · 2019 · Frontiers in Oncology
20. Famine versus feast: understanding the metabolism of tumors in vivo
    Jared R. Mayers, Matthew G. Vander Heiden · 2015 · Trends in Biochemical Sciences
21. The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis
    Vassilis Papalazarou, Tong Zhang, Nikki R. Paul, Amélie Juin, Marco Cantini, Oliver D.K. Maddocks, Manuel Salmerón‐Sánchez, Laura M. Machesky · 2020 · Nature Metabolism
22. Disorders of cancer metabolism: The therapeutic potential of cannabinoids
    Dingya Sun, Xin Li, Shengdan Nie, Jiajia Liu, Shan Wang · 2022 · Biomedicine & Pharmacotherapy
23. Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS
    Ross, Sarah J., Revenko, Alexey S., Hanson, Lyndsey L., Ellston, Rebecca, Staniszewska, Anna, Whalley, Nicky, Pandey, Sanjay K., Revill, Mitchell, Rooney, Claire, Buckett, Linda K. et al. · 2017 · Science Translational Medicine
24. Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells
    Franziska Baenke, Barbara Chaneton, Matthew Smith, Niels J. F. van den Broek, Kate Hogan, Haoran Tang, Amaya Virós, Matthew J. Martin, Laura C.A. Galbraith, María Romina Girotti et al. · 2015 · Molecular Oncology
25. YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect
    Yichao Hou, Qingwei Zhang, Wenjing Pang, Lidan Hou, Yu Liang, Xu Han, Xiaoyu Luo, Ping Wang, Xintian Zhang, Lei Li et al. · 2021 · Cell Death and Differentiation
26. Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach
    Chen, Lian, Cui, Hengmin · 2015 · International Journal of Molecular Sciences
27. Metabolic Signaling to the Nucleus in Cancer
    Sydney L. Campbell, Kathryn E. Wellen · 2018 · Molecular Cell
28. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer
    Adrián Vallejo, Naiara Perurena, Elizabeth Guruceaga, Pawel Karol Mazur, Susana Martínez-Canarias, Carolina Zandueta, Karmele Valencia, Andrea Arricibita, Dana M. Gwinn, Leanne C. Sayles et al. · 2017 · Nature Communications
29. Oncogene-Directed Alterations in Cancer Cell Metabolism
    Nagarajan, Arvindhan, Malvi, Parmanand, Wajapeyee, Narendra · 2016 · Trends in Cancer
30. Applications of metabolomics to study cancer metabolism
    Kaushik, Akash K., DeBerardinis, Ralph J. · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
31. KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment
    Daniel Zeitouni, Yuliya Pylayeva‐Gupta, Channing J. Der, Kirsten L. Bryant · 2016 · Cancers
32. Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression
    Christine E. Kaiser, Natalie A. Van Ert, Prashansa Agrawal, Reena Chawla, Danzhou Yang, Laurence H. Hurley · 2017 · Journal of the American Chemical Society
33. Arginase 1 is a key driver of immune suppression in pancreatic cancer
    Rosa Elena Menjivar, Zeribe C. Nwosu, Wenting Du, Katelyn L. Donahue, Hanna S. Hong, Carlos E. Espinoza, Kristee L. Brown, Ashley Velez-Delgado, Wei Yan, Fatima Lima et al. · 2023 · eLife
34. Exploiting the bad eating habits of Ras-driven cancers
    Eileen White · 2013 · Genes & Development
35. Harnessing metabolic dependencies in pancreatic cancers
    Joel Encarnación-Rosado, Alec C. Kimmelman · 2021 · Nature Reviews Gastroenterology & Hepatology
36. Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer
    Meifang Yu, Nicholas D. Nguyen, Yanqing Huang, Daniel Lin, Tara N. Fujimoto, Jessica M. Molkentine, Amit Deorukhkar, Ya’an Kang, Francis Anthony San Lucas, Conrad J. Fernandes et al. · 2019 · JCI Insight
37. Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses
    Julianna Blagih, Fabio Zani, Probir Chakravarty, Marc Hennequart, Steven E. Pilley, Sebastijan Hobor, Andreas K. Hock, Josephine B. Walton, Jennifer P. Morton, Eva Camilla Gronroos et al. · 2020 · Cell Reports
38. Targeting p300/CBP Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism
    Ling-Yan Cai, Shijie Chen, Sen-Hao Xiao, Qin-Juan Sun, Chen‐Hong Ding, Bai-Nan Zheng, Xinyan Zhu, Shuqing Liu, Feng Yang, Ya-Xi Yang et al. · 2020 · Cancer Research
39. Metabolic rewiring in melanoma
    Boris I. Ratnikov, David A. Scott, Andrei L. Osterman, Jeffrey W. Smith, Ze’ev A. Ronai · 2016 · Oncogene
40. Analytical and Biochemical Perspectives of Protein O-GlcNAcylation
    Junfeng Ma, Ci Wu, Gerald Warren Hart · 2021 · Chemical Reviews
41. Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells
    Bradley Smith, Xenia Schafer, Aslihan Ambeskovic, Cody M. Spencer, Hartmut Land, Joshua C. Munger · 2016 · Cell Reports
42. The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring
    Ferdinando Chiaradonna, Francesca Ricciardiello, Roberta Palorini · 2018 · Cells
43. Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule
    Chiara Marchetti, Katherine G. Zyner, Stephan A. Ohnmacht, Mathew P. Robson, Shozeb M Haider, Jennifer P. Morton, Giovanni Marsico, Tam D. Vo, Sarah Laughlin, Ahmed A. Ahmed et al. · 2018 · Journal of Medicinal Chemistry
44. KRAS Controls Pancreatic Cancer Cell Lipid Metabolism and Invasive Potential through the Lipase HSL
    Cody N. Rozeveld, Katherine M. Johnson, Lizhi Zhang, Gina L. Razidlo · 2020 · Cancer Research
45. Adapt and conquer: Metabolic flexibility in cancer growth, invasion and evasion
    Peter A. Kreuzaler, Yulia Panina, Joanna Segal, M. Yuneva · 2019 · Molecular Metabolism
46. Physical biology of the cancer cell glycocalyx
    Joe Chin‐Hun Kuo, Jay G. Gandhi, Roseanna N. Zia, Matthew J. Paszek · 2018 · Nature Physics
47. Tumour microenvironment and metabolic plasticity in cancer and cancer stem cells: Perspectives on metabolic and immune regulatory signatures in chemoresistant ovarian cancer stem cells
    Nuzhat Ahmed, Ruth M. Escalona, Dilys T.H. Leung, Emily Chan, George Kannourakis · 2018 · Seminars in Cancer Biology
48. Dihydroorotate dehydrogenase in oxidative phosphorylation and cancer
    Štěpána Boukalová, Soňa Hubáčková, Mirko Milošević, Zuzana Ezrova, Jiřı́ Neužil, Jakub Rohlena · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
49. Plasticity and Dedifferentiation within the Pancreas: Development, Homeostasis, and Disease
    Sapna Puri, Alexandra E. Folias, M. Hebrok · 2014 · Cell Stem Cell
50. O-GlcNAc in cancer biology
    Zhiyuan Ma, Keith Vosseller · 2013 · Amino Acids
51. Uridine-derived ribose fuels glucose-restricted pancreatic cancer
    Zeribe C. Nwosu, Matthew H. Ward, Peter Sajjakulnukit, Pawan Poudel, Chanthirika Ragulan, Steven Kasperek, Megan D. Radyk, Damien Sutton, Rosa Elena Menjivar, Anthony C. Andren et al. · 2023 · Nature
52. Pharmacological targeting of RAS: recent success with direct inhibitors
    O’Bryan, John P. · 2019 · Pharmacological Research
53. Associations Between Somatic Mutations and Metabolic Imaging Phenotypes in Non–Small Cell Lung Cancer
    Stephen S. F. Yip, John Kim, Thibaud P. Coroller, Chintan Parmar, Emmanuel Rios Velazquez, Elizabeth Huynh, Raymond H. Mak, Hugo J.W.L. Aerts · 2016 · Journal of Nuclear Medicine
54. mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
    Alexander J. Valvezan, Marc Turner, Amine Belaïd, Hilaire Colletta Lam, Spencer K. Miller, Molly C. McNamara, Christian V. Baglini, Benjamin E. Housden, Norbert Perrimon, David J. Kwiatkowski et al. · 2017 · Cancer Cell
55. Metabolic reprogramming, sensing, and cancer therapy
    Youxiang Mao, Ziyan Xia, Wenjun Xia, Peng Jiang · 2024 · Cell Reports
56. Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer
    Hou, Pingping, Kapoor, Avnish, Zhang, Qiang, Li, Jiexi, Wu, Chang-Jiun, Li, Jun, Lan, Zhengdao, Tang, Ming, Ma, Xingdi, Ackroyd, Jeffrey J. et al. · 2020 · Cancer Discovery
57. Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk
    Carlos A. Orozco, Neus Martínez‐Bosch, Pedro Enrique Guerrero, Judith Vinaixa, Tomás Dalotto‐Moreno, Mar Iglesias, Mireia Moreno, Magdolna Djurec, Françoise Poirier, Hans‐Joachim Gabius et al. · 2018 · Proceedings of the National Academy of Sciences
58. Stromal Modulation and Treatment of Metastatic Pancreatic Cancer with Local Intraperitoneal Triple miRNA/siRNA Nanotherapy
    Ying Xie, Hang Yu, Yazhe Wang, Richard L. Sleightholm, Dipakkumar R. Prajapati, Johannes Bader, Ao Yu, Weimin Tang, Lee Jaramillo, Jing Li et al. · 2020 · ACS Nano
59. Targeting Metabolism in Cancer Cells and the Tumour Microenvironment for Cancer Therapy
    Jiaqi Li, Jie Qing Eu, Li Ren Kong, Lingzhi Wang, Yaw Chyn Lim, Boon Cher Goh, Andrea Li‐Ann Wong · 2020 · Molecules
60. Developing dietary interventions as therapy for cancer
    Samuel R. Taylor, John N. Falcone, Lewis C. Cantley, Marcus DaSilva Goncalves · 2022 · Nature reviews. Cancer
61. Bioenergetic Adaptations in Chemoresistant Ovarian Cancer Cells
    Sajad Ahmad Dar, Jasdeep Chhina, İsmail Mert, Dhananjay Arun Chitale, Thomas Buekers, Hareena Kaur, Shailendra Giri, Adnan R. Munkarah, Ramandeep Rattan · 2017 · Scientific Reports
62. Cancer associated fibroblast FAK regulates malignant cell metabolism
    Fevzi Demircioglu, Jun Wang, Juliana B. Candido, Ana S.H. Costa, Pedro Casado, Beatriz de Luxán‐Delgado, Louise E. Reynolds, Jesús Gómez-Escudero, Emma Newport, Vinothini Rajeeve et al. · 2020 · Nature Communications
63. Stromal cues regulate the pancreatic cancer epigenome and metabolome
    Sherman, Mara H., Yu, Ruth T., Tseng, Tiffany W., Sousa, Cristovao M., Liu, Sihao, Truitt, Morgan L., He, Nanhai, Ding, Ning, Liddle, Christopher, Atkins, Annette R. et al. · 2017 · Proceedings of the National Academy of Sciences
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    Mark Masin, Jessica Vázquez, Simona Rossi, Svenja Groeneveld, Natasha Samson, Petra Catalina Schwalie, Bart Deplancke, Laura E. Frawley, Jérôme Gouttenoire, Darius Moradpour et al. · 2014 · Cancer & Metabolism
65. Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC–MS/MS
    Min Yuan, Daniel M. Kremer, He Huang, Susanne B. Breitkopf, Issam Ben‐Sahra, Brendan D. Manning, Costas Andreas Lyssiotis, John M. Asara · 2019 · Nature Protocols
66. Carcinogenesis of Pancreatic Ductal Adenocarcinoma
    Peter Störz, Howard C. Crawford · 2020 · Gastroenterology
67. The plasticity of pancreatic cancer metabolism in tumor progression and therapeutic resistance
    Douglas E. Biancur, Alec C. Kimmelman · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
68. Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest
    Michela Capello, Sammy Ferri Borgogno, Chiara Riganti, Michelle Samuel Chattaragada, Moitza Principe, Cecilia Roux, Weidong Zhou, Emanuel F. Petricoin, Paola Cappello, Francesco Novelli · 2015 · Oncotarget
69. Fructose contributes to the Warburg effect for cancer growth
    Takahiko Nakagawa, Miguel Angel Lanaspa, Íñigo San Millán, Mehdi A. Fini, Christopher J. Rivard, Laura Gabriela Sánchez‐Lozada, Ana Andrés-Hernando, Dean R. Tolan, Richard J. Johnson · 2020 · Cancer & Metabolism
70. ALDOA functions as an oncogene in the highly metastatic pancreatic cancer
    Shunrong Ji, Bo Zhang, Jiang Liu, Yi Qin, Chen Liang, Si Shi, Kaizhou Jin, Dingkong Liang, Wenyan Xu, Huaxiang Xu et al. · 2016 · Cancer Letters
71. TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
    Jie Cheng, Yan Huang, Xiaohui Zhang, Yue Yu, Shumin Wu, Jing Jiao, Linh My Tran, Wanru Zhang, Ran Liu, Liuzhen Zhang et al. · 2020 · Nature Communications
72. Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells
    Qian, Yanrong, Wang, Xuan, Liu, Yi, Li, Yunsheng, Colvin, Robert A., Tong, Lingying, Wu, Shiyong, Chen, Xiaozhuo · 2014 · Cancer Letters
73. The role of hypoxia in pancreatic cancer: a potential therapeutic target?
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74. Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma
    Arvin M. Gouw, Lívia S. Eberlin, Katherine Margulis, Delaney K. Sullivan, Georgia G. Toal, Ling Tong, Richard N. Zare, Dean W. Felsher · 2017 · Proceedings of the National Academy of Sciences
75. The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition
    Justin Goodwin, Michael L. Neugent, Shin Yup Lee, Joshua H. Choe, Hyunsung Choi, Dana M. R. Jenkins, Robin J. Ruthenborg, Maddox W. Robinson, Ji Yun Jeong, Masaki Wake et al. · 2017 · Nature Communications
76. A Small Molecule with Big Impact: MRTX1133 Targets the KRASG12D Mutation in Pancreatic Cancer
    Daoyan Wei, Liang Wang, Xiangsheng Zuo, Anirban Maitra, Robert S. Bresalier · 2023 · Clinical Cancer Research
77. ARF6 and AMAP1 are major targets of <i>KRAS</i> and <i>TP53</i> mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer
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78. Mutations in key driver genes of pancreatic cancer: molecularly targeted therapies and other clinical implications
    Hu, Hai-feng, Ye, Zeng, Qin, Yi, Xu, Xiao-wu, Yu, Xian-jun, Zhuo, Qi-feng, Ji, Shun-rong · 2021 · Acta Pharmacologica Sinica
79. The redox requirements of proliferating mammalian cells
    Aaron M. Hosios, Matthew G. Vander Heiden · 2018 · Journal of Biological Chemistry
80. Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
    Sarbajeet Nagdas, Jennifer A. Kashatus, Aldo Nascimento, Syed Saad Hussain, Riley E. Trainor, Sarah R. Pollock, Sara J. Adair, Alex D. Michaels, Hiromi Sesaki, Edward B. Stelow et al. · 2019 · Cell Reports
81. O-GlcNAcylation: The Sweet Side of the Cancer
    Rafaela Muniz de Queiroz, Érika Carvalho, Wagner B. Dias · 2014 · Frontiers in Oncology
82. FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells
    Hyeonju Yeo, Costas Andreas Lyssiotis, Yuqing Zhang, Haoqiang Ying, John M. Asara, Lewis C. Cantley, Ji-Hye Paik · 2013 · The EMBO Journal
83. Redox control of glutamine utilization in cancer
    Lilia Alberghina, Daniela Gaglio · 2014 · Cell Death and Disease
84. Metabolism-Based Therapeutic Strategies Targeting Cancer Stem Cells
    Petra Jagušt, Beatriz de Luxán‐Delgado, Beatriz Parejo-Alonso, Patricia Sancho · 2019 · Frontiers in Pharmacology
85. Cancer’s Fuel Choice: New Flavors for a Picky Eater
    Gina M. DeNicola, Lewis C. Cantley · 2015 · Molecular Cell
86. Oxidative Phosphorylation: A Target for Novel Therapeutic Strategies Against Ovarian Cancer
    Amruta P. Nayak, Arvinder Kapur, Lisa Marie Barroilhet, Manish S. Patankar · 2018 · Cancers
87. Combined MEK and PI3K Inhibition in a Mouse Model of Pancreatic Cancer
    Brinda Alagesan, Gianmarco Contino, Alexander R. Guimarães, Ryan Bruce Corcoran, Vikram Deshpande, Gregory R. Wojtkiewicz, Aram F. Hezel, Kwok‐Kin Wong, Massimo F. Loda, Ralph Weissleder et al. · 2014 · Clinical Cancer Research
88. In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer
    Alessandro Carugo, Giannicola Genovese, Sahil Seth, Luigi Nezi, Johnathon Lynn Rose, Daniela Bossi, Angelo Cicalese, Parantu K. Shah, Andrea Viale, Piergiorgio Pettazzoni et al. · 2016 · Cell Reports
89. Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer
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    Arvindhan Govindasamy Nagarajan, Shaillay Kumar Dogra, Lisha Sun, Neeru Gandotra, Thuy Ho, Guoping Cai, Gary W. Cline, Priti Kumar, Robert A. Cowles, Narendra Wajapeyee · 2017 · Molecular Cell
91. Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
    Ajaz Ahmad Bhat, Sabah Nisar, Selma Maacha, Tatiana Carneiro-Lobo, Sabah Akhtar, Kodappully Sivaraman Siveen, Nissar Ahmad Wani, Arshi Rizwan, Puneet Bagga, Mayank Kumar Singh et al. · 2021 · Molecular Cancer
92. Wild-Type H- and N-Ras Promote Mutant K-Ras-Driven Tumorigenesis by Modulating the DNA Damage Response
    Elda Grabocka, Yuliya Pylayeva‐Gupta, Mathew V. Jones, Veronica Lubkov, Eyoel Yemanaberhan, Laura Jane Taylor, Hao Hsuan Jeng, Dafna Bar‐Sagi · 2014 · Cancer Cell
93. O-GlcNAc in cancer: An Oncometabolism-fueled vicious cycle
    John A. Hanover, Weiping Chen, Michelle R. Bond · 2018 · Journal of Bioenergetics and Biomembranes
94. KRAS-Driven Metabolic Rewiring Reveals Novel Actionable Targets in Cancer
    Emanuela Pupo, Daniele Avanzato, Emanuele Middonti, Federico Bussolino, Letizia Lanzetti · 2019 · Frontiers in Oncology
95. The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer
    Jiyeon Kim, Hyun Min Lee, Feng Cai, Bookyung Ko, Chendong Yang, Elizabeth L. Lieu, Nefertiti Muhammad, Shawn Rhyne, Kailong Li, Mohamed Haloul et al. · 2020 · Nature Metabolism
96. Perspectives in the treatment of pancreatic adenocarcinoma
    Angel Cid Arregui · 2015 · World Journal of Gastroenterology
97. ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis
    Yun‐Xin Lu, Huai‐Qiang Ju, Zexian Liu, Dong-liang Chen, Yun Wang, Qi Zhao, Qi-Nian Wu, Zhao-Lei Zeng, Hai-Bo Qiu, Pei-Shan Hu et al. · 2018 · Cancer Research
98. Genetically Engineered Mouse Models of Pancreatic Cancer
    Christoph Benedikt Westphalen, Kenneth P. Olive · 2012 · The Cancer Journal
99. Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway
    Xiaoyu Ma, Lin Wang, De Huang, Yunyan Li, Dongdong Yang, Tingting Li, Fudong Li, Linchong Sun, Haoran Wei, Kun He et al. · 2017 · Nature Communications
100. Hydrogen sulfide perturbs mitochondrial bioenergetics and triggers metabolic reprogramming in colon cells
     Marouane Libiad, Victor Vitvitsky, Trever Bostelaar, Daniel W. Bak, Ho‐Joon Lee, Naoya Sakamoto, Eric R. Fearon, Costas Andreas Lyssiotis, Eranthie Weerapana, Ruma V. Banerjee · 2019 · Journal of Biological Chemistry