Alzheimer Mechanisms and Therapeutic Strategies
Huang, Yadong, Mucke, Lennart·2012·Cell
Cited by (1,005)
Items 201–300 of 1,005
- Biomimetic ApoE-Reconstituted High Density Lipoprotein Nanocarrier for Blood–Brain Barrier Penetration and Amyloid Beta-Targeting Drug DeliveryQingxiang Song, Huahua Song, Jianrong Xu, Jialin Huang, Hu Meng, Xiao Qin Gu, Juan Chen, Gang Zheng, Hongzhuan Chen, Xiaoling Gao · 2016 · Molecular Pharmaceutics
- Nanotechnology-Based Drug Delivery Systems for Targeting, Imaging and Diagnosis of Neurodegenerative DiseasesSibel Bozdağ Pehlivan · 2013 · Pharmaceutical Research
- Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer’s diseaseR. Alkallas, L. Fish, H. Goodarzi, H. Najafabadi · 2017 · Nature Communications
- Theories of Aging: An Ever-Evolving FieldСергиев Петр Владимирович, Olga А. Dontsova, Grigory V. Berezkin · 2015 · Acta Naturae
- High resolution dissection of reactive glial nets in Alzheimer’s diseaseBouvier, David S., Jones, Emma V., Quesseveur, Gaël, Davoli, Maria Antonietta, A. Ferreira, Tiago, Quirion, Rémi, Mechawar, Naguib, Murai, Keith K. · 2016 · Scientific Reports
- Intranasal insulin alleviates cognitive deficits and amyloid pathology in young adult APP swe/ PS 1dE9 miceYanfang Mao, Zhangyu Guo, Tingting Zheng, Yasi Jiang, Yaping Yan, Xinzhen Yin, Yanxing Chen, Baorong Zhang · 2016 · Aging Cell
- Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse ModelHui-Feng Mai, Weihao Fan, Yan Wang, Yu-Jie Cai, Xiaohui Li, Feng Chen, Xiongjin Chen, Jing-Qi Yang, Pei Tang, Hui-Yi Chen et al. · 2019 · Molecular Therapy: Nucleic Acids
- Near-Infrared Light-Powered Janus Nanomotor Significantly Facilitates Inhibition of Amyloid-β FibrillogenesisWei Liu, Wenjuan Wang, Xiaoyan Dong, Yan Ping Sun · 2020 · ACS Applied Materials & Interfaces
- Polygenic regression uncovers trait-relevant cellular contexts through pathway activation transformation of single-cell RNA sequencing dataYunlong Ma, Chunyu Deng, Yijun Zhou, Yaru Zhang, Fei Qiu, Dingping Jiang, Gongwei Zheng, Jingjing Li, Jianwei Shuai, Yan Zhang et al. · 2023 · Cell Genomics
- Amyloid β directly interacts with NLRP3 to initiate inflammasome activation: identification of an intrinsic NLRP3 ligand in a cell-free systemAyaka Nakanishi, Naoe Kaneko, Hiroyuki Takeda, Tatsuya Sawasaki, Shinnosuke Morikawa, Wei Zhou, Mie Kurata, Toshihiro Yamamoto, Sheikh Mohammad Fazle Akbar, Tamotsu Zako et al. · 2018 · Inflammation and Regeneration
- Apolipoprotein E4 Causes Age- and Sex-Dependent Impairments of Hilar GABAergic Interneurons and Learning and Memory Deficits in MiceLeung, Laura, Andrews-Zwilling, Yaisa, Yoon, Seo Yeon, Jain, Sachi, Ring, Karen, Dai, Jessica, Wang, Max Mu, Tong, Leslie, Walker, David, Huang, Yadong · 2012 · PLoS ONE
- Neurodegeneration-Associated Protein Fragments as Short-Lived Substrates of the N-End Rule PathwayChristopher S. Brower, Konstantin I. Piatkov, Alexander J. Varshavsky · 2013 · Molecular Cell
- Executive Function Changes before Memory in Preclinical Alzheimer’s Pathology: A Prospective, Cross-Sectional, Case Control StudyMichael G. Harrington, Jiarong Chiang, Janice M. Pogoda, Megan E. Gomez, Kris Thomas, Sarah Marion, Karen J. Miller, Prabha Siddarth, Xinyao Yi, Feimeng Zhou et al. · 2013 · PLoS ONE
- Lactate metabolism in neurodegenerative diseasesChaoguang Yang, Rui‐Yuan Pan, Fangxia Guan, Zengqiang Yuan · 2023 · Neural Regeneration Research
- Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6Zhu, Kaichuan, Xiang, Xianyuan, Filser, Severin, Marinković, Petar, Dorostkar, Mario M., Crux, Sophie, Neumann, Ulf, Shimshek, Derya R., Rammes, Gerhard, Haass, Christian et al. · 2018 · Biological Psychiatry
- Protective Effects of Ferulic Acid in Amyloid Precursor Protein Plus Presenilin-1 Transgenic Mouse Model of Alzheimer DiseaseJi-Jing Yan, Jun‐Sub Jung, Taek-Keun Kim, Md. Ashraful Hasan, Chang-Won Hong, Ju‐Suk Nam, Dong‐Keun Song · 2012 · Biological and Pharmaceutical Bulletin
- Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer's Disease-Related PathologyAdam D. Bachstetter, Christopher Mark Norris, Pradoldej M Sompol, Donna M. Wilcock, Danielle S. Goulding, Janna H. Neltner, Daret K. St. Clair, Daniel Martin Watterson, Linda J. Van Eldik · 2012 · Journal of Neuroscience
- Purinergic receptors as potential therapeutic targets in Alzheimer's diseaseLucas T. Woods, Deepa Ajit, Jean M. Camden, Laurie Erb, Gary A. Weisman · 2015 · Neuropharmacology
- Astroglia as a cellular target for neuroprotection and treatment of neuro‐psychiatric disordersBeihui Liu, Anja G. Teschemacher, Sergey Kasparov · 2017 · Glia
- Advances in developing therapeutic strategies for Alzheimer's diseaseThuy Trang Nguyen, Thi Thuy Dung Nguyen, Thi Kim Oanh Nguyen, Tuong Kha Vo, Vo Van Giau · 2021 · Biomedicine & Pharmacotherapy
- Brilliant Blue G improves cognition in an animal model of Alzheimer’s disease and inhibits amyloid-β-induced loss of filopodia and dendrite spines in hippocampal neuronsXiaowei Chen, Juwei Hu, L. Jiang, Shujun Xu, Bingqin Zheng, C Wang, Jun‐Fang Zhang, Xiaofei Wei, Lan Yi Chang, QingMei Wang · 2014 · Neuroscience
- GABAergic neurotransmission and new strategies of neuromodulation to compensate synaptic dysfunction in early stages of Alzheimer’s diseaseMauricio O. Nava-Mesa, Lydia Jiménez‐Díaz, Javier Yajeya, Juan D. Navarro‐López · 2014 · Frontiers in Cellular Neuroscience
- Preparation and Evaluation of Phospholipid-Based Complex of Standardized Centella Extract (SCE) for the Enhanced Delivery of PhytoconstituentsSuprit Dilip Saoji, Nishikant A. Raut, Pradip W. Dhore, Chandrashekhar D. Borkar, Michael Popielarczyk, Vivek S. Dave · 2015 · The AAPS Journal
- Design of a Molecular Hybrid of Dual Peptide Inhibitors Coupled on AuNPs for Enhanced Inhibition of Amyloid β‐Protein Aggregation and CytotoxicityNeng Xiong, Yan-Jiao ZHAO, Xiaoyan Dong, Jie Zheng, Yan Ping Sun · 2017 · Small
- Recent Advances in Molecular Pathways and Therapeutic Implications Targeting Mitochondrial Dysfunction for Alzheimer’s DiseaseRishika Dhapola, Phulen Sarma, Bikash Medhi, Ajay Prakash, Dibbanti HariKrishnaReddy · 2021 · Molecular Neurobiology
- β-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptorsAmulya Nidhi Shrivastava, Jacob M. Kowalewski, Marianne L. Renner, Luc Bousset, Annette Koulakoff, Ronald Melki, Christian Giaume, Antoine Triller · 2013 · Glia
- Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s diseaseCheng, Yuan, He, Chen-Yang, Tian, Ding-Yuan, Chen, Si-Han, Ren, Jun-Rong, Sun, Hao-Lun, Xu, Man-Yu, Tan, Cheng-Rong, Fan, Dong-Yu, Jian, Jie-Ming et al. · 2023 · Acta Neuropathologica
- Intermittent fasting protects against Alzheimer’s disease in mice by altering metabolism through remodeling of the gut microbiotaPan, Rui-Yuan, Zhang, Jing, Wang, Jinlei, Wang, Yingyi, Li, Zhihui, Liao, Yang, Liao, Yajin, Zhang, Chenggang, Liu, Zhiqiang, Song, Lijuan et al. · 2022 · Nature Aging
- Microglia in Alzheimer’s disease: A target for immunotherapyShoutang Wang, Marco Colonna · 2019 · Journal of Leukocyte Biology
- Transcranial Magnetic Stimulation in Alzheimer’s Disease: Are We Ready?Marina Weiler, Kevin C. Stieger, Jeffrey M. Long, Peter R. Rapp · 2019 · eNeuro
- Copper-Catalyzed Asymmetric Aminocyanation of Arylcyclopropanes for Synthesis of γ-Amino NitrilesShengbiao Yang, Lihong Wang, Hongwei Zhang, Chunyang Liu, Linli Zhang, Xiaomin Wang, Ge Zhang, Yan Li, Qian Zhang · 2018 · ACS Catalysis
- Review of the advances in treatment for Alzheimer disease: strategies for combating β-amyloid proteinJaume Folch, Miren Ettcheto, D. Petrov, Sònia Abad, Ignacio Pedrós, M. Marin, Jordi Olloquequi, Antoni Camins · 2017 · Neurología (English Edition)
- A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouseMin Sung Gee, Seung Hwan Son, Seung Ho Jeon, Jimin Do, Namkwon Kim, Yeon‐Joo Ju, Soo Jin Lee, Eun Kyoung Chung, Kyung‐Soo Inn, Nam‐Jung Kim et al. · 2020 · Alzheimer s Research & Therapy
- Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial FunctionOrr, Adam L., Kim, Chaeyoung, Jimenez-Morales, David, Newton, Billy W., Johnson, Jeffrey R., Krogan, Nevan J., Swaney, Danielle L., Mahley, Robert W. · 2019 · Journal of Alzheimer's Disease
- Design, synthesis and evaluation of novel ferulic acid- O -alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's diseaseZhipei Sang, Wanli Pan, Keren Wang, Qinge Ma, Lintao Yu, Yan Gong Yang, Ping Bai, Chaoliang Leng, Qian Xu, Xiaoqing Li et al. · 2017 · European Journal of Medicinal Chemistry
- Altered d -glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer’s disease detected by dynamic glucose-enhanced MRIJianpan Huang, Peter C.M. van Zijl, Xiongqi Han, Celia M. Dong, Gerald Wai‐Yeung Cheng, Kai‐Hei Tse, Linda Knutsson, Lin Chen, Joseph H. C. Lai, Edward X. Wu et al. · 2020 · Science Advances
- Alzheimer’s Disease: Mechanism and Approach to Cell TherapyTakashi Amemori, Pavla Jendelová, Jiří Růžička, Lucia Machová Urdzíková, Eva Syková · 2015 · International Journal of Molecular Sciences
- A Step into the Future: Applications of Nanoparticle Enzyme MimicsKarsten Korschelt, Muhammad Nawaz Tahir, Wolfgang Tremel · 2018 · Chemistry - A European Journal
- Effects of Tea Catechins on Alzheimer’s Disease: Recent Updates and PerspectivesKazuki Ide, Norihiro Matsuoka, Hiroshi Yamada, Daisuke Furushima, Koji Kawakami · 2018 · Molecules
- ACE Inhibition with Captopril Retards the Development of Signs of Neurodegeneration in an Animal Model of Alzheimer’s DiseaseAbdAlla, Said, Langer, Andreas, Fu, Xuebin, Quitterer, Ursula · 2013 · International Journal of Molecular Sciences
- Acat1 Knockdown Gene Therapy Decreases Amyloid-β in a Mouse Model of Alzheimer's DiseaseStephanie R Murphy, Catherine C.Y. Chang, Godwin Dogbevia, Elena Y. Bryleva, Zachary Bowen, Mazahir T. Hasan, Ta‐Yuan Chang · 2013 · Molecular Therapy
- Transient dynamics of Aβ contribute to toxicity in Alzheimer’s diseaseE. Hubin, N. V. van Nuland, K. Broersen, K. Pauwels · 2014 · Cellular and Molecular Life Sciences
- Immunotherapy for Alzheimer's diseaseThomas Wısnıewskı, Fernando Goñi · 2014 · Biochemical Pharmacology
- An overview on recent in vivo biological application of cerium oxide nanoparticlesBaskaran Stephen Inbaraj, Bing‐Huei Chen · 2019 · Asian Journal of Pharmaceutical Sciences
- Nrf2 Ablation Promotes Alzheimer’s Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative StressPeng Ren, Jingwei Chen, Bingxuan Li, Mengzhou Zhang, Bei Yang, Xiangshen Guo, Ziyuan Chen, Hao Cheng, Pengfei Wang, Shuai-Bo Wang et al. · 2020 · Oxidative Medicine and Cellular Longevity
- Protective effects of flavonoids against Alzheimer’s disease-related neural dysfunctionsMahsa Bakhtiari, Yunes Panahi, Javad Ameli, Behrad Darvishi · 2017 · Biomedicine & Pharmacotherapy
- Neurodegenerative diseases linked to misfolded proteins and their therapeutic approaches: A reviewHena Khanam, Abad Ali, Mohd Asif, Shamsuzzaman · 2016 · European Journal of Medicinal Chemistry
- Antioxidant Berberine-Derivative Inhibits Multifaceted Amyloid ToxicityKolla Rajasekhar, Sourav Samanta, Vardhaman Bagoband, N. Arul Murugan, Thimmaiah Govindaraju · 2020 · iScience
- The Essential Role of p53-up-regulated Modulator of Apoptosis (Puma) and Its Regulation by FoxO3a Transcription Factor in β-Amyloid-induced Neuron DeathRumana Akhter, Priyankar Sanphui, Subhas Chandra Biswas · 2014 · Journal of Biological Chemistry
- Brain pathology in myotonic dystrophy: when tauopathy meets spliceopathy and RNAopathyMarie‐Laure Caillet‐Boudin, Francisco-José Fernández-Gómez, Hélène Tran, Claire‐Marie Dhaenens, Luc Buée, Nicolas Sergeant · 2014 · Frontiers in Molecular Neuroscience
- The Gastrointestinal Tract Microbiome and Potential Link to Alzheimer’s DiseaseHill, James M., Bhattacharjee, Surjyadipta, Pogue, Aileen I., Lukiw, Walter J. · 2014 · Frontiers in Neurology
- Apolipoprotein E4 produced in GABAergic interneurons causes learning and memory deficits in miceKnoferle, Johanna, Yoon, Seo Yeon, Walker, David, Leung, Laura, Gillespie, Anna K., Tong, Leslie M., Bien-Ly, Nga, Huang, Yadong · 2014 · The Journal of Neuroscience
- Una revisión de los avances en la terapéutica de la enfermedad de Alzheimer: estrategia frente a la proteína β-amiloideJaume Folch, Miren Ettcheto, D. Petrov, Sònia Abad, Ignacio Pedrós, M. Marin, Jordi Olloquequi, Antoni Camins · 2015 · Neurología
- Early Hippocampal Sharp-Wave Ripple Deficits Predict Later Learning and Memory Impairments in an Alzheimer’s Disease Mouse ModelEmily A Aery Jones, Anna K. Gillespie, Seo Yeon Yoon, Loren M. Frank, Yadong Huang · 2019 · Cell Reports
- Fisetin Rescues the Mice Brains Against D-Galactose-Induced Oxidative Stress, Neuroinflammation and Memory ImpairmentSareer Ahmad, Amjad Khan, Waqar Ali, Myeung Hoon Jo, Junsung Park, Muhammad Aimen Ikram, Myeong Ok Kim · 2021 · Frontiers in Pharmacology
- A Small Molecule p75NTR Ligand, LM11A-31, Reverses Cholinergic Neurite Dystrophy in Alzheimer's Disease Mouse Models with Mid- to Late-Stage Disease ProgressionDanielle A. Simmons, Juliet K. Knowles, Nadia P. Belichenko, Gargi Banerjee, Carly Finkle, Stephen M. Massa, Frank M. Longo · 2014 · PLoS ONE
- Cognitive deficits caused by prefrontal cortical and hippocampal neural disinhibitionTobias Bast, Marie A. Pezze, Stephanie McGarrity · 2017 · British Journal of Pharmacology
- Green Tea Consumption Affects Cognitive Dysfunction in the Elderly: A Pilot StudyIde, Kazuki, Yamada, Hiroshi, Takuma, Norikata, Park, Mijong, Wakamiya, Noriko, Nakase, Junpei, Ukawa, Yuuichi, Sagesaka, Yuko · 2014 · Nutrients
- A spiropyran-based fluorescent probe for the specific detection of β-amyloid peptide oligomers in Alzheimer's diseaseGuanglei Lv, Anyang Sun, Peng Wei, Ning Zhang, Haichuang Lan, Tao Yi · 2016 · Chemical Communications
- Anti-Viral Properties of Amyloid-β PeptidesKarine Bourgade, Gilles Dupuis, Eric H. Frost, Tamàs Fülöp · 2016 · Journal of Alzheimer s Disease
- Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1aYang, Yoosoo, Kim, Jaewook, Kim, Hye Yun, Ryoo, Nayeon, Lee, Sejin, Kim, YoungSoo, Rhim, Hyewhon, Shin, Yeon-Kyun · 2015 · Cell Reports
- Asperterpenes A and B, two unprecedented meroterpenoids from Aspergillus terreus with BACE1 inhibitory activitiesChangxing Qi, Jian Bao, Jianping Wang, Hucheng Zhu, Yongbo Xue, Xiaochuan Wang, Hua Li, Weiguang Sun, Weixi Gao, Yongji Lai et al. · 2016 · Chemical Science
- Multifunctional Selenium Quantum Dots for the Treatment of Alzheimer’s Disease by Reducing Aβ-Neurotoxicity and Oxidative Stress and Alleviate NeuroinflammationXian Guo, Qiaoshan Lie, Yanan Liu, Jia Zhi, Youcong Gong, Xiaoyu Yuan, Jie Liu · 2021 · ACS Applied Materials & Interfaces
- Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's diseaseZhipei Sang, Xiaoming Qiang, Yan Li, Wenmin Yuan, Qiang Liu, Yikun Shi, Wei Ang, Youfu Luo, Zhenghuai Tan, Yong Deng · 2015 · European Journal of Medicinal Chemistry
- GJA1 (connexin43) is a key regulator of Alzheimer’s disease pathogenesisYuji Kajiwara, Erming Wang, Minghui Wang, Wun Chey Sin, Kristen Brennand, Eric E. Schadt, Christian C. G. Naus, Joseph D. Buxbaum, Bin Zhang · 2018 · Acta Neuropathologica Communications
- Circular RNA circ_0000950 promotes neuron apoptosis, suppresses neurite outgrowth and elevates inflammatory cytokines levels via directly sponging miR-103 in Alzheimer’s diseaseHui Yang, Huan Wang, Hong Shang, Xiufen Chen, Shiqi Yang, Yang Qu, Jing Ding, Xuling Li · 2019 · Cell Cycle
- RETRACTED ARTICLE: Neuron tau-targeting biomimetic nanoparticles for curcumin delivery to delay progression of Alzheimer’s diseaseChunhong Gao, Xiaoyang Chu, Wei Gong, Jinpeng Zheng, Xiangyang Xie, Meiyan Yang, Meiyan Yang, Zhiping Li, Chunsheng Gao, Yang Yang · 2020 · Journal of Nanobiotechnology · Retracted
- Isolation Housing Exacerbates Alzheimer's Disease-Like Pathophysiology in Aged APP/PS1 MiceHe Huang, Linlin Wang, M. Cao, Charles Marshall, J. Gao, Na Xiao, Gang Hu, Ming Xiao · 2015 · The International Journal of Neuropsychopharmacology
- Protective effect of Centella asiatica against D-galactose and aluminium chloride induced rats: Behavioral and ultrastructural approachesSamaila Musa Chiroma, Mohamad Taufik Hidayat Baharuldin, Che Norma Mat Taib, Zulkhairi Amom, Saravanan Jagadeesan, Mohd Ilham Adenan, Mohamad Aris Mohd Moklas · 2018 · Biomedicine & Pharmacotherapy
- New Insights in Amyloid Beta Interactions with Human TelomeraseWang, Jiasi, Zhao, Chuanqi, Zhao, Andong, Li, Meng, Ren, Jinsong, Qu, Xiaogang · 2015 · Journal of the American Chemical Society
- Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK 3β signaling pathwayJuan Deng, Ahsan Habib, Demian F. Obregon, Steven W. Barger, Brian N. Giunta, Yan‐Jiang Wang, Huayan Hou, Darrell R. Sawmiller, Jun Tan · 2015 · Journal of Neurochemistry
- Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's diseaseMisha Y. Zilberter, Anton Ivanov, Sofya Ziyatdinova, Marat R. Mukhtarov, Anton Malkov, Alán Alpár, Giuseppe Tortoriello, Catherine H. Botting, Lívia Fülöp, Alexander A. Osypov et al. · 2012 · Journal of Neurochemistry
- An Overview of Genome-Wide Association Studies in Alzheimer’s DiseaseLuxi Shen, Jianping Jia · 2016 · Neuroscience Bulletin
- Sex difference in Alzheimer's disease: An updated, balanced and emerging perspective on differing vulnerabilitiesDena B. Dubal · 2020 · Handbook of clinical neurology
- Sustainable method for Alzheimer dementia prediction in mild cognitive impairment: Electroencephalographic connectivity and graph theory combined with apolipoprotein EVecchio, Fabrizio, Miraglia, Francesca, Iberite, Francesco, Lacidogna, Giordano, Guglielmi, Valeria, Marra, Camillo, Pasqualetti, Patrizio, Tiziano, Francesco Danilo, Rossini, Paolo Maria · 2018 · Annals of Neurology
- Essential Oils as Treatment Strategy for Alzheimerʼs Disease: Current and Future PerspectivesAnju Benny, Jaya Thomas · 2018 · Planta Medica
- A multifunctional therapeutic approach: Synthesis, biological evaluation, crystal structure and molecular docking of diversified 1H-pyrazolo[3,4-b]pyridine derivatives against Alzheimer's diseaseTarana Umar, Shruti Shalini, Md Kausar Raza, Siddharth Gusain, Jitendra Kumar, Prerna Seth, Manisha Tiwari, Nasimul Hoda · 2019 · European Journal of Medicinal Chemistry
- Molecular and Imaging Biomarkers in Alzheimer’s Disease: A Focus on Recent InsightsChiara Villa, Marialuisa Lavitrano, Elena Salvatore, Romina Combi · 2020 · Journal of Personalized Medicine
- APP as a Protective Factor in Acute Neuronal InsultsDimitri Hefter, Andreas Draguhn · 2017 · Frontiers in Molecular Neuroscience
- Multitarget drugs of plants origin acting on Alzheimer’s diseaseRusso, P., Frustaci, A., Del Bufalo, A., Fini, M., Cesario, A. · 2013 · Current Medicinal Chemistry
- Alzheimer’s disease master regulators analysis: search for potential molecular targets and drug repositioning candidatesDaiani Machado de Vargas, Marco Antônio De Bastiani, Eduardo Rigon Zimmer, Fábio Klamt · 2018 · Alzheimer s Research & Therapy
- New insights into huperzine A for the treatment of Alzheimer's diseaseHaiyan Zhang · 2012 · Acta Pharmacologica Sinica
- Emerging Therapeutics for Alzheimer's DiseaseKaren Chiang, Edward H. Koo · 2014 · The Annual Review of Pharmacology and Toxicology
- Design, synthesis and biological evaluation of novel donepezil–coumarin hybrids as multi-target agents for the treatment of Alzheimer’s diseaseSai‐Sai Xie, Jinshuai Lan, Xiaobing Wang, Zhimin Wang, Neng Jiang, Fan Li, Jia‐Jia Wu, Jin Qiang Wang, Ling‐Yi Kong · 2016 · Bioorganic & Medicinal Chemistry
- AChE Inhibition-based Multi-target-directed Ligands, a Novel Pharmacological Approach for the Symptomatic and Disease-modifying Therapy of Alzheimer's DiseaseYu Wang, Hao Wang, Hongzhuan Chen · 2016 · Current Neuropharmacology
- Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathiesJens Wagner, Sybille Krauß, Song Shi, Sergey Ryazanov, Julia Steffen, Carolin Miklitz, Andrei Leonov, Alexander Kleinknecht, Bettina Göricke, Jochen Hans Weishaupt et al. · 2015 · Acta Neuropathologica
- Mitochondrial therapeutic interventions in Alzheimer’s diseaseVo Van Giau, Seong Soo A. An, John Hulme · 2018 · Journal of the Neurological Sciences
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- Multipronged diagnostic and therapeutic strategies for Alzheimer's diseaseMadhu Ramesh, Thimmaiah Govindaraju · 2022 · Chemical Science
- Inflammation in Alzheimer’s Disease and Molecular Genetics: Recent UpdateZhigang Zhang, Yan Li, Cheung Toa Ng, You‐Qiang Song · 2015 · Archivum Immunologiae et Therapiae Experimentalis
- Impaired expression of GABA transporters in the human Alzheimer’s disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrusTessa E. Fuhrer, Thulani Hansika Palpagama, Henry John Waldvogel, Beth J. L. Synek, Clinton P. Turner, Richard L. M. Faull, Andrea Kwakowsky · 2017 · Neuroscience
- Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20‐ APP transgenic and wild‐type miceCheril Tapia‐Rojas, Nibaldo C. Inestrosa · 2017 · Journal of Neurochemistry
- Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathologyStygelbout, Virginie, Leroy, Karelle, Pouillon, Valérie, Ando, Kunie, D’Amico, Eva, Jia, Yonghui, Luo, H. Robert, Duyckaerts, Charles, Erneux, Christophe, Schurmans, Stéphane et al. · 2014 · Brain
- Decreased IL-8 levels in CSF and serum of AD patients and negative correlation of MMSE and IL-1βRaphael Hesse, Anke Wahler, Pauline Gummert, Stefanie Kirschmer, Markus Otto, Hayrettin Tumani, Jan Lewerenz, Cathrin Schnack, Christine A. F. Von Arnim · 2016 · BMC Neurology
- Hybrids: a new paradigm to treat Alzheimer’s diseaseManjinder Singh, Maninder Kaur, Navriti Chadha, Om Silakari · 2015 · Molecular Diversity
- Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug repurposing in Alzheimer's diseaseJielin Xu, Pengyue Zhang, Yin Huang, Yadi Zhou, Yuan Hou, Lynn M. Bekris, Justin Durla Lathia, Chien‐Wei Chiang, Lang Li, Andrew A. Pieper et al. · 2021 · Genome Research
- Distinct Hippocampal Expression Profiles of Long Non-coding RNAs in an Alzheimer’s Disease ModelBo Yang, Zi-an Xia, Bingwu Zhong, Xingui Xiong, Chenxia Sheng, Yang Wang, Wei Gong, Yucheng Cao, Zhe Wang, Weijun Peng · 2016 · Molecular Neurobiology
- Discovery of Leonuri and therapeutical applications: From bench to bedsideYi Zhun Zhu, Weijun Wu, Qing Zhu, Xinhua Liu · 2018 · Pharmacology & Therapeutics
- Phosphodiesterase inhibitors say NO to Alzheimer's diseaseSeyed Mohammad Nabavi, Sylwia Talarek, Joanna Listos, Seyed Fazel Nabavi, Kasi Pandima Devi, Marcos Roberto de Oliveira, Devesh Tewari, Sandro Argüelles, Saeed Mehrzadi, Azam Hosseinzadeh et al. · 2019 · Food and Chemical Toxicology
- Neuronal Activity and CaMKII Regulate Kinesin-Mediated Transport of Synaptic AMPARsFrédéric J. Hoerndli, Rui Wang, Jerry E. Mellem, Angy J. Kallarackal, Penelope J. Brockie, Colin M. Thacker, David M. Madsen, Andres Villu Maricq · 2015 · Neuron