Alzheimer Mechanisms and Therapeutic Strategies

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Items 401–500 of 1,005

  1. Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer’s mouse model by controlling β-amyloid production
    Sandra Colié, Sara Sarroca, Rocío Palenzuela, Idoia García, Ander Matheu, Rubén Corpas, Carlos G. Dotti, Jose Antonio Esteban, Coral Sanfeliu, Ángel R. Nebreda · 2017 · Scientific Reports
  2. Ultrasound-Excited Protoporphyrin IX-Modified Multifunctional Nanoparticles as a Strong Inhibitor of Tau Phosphorylation and β-Amyloid Aggregation
    Mengmeng Xu, Hui Zhou, Yanan Liu, Jing Sun, Wenjie Xie, Ping Zhao, Jie Liu · 2018 · ACS Applied Materials & Interfaces
  3. Emerging roles of long non-coding RNAs in the pathogenesis of Alzheimer’s disease
    Francesca Cortini, Francesca Roma, Chiara Villa · 2019 · Ageing Research Reviews
  4. Advances of tooth‐derived stem cells in neural diseases treatments and nerve tissue regeneration
    Dianri Wang, Yuhao Wang, Weidong Tian, Jian Pan · 2019 · Cell Proliferation
  5. Pharmacodynamic and urinary metabolomics studies on the mechanism of Schisandra polysaccharide in the treatment of Alzheimer's disease
    Yuanyuan Liu, Zhongying Liu, Mengying Wei, Mingxin Hu, Kexin Yue, Rongbing Bi, Shan Zhai, Zifeng Pi, Fengrui Song, Zhiqiang Liu · 2018 · Food & Function
  6. Leonurine: From Gynecologic Medicine to Pleiotropic Agent
    Yunyun Li, Yikong Lin, Xinhua Liu, Li Wang, Min Yu, Da‐Jin Li, Yi Zhun Zhu, Meirong Du · 2019 · Chinese Journal of Integrative Medicine
  7. Ameliorative Effect of Necrosulfonamide in a Rat Model of Alzheimer’s Disease: Targeting Mixed Lineage Kinase Domain-like Protein-Mediated Necroptosis
    Tarek K. Motawi, Zeinab M. Abdel-Nasser, Nancy Nabil Shahin · 2020 · ACS Chemical Neuroscience
  8. Anti-dementia Activity of Nobiletin, a Citrus Flavonoid: A Review of Animal Studies
    Akira Nakajima, Yasushi Ohizumi, Kiyofumi Yamada · 2014 · Clinical Psychopharmacology and Neuroscience
  9. C-Glycosylflavones Alleviate Tau Phosphorylation and Amyloid Neurotoxicity through GSK3β Inhibition
    Zhibin Liang, Bei Zhang, Wei Su, Philip G. Williams, Qing X. Li · 2016 · ACS Chemical Neuroscience
  10. Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer’s Disease
    Mahar, Ian, Albuquerque, Marilia Silva, Mondragon-Rodriguez, Siddhartha, Cavanagh, Chelsea, Davoli, Maria Antonietta, Chabot, Jean-Guy, Williams, Sylvain, Mechawar, Naguib, Quirion, Rémi, Krantic, Slavica · 2017 · Frontiers in Aging Neuroscience
  11. Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways
    Christopher Böhm, F. Chen, Jean Sévalle, Seema Qamar, Roger B. Dodd, Y. Li, Gerold Schmitt‐Ulms, Paul E. Fraser, Peter St George‐Hyslop · 2015 · Molecular and Cellular Neuroscience
  12. Microbiome-derived indole-3-lactic acid reduces amyloidopathy through aryl-hydrocarbon receptor activation
    Hyun Kim, Eunkyung Lee, M.K. Park, Kyungchan Min, Yen Ngoc Diep, Jinhong Kim, Hyeok Ahn, Eulgi Lee, Sujeong Kim, Yunjae Kim et al. · 2024 · Brain Behavior and Immunity
  13. The G Protein‐Coupled Receptor 55 Ligand l ‐α‐Lysophosphatidylinositol Exerts Microglia‐Dependent Neuroprotection After Excitotoxic Lesion
    Sonja Kallendrusch, Stine Kremzow, Marcin Nowicki, Urszula Hohmann, Ria Winkelmann, Alexander Benz, Robert Kraft, Ingo Bechmann, Faramarz Dehghani, Marco Koch · 2013 · Glia
  14. Characterization of Young and Old Adult Brains: An EEG Functional Connectivity Analysis
    Bahar Moezzi, Latha Madhuri Pratti, Brenton G. Hordacre, Lynton J. Graetz, Carolyn F. Berryman, Louise M. Lavrencic, Michael C. Ridding, Hannah A. D. Keage, Mark D. McDonnell, Mitchell R. Goldsworthy · 2019 · Neuroscience
  15. Regulation of ADAM10 by miR-140-5p and potential relevance for Alzheimer's disease
    Rumana Akhter, Yvonne Y. Shao, McKenzie L. Shaw, Shane V. Formica, Maria Khrestian, James B. Leverenz, Lynn M. Bekris · 2017 · Neurobiology of Aging
  16. Evaluation of anti-amnesic effect of extracts of selected Ocimum species using in-vitro and in-vivo models
    Singh, Varinder, Kahol, Aditi, Singh, Inder Pal, Saraf, Isha, Shri, Richa · 2016 · Journal of Ethnopharmacology
  17. Evidence that the Human Innate Immune Peptide LL-37 may be a Binding Partner of Amyloid-β and Inhibitor of Fibril Assembly
    Ersilia De Lorenzi, Marcella Chiari, Raffaella Colombo, Marina Cretich, Laura Solá, Renzo Vanna, Paola Gagni, Federica Bisceglia, Carlo Morasso, Jennifer S Lin et al. · 2017 · Journal of Alzheimer s Disease
  18. N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer’s Disease
    Chenxi Du, Lei Wang, Qianwen Guan, Hongyu Yang, Tingkai Chen, Yijun Liu, Qihang Li, Weiping Lyu, Xin Lü, Ying Chen et al. · 2022 · Journal of Medicinal Chemistry
  19. Current Progress of Genetically Engineered Pig Models for Biomedical Research
    Gökhan Gün, Wilfried A. Kues · 2014 · BioResearch open access
  20. Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI
    Guillaume Bort, Sarah Catoen, Hélène Borderies, Adel Kebsi, Sébastien Ballet, Gaëlle Louin, Marc Port, Clotilde Ferroud · 2014 · European Journal of Medicinal Chemistry
  21. Triptolide treatment reduces Alzheimer’s disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD
    Qi Wang, Bing Xiao, Shuqin Cui, Hailong Song, Yanjing Qian, Lin Dong, Haiting An, Yanqiu Cui, Wenjing Zhang, Yi He et al. · 2014 · Disease Models & Mechanisms
  22. Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes
    Aris A. Polyzos, Amy Holt, Christopher Brown, Celica Glenn Cosme, Peter Wipf, Àlex Gómez-Marín, María del R. Castro, Sylvette Ayala‐Peña, Cynthia T. McMurray · 2016 · Human Molecular Genetics
  23. Aim for the core: suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration
    Kwadwo Opoku-Nsiah, Jason E. Gestwicki · 2018 · Translational research
  24. Amyloid beta soluble forms and plasminogen activation system in Alzheimer’s disease: Consequences on extracellular maturation of brain‐derived neurotrophic factor and therapeutic implications
    Francesco Angelucci, Kateřina Čechová, Richard Průša, Jakub Hort · 2018 · CNS Neuroscience & Therapeutics
  25. The exploration of novel Alzheimer’s therapeutic agents from the pool of FDA approved medicines using drug repositioning, enzyme inhibition and kinetic mechanism approaches
    Mubashir Hassan, Hussain Raza, Muhammad Athar Abbasi, Ahmed A. Moustafa, Sung‐Yum Seo · 2018 · Biomedicine & Pharmacotherapy
  26. Prospects for the application of mesenchymal stem cells in Alzheimer's disease treatment
    Forough Chakari-Khiavi, Sanam Dolati, Aref Chakari-Khiavi, Hossein Abbaszadeh, Leili Aghebati Maleki, Tannaz Pourlak, Amir Mehdizadeh, Mehdi Yousefi · 2019 · Life Sciences
  27. Hippocampal long‐term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G‐protein‐gated inwardly rectifying potassium channel activity
    Irene Sánchez‐Rodríguez, Souhail Djebari, Sara Temprano‐Carazo, David Vega‐Avelaira, Raquel Jiménez‐Herrera, Guillermo Iborra‐Lázaro, Javier Yajeya, Lydia Jiménez‐Díaz, Juan D. Navarro‐López · 2019 · Journal of Neurochemistry
  28. lncRNA SNHG1 Knockdown Alleviates Amyloid-β-Induced Neuronal Injury by Regulating ZNF217 via Sponging miR-361-3p in Alzheimer’s Disease
    Yiwen Gao, Nan Zhang, Chunmei Lv, Na Li, Xueqin Li, Weiwei Li · 2020 · Journal of Alzheimer s Disease
  29. Ferulic Acid Inhibits the Transition of Amyloid-β42 Monomers to Oligomers but Accelerates the Transition from Oligomers to Fibrils
    Lili Cui, Yuan Zhang, Hao Cao, Yan Wang, Teng Teng, Guoda Ma, You Li, Keshen Li, Yingjiu Zhang · 2013 · Journal of Alzheimer s Disease
  30. Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood–brain barrier model
    Hisham Qosa, Harry LeVine, Jeffrey N. Keller, Amal Kaddoumi · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  31. Molecular Basis of Substrate Recognition and Degradation by Human Presequence Protease
    John V. Lin King, Wenguang G. Liang, Kathryn P. Scherpelz, Alexander B. Schilling, Stephen C. Meredith, Wei‐Jen Tang · 2014 · Structure
  32. Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients
    Manja Lehmann, P. Ghosh, Catherine A. Madison, Anna Karydas, Giovanni Coppola, James P. O’Neil, Yadong Huang, Bruce L. Miller, William Jagust, Gil Dan Rabinovici · 2013 · Journal of Neurology Neurosurgery & Psychiatry
  33. Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease
    Soumitra Ghosh, Robert L. Geahlen · 2015 · EBioMedicine
  34. Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease
    Xiaodong Shi, Kai Sun, Rui Hu, Xiao-Ya Liu, Qiu‐Mei Hu, Xiaoyu Sun, Bin Yao, Nan Sun, Jing‐Ru Hao, Pan Wei et al. · 2016 · Journal of Neuroscience
  35. BACE1 inhibitory activity and molecular docking analysis of meroterpenoids from Sargassum serratifolium
    Su Hui Seong, Md Yousof Ali, Hyeung‐Rak Kim, Hyun Ah Jung, Jae Sue Choi · 2017 · Bioorganic & Medicinal Chemistry
  36. Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet
    Miaomiao Zhou, Lin Ding, Min Wen, Hongxia Che, Jiaqi Huang, Tiantian Zhang, Changhu Xue, Xiangzhao Mao, Yu-ming Wang · 2018 · The Journal of Nutritional Biochemistry
  37. Sleep and circadian rhythm disruption and stress intersect in Alzheimer's disease
    Trongha Phan, Roneil Gopal Malkani · 2018 · Neurobiology of Stress
  38. Chemokines in Alzheimer’s Disease: New Insights Into Prokineticins, Chemokine-Like Proteins
    Anna Rita Zuena, Paola Casolini, Roberta Lattanzi, Daniela Maftei · 2019 · Frontiers in Pharmacology
  39. Multilayered N-Glycoproteome Profiling Reveals Highly Heterogeneous and Dysregulated Protein N-Glycosylation Related to Alzheimer’s Disease
    Pan Fang, Juanjuan Xie, Shaoming Sang, Lei Zhang, Mingqi Liu, Lujie Yang, Yiteng Xu, Guoquan Yan, Jun Hu Yao, Xing Gao et al. · 2019 · Analytical Chemistry
  40. Geniposide Ameliorates Cognitive Deficits by Attenuating the Cholinergic Defect and Amyloidosis in Middle-Aged Alzheimer Model Mice
    Zhao, Chunhui, Zhang, Haijing, Li, Hang, Lv, Cui, Liu, Xiaoli, Li, Zhi, Xin, Wenfeng, Wang, Yongyan, Zhang, Wensheng · 2017 · Neuropharmacology
  41. Diagnostic Value of microRNA for Alzheimer’s Disease: A Systematic Review and Meta-Analysis
    Yong-Bo Hu, Chunming Li, Ning Song, Yang Zou, Sheng-Di Chen, Ru‐Jing Ren, Gang Wang · 2016 · Frontiers in Aging Neuroscience
  42. Treatment of beta amyloid 1–42 (Aβ1–42)-induced basal forebrain cholinergic damage by a non-classical estrogen signaling activator in vivo
    Andrea Kwakowsky, Kyoko Potapov, SooHyun Kim, Katie Peppercorn, Warren Perry Tate, István M. Ábrahám · 2016 · Scientific Reports
  43. Ghrelin in Alzheimer’s disease: Pathologic roles and therapeutic implications
    Seong Gak Jeon, Sang Bum Hong, Yunkwon Nam, Jungyeon Tae, Anji Yoo, Eun Ji Song, Kun Il Kim, Dongje Lee, Junyong Park, Sang Min Lee et al. · 2019 · Ageing Research Reviews
  44. The Interplay Between Beta-Amyloid 1–42 (Aβ1–42)-Induced Hippocampal Inflammatory Response, p-tau, Vascular Pathology, and Their Synergistic Contributions to Neuronal Death and Behavioral Deficits
    Beatriz Calvo‐Flores Guzmán, Tessa Elizabeth Chaffey, Thulani Hansika Palpagama, Sarah Waters, Jordi Boix, Warren Perry Tate, Katie Peppercorn, Michael Dragunow, Henry John Waldvogel, Richard L. M. Faull et al. · 2020 · Frontiers in Molecular Neuroscience
  45. History and Experience: A Survey of Traditional Chinese Medicine Treatment for Alzheimer′s Disease
    Ping Liu, Mingwang Kong, Shihe Yuan, Junfeng Liu, Ping Wang · 2014 · Evidence-based Complementary and Alternative Medicine
  46. Laminar and Dorsoventral Molecular Organization of the Medial Entorhinal Cortex Revealed by Large-scale Anatomical Analysis of Gene Expression
    Helen L. Ramsden, Gülşen Sürmeli, Steven McDonagh, Matthew F. Nolan · 2015 · PLoS Computational Biology
  47. Beta-Amyloid and Tau-Protein: Structure, Interaction, and Prion-Like Properties
    Olga G. Tatarnikova, М. А. Орлов, Natalia V. Bobkova · 2015 · Biochemistry (Moscow)
  48. Emerging drugs to reduce abnormal β-amyloid protein in Alzheimer’s disease patients
    Francesco Panza, Davide Seripa, Vincenzo Solfrizzi, Bruno Pietro Imbimbo, Madia Lozupone, Antonio Leo, Rodolfo Sardone, Gaetano Gagliardi, Lucia Lofano, Bianca C. Creanza et al. · 2016 · Expert Opinion on Emerging Drugs
  49. Cholinesterase and carboxylesterase inhibitors as pharmacological agents
    Галина Ф. Махаева, Елена Владимировна Рудакова, Надежда Владимировна Ковалева, Sofya V. Lushchekina, Natalia P. Boltneva, Alexey N. Proshin, Evgeny V. Shchegolkov, Yanina V. Burgart, В. И. Салоутин · 2019 · Russian Chemical Bulletin
  50. Characterization of a pectin from Lonicera japonica Thunb. and its inhibition effect on Aβ42 aggregation and promotion of neuritogenesis
    Liu, Qin, Fang, Jianping, Wang, Peipei, Du, Zhenyun, Li, Yanling, Wang, Shunchun, Ding, Kan · 2018 · International Journal of Biological Macromolecules
  51. Factors for predicting reversion from mild cognitive impairment to normal cognition: A meta‐analysis
    Huiping Xue, Ping Kang Hou, YongNan Li, Xin’e Mao, LinFeng Wu, Yongbing Liu · 2019 · International Journal of Geriatric Psychiatry
  52. The anesthetic sevoflurane induces tau trafficking from neurons to microglia
    Yuanlin Dong, Feng Liang, Lining Huang, Fang Fang, Guang Yang, Rudolph E. Tanzi, Yiying Zhang, Qimin Quan, Zhongcong Xie · 2021 · Communications Biology
  53. SIRT1 exerts protective effects by inhibiting endoplasmic reticulum stress and NF-κB signaling pathways
    Kaixuan Zhao, Haoyue Zhang, Dong Yang · 2024 · Frontiers in Cell and Developmental Biology
  54. Deep cervical lymphovenous anastomosis (LVA) for Alzheimer’s disease: microsurgical procedure in a prospective cohort study
    Jingyu Chen, Dawei Zhao, Yi Yin, Li Gui, Xin Chen, Xiaomei Wang, Pangbo Wang, Chenghai Zuo, Zhaopan Lai, Chong Li et al. · 2025 · International Journal of Surgery
  55. Semiquantitative proteomic analysis of human hippocampal tissues from Alzheimer’s disease and age-matched control brains
    Ilijana Begcevic, Hari Kosanam, Eduardo Martínez‐Morillo, Apostolos Dimitromanolakis, Phedias Diamandis, Uroš Kuzmanov, Lili‐Naz Hazrati, Eleftherios P. Diamandis · 2013 · Clinical Proteomics
  56. Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport
    Kyoko Chiba, Masahiko Araseki, Keisuke Nozawa, Keiko Furukori, Yoichi Araki, Takahide Matsushima, Tadashi Nakaya, Saori Hata, Yuhki Saito, Seiichi Uchida et al. · 2014 · Molecular Biology of the Cell
  57. Amyloid-β(25-35) Modulates the Expression of GirK and KCNQ Channel Genes in the Hippocampus
    Jennifer Mayordomo‐Cava, Javier Yajeya, Juan D. Navarro‐López, Lydia Jiménez‐Díaz · 2015 · PLoS ONE
  58. Dementia-related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits Aβ42 toxicity in Drosophila
    Helen Poska, Martin Haslbeck, Firoz Roshan Kurudenkandy, Erik Hermansson, Gefei Chen, George Kostallas, Axel Abelein, Henrik Biverstål, Sophie Crux, André Fisahn et al. · 2016 · Biochemical Journal
  59. Photoacoustic imaging of voltage responses beyond the optical diffusion limit
    Bin Rao, Ruiying Zhang, Lei Li, Jin‐Yu Shao, Lihong V. Wang · 2017 · Scientific Reports
  60. The Role of Mitochondrial Aldehyde Dehydrogenase 2 (ALDH2) in Neuropathology and Neurodegeneration.
    Che‐Hong Chen, Amit U. Joshi, Daria Mochly‐Rosen · 2016 · PubMed
  61. Electrochemical detection of Alzheimer's disease related substances in biofluids by silica nanochannel membrane modified glassy carbon electrodes
    Lin Zhou, Hao Ding, Fei Yan, Weiliang Guo, Bin Su · 2018 · The Analyst
  62. Telmisartan Protects Against Aluminum-Induced Alzheimer-like Pathological Changes in Rats
    Mona Khalifa, Marwa M. Safar, Rania M. Abdelsalam, Hala Fahmy Zaki · 2019 · Neurotoxicity Research
  63. The Role of Mitochondrial Impairment in Alzheimer´s Disease Neurodegeneration: The Tau Connection
    Rodrigo A. Quntanilla, Carola Tapia-Monsalves · 2020 · Current Neuropharmacology
  64. Glucose metabolism: A link between traumatic brain injury and Alzheimer’s disease
    Xiaojian Xu, Meng-Shi Yang, Bin Zhang, Fei Niu, Jinqian Dong, Baiyun Liu · 2020 · Chinese Journal of Traumatology
  65. Unambiguous Detection of Elevated Levels of Hypochlorous Acid in Double Transgenic AD Mouse Brain
    Samanta, Sourav, Govindaraju, Thimmaiah · 2019 · ACS Chemical Neuroscience
  66. Molecularly imprinted polymers for the recognition of biomarkers of certain neurodegenerative diseases
    Greta Pilvenyte, Vilma Ratautaitė, Raimonda Bogužaitė, Urtė Samukaitė-Bubnienė, Deivis Plaušinaitis, Almira Ramanavičienė, Mikhaël Bechelany, Arūnas Ramanavičius · 2023 · Journal of Pharmaceutical and Biomedical Analysis
  67. Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1
    Masaya Tachibana, Mitsuru Shinohara, Yu Yamazaki, Chia‐Chen Liu, Justin T. Rogers, Guojun Bu, Takahisa Kanekiyo · 2015 · Experimental Neurology
  68. Protective effects of kinetin against aluminum chloride and D-galactose induced cognitive impairment and oxidative damage in mouse
    Yunpeng Wei, Dan Liu, Yin Zheng, Honglian Li, Chaoshuang Hao, Wuqing Ouyang · 2017 · Brain Research Bulletin
  69. Synthesis, biological evaluation and molecular dynamic simulations of novel Benzofuran-tetrazole derivatives as potential agents against Alzheimer’s disease
    Pragati Kushwaha, Soobiya Fatima, Akanksha Upadhyay, Sampa Gupta, Sudha Bhagwati, Tanvi Baghel, Mohammad Imran Siddiqi, Aamir Nazir, Koneni V. Sashidhara · 2018 · Bioorganic & Medicinal Chemistry Letters
  70. Interleukin-4 affects microglial autophagic flux
    Run-Hong Tang, Rui-Qun Qi, Hua-Yan Liu · 2019 · Neural Regeneration Research
  71. Highly specific detection of Aβ oligomers in early Alzheimer's disease by a near-infrared fluorescent probe with a “V-shaped” spatial conformation
    Jian Yang, Fantian Zeng, Xiaofang Li, Chongzhao Ran, Yungen Xu, Yuyan Li · 2019 · Chemical Communications
  72. Prevention of Cognitive Decline in Alzheimer’s Disease by Novel Antioxidative Supplements
    Koh Tadokoro, Yasuyuki Ohta, Haruhiko Inufusa, Alan Foo Nyuk Loon, Koji Abe · 2020 · International Journal of Molecular Sciences
  73. Ferulic Acid Ameliorates Alzheimer's Disease-like Pathology and Repairs Cognitive Decline by Preventing Capillary Hypofunction in APP/PS1 Mice
    Ni-Ya Wang, Jinnan Li, Weilin Liu, Qi Huang, Wenxing Li, Yahong Tan, Fang Liu, Zihua Song, Meng-Yue Wang, Ning Xie et al. · 2021 · Neurotherapeutics
  74. Metabolic Disturbances in Diseases with Neurological Involvement
    João M. N. Duarte · 2014 · Aging and Disease
  75. In Vivo Screening of Traditional Medicinal Plants for Neuroprotective Activity against Aβ42 Cytotoxicity by Using Drosophila Models of Alzheimer’s Disease
    Quan Feng Liu, Jang Ho Lee, Young‐Mi Kim, Soojin Lee, Yoon Ki Hong, Soojin Hwang, Youngje Oh, Kyung‐Ho Lee, Hye Sup Yun, Im‐Soon Lee et al. · 2015 · Biological and Pharmaceutical Bulletin
  76. Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling
    Lucy Crompton, Meg L. Byrne, Hannah Taylor, Talitha L. Kerrigan, Gilles Bru‐Mercier, Jennifer L. Badger, Peter A. Barbuti, Jihoon Jo, Sue J. Tyler, Shelley Jane Allen et al. · 2013 · Stem Cell Research
  77. Sex and gonadal hormones in mouse models of Alzheimer’s disease: what is relevant to the human condition?
    Dena B. Dubal, Lauren Broestl, Kurtresha Worden · 2012 · Biology of Sex Differences
  78. Epigenetic Regulation of Memory by Acetylation and Methylation of Chromatin: Implications in Neurological Disorders, Aging, and Addiction
    Nilkantha Sen · 2014 · NeuroMolecular Medicine
  79. Cross-species translation of the Morris maze for Alzheimer’s disease
    Katherine L. Possin, Pascal E. Sanchez, Clifford Anderson-Bergman, Roland Fernandez, Geoffrey A. Kerchner, Erica T. Johnson, Allyson Davis, Iris Lo, Nicholas T. Bott, Thomas Kiely et al. · 2016 · Journal of Clinical Investigation
  80. Berberine modulates amyloid-β peptide generation by activating AMP-activated protein kinase
    Haijing Zhang, Chunhui Zhao, Guoqiong Cao, Limin Guo, Shuai Zhang, Yuexia Liang, Chunxia Qin, Ping Su, Hang Li, Wensheng Zhang · 2017 · Neuropharmacology
  81. Prenatal exposure to bisphenol A alters the transcriptome-interactome profiles of genes associated with Alzheimer’s disease in the offspring hippocampus
    Suporn Sukjamnong, Surangrat Thongkorn, Songphon Kanlayaprasit, Thanit Saeliw, Kanlayaphat Hussem, Watis Warayanon, Valerie Wailin Hu, Tewin Tencomnao, Tewarit Sarachana · 2020 · Scientific Reports
  82. Protective effects of ginsenoside Rg2 against memory impairment and neuronal death induced by Aβ25-35 in rats
    Jing Cui, Rui Shan, Yanqi Cao, Yifa Zhou, Chunming Liu, Yuying Fan · 2020 · Journal of Ethnopharmacology
  83. New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer’s Disease Treatment
    Галина Ф. Махаева, Надежда Владимировна Ковалева, Елена Владимировна Рудакова, Natalia P. Boltneva, Sofya V. Lushchekina, Irina I. Faingold, Darya A. Poletaeva, Yu. V. Soldatova, Raisa A. Kotelnikova, Igor V. Serkov et al. · 2020 · Molecules
  84. Lipid metabolism in Alzheimer’s disease
    Zhu, Tian-Bi, Zhang, Zhao, Luo, Piao, Wang, Sha-Sha, Peng, Ye, Chu, Shi-Feng, Chen, Nai-Hong · 2019 · Brain Research Bulletin
  85. Metabolic perspective of astrocyte dysfunction in Alzheimer's disease and type 2 diabetes brains
    Zheng Shen, Zhengyang Li, Mengting Yu, Kai-Leng Tan, Si Xuan Chen · 2023 · Biomedicine & Pharmacotherapy
  86. The journey of boswellic acids from synthesis to pharmacological activities
    Ehab A. Ragab, Mohammed F. Abdelwahab, Ahmed Soliman Doghish, Rania M. Salama, Nermin Eissa, Samar F. Darwish · 2023 · Naunyn-Schmiedeberg s Archives of Pharmacology
  87. Insulin/IGF Signaling-Related Gene Expression in the Brain of a Sporadic Alzheimer's Disease Monkey Model Induced by Intracerebroventricular Injection of Streptozotocin
    Youngjeon Lee, Young-Hyun Kim, Sang-Je Park, Jae‐Won Huh, Sang‐Hyun Kim, Sun‐Uk Kim, Jisu Kim, Kang-Jin Jeong, Kyoungmin Lee, Yonggeun Hong et al. · 2013 · Journal of Alzheimer s Disease
  88. Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders
    Martin Hofmann‐Apitius, Gordon Ball, Stephan Gebel, Shweta Bagewadi, Bernard de Bono, Reinhard Schneider, Matt Page, Alpha Tom Kodamullil, Erfan Younesi, Christian Ebeling et al. · 2015 · International Journal of Molecular Sciences
  89. Histone acetylation in neuronal (dys)function
    Emilie M. Bonnaud, Elsa Suberbielle, Cécile E. Malnou · 2016 · BioMolecular Concepts
  90. Artificial neural networks in the discrimination of Alzheimer's disease using biomarkers data
    Almir Aljović, Almir Badnjević, Lejla Gurbeta · 2016 · Mediterranean Conference on Embedded Computing (MECO)
  91. Caspase-3-Dependent Proteolytic Cleavage of Tau Causes Neurofibrillary Tangles and Results in Cognitive Impairment During Normal Aging
    Means, John C., Gerdes, Bryan C., Kaja, Simon, Sumien, Nathalie, Payne, Andrew J., Stark, Danny A., Borden, Priscilla K., Price, Jeffrey L., Koulen, Peter · 2016 · Neurochemical Research
  92. Pig models of neurodegenerative disorders: Utilization in cell replacement‐based preclinical safety and efficacy studies
    Dáša Bohačiaková, Marián Hruška-Plocháň, Carsten Reidies Bjarkam, Jens Christian Hedemann Sørensen, Miles Gregory Cunningham, David Weingarten, Joseph D. Ciacci, Štefan Juhás, Jana Juhásová, Jan Motlík et al. · 2014 · The Journal of Comparative Neurology
  93. Genomic Editing Tools to Model Human Diseases with Isogenic Pluripotent Stem Cells
    Huen Suk Kim, Jeffrey M. Bernitz, Dung‐Fang Lee, Ihor R. Lemischka · 2014 · Stem Cells and Development
  94. Magnetite-Amyloid-β deteriorates activity and functional organization in an in vitro model for Alzheimer’s disease
    Sara Teller, Islam Bogachan Tahirbegi, Mònica Mir, Josep Samitier, Jordi Soriano · 2015 · Scientific Reports
  95. Icariin decreases both APP and Aβ levels and increases neurogenesis in the brain of Tg2576 mice
    F. Li, Hongxin Dong, Qihai Gong, Qin Wu, F. Jin, Jingshan Shi · 2015 · Neuroscience
  96. Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus
    Yue Tian, Keyan Chen, Lidan Liu, Yun-xia Dong, Ping Zhao, Shanbin Guo · 2018 · Mediators of Inflammation
  97. Identification of Alzheimer’s Disease Autoantibodies and Their Target Biomarkers by Phage Microarrays
    Pablo San Segundo‐Acosta, Ana Montero‐Calle, Manuel Fuentes, Alberto Rábano, Mayte Villalba, Rodrigo Barderas · 2019 · Journal of Proteome Research
  98. New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer’s Disease Treatment
    Makhaeva, Galina F., Kovaleva, Nadezhda V., Boltneva, Natalia P., Lushchekina, Sofya V., Astakhova, Tatiana Yu., Rudakova, Elena V., Proshin, Alexey N., Serkov, Igor V., Radchenko, Eugene V., Palyulin, Vladimir A. et al. · 2020 · Molecules
  99. Apolipoprotein E: Remarkable Protein Sheds Light on Cardiovascular and Neurological Diseases
    Mahley, Robert W · 2017 · Clinical Chemistry
  100. In Vivo Chimeric Alzheimer’s Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons
    Najm, Ramsey, Zalocusky, Kelly A., Zilberter, Misha, Yoon, Seo Yeon, Hao, Yanxia, Koutsodendris, Nicole, Nelson, Maxine, Rao, Antara, Taubes, Alice, Jones, Emily A. et al. · 2020 · Cell Reports