Alzheimer Mechanisms and Therapeutic Strategies
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Items 401–500 of 1,005
- Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer’s mouse model by controlling β-amyloid productionSandra Colié, Sara Sarroca, Rocío Palenzuela, Idoia García, Ander Matheu, Rubén Corpas, Carlos G. Dotti, Jose Antonio Esteban, Coral Sanfeliu, Ángel R. Nebreda · 2017 · Scientific Reports
- Ultrasound-Excited Protoporphyrin IX-Modified Multifunctional Nanoparticles as a Strong Inhibitor of Tau Phosphorylation and β-Amyloid AggregationMengmeng Xu, Hui Zhou, Yanan Liu, Jing Sun, Wenjie Xie, Ping Zhao, Jie Liu · 2018 · ACS Applied Materials & Interfaces
- Emerging roles of long non-coding RNAs in the pathogenesis of Alzheimer’s diseaseFrancesca Cortini, Francesca Roma, Chiara Villa · 2019 · Ageing Research Reviews
- Advances of tooth‐derived stem cells in neural diseases treatments and nerve tissue regenerationDianri Wang, Yuhao Wang, Weidong Tian, Jian Pan · 2019 · Cell Proliferation
- Pharmacodynamic and urinary metabolomics studies on the mechanism of Schisandra polysaccharide in the treatment of Alzheimer's diseaseYuanyuan Liu, Zhongying Liu, Mengying Wei, Mingxin Hu, Kexin Yue, Rongbing Bi, Shan Zhai, Zifeng Pi, Fengrui Song, Zhiqiang Liu · 2018 · Food & Function
- Leonurine: From Gynecologic Medicine to Pleiotropic AgentYunyun Li, Yikong Lin, Xinhua Liu, Li Wang, Min Yu, Da‐Jin Li, Yi Zhun Zhu, Meirong Du · 2019 · Chinese Journal of Integrative Medicine
- Ameliorative Effect of Necrosulfonamide in a Rat Model of Alzheimer’s Disease: Targeting Mixed Lineage Kinase Domain-like Protein-Mediated NecroptosisTarek K. Motawi, Zeinab M. Abdel-Nasser, Nancy Nabil Shahin · 2020 · ACS Chemical Neuroscience
- Anti-dementia Activity of Nobiletin, a Citrus Flavonoid: A Review of Animal StudiesAkira Nakajima, Yasushi Ohizumi, Kiyofumi Yamada · 2014 · Clinical Psychopharmacology and Neuroscience
- C-Glycosylflavones Alleviate Tau Phosphorylation and Amyloid Neurotoxicity through GSK3β InhibitionZhibin Liang, Bei Zhang, Wei Su, Philip G. Williams, Qing X. Li · 2016 · ACS Chemical Neuroscience
- Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer’s DiseaseMahar, Ian, Albuquerque, Marilia Silva, Mondragon-Rodriguez, Siddhartha, Cavanagh, Chelsea, Davoli, Maria Antonietta, Chabot, Jean-Guy, Williams, Sylvain, Mechawar, Naguib, Quirion, Rémi, Krantic, Slavica · 2017 · Frontiers in Aging Neuroscience
- Current and future implications of basic and translational research on amyloid-β peptide production and removal pathwaysChristopher Böhm, F. Chen, Jean Sévalle, Seema Qamar, Roger B. Dodd, Y. Li, Gerold Schmitt‐Ulms, Paul E. Fraser, Peter St George‐Hyslop · 2015 · Molecular and Cellular Neuroscience
- Microbiome-derived indole-3-lactic acid reduces amyloidopathy through aryl-hydrocarbon receptor activationHyun Kim, Eunkyung Lee, M.K. Park, Kyungchan Min, Yen Ngoc Diep, Jinhong Kim, Hyeok Ahn, Eulgi Lee, Sujeong Kim, Yunjae Kim et al. · 2024 · Brain Behavior and Immunity
- The G Protein‐Coupled Receptor 55 Ligand l ‐α‐Lysophosphatidylinositol Exerts Microglia‐Dependent Neuroprotection After Excitotoxic LesionSonja Kallendrusch, Stine Kremzow, Marcin Nowicki, Urszula Hohmann, Ria Winkelmann, Alexander Benz, Robert Kraft, Ingo Bechmann, Faramarz Dehghani, Marco Koch · 2013 · Glia
- Characterization of Young and Old Adult Brains: An EEG Functional Connectivity AnalysisBahar Moezzi, Latha Madhuri Pratti, Brenton G. Hordacre, Lynton J. Graetz, Carolyn F. Berryman, Louise M. Lavrencic, Michael C. Ridding, Hannah A. D. Keage, Mark D. McDonnell, Mitchell R. Goldsworthy · 2019 · Neuroscience
- Regulation of ADAM10 by miR-140-5p and potential relevance for Alzheimer's diseaseRumana Akhter, Yvonne Y. Shao, McKenzie L. Shaw, Shane V. Formica, Maria Khrestian, James B. Leverenz, Lynn M. Bekris · 2017 · Neurobiology of Aging
- Evaluation of anti-amnesic effect of extracts of selected Ocimum species using in-vitro and in-vivo modelsSingh, Varinder, Kahol, Aditi, Singh, Inder Pal, Saraf, Isha, Shri, Richa · 2016 · Journal of Ethnopharmacology
- Evidence that the Human Innate Immune Peptide LL-37 may be a Binding Partner of Amyloid-β and Inhibitor of Fibril AssemblyErsilia De Lorenzi, Marcella Chiari, Raffaella Colombo, Marina Cretich, Laura Solá, Renzo Vanna, Paola Gagni, Federica Bisceglia, Carlo Morasso, Jennifer S Lin et al. · 2017 · Journal of Alzheimer s Disease
- N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer’s DiseaseChenxi Du, Lei Wang, Qianwen Guan, Hongyu Yang, Tingkai Chen, Yijun Liu, Qihang Li, Weiping Lyu, Xin Lü, Ying Chen et al. · 2022 · Journal of Medicinal Chemistry
- Current Progress of Genetically Engineered Pig Models for Biomedical ResearchGökhan Gün, Wilfried A. Kues · 2014 · BioResearch open access
- Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRIGuillaume Bort, Sarah Catoen, Hélène Borderies, Adel Kebsi, Sébastien Ballet, Gaëlle Louin, Marc Port, Clotilde Ferroud · 2014 · European Journal of Medicinal Chemistry
- Triptolide treatment reduces Alzheimer’s disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of ADQi Wang, Bing Xiao, Shuqin Cui, Hailong Song, Yanjing Qian, Lin Dong, Haiting An, Yanqiu Cui, Wenjing Zhang, Yi He et al. · 2014 · Disease Models & Mechanisms
- Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypesAris A. Polyzos, Amy Holt, Christopher Brown, Celica Glenn Cosme, Peter Wipf, Àlex Gómez-Marín, María del R. Castro, Sylvette Ayala‐Peña, Cynthia T. McMurray · 2016 · Human Molecular Genetics
- Aim for the core: suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegenerationKwadwo Opoku-Nsiah, Jason E. Gestwicki · 2018 · Translational research
- Amyloid beta soluble forms and plasminogen activation system in Alzheimer’s disease: Consequences on extracellular maturation of brain‐derived neurotrophic factor and therapeutic implicationsFrancesco Angelucci, Kateřina Čechová, Richard Průša, Jakub Hort · 2018 · CNS Neuroscience & Therapeutics
- The exploration of novel Alzheimer’s therapeutic agents from the pool of FDA approved medicines using drug repositioning, enzyme inhibition and kinetic mechanism approachesMubashir Hassan, Hussain Raza, Muhammad Athar Abbasi, Ahmed A. Moustafa, Sung‐Yum Seo · 2018 · Biomedicine & Pharmacotherapy
- Prospects for the application of mesenchymal stem cells in Alzheimer's disease treatmentForough Chakari-Khiavi, Sanam Dolati, Aref Chakari-Khiavi, Hossein Abbaszadeh, Leili Aghebati Maleki, Tannaz Pourlak, Amir Mehdizadeh, Mehdi Yousefi · 2019 · Life Sciences
- Hippocampal long‐term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G‐protein‐gated inwardly rectifying potassium channel activityIrene Sánchez‐Rodríguez, Souhail Djebari, Sara Temprano‐Carazo, David Vega‐Avelaira, Raquel Jiménez‐Herrera, Guillermo Iborra‐Lázaro, Javier Yajeya, Lydia Jiménez‐Díaz, Juan D. Navarro‐López · 2019 · Journal of Neurochemistry
- lncRNA SNHG1 Knockdown Alleviates Amyloid-β-Induced Neuronal Injury by Regulating ZNF217 via Sponging miR-361-3p in Alzheimer’s DiseaseYiwen Gao, Nan Zhang, Chunmei Lv, Na Li, Xueqin Li, Weiwei Li · 2020 · Journal of Alzheimer s Disease
- Ferulic Acid Inhibits the Transition of Amyloid-β42 Monomers to Oligomers but Accelerates the Transition from Oligomers to FibrilsLili Cui, Yuan Zhang, Hao Cao, Yan Wang, Teng Teng, Guoda Ma, You Li, Keshen Li, Yingjiu Zhang · 2013 · Journal of Alzheimer s Disease
- Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood–brain barrier modelHisham Qosa, Harry LeVine, Jeffrey N. Keller, Amal Kaddoumi · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Molecular Basis of Substrate Recognition and Degradation by Human Presequence ProteaseJohn V. Lin King, Wenguang G. Liang, Kathryn P. Scherpelz, Alexander B. Schilling, Stephen C. Meredith, Wei‐Jen Tang · 2014 · Structure
- Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patientsManja Lehmann, P. Ghosh, Catherine A. Madison, Anna Karydas, Giovanni Coppola, James P. O’Neil, Yadong Huang, Bruce L. Miller, William Jagust, Gil Dan Rabinovici · 2013 · Journal of Neurology Neurosurgery & Psychiatry
- Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's DiseaseSoumitra Ghosh, Robert L. Geahlen · 2015 · EBioMedicine
- Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's DiseaseXiaodong Shi, Kai Sun, Rui Hu, Xiao-Ya Liu, Qiu‐Mei Hu, Xiaoyu Sun, Bin Yao, Nan Sun, Jing‐Ru Hao, Pan Wei et al. · 2016 · Journal of Neuroscience
- BACE1 inhibitory activity and molecular docking analysis of meroterpenoids from Sargassum serratifoliumSu Hui Seong, Md Yousof Ali, Hyeung‐Rak Kim, Hyun Ah Jung, Jae Sue Choi · 2017 · Bioorganic & Medicinal Chemistry
- Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat dietMiaomiao Zhou, Lin Ding, Min Wen, Hongxia Che, Jiaqi Huang, Tiantian Zhang, Changhu Xue, Xiangzhao Mao, Yu-ming Wang · 2018 · The Journal of Nutritional Biochemistry
- Sleep and circadian rhythm disruption and stress intersect in Alzheimer's diseaseTrongha Phan, Roneil Gopal Malkani · 2018 · Neurobiology of Stress
- Chemokines in Alzheimer’s Disease: New Insights Into Prokineticins, Chemokine-Like ProteinsAnna Rita Zuena, Paola Casolini, Roberta Lattanzi, Daniela Maftei · 2019 · Frontiers in Pharmacology
- Multilayered N-Glycoproteome Profiling Reveals Highly Heterogeneous and Dysregulated Protein N-Glycosylation Related to Alzheimer’s DiseasePan Fang, Juanjuan Xie, Shaoming Sang, Lei Zhang, Mingqi Liu, Lujie Yang, Yiteng Xu, Guoquan Yan, Jun Hu Yao, Xing Gao et al. · 2019 · Analytical Chemistry
- Geniposide Ameliorates Cognitive Deficits by Attenuating the Cholinergic Defect and Amyloidosis in Middle-Aged Alzheimer Model MiceZhao, Chunhui, Zhang, Haijing, Li, Hang, Lv, Cui, Liu, Xiaoli, Li, Zhi, Xin, Wenfeng, Wang, Yongyan, Zhang, Wensheng · 2017 · Neuropharmacology
- Diagnostic Value of microRNA for Alzheimer’s Disease: A Systematic Review and Meta-AnalysisYong-Bo Hu, Chunming Li, Ning Song, Yang Zou, Sheng-Di Chen, Ru‐Jing Ren, Gang Wang · 2016 · Frontiers in Aging Neuroscience
- Treatment of beta amyloid 1–42 (Aβ1–42)-induced basal forebrain cholinergic damage by a non-classical estrogen signaling activator in vivoAndrea Kwakowsky, Kyoko Potapov, SooHyun Kim, Katie Peppercorn, Warren Perry Tate, István M. Ábrahám · 2016 · Scientific Reports
- Ghrelin in Alzheimer’s disease: Pathologic roles and therapeutic implicationsSeong Gak Jeon, Sang Bum Hong, Yunkwon Nam, Jungyeon Tae, Anji Yoo, Eun Ji Song, Kun Il Kim, Dongje Lee, Junyong Park, Sang Min Lee et al. · 2019 · Ageing Research Reviews
- The Interplay Between Beta-Amyloid 1–42 (Aβ1–42)-Induced Hippocampal Inflammatory Response, p-tau, Vascular Pathology, and Their Synergistic Contributions to Neuronal Death and Behavioral DeficitsBeatriz Calvo‐Flores Guzmán, Tessa Elizabeth Chaffey, Thulani Hansika Palpagama, Sarah Waters, Jordi Boix, Warren Perry Tate, Katie Peppercorn, Michael Dragunow, Henry John Waldvogel, Richard L. M. Faull et al. · 2020 · Frontiers in Molecular Neuroscience
- History and Experience: A Survey of Traditional Chinese Medicine Treatment for Alzheimer′s DiseasePing Liu, Mingwang Kong, Shihe Yuan, Junfeng Liu, Ping Wang · 2014 · Evidence-based Complementary and Alternative Medicine
- Laminar and Dorsoventral Molecular Organization of the Medial Entorhinal Cortex Revealed by Large-scale Anatomical Analysis of Gene ExpressionHelen L. Ramsden, Gülşen Sürmeli, Steven McDonagh, Matthew F. Nolan · 2015 · PLoS Computational Biology
- Beta-Amyloid and Tau-Protein: Structure, Interaction, and Prion-Like PropertiesOlga G. Tatarnikova, М. А. Орлов, Natalia V. Bobkova · 2015 · Biochemistry (Moscow)
- Emerging drugs to reduce abnormal β-amyloid protein in Alzheimer’s disease patientsFrancesco Panza, Davide Seripa, Vincenzo Solfrizzi, Bruno Pietro Imbimbo, Madia Lozupone, Antonio Leo, Rodolfo Sardone, Gaetano Gagliardi, Lucia Lofano, Bianca C. Creanza et al. · 2016 · Expert Opinion on Emerging Drugs
- Cholinesterase and carboxylesterase inhibitors as pharmacological agentsГалина Ф. Махаева, Елена Владимировна Рудакова, Надежда Владимировна Ковалева, Sofya V. Lushchekina, Natalia P. Boltneva, Alexey N. Proshin, Evgeny V. Shchegolkov, Yanina V. Burgart, В. И. Салоутин · 2019 · Russian Chemical Bulletin
- Characterization of a pectin from Lonicera japonica Thunb. and its inhibition effect on Aβ42 aggregation and promotion of neuritogenesisLiu, Qin, Fang, Jianping, Wang, Peipei, Du, Zhenyun, Li, Yanling, Wang, Shunchun, Ding, Kan · 2018 · International Journal of Biological Macromolecules
- Factors for predicting reversion from mild cognitive impairment to normal cognition: A meta‐analysisHuiping Xue, Ping Kang Hou, YongNan Li, Xin’e Mao, LinFeng Wu, Yongbing Liu · 2019 · International Journal of Geriatric Psychiatry
- The anesthetic sevoflurane induces tau trafficking from neurons to microgliaYuanlin Dong, Feng Liang, Lining Huang, Fang Fang, Guang Yang, Rudolph E. Tanzi, Yiying Zhang, Qimin Quan, Zhongcong Xie · 2021 · Communications Biology
- SIRT1 exerts protective effects by inhibiting endoplasmic reticulum stress and NF-κB signaling pathwaysKaixuan Zhao, Haoyue Zhang, Dong Yang · 2024 · Frontiers in Cell and Developmental Biology
- Deep cervical lymphovenous anastomosis (LVA) for Alzheimer’s disease: microsurgical procedure in a prospective cohort studyJingyu Chen, Dawei Zhao, Yi Yin, Li Gui, Xin Chen, Xiaomei Wang, Pangbo Wang, Chenghai Zuo, Zhaopan Lai, Chong Li et al. · 2025 · International Journal of Surgery
- Semiquantitative proteomic analysis of human hippocampal tissues from Alzheimer’s disease and age-matched control brainsIlijana Begcevic, Hari Kosanam, Eduardo Martínez‐Morillo, Apostolos Dimitromanolakis, Phedias Diamandis, Uroš Kuzmanov, Lili‐Naz Hazrati, Eleftherios P. Diamandis · 2013 · Clinical Proteomics
- Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transportKyoko Chiba, Masahiko Araseki, Keisuke Nozawa, Keiko Furukori, Yoichi Araki, Takahide Matsushima, Tadashi Nakaya, Saori Hata, Yuhki Saito, Seiichi Uchida et al. · 2014 · Molecular Biology of the Cell
- Amyloid-β(25-35) Modulates the Expression of GirK and KCNQ Channel Genes in the HippocampusJennifer Mayordomo‐Cava, Javier Yajeya, Juan D. Navarro‐López, Lydia Jiménez‐Díaz · 2015 · PLoS ONE
- Dementia-related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits Aβ42 toxicity in DrosophilaHelen Poska, Martin Haslbeck, Firoz Roshan Kurudenkandy, Erik Hermansson, Gefei Chen, George Kostallas, Axel Abelein, Henrik Biverstål, Sophie Crux, André Fisahn et al. · 2016 · Biochemical Journal
- Photoacoustic imaging of voltage responses beyond the optical diffusion limitBin Rao, Ruiying Zhang, Lei Li, Jin‐Yu Shao, Lihong V. Wang · 2017 · Scientific Reports
- The Role of Mitochondrial Aldehyde Dehydrogenase 2 (ALDH2) in Neuropathology and Neurodegeneration.Che‐Hong Chen, Amit U. Joshi, Daria Mochly‐Rosen · 2016 · PubMed
- Electrochemical detection of Alzheimer's disease related substances in biofluids by silica nanochannel membrane modified glassy carbon electrodesLin Zhou, Hao Ding, Fei Yan, Weiliang Guo, Bin Su · 2018 · The Analyst
- Telmisartan Protects Against Aluminum-Induced Alzheimer-like Pathological Changes in RatsMona Khalifa, Marwa M. Safar, Rania M. Abdelsalam, Hala Fahmy Zaki · 2019 · Neurotoxicity Research
- The Role of Mitochondrial Impairment in Alzheimer´s Disease Neurodegeneration: The Tau ConnectionRodrigo A. Quntanilla, Carola Tapia-Monsalves · 2020 · Current Neuropharmacology
- Glucose metabolism: A link between traumatic brain injury and Alzheimer’s diseaseXiaojian Xu, Meng-Shi Yang, Bin Zhang, Fei Niu, Jinqian Dong, Baiyun Liu · 2020 · Chinese Journal of Traumatology
- Unambiguous Detection of Elevated Levels of Hypochlorous Acid in Double Transgenic AD Mouse BrainSamanta, Sourav, Govindaraju, Thimmaiah · 2019 · ACS Chemical Neuroscience
- Molecularly imprinted polymers for the recognition of biomarkers of certain neurodegenerative diseasesGreta Pilvenyte, Vilma Ratautaitė, Raimonda Bogužaitė, Urtė Samukaitė-Bubnienė, Deivis Plaušinaitis, Almira Ramanavičienė, Mikhaël Bechelany, Arūnas Ramanavičius · 2023 · Journal of Pharmaceutical and Biomedical Analysis
- Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1Masaya Tachibana, Mitsuru Shinohara, Yu Yamazaki, Chia‐Chen Liu, Justin T. Rogers, Guojun Bu, Takahisa Kanekiyo · 2015 · Experimental Neurology
- Protective effects of kinetin against aluminum chloride and D-galactose induced cognitive impairment and oxidative damage in mouseYunpeng Wei, Dan Liu, Yin Zheng, Honglian Li, Chaoshuang Hao, Wuqing Ouyang · 2017 · Brain Research Bulletin
- Synthesis, biological evaluation and molecular dynamic simulations of novel Benzofuran-tetrazole derivatives as potential agents against Alzheimer’s diseasePragati Kushwaha, Soobiya Fatima, Akanksha Upadhyay, Sampa Gupta, Sudha Bhagwati, Tanvi Baghel, Mohammad Imran Siddiqi, Aamir Nazir, Koneni V. Sashidhara · 2018 · Bioorganic & Medicinal Chemistry Letters
- Interleukin-4 affects microglial autophagic fluxRun-Hong Tang, Rui-Qun Qi, Hua-Yan Liu · 2019 · Neural Regeneration Research
- Highly specific detection of Aβ oligomers in early Alzheimer's disease by a near-infrared fluorescent probe with a “V-shaped” spatial conformationJian Yang, Fantian Zeng, Xiaofang Li, Chongzhao Ran, Yungen Xu, Yuyan Li · 2019 · Chemical Communications
- Prevention of Cognitive Decline in Alzheimer’s Disease by Novel Antioxidative SupplementsKoh Tadokoro, Yasuyuki Ohta, Haruhiko Inufusa, Alan Foo Nyuk Loon, Koji Abe · 2020 · International Journal of Molecular Sciences
- Ferulic Acid Ameliorates Alzheimer's Disease-like Pathology and Repairs Cognitive Decline by Preventing Capillary Hypofunction in APP/PS1 MiceNi-Ya Wang, Jinnan Li, Weilin Liu, Qi Huang, Wenxing Li, Yahong Tan, Fang Liu, Zihua Song, Meng-Yue Wang, Ning Xie et al. · 2021 · Neurotherapeutics
- Metabolic Disturbances in Diseases with Neurological InvolvementJoão M. N. Duarte · 2014 · Aging and Disease
- In Vivo Screening of Traditional Medicinal Plants for Neuroprotective Activity against Aβ42 Cytotoxicity by Using Drosophila Models of Alzheimer’s DiseaseQuan Feng Liu, Jang Ho Lee, Young‐Mi Kim, Soojin Lee, Yoon Ki Hong, Soojin Hwang, Youngje Oh, Kyung‐Ho Lee, Hye Sup Yun, Im‐Soon Lee et al. · 2015 · Biological and Pharmaceutical Bulletin
- Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signalingLucy Crompton, Meg L. Byrne, Hannah Taylor, Talitha L. Kerrigan, Gilles Bru‐Mercier, Jennifer L. Badger, Peter A. Barbuti, Jihoon Jo, Sue J. Tyler, Shelley Jane Allen et al. · 2013 · Stem Cell Research
- Sex and gonadal hormones in mouse models of Alzheimer’s disease: what is relevant to the human condition?Dena B. Dubal, Lauren Broestl, Kurtresha Worden · 2012 · Biology of Sex Differences
- Epigenetic Regulation of Memory by Acetylation and Methylation of Chromatin: Implications in Neurological Disorders, Aging, and AddictionNilkantha Sen · 2014 · NeuroMolecular Medicine
- Cross-species translation of the Morris maze for Alzheimer’s diseaseKatherine L. Possin, Pascal E. Sanchez, Clifford Anderson-Bergman, Roland Fernandez, Geoffrey A. Kerchner, Erica T. Johnson, Allyson Davis, Iris Lo, Nicholas T. Bott, Thomas Kiely et al. · 2016 · Journal of Clinical Investigation
- Berberine modulates amyloid-β peptide generation by activating AMP-activated protein kinaseHaijing Zhang, Chunhui Zhao, Guoqiong Cao, Limin Guo, Shuai Zhang, Yuexia Liang, Chunxia Qin, Ping Su, Hang Li, Wensheng Zhang · 2017 · Neuropharmacology
- Prenatal exposure to bisphenol A alters the transcriptome-interactome profiles of genes associated with Alzheimer’s disease in the offspring hippocampusSuporn Sukjamnong, Surangrat Thongkorn, Songphon Kanlayaprasit, Thanit Saeliw, Kanlayaphat Hussem, Watis Warayanon, Valerie Wailin Hu, Tewin Tencomnao, Tewarit Sarachana · 2020 · Scientific Reports
- Protective effects of ginsenoside Rg2 against memory impairment and neuronal death induced by Aβ25-35 in ratsJing Cui, Rui Shan, Yanqi Cao, Yifa Zhou, Chunming Liu, Yuying Fan · 2020 · Journal of Ethnopharmacology
- New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer’s Disease TreatmentГалина Ф. Махаева, Надежда Владимировна Ковалева, Елена Владимировна Рудакова, Natalia P. Boltneva, Sofya V. Lushchekina, Irina I. Faingold, Darya A. Poletaeva, Yu. V. Soldatova, Raisa A. Kotelnikova, Igor V. Serkov et al. · 2020 · Molecules
- Lipid metabolism in Alzheimer’s diseaseZhu, Tian-Bi, Zhang, Zhao, Luo, Piao, Wang, Sha-Sha, Peng, Ye, Chu, Shi-Feng, Chen, Nai-Hong · 2019 · Brain Research Bulletin
- Metabolic perspective of astrocyte dysfunction in Alzheimer's disease and type 2 diabetes brainsZheng Shen, Zhengyang Li, Mengting Yu, Kai-Leng Tan, Si Xuan Chen · 2023 · Biomedicine & Pharmacotherapy
- The journey of boswellic acids from synthesis to pharmacological activitiesEhab A. Ragab, Mohammed F. Abdelwahab, Ahmed Soliman Doghish, Rania M. Salama, Nermin Eissa, Samar F. Darwish · 2023 · Naunyn-Schmiedeberg s Archives of Pharmacology
- Insulin/IGF Signaling-Related Gene Expression in the Brain of a Sporadic Alzheimer's Disease Monkey Model Induced by Intracerebroventricular Injection of StreptozotocinYoungjeon Lee, Young-Hyun Kim, Sang-Je Park, Jae‐Won Huh, Sang‐Hyun Kim, Sun‐Uk Kim, Jisu Kim, Kang-Jin Jeong, Kyoungmin Lee, Yonggeun Hong et al. · 2013 · Journal of Alzheimer s Disease
- Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative DisordersMartin Hofmann‐Apitius, Gordon Ball, Stephan Gebel, Shweta Bagewadi, Bernard de Bono, Reinhard Schneider, Matt Page, Alpha Tom Kodamullil, Erfan Younesi, Christian Ebeling et al. · 2015 · International Journal of Molecular Sciences
- Histone acetylation in neuronal (dys)functionEmilie M. Bonnaud, Elsa Suberbielle, Cécile E. Malnou · 2016 · BioMolecular Concepts
- Artificial neural networks in the discrimination of Alzheimer's disease using biomarkers dataAlmir Aljović, Almir Badnjević, Lejla Gurbeta · 2016 · Mediterranean Conference on Embedded Computing (MECO)
- Caspase-3-Dependent Proteolytic Cleavage of Tau Causes Neurofibrillary Tangles and Results in Cognitive Impairment During Normal AgingMeans, John C., Gerdes, Bryan C., Kaja, Simon, Sumien, Nathalie, Payne, Andrew J., Stark, Danny A., Borden, Priscilla K., Price, Jeffrey L., Koulen, Peter · 2016 · Neurochemical Research
- Pig models of neurodegenerative disorders: Utilization in cell replacement‐based preclinical safety and efficacy studiesDáša Bohačiaková, Marián Hruška-Plocháň, Carsten Reidies Bjarkam, Jens Christian Hedemann Sørensen, Miles Gregory Cunningham, David Weingarten, Joseph D. Ciacci, Štefan Juhás, Jana Juhásová, Jan Motlík et al. · 2014 · The Journal of Comparative Neurology
- Genomic Editing Tools to Model Human Diseases with Isogenic Pluripotent Stem CellsHuen Suk Kim, Jeffrey M. Bernitz, Dung‐Fang Lee, Ihor R. Lemischka · 2014 · Stem Cells and Development
- Magnetite-Amyloid-β deteriorates activity and functional organization in an in vitro model for Alzheimer’s diseaseSara Teller, Islam Bogachan Tahirbegi, Mònica Mir, Josep Samitier, Jordi Soriano · 2015 · Scientific Reports
- Icariin decreases both APP and Aβ levels and increases neurogenesis in the brain of Tg2576 miceF. Li, Hongxin Dong, Qihai Gong, Qin Wu, F. Jin, Jingshan Shi · 2015 · Neuroscience
- Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat HippocampusYue Tian, Keyan Chen, Lidan Liu, Yun-xia Dong, Ping Zhao, Shanbin Guo · 2018 · Mediators of Inflammation
- Identification of Alzheimer’s Disease Autoantibodies and Their Target Biomarkers by Phage MicroarraysPablo San Segundo‐Acosta, Ana Montero‐Calle, Manuel Fuentes, Alberto Rábano, Mayte Villalba, Rodrigo Barderas · 2019 · Journal of Proteome Research
- New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer’s Disease TreatmentMakhaeva, Galina F., Kovaleva, Nadezhda V., Boltneva, Natalia P., Lushchekina, Sofya V., Astakhova, Tatiana Yu., Rudakova, Elena V., Proshin, Alexey N., Serkov, Igor V., Radchenko, Eugene V., Palyulin, Vladimir A. et al. · 2020 · Molecules
- Apolipoprotein E: Remarkable Protein Sheds Light on Cardiovascular and Neurological DiseasesMahley, Robert W · 2017 · Clinical Chemistry
- In Vivo Chimeric Alzheimer’s Disease Modeling of Apolipoprotein E4 Toxicity in Human NeuronsNajm, Ramsey, Zalocusky, Kelly A., Zilberter, Misha, Yoon, Seo Yeon, Hao, Yanxia, Koutsodendris, Nicole, Nelson, Maxine, Rao, Antara, Taubes, Alice, Jones, Emily A. et al. · 2020 · Cell Reports