Alzheimer Mechanisms and Therapeutic Strategies

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Items 601–700 of 1,005

1. A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model
   Bin Zhang, Yuemang Yao, Anne‐Sophie Cornec, Killian Oukoloff, Michael J. James, Pyry P. Koivula, John Q. Trojanowski, Amos B. Smith, Virginia M.‐Y. Lee, Carlo Ballatore et al. · 2018 · Molecular Neurodegeneration
2. Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer’s Disease Mouse Model
   Paula Adler, Janice Mayne, Krystal Walker, Zhibin Ning, Daniel Figeys · 2019 · Journal of Proteome Research
3. Epilepsy, antiepileptic drugs and dementia
   Ettore Beghi, Massimiliano Beghi · 2020 · Current Opinion in Neurology
4. Xanthoceraside exerts anti-Alzheimer's disease effect by remodeling gut microbiota and modulating microbial-derived metabolites level in rats
   Hongxu Zhou, Jiaming Zhao, Caihong Liu, Zhengfeng Zhang, Yi Zhang, Dali Meng · 2022 · Phytomedicine
5. Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer’s disease pathology in TgSwDI and 3xTg mouse models
   Goñi, Fernando, Herline, Krystal, Peyser, Daniel, Wong, Kinlung, Ji, Yong, Sun, Yanjie, Mehta, Pankaj, Wisniewski, Thomas · 2013 · Journal of Neuroinflammation
6. Novel nicotinonitrile-coumarin hybrids as potential acetylcholinesterase inhibitors: design, synthesis, in vitro and in silico studies
   Sherif M. H. Sanad, Ahmed E. M. Mekky · 2020 · Journal of the Iranian Chemical Society
7. Valeriana amurensis improves Amyloid-beta 1-42 induced cognitive deficit by enhancing cerebral cholinergic function and protecting the brain neurons from apoptosis in mice
   Qiuhong Wang, Changfu Wang, Zunpeng Shu, Kelvin Chan, Shu-Ming Huang, Yan Li, Yang Xiao, Lihua Wu, Haixue Kuang, Xiaobo Sun · 2013 · Journal of Ethnopharmacology
8. A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins
   Priyanka Joshi, Sean Chia, Johnny Habchi, Tuomas P. J. Knowles, Christopher Martin Dobson, Michele Vendruscolo · 2016 · ACS Combinatorial Science
9. Novel multi-targeted agents for Alzheimer's disease: Synthesis, biological evaluation, and molecular modeling of novel 2-[4-(4-substitutedpiperazin-1-yl)phenyl]benzimidazoles.
   Keriman Ozadali-Sari, Tuba Tüylü Küçükkılınç, Beyza Ayazgok, A. Balkan, Oya Unsal-Tan · 2017 · Bioorganic chemistry (Print)
10. Comparative Study of Different Polar Groups of EPA‐Enriched Phospholipids on Ameliorating Memory Loss and Cognitive Deficiency in Aged SAMP8 Mice
    Miaomiao Zhou, Hongxia Che, Jiaqi Huang, Tian‐tian Zhang, Jie Xu, Changhu Xue, Yuming Wang · 2018 · Molecular Nutrition & Food Research
11. ApoE-associated modulation of neuroprotection from Aβ-mediated neurodegeneration in transgenic Caenorhabditis elegans
    Edward F. Griffin, Samuel E. Scopel, Cayman A. Stephen, Adam C. Holzhauer, Madeline A Vaji, Ryan A. Tuckey, Laura A. Berkowitz, Kim A. Caldwell, Guy A. Caldwell · 2019 · Disease Models & Mechanisms
12. Inhibiting Aβ toxicity in Alzheimer's disease by a pyridine amine derivative
    Zhenzhu Zhu, Tao Yang, Lei Zhang, Lulu Liu, Enmao Yin, Changli Zhang, Zijian Guo, Xu Chen, Xiaoyong Wang · 2019 · European Journal of Medicinal Chemistry
13. Therapeutic Effects of Natural Drugs on Alzheimer’s Disease
    Yuan Ma, Manwen Yang, Xinwei Li, Jian-wei Yue, Junzong Chen, Mei-wen Yang, Xuan Huang, Lianlian Zhu, Fen‐Fang Hong, Shu‐Long Yang · 2019 · Frontiers in Pharmacology
14. Phosphodiesterase 5 inhibitors as novel agents for the treatment of Alzheimer’s disease
    Li Liu, Huang Xu, Shumin Ding, Dongyan Wang, Guoqiang Song, Xianfeng Huang · 2019 · Brain Research Bulletin
15. Neuronal ApoE4 in Alzheimer’s disease and potential therapeutic targets
    Zhang, Lan, Xia, Yiyuan, Gui, Yuran · 2023 · Frontiers in Aging Neuroscience
16. Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer’s Disease Cell Model
    Huiyu Liang, Yusheng Shi, Zhewen Kou, Yonghua Peng, Wenjun Chen, Xiaowen Li, Shuji Li, Ying Wang, Fang Wang, Xingmei Zhang · 2015 · PLoS ONE
17. MEF2C mRNA expression and cognitive function in Japanese patients with Alzheimer's disease
    Tomoko Sao, Yuta Yoshino, Kiyohiro Yamazaki, Yuki Ozaki, Yoko Mori, Shinichiro Ochi, Taku Yoshida, Takaaki Mori, Jun‐ichi Iga, Shuichi Ueno · 2017 · Psychiatry and Clinical Neurosciences
18. Novel chelators based on adamantane-derived semicarbazones and hydrazones that target multiple hallmarks of Alzheimer's disease
    Duraippandi Palanimuthu, Zhixuan Wu, Patric J. Jansson, Nady Braidy, Paul V. Bernhardt, Des Raymond Richardson, Danuta S. Kalinowski · 2018 · Dalton Transactions
19. Comparison of the effects of selenomethionine and selenium-enriched yeast in the triple-transgenic mouse model of Alzheimer's disease
    Zhong-Hao Zhang, Qiuyan Wu, Chen Chen, Rui Zheng, Yao Chen, Jiazuan Ni, Guo-Li Song · 2018 · Food & Function
20. N-terminal tau truncation in the pathogenesis of Alzheimer's disease (AD): Developing a novel diagnostic and therapeutic approach
    Giuseppina Amadoro, Valentina Latina, Veronica Corsetti, Pietro Calissano · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
21. Potassium channels in the neuronal homeostasis and neurodegenerative pathways underlying Alzheimer’s disease: An update
    Chiara Villa, Huriye Suphesiz, Romina Combi, Enes Akyüz · 2019 · Mechanisms of Ageing and Development
22. The Role of Epigallocatechin-3-Gallate in Autophagy and Endoplasmic Reticulum Stress (ERS)-Induced Apoptosis of Human Diseases
    Shuangshuang Zhang, Mengke Cao, Fang Fang · 2020 · Medical Science Monitor
23. Composite of gold nanoclusters and basified human serum albumin significantly boosts the inhibition of Alzheimer's β-amyloid by photo-oxygenation
    Wei Liu, Hui Zhang, Xiaoyan Dong, Yan Ping Sun · 2022 · Acta Biomaterialia
24. The potential of solanezumab and gantenerumab to prevent Alzheimer’s disease in people with inherited mutations that cause its early onset
    Panza, Francesco, Seripa, Davide, Lozupone, Madia, Solfrizzi, Vincenzo, Imbimbo, Bruno P., Barulli, Maria Rosaria, Tortelli, Rosanna, Capozzo, Rosa, Bisceglia, Paola, Dimitri, Andrea et al. · 2018 · Expert Opinion on Biological Therapy
25. Stimuli-controllable iron oxide nanoparticle assemblies: Design, manipulation and bio-applications
    Liang Ee Low, Hui Peng Lim, Yong Sze Ong, Sangeetaprivya P. Siva, Chin Siew Sia, Bey Hing Goh, Eng‐Seng Chan, Beng Ti Tey · 2022 · Journal of Controlled Release
26. Caenorhabditis elegans: A transgenic model for studying age-associated neurodegenerative diseases
    Nisha Rani, Mohammad Mumtaz Alam, Azfar Jamal, Usama Bin Ghaffar, Suhel Parvez · 2023 · Ageing Research Reviews
27. Multiscale proteomic modeling reveals protein networks driving Alzheimer’s disease pathogenesis
    Erming Wang, Kaiwen Yu, Jiqing Cao, Minghui Wang, Pavel Katsel, Won‐Min Song, Zhen Wang, Yuxin Li, Xusheng Wang, Qian Wang et al. · 2025 · Cell
28. The Flavonoid Derivative 2-(4′ Benzyloxyphenyl)-3-hydroxy-chromen-4-one Protects Against Aβ42-Induced Neurodegeneration in Transgenic Drosophila: Insights from In Silico and In Vivo Studies
    Sandeep Kumar Singh, Ruchi Gaur, Akhil Kumar, Roshan Fatima, Lallan Mishra, Saripella Srikrishna · 2014 · Neurotoxicity Research
29. The synergistic effect between KLVFF and self-assembly chaperones on both disaggregation of beta-amyloid fibrils and reducing consequent toxicity
    Aoting Qu, Fan Huang, Ang Li, Huiru Yang, Hao Zhou, Jiafu Long, Linqi Shi · 2016 · Chemical Communications
30. LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1ΔE9 transgenic mice
    Jianhui Wang, Xi Lei, Xiaorui Cheng, Xiaorui Zhang, Gang Liu, Junping Cheng, Yiran Xu, Zeng Ju, Wenxia Zhou, Yongxiang Zhang · 2016 · Alzheimer s Research & Therapy
31. INPP5D mRNA Expression and Cognitive Decline in Japanese Alzheimer’s Disease Subjects
    Yoshino, Yuta, Yamazaki, Kiyohiro, Ozaki, Yuki, Sao, Tomoko, Yoshida, Taku, Mori, Takaaki, Mori, Yoko, Ochi, Shinichiro, Iga, Jun-Ichi, Ueno, Shu-Ichi · 2017 · Journal of Alzheimer's Disease
32. GelRed/[G3T]5/Tb3+ hybrid: A novel label-free ratiometric fluorescent probe for H2O2 and oxidase-based visual biosensing
    Jieqiong Chen, Shi-Fan Xue, Zi‐Han Chen, Shengqiang Zhang, Guoyue Shi, Min Zhang · 2017 · Biosensors and Bioelectronics
33. Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
    Xiaodan Guo, Jianlu Lv, Jian Lu, Lei Fan, Xi Huang, Lihong Hu, Jiaying Wang, Xu Shen · 2017 · Neuropharmacology
34. Neuronal levels and sequence of tau modulate the power of brain rhythms
    Melanie M. Das, Sumihiro Maeda, Bozhong Hu, Gui-Qiu Yu, Weikun Guo, Isabel Lopez, Xinxing Yu, Chao Tai, Xin Wang, Lennart Mucke · 2018 · Neurobiology of Disease
35. The Novel DA–CH3 Dual Incretin Restores Endoplasmic Reticulum Stress and Autophagy Impairments to Attenuate Alzheimer-Like Pathology and Cognitive Decrements in the APP SWE /PS1 ΔE9 Mouse Model
    Theodora Panagaki, Simon Gengler, Christian Hölscher · 2018 · Journal of Alzheimer s Disease
36. Recent advances in stem cells therapy: A focus on cancer, Parkinson’s and Alzheimer’s
    Dalia Fleifel, Mai Atef Rahmoon, Abdelrahman AlOkda, Mostafa Nasr, Menattallah Elserafy, Sherif F. El‐Khamisy · 2018 · Journal of Genetic Engineering and Biotechnology
37. X-ray fluorescence imaging of metals and metalloids in biological systems.
    Run Zhang, Li Li, Yasmina F. Sultanbawa, Zhi Ping Xu · 2018 · Europe PMC (PubMed Central)
38. Design, synthesis and evaluation of novel ferulic acid derivatives as multi-target-directed ligands for the treatment of Alzheimer’s disease
    Jinshuai Lan, Ruifeng Zeng, Xiaoyi Jiang, Jianwei Hou, Yun Liu, Zheng-Hao Hu, Hongxin Li, Yin Li, Sai‐Sai Xie, Yue Ding et al. · 2019 · Bioorganic Chemistry
39. Integrated network pharmacology and zebrafish model to investigate dual-effects components of Cistanche tubulosa for treating both Osteoporosis and Alzheimer's Disease.
    Yingqi Li, Yi Chen, Jia-Yi Fang, Si-Qi Jiang, Ping Li, Fei Li · 2020 · Journal of Ethnopharmacology
40. Engineering a pathological tau-targeted nanochaperone for selective and synergetic inhibition of tau pathology in Alzheimer's Disease
    Linlin Xu, Yuxun Ding, Feihe Ma, Yue Chen, Guidong Chen, Lin Zhu, Jiafu Long, Rujiang Ma, Yang Liu, Jianfeng Liu et al. · 2022 · Nano Today
41. Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer
    Amoah, Solomon K.S., Dalla Vecchia, Maria Tereza, Pedrini, Beatriz, Carnhelutti, Gabriela Lazzarotto, Gonçalves, Ana Elisa, dos Santos, Diogo Adolfo, Biavatti, Maique W., de Souza, Márcia Maria · 2015 · European Journal of Pharmacology
42. Therapeutic approaches for improving cognitive function in the aging brain
    Lingmin Chen, Jiao Jiao, Yonggang Zhang · 2022 · Frontiers in Neuroscience
43. Apolipoprotein E4 targets mitochondria and the mitochondria-associated membrane complex in neuropathology, including Alzheimer's disease
    Mahley, Robert W. · 2023 · Current Opinion in Neurobiology
44. Circular RNAs in neurological conditions – computational identification, functional validation, and potential clinical applications
    Oak Hatzimanolis, Alex M. Sykes, Alexandre S. Cristino · 2025 · Molecular Psychiatry
45. Peripheral Amyloid Levels Present Gender Differences Associated with Aging in AβPP/PS1 Mice
    Lara Ordóñez‐Gutiérrez, Marta Antón, Francisco G. Wandosell · 2015 · Journal of Alzheimer s Disease
46. Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity
    Cinzia Severini, Roberta Lattanzi, Daniela Maftei, Veronica Marconi, Maria Teresa Ciotti, Pamela Petrocchi Passeri, Fulvio Florenzano, Ester DEL DUCA, Silvia Caioli, Cristina Zona et al. · 2015 · Scientific Reports
47. A Lipoprotein Receptor Cluster IV Mutant Preferentially Binds Amyloid-β and Regulates Its Clearance from the Mouse Brain
    Abhay P. Sagare, Robert D. Bell, Alaka Srivastava, Jesse D. Sengillo, Itender Singh, Yoichiro Nishida, Nienwen Chow, Berislav V. Zloković · 2013 · Journal of Biological Chemistry
48. Hydroxy-safflor yellow A inhibits neuroinflammation mediated by Aβ1–42 in BV-2 cells
    Zuohui Zhang, Zhengzheng Wu, Xiaolei Zhu, Xin-chen Hui, Jie Pan, Yun Xu · 2014 · Neuroscience Letters
49. Computational design of novel flavonoid analogues as potential AChE inhibitors: analysis using group-based QSAR, molecular docking and molecular dynamics simulations
    Chakshu Vats, Jaspreet Kaur Dhanjal, Sukriti Goyal, Navneeta Bharadvaja, Abhinav Grover · 2014 · Structural Chemistry
50. 1,4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood–brain barrier
    Michaela Prinz, Sülünay Parlar, Gülşah Bayraktar, Vildan Alptüzün, Erçin Erciyas, Adyary Fallarero, Daniela Karlsson, Pia Maarit Vuorela, Małgorzata Burek, Carola Yvette Förster et al. · 2013 · European Journal of Pharmaceutical Sciences
51. Cellular Source-Specific Effects of Apolipoprotein (Apo) E4 on Dendrite Arborization and Dendritic Spine Development
    Sachi Jain, Seo Yeon Yoon, Laura Leung, Johanna Knöferle, Yadong Huang · 2013 · PLoS ONE
52. Antibody modified-silver nanoparticles for colorimetric immuno sensing of Aβ(1–40/1–42) based on the interaction between β-amyloid and Cu2+
    Tao Hu, Chuanxia Chen, Guangming Huang, Xiurong Yang · 2016 · Sensors and Actuators B Chemical
53. β-Amyloid Amorphous Aggregates Induced by the Small Natural Molecule Ferulic Acid
    Emilia Bramanti, Lorenzo Fulgentini, Ranieri Bizzarri, Francesco Lenci, Antonella Sgarbossa · 2013 · The Journal of Physical Chemistry B
54. Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis
    Tayyaba Qureshi, Mona Bjørkmo, Kaja Nordengen, Vidar Gundersen, Tor Paaske Utheim, Leiv Otto Watne, Jon Storm‐Mathisen, Bjørnar Hassel, Farrukh Abbas Chaudhry · 2020 · Cells
55. Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease
    Галина Ф. Махаева, Надежда Владимировна Ковалева, Елена Владимировна Рудакова, Natalia P. Boltneva, Maria V. Grishchenko, Sofya V. Lushchekina, T. Yu. Astakhova, Olga G. Serebryakova, Elena N. Timokhina, Ekaterina F. Zhilina et al. · 2023 · International Journal of Molecular Sciences
56. Multi-functional role of apolipoprotein E in neurodegenerative diseases
    Sadequl Islam, A. Noorani, Yang Sun, Makoto Michikawa, Kun Zou · 2025 · Frontiers in Aging Neuroscience
57. Involvement of 5-Lipoxygenase in Alzheimer's Disease: A Role for DNA Methylation
    Andrea Di Francesco, Beatrice Arosio, Cristina Gussago, Enrico Dainese, Daniela Mari, Claudio D’Addario, Mauro Maccarrone · 2013 · Journal of Alzheimer s Disease
58. Amyloid-beta neuroprotection mediated by a targeted antioxidant
    Courtney R. Giordano, Laura J. Terlecky, Aliccia B. Bollig-Fischer, Paul A. Walton, Stanley R. Terlecky · 2014 · Scientific Reports
59. Current advances in systems and integrative biology
    Scott William Robinson, Marco Fernandes, Holger Husi · 2014 · Computational and Structural Biotechnology Journal
60. Lignans from Schisandra chinensis ameliorate cognition deficits and attenuate brain oxidative damage induced by D-galactose in rats
    Tingxu Yan, Lei Shang, Mengshi Wang, Chenning Zhang, Xu Dong Zhao, BI Kai-shun, Ying Jia · 2016 · Metabolic Brain Disease
61. Co-encapsulation ofNigella sativaoil and plasmid DNA for enhanced gene therapy of Alzheimer’s disease
    Abd Almonem Doolaanea, Nur Izzati Mansor, Nurul Hafizah Mohd Nor, Farahidah Mohamed · 2016 · Journal of Microencapsulation
62. Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation
    Gao‐Feng Zha, Cheng‐Pan Zhang, Hua‐Li Qin, Ibrahim Jantan, Muhammad Sher, Muhammad Wahab Amjad, Muhammad Ajaz Hussain, Zahid Hussain, Syed Nasir Abbas Bukhari · 2016 · Bioorganic & Medicinal Chemistry
63. Deep Brain Magnetic Stimulation Promotes Neurogenesis and Restores Cholinergic Activity in a Transgenic Mouse Model of Alzheimer’s Disease
    Junli Zhen, Yanjing Qian, Jian Fu, Ruijun Su, Haiting An, Wei Wang, Yan Zheng, Xiaomin Wang · 2017 · Frontiers in Neural Circuits
64. Neuroprotective effect of paeoniflorin on okadaic acid-induced tau hyperphosphorylation via calpain/Akt/GSK-3β pathway in SH-SY5Y cells
    Xiaohui Ma, Wen‐Jun Duan, Yousheng Mo, Junli Chen, Li Shi, Wei Zhao, Lei Yang, Suiqing Mi, Xinliang Mao, Hong Wang et al. · 2018 · Brain Research
65. CA-30, an oligosaccharide fraction derived from Liuwei Dihuang decoction, ameliorates cognitive deterioration via the intestinal microbiome in the senescence-accelerated mouse prone 8 strain
    Jianhui Wang, Xi Lei, Zongjie Xie, Xiaorui Zhang, Xiaorui Cheng, Wenxia Zhou, Yongxiang Zhang · 2019 · Aging
66. Insulin-Mediated Changes in Tau Hyperphosphorylation and Autophagy in a Drosophila Model of Tauopathy and Neuroblastoma Cells
    Shreyasi Chatterjee, Surendra S. Ambegaokar, George R. Jackson, Amritpal K. Mudher · 2019 · Frontiers in Neuroscience
67. MiR-335-5p Inhibits β-Amyloid (Aβ) Accumulation to Attenuate Cognitive Deficits Through Targeting c-jun-N-terminal Kinase 3 in Alzheimer’s Disease
    Dan Wang, Zhifu Fei, Song Luo, Hai Wang · 2020 · Current Neurovascular Research
68. Cyanidin-3- O -glucoside inhibits Aβ40 fibrillogenesis, disintegrates preformed fibrils, and reduces amyloid cytotoxicity
    Fufeng Liu, Fang Zhao, Wenjuan Wang, Jingcheng Sang, Longgang Jia, Li Li, Fuping Lu · 2020 · Food & Function
69. Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases
    Xixi Zhang, Deming Zhao, Wei Wu, Syed Zahid Ali Shah, Mengyu Lai, Dongming Yang, Jie Li, Zhiling Guan, Wen Li, Hong‐Li Gao et al. · 2020 · Aging
70. Suppression of a core metabolic enzyme dihydrolipoamide dehydrogenase (dld) protects against amyloid beta toxicity in C. elegans model of Alzheimer's disease
    Waqar Ahmad, P. Ebert · 2020 · Genes and Diseases
71. Potent Tau Aggregation Inhibitor D‐Peptides Selected against Tau‐Repeat 2 Using Mirror Image Phage Display
    Marwa Malhis, Senthilvelrajan Kaniyappan, Isabelle Aillaud, RamReddy Chandupatla, Lisa Marie Ramirez, Markus Zweckstetter, Anselm H. C. Horn, Eckhard Mandelkow�, Heinrich Sticht, Susanne Aileen Funke · 2021 · ChemBioChem
72. Kir Channel Molecular Physiology, Pharmacology, and Therapeutic Implications
    Meng Cui, Lucas Cantwell, Andrew Zorn, Diomedes E. Logothetis · 2021 · Handbook of experimental pharmacology
73. Challenges in LC–MS-based metabolomics for Alzheimer’s disease early detection: targeted approaches versus untargeted approaches
    Pierluigi Reveglia, Carmela Paolillo, Gabriella Ferretti, Armando De Carlo, Antonella Angiolillo, Rosarita Nasso, Mafalda Caputo, Carmela Matrone, Alfonso Di Costanzo, Gaetano Corso · 2021 · Metabolomics
74. Neuroactive compounds obtained from arthropod venoms as new therapeutic platforms for the treatment of neurological disorders
    Victoria Monge‐Fuentes, Flávia Maria Medeiros Gomes, Gabriel Avohay Alves Campos, Juliana de Castro Silva, Andréia Mayer Biolchi, Lilian Carneiro dos Anjos, Jacqueline Coimbra Gonçalves, Kamila Soares Lopes, Márcia Renata Mortari · 2015 · The Journal of venomous animals and toxins including tropical diseases
75. Brain-neuron targeted nanoparticles for peptide synergy therapy at dual-target of Alzheimer’s disease
    Guo, Qian, Li, Yixian, Xu, Shuting, Wang, Pengzhen, Qian, Kang, Yang, Peng, Sheng, Dongyu, Wang, Liuchang, Cheng, Yunlong, Meng, Ran et al. · 2023 · Journal of Controlled Release
76. Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer’s disease model
    Antara T. Rao, Nuo Chen, Min Joo Kim, Jessica R. Blumenfeld, Oscar Yip, Zherui Liang, David M. Shostak, Yanxia Hao, Maxine R. Nelson, Nicole Koutsodendris et al. · 2024 · Cell stem cell
77. Dynamin‐2 in nervous system disorders
    Arlek M. González‐Jamett, Valentina Haro‐Acuña, Fanny Momboisse, Pablo A. Caviedes, Jorge Alfredo Bevilacqua, Ana M. Cárdenas · 2013 · Journal of Neurochemistry
78. β-Secretase BACE1 Regulates Hippocampal and Reconstituted M-Currents in a β-Subunit-Like Fashion
    Sabine Hessler, Fang Zheng, Stephanie Hartmann, Andrea Rittger, Sandra Lehnert, Meike Völkel, Matthias Nissen, Elke Edelmann, Paul Säftig, Michael Schwake et al. · 2015 · Journal of Neuroscience
79. Introduction into PPPM as a new paradigm of public health service: an integrative view
    T. A. Bodrova, Dmitry S. Kostyushev, Elena Antonova, Shimon Slavin, Dmitry Gnatenko, Mariia Bocharova, Michael Legg, Paolo Pozzilli, Mikhail A. Paltsev, Sergey V. Suchkov · 2012 · The EPMA Journal
80. Imaging Multimodalities for Dissecting Alzheimer's Disease: Advanced Technologies of Positron Emission Tomography and Fluorescence Imaging
    Masafumi Shimojo, Makoto Higuchi, Tetsuya Suhara, Naruhiko Sahara · 2015 · Frontiers in Neuroscience
81. Use ofade1andade2mutations for development of a versatile red/white colour assay of amyloid-induced oxidative stress insaccharomyces cerevisiae
    Vidhya Bharathi, Amandeep Girdhar, Archana Prasad, Verma Meenkshi, Vibha Taneja, Basant Kumar Patel · 2016 · Yeast
82. Tau Pathology Promotes the Reorganization of the Extracellular Matrix and Inhibits the Formation of Perineuronal Nets by Regulating the Expression and the Distribution of Hyaluronic Acid Synthases
    Yin Li, Zexu Li, Tan Jin, Zhan‐You Wang, Pu Zhao · 2017 · Journal of Alzheimer s Disease
83. Neuroprotective effects of berberine on recognition memory impairment, oxidative stress, and damage to the purinergic system in rats submitted to intracerebroventricular injection of streptozotocin
    Juliana Sorraila de Oliveira, Fátima Husein Abdalla, Guilherme Lopes Dornelles, Taís Vidal Palma, Cristiane Signor, Jamile Bernardi, Jucimara Baldissarelli, Luana Suéling Lenz, Vitor Antunes de Oliveira, Maria Rosa Chitolina Schetinger et al. · 2018 · Psychopharmacology
84. Purinergic signaling in Alzheimer’s disease
    Laurie Erb, Lucas T. Woods, Mahmoud G. Khalafalla, Gary A. Weisman · 2018 · Brain Research Bulletin
85. Chromenones as Multineurotargeting Inhibitors of Human Enzymes
    Carina Lemke, Joscha Christmann, Jiafei Yin, Jose Miguel Alonso, Estefanía Serrano, Mourad Chioua, Lhassane Ismaïli, A. MARTINEZ‐GRAU, Christopher D. Beadle, Tatiana N. Vetman et al. · 2019 · ACS Omega
86. Density of GABAB Receptors Is Reduced in Granule Cells of the Hippocampus in a Mouse Model of Alzheimer’s Disease
    Alejandro Martín‐Belmonte, Carolina Aguado, Rocío Alfaro‐Ruiz, Ana Esther Moreno‐Martínez, Luis de la Ossa, José Martínez Hernández, Alain Buisson, Ryuichi Shigemoto, Yugo Fukazawa, Rafael Luján · 2020 · International Journal of Molecular Sciences
87. Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation
    Jing Xu, Tao Yu, Enrica Caterina Pietronigro, Jia Yuan, Jessica Arioli, Yifei Pei, Xuan Luo, Jialin Ye, Gabriela Constantin, Chaoming Mao et al. · 2020 · PLoS Biology
88. New thiazole and thiazole-chromene hybrids possessing morpholine units: Piperazine-mediated one-pot synthesis of potential acetylcholinesterase inhibitors
    Ahmed E. M. Mekky, Sherif M. H. Sanad, Tamer T. El‐Idreesy · 2021 · Synthetic Communications
89. PAK Inactivation Impairs Social Recognition in 3xTg-AD Mice without Increasing Brain Deposition of Tau and A
    Dany Arsenault, Alexandre Dal‐Pan, Cyntia Tremblay, David Alan Bennett, Matthieu J. Guitton, Yves De Koninck, Susumu Tonegawa, Frédéric Calon · 2013 · Journal of Neuroscience
90. Chemical modulation of Kv7 potassium channels
    Borgini, Matteo, Mondal, Pravat, Liu, Ruiting, Wipf, Peter · 2021 · RSC Medicinal Chemistry
91. Efficacy of cyclin dependent kinase 4 inhibitors as potent neuroprotective agents against insults relevant to alzheimer's disease
    Sanphui, Priyankar, Pramanik, Sumit Kumar, Chatterjee, Nandini, Moorthi, Ponnusamy, Banerji, Biswadip, Biswas, Subhas Chandra · 2013 · PLoS ONE
92. Sevoflurane anaesthesia induces cognitive impairment in young mice through sequential tau phosphorylation
    Feng Liang, Mengzhu Li, Miao Xu, Yiying Zhang, Yuanlin Dong, Sulpicio G. Soriano, Mary Ellen McCann, Guang Yang, Zhongcong Xie · 2023 · British Journal of Anaesthesia
93. Quantitative Amyloid Imaging Using Image-Derived Arterial Input Function
    Yi Su, Tyler Blazey, Abraham Z. Snyder, Marcus E. Raichle, Russ C. Hornbeck, Patricia Aldea, John C. Morris, Tammie L.S. Benzinger · 2015 · PLoS ONE
94. Voluntary exercise counteracts Aβ25-35-induced memory impairment in mice
    Qin Lin Wang, Zhiqiang Xu, Jinrong Tang, Jianguo Sun, Junying Gao, Ting Wu, Ming Xiao · 2013 · Behavioural Brain Research
95. Aβ-Immunotherapeutic strategies: a wide range of approaches for Alzheimer's disease treatment
    Laia Montoliu‐Gaya, Sandra Villegas · 2016 · Expert Reviews in Molecular Medicine
96. Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer’s disease
    Xin Lü, Si-yu He, Qi Li, Hongyu Yang, Xueyang Jiang, Hongzhi Lin, Yao Chen, Wei Qu, Feng Feng, Yaoyao Bian et al. · 2018 · Bioorganic & Medicinal Chemistry
97. d -Enantiomeric RTHLVFFARK-NH2: A Potent Multifunctional Decapeptide Inhibiting Cu2+-Mediated Amyloid β-Protein Aggregation and Remodeling Cu2+-Mediated Amyloid β Aggregates
    Wei Liu, Xiaoyan Dong, Yan Ping Sun · 2019 · ACS Chemical Neuroscience
98. Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease
    Al-Atrache, Zein, Lopez, Danielle B., Hingley, Susan T., Appelt, Denah M. · 2019 · BMC Neuroscience
99. Alpha-asarone improves cognitive function of aged rats by alleviating neuronal excitotoxicity via GABAA receptors
    Yu Chen, Xiaofeng Gao, Qi Liu, Lili Zeng, Kun Zhang, Keman Mu, Di Zhang, Huixi Zou, Nan Wu, Jierui Ou et al. · 2019 · Neuropharmacology
100. Oral glutathione administration inhibits the oxidative stress and the inflammatory responses in AppNL−G-F/NL−G-F knock-in mice
     Hisanao Izumi, Keita Sato, Kazuhiro Kojima, Takashi Saito, Takaomi C. Saido, Kohji Fukunaga · 2020 · Neuropharmacology