Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

Bar-Peled, Liron, Schweitzer, Lawrence D., Zoncu, Roberto, Sabatini, David M.·2012·Cell

Cited by (914)

Items 401–500 of 914

  1. Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin
    Marjorie A. Carnero Corrales, Sarah Zinken, Georgios Konstantinidis, Muhammad Rafehi, Aliaa Abdelrahman, Yao‐Wen Wu, Petra Janning, Christa Elisabeth Müller, Luca Laraia, Herbert Waldmann · 2021 · Cell chemical biology
  2. The regulation of healthspan and lifespan by dietary amino acids
    Reji Babygirija, Dudley W. Lamming · 2021 · Translational Medicine of Aging
  3. Autophagy and Cell Death to Target Cancer Cells: Exploiting Synthetic Lethality as Cancer Therapies
    Julie Reyjal, Kévin Cormier, Sandra Turcotte · 2013 · Advances in experimental medicine and biology
  4. Metformin: An Inhibitor of mTORC1 Signaling
    Bodo Clemens Melnik, Gerd Schmitz · 2014
  5. Exploiting cancer vulnerabilities: mTOR, autophagy, and homeostatic imbalance
    Charlotte E. Johnson, Andrew R. Tee · 2017 · Essays in Biochemistry
  6. Sensors for the mTORC1 pathway regulated by amino acids
    Xiu-zhi Li, Xianghua Yan · 2019 · Journal of Zhejiang University SCIENCE B
  7. Nutrient Signaling and Lysosome Positioning Crosstalk Through a Multifunctional Protein, Folliculin
    Natàlia de Martín Garrido, C.H.S. Aylett · 2020 · Frontiers in Cell and Developmental Biology
  8. Therapeutic mTOR blockade in systemic autoimmunity: Implications for antiviral immunity and extension of lifespan
    Christian Geier, András Perl · 2021 · Autoimmunity Reviews
  9. Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling
    Xia, Jing, Wang, Rong, Zhang, Tianlong, Ding, Jianping · 2016 · Cell Discovery
  10. Sepsis-induced changes in amino acid transporters and leucine signaling via mTOR in skeletal muscle
    Lacee Jay Laufenberg, Anne M. Pruznak, Maithili Navaratnarajah, Charles H. Lang · 2014 · Amino Acids
  11. SnapShot: mTORC1 Signaling at the Lysosomal Surface
    Liron Bar‐Peled, David M. Sabatini · 2012 · Cell
  12. Sensing the Environment Through Sestrins: Implications for Cellular Metabolism
    Anita Parmigiani, Andrei V. Budanov · 2016 · International review of cytology
  13. Caloric restriction maintains stem cells through niche and regulates stem cell aging
    Nagarajan Maharajan, Karthikeyan A. Vijayakumar, Chul Ho Jang, Goang‐Won Cho · 2019 · Journal of Molecular Medicine
  14. Nutrient Control of mRNA Translation
    Xin Erica Shu, Robert V. Swanda, Shu‐Bing Qian · 2020 · Annual Review of Nutrition
  15. Amino Acids in Cell Signaling: Regulation and Function.
    Sudikshya Paudel, Guo-Yao Wu, Xiao-Qiu Wang · 2021 · Advances in Experimental Medicine and Biology
  16. Molecular Mechanisms Underlying Initiation and Activation of Autophagy
    Z J Wei, Xiao Hu, Yumeng Wu, Liming Zhou, Manhan Zhao, Qiong Lin · 2024 · Biomolecules
  17. Therapeutic Targeting of Cellular Metabolism in Cells with Hyperactive mTORC1: A Paradigm Shift
    Doug A. Medvetz, Carmen Priolo, Elizabeth P. Henske · 2014 · Molecular Cancer Research
  18. Prolyl hydroxylase domain enzymes and their role in cell signaling and cancer metabolism
    Tra-Ly Nguyen, Raúl V. Durán · 2016 · The International Journal of Biochemistry & Cell Biology
  19. Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epithelium
    Bo Yu, Anuoluwapo Egbejimi, Rachayata Dharmat, Pei Xu, Zhenyang Zhao, Bo Long, Hongyu Miao, Rui Chen, Theodore G. Wensel, Jiyang Cai et al. · 2018 · Science Signaling
  20. The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas
    Anika Bongaarts, Jackelien van Scheppingen, Anatoly Korotkov, Caroline Mijnsbergen, Jasper J. Anink, Floor E. Jansen, Wim G.M. Spliet, Wilfred F.A. den Dunnen, Victoria‐Elisabeth Gruber, Theresa O. Scholl et al. · 2019 · Brain
  21. Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1
    Erik L. Brincks, James Adams, Lifu Wang, Benjamin A. Turner, Agnieszka Marcinowicz, Jiyuan Ke, Michael Essmann, Lucía M. Mautino, Clarissa Van Allen, Sanjeev Kumar et al. · 2020 · Oncotarget
  22. The Roles of Post-Translational Modifications on mTOR Signaling
    Shasha Yin, Liu Liu, Wenjian Gan · 2021 · International Journal of Molecular Sciences
  23. RETRACTED ARTICLE: Optimization of oncolytic effect of Newcastle disease virus Clone30 by selecting sensitive tumor host and constructing more oncolytic viruses
    Tianyan Liu, Yu Zhang, Yukai Cao, Shan Jiang, Rui Sun, Jiechao Yin, Zhenqiu Gao, Guiping Ren, Zhenzhong Wang, Qingzhong Yu et al. · 2020 · Gene Therapy · Retracted
  24. The origin of prostate metastases: emerging insights
    M. Santoni, F. Piva, M. Scarpelli, Liang Cheng, A. López-Beltran, F. Massari, R. Iacovelli, R. Berardi, D. Santini, R. Montironi · 2015 · Cancer Metastasis Review
  25. The oncoprotein hepatitis B X-interacting protein promotes the migration of ovarian cancer cells through the upregulation of S-phase kinase-associated protein 2 by Sp1
    Fu-qiang Xu, Xiaoming Zhu, Tao Han, Xiaona You, Fabao Liu, Lihong Ye, Xiaodong Zhang, Xiaohong Wang, Yuanqing Yao · 2014 · International Journal of Oncology
  26. RES-529
    Mark A. Weinberg · 2016 · Anti-Cancer Drugs
  27. p18/LAMTOR1
    Shigeyuki Nada, Shunsuke Mori, Yusuke Takahashi, Masato Okada · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
  28. Mild Fixation and Permeabilization Protocol for Preserving Structures of Endosomes, Focal Adhesions, and Actin Filaments During Immunofluorescence Analysis
    Julia M. Scheffler, Natalia Schiefermeier-Mach, Lukas Alfons Huber · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
  29. Loss of hepatic DEPTOR alters the metabolic transition to fasting
    Alexandre Caron, Mathilde Mouchiroud, Nicolas Gautier, Sébastien M. Labbé, Romain Villot, Laurie Turcotte, Blandine Secco, Guillaume Lamoureux, Michaël Shum, Yves Gélinas et al. · 2017 · Molecular Metabolism
  30. Amino acid and small GTPase regulation of mTORC1
    Thu P. Nguyen, Anderson R. Frank, Jenna L. Jewell · 2017 · Cellular Logistics
  31. The V-ATPase a3 Subunit: Structure, Function and Therapeutic Potential of an Essential Biomolecule in Osteoclastic Bone Resorption
    Anh Chu, Ralph A. Zirngibl, Morris Frank Manolson · 2021 · International Journal of Molecular Sciences
  32. LAMTOR1 inhibition of TRPML1‐dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function
    Jiandong Sun, Yan Liu, Xiaoning Hao, Wei Lin, Wenyue Su, Emerald Chiang, Michel Baudry, Xiaoning Bi · 2022 · The EMBO Journal
  33. Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle
    Ted G. Graber, Michael S. Borack, Paul T. Reidy, Elena Volpi, Blake B. Rasmussen · 2017 · Nutrition & Metabolism
  34. RagC phosphorylation autoregulates mTOR complex 1
    Guang Yang, Sean J. Humphrey, Danielle S. Murashige, D. Francis, Qiao-Ping Wang, Kristen C. Cooke, G. Neely, David E. James · 2018 · EMBO Journal
  35. Noncanonical Inhibition of mTORC1 by Coxiella burnetii Promotes Replication within a Phagolysosome-Like Vacuole
    Charles L. Larson, Kelsi M. Sandoz, Diane C. Cockrell, Robert A. Heinzen · 2019 · mBio
  36. Signal Transduction: From the Atomic Age to the Post-Genomic Era
    Jeremy W. Thorner, Tony Hunter, Lewis C. Cantley, Richard Sever · 2014 · Cold Spring Harbor Perspectives in Biology
  37. Ring domains are essential for GATOR2-dependent mTORC1 activation
    Cong Jiang, Xiaoming Dai, Shao-Hui He, Hongfei Zhou, Lan Fang, Jian-ping Guo, Song-Lei Liu, Tao Zhang, W. Pan, Hai-Hong Yu et al. · 2022 · Molecules and Cells
  38. Nutrient sensing of mTORC1 signaling in cancer and aging
    Cong Jiang, Xiao Tan, Ning Liu, Peiqiang Yan, Tao Hou, Wenyi Wei · 2024 · Seminars in Cancer Biology
  39. Rag–Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway
    Max L. Valenstein, Pranav V. Lalgudi, Xin Gu, Jibril F. Kedir, Martin S. Taylor, R. Chivukula, David M. Sabatini · 2024 · Proceedings of the National Academy of Sciences of the United States of America
  40. Disruption of the Rag-Ragulator complex by c17orf59 inhibits mTORC1
    Lawrence D. Schweitzer, William C. Comb, L. Bar-Peled, D. Sabatini · 2015 · Cell Reports
  41. Stability of the Endosomal Scaffold Protein LAMTOR3 Depends on Heterodimer Assembly and Proteasomal Degradation
    Mariana E. G. de Araújo, Taras Stasyk, Nicole Taub, Hannes L. Ebner, Beatrix Fürst, Przemyslaw A. Filipek, Sabine Weys, Michael W. Hess, Herbert H. Lindner, Leopold Kremser et al. · 2013 · Journal of Biological Chemistry
  42. Subcellular Distribution and Activity of Mechanistic Target of Rapamycin in Aged Retinal Pigment Epithelium
    Bo Yu, P. Xu, Zhenyang Zhao, Jiyang Cai, P. Sternberg, Y. Chen · 2014 · Investigative Ophthalmology & Visual Science
  43. Diminished MTORC1-Dependent JNK Activation Underlies the Neurodevelopmental Defects Associated with Lysosomal Dysfunction
    Ching‐On Wong, Michela Palmieri, Jiaxing Li, Dmitry Akhmedov, Yufang Chao, Geoffrey T. Broadhead, Michael X. Zhu, Rebecca Berdeaux, Catherine A. Collins, Marco Sardiello et al. · 2015 · Cell Reports
  44. ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1
    Chengmin He, Zhi Yang, Ying Jin, Xiaoyang Qi, Jin Chu, Xiaoyuan Deng · 2018 · Frontiers in Physiology
  45. Mechanistic Target of Rapamycin Pathway in Epileptic Disorders
    JangKeun Kim, Jeong Ho Lee · 2019 · Journal of Korean Neurosurgical Society
  46. Autophagy Inhibition in BRAF-Driven Cancers
    Mona Foth, Martin McMahon · 2021 · Cancers
  47. How Cells Deal with the Fluctuating Environment: Autophagy Regulation under Stress in Yeast and Mammalian Systems
    Yuchen Lei, Yuxiang J. Huang, Xin Wen, Zhangyuan Yin, Zhihai Zhang, Daniel J. Klionsky · 2022 · Antioxidants
  48. CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
    Shasha Yin, Liu Liu, L. Ball, Ya-Long Wang, M. Bedford, S. Duncan, Hai-Zhen Wang, Wenjian Gan · 2023 · Cell Reports
  49. The rapid proximity labeling system PhastID identifies ATP6AP1 as an unconventional GEF for Rheb
    Ran Feng, Feng Liu, Ruofei Li, Zhifen Zhou, Zhuoheng Lin, Lin Song, Shengcheng Deng, Yingying Li, Baoting Nong, Ying Xia et al. · 2024 · Cell Research
  50. The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells
    Yue Wang, Ming Cui, Xiaoli Cai, Baodi Sun, Fabao Liu, Xiaodong Zhang, Lihong Ye · 2014 · Cancer Letters
  51. Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis.
    Jia Li, Shogo Wada, Lehn K. Weaver, C. Biswas, E. Behrens, Z. Arany · 2019 · JCI Insight
  52. Efficient delivery of small interfering RNAs targeting particular mRNAs into pancreatic cancer cells inhibits invasiveness and metastasis of pancreatic tumors
    Keisuke Taniuchi, Toshio Yawata, Makiko Tsuboi, Tetsuya Ueba, Toshiji Saibara · 2019 · Oncotarget
  53. ArfGAP1 inhibits mTORC1 lysosomal localization and activation
    De-Long Meng, Qianmei Yang, Chase H. Melick, B. Park, Ting-Sung Hsieh, Adna Curukovic, Mi-Hyeon Jeong, Jun-Mei Zhang, Nicholas G. James, Jenna L. Jewell · 2021 · EMBO Journal
  54. The Nuclear Import of Oncoprotein Hepatitis B X-interacting Protein Depends on Interacting with c-Fos and Phosphorylation of Both Proteins in Breast Cancer Cells
    Yingyi Zhang, Yu Zhao, Hang Li, Yinghui Li, Xiaoli Cai, Yu Shen, Hui Shi, Leilei Li, Qian Liu, Xiaodong Zhang et al. · 2013 · Journal of Biological Chemistry
  55. eIF4A inactivates TORC1 in response to amino acid starvation
    Foivos-Filippos Tsokanos, M. Albert, C. Demetriades, Kerstin Spirohn, M. Boutros, Aurelio A. Teleman · 2016 · EMBO Journal
  56. KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity
    Guokai Yan, Xiuzhi Li, Zilong Zheng, Weihua Gao, Changqing Chen, Xinkai Wang, Zhongyi Cheng, Jie Yu, Geng Zou, Muhammad Zahid Farooq et al. · 2022 · Autophagy
  57. Dynamin inhibitors block activation of mTORC1 by amino acids independently of dynamin
    Avinash K. Persaud, Yann Cormerais, Jacques Pouysségur, Daniela Rotin · 2018 · Journal of Cell Science
  58. Proteomic analyses reveal GNG12 regulates cell growth and casein synthesis by activating the Leu-mediated mTORC1 signaling pathway
    Chaochao Luo, Shengguo Zhao, Wenting Dai, Nan Zheng, Jiaqi Wang · 2018 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  59. Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease
    Simon Wheeler, Per Haberkant, Meenakshi Bhardwaj, Paige Tongue, Maria J. Ferraz, David Halter, Hein Sprong, Ralf Schmid, Johannes M. F. G. Aerts, Nikol Sullo et al. · 2019 · Neurobiology of Disease
  60. Lysosomal recycling of amino acids affects ER quality control
    Ryo Higuchi‐Sanabria, Koning Shen, Naame Kelet, Phillip Andrew Frankino, Jenni Durieux, Raz Bar‐Ziv, Cierra N. Sing, Enrique J. Garcia, Stefan Homentcovschi, Melissa Sanchez et al. · 2020 · Science Advances
  61. O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine
    Kibum Kim, H. Yoo, Byung-Gyu Kim, Sulhee Kim, Yulseung Sung, Ina Yoon, Ya-Chun Yu, Seung Joon Park, J. H. Kim, K. Myung et al. · 2022 · Nature Communications
  62. USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction.
    Alex Hertel, Ludovico Alves, Henrik Dutz, G. Tascher, F. Bonn, M. Kaulich, I. Dikič, S. Eimer, Florian Steinberg, A. Bremm · 2022 · Cell Reports
  63. Action Mechanism of Metformin and Its Application in Hematological Malignancy Treatments: A Review
    Yi Zhang, Fang Zhou, Jiaheng Guan, Lukun Zhou, Baoan Chen · 2023 · Biomolecules
  64. Preliminary Functional Assessment and Classification of DEPDC5 Variants Associated with Focal Epilepsy
    M. van Kranenburg, M. Hoogeveen-Westerveld, M. Nellist · 2015 · Human Mutation
  65. A role for TOR signaling at every stage of plant life
    Teagen D. Quilichini, Peng Gao, Prashant Kumar Pandey, Daoquan Xiang, Maozhi Ren, Raju Datla · 2019 · Journal of Experimental Botany
  66. Aminoacylation of Proteins: New Targets for the Old ARSenal.
    S. M. Jafarnejad, Sung-Hoon Kim, N. Sonenberg · 2018 · Cell Metabolism
  67. Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5
    Meng Shi, Bing Chen, Divyanshu Mahajan, Boon Kim Boh, Yan Zhou, Bamaprasad Dutta, Hieng Chiong Tie, Siu Kwan Sze, Geng Wu, Lei Lü · 2018 · Nature Communications
  68. Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
    Yuezhou Wang, Lei Zhang, Yanling Wei, Wei Huang, Li Li, Anan Wu, Anahita Dastur, Patricia Greninger, Walter M. Bray, Chen‐Song Zhang et al. · 2020 · Cell chemical biology
  69. New Insights into the Regulation of mTOR Signaling via Ca2+-Binding Proteins
    Yuna Amemiya, Masatoshi Maki, Hideki Shibata, Terunao Takahara · 2023 · International Journal of Molecular Sciences
  70. SNAT7 regulates mTORC1 via macropinocytosis
    Meng, Delong, Yang, Qianmei, Jeong, Mi-Hyeon, Curukovic, Adna, Tiwary, Shweta, Melick, Chase H., Lama-Sherpa, Tshering D., Wang, Huanyu, Huerta-Rosario, Mariela, Urquhart, Greg et al. · 2022 · Proceedings of the National Academy of Sciences
  71. PRL-3 activates mTORC1 in Cancer Progression
    Zu Ye, Abdul Qader Al-Aidaroos, Jung Eun Park, Hiu Fung Yuen, Shudong Zhang, Abhishek Kumar Gupta, Youbin Lin, Han‐Ming Shen, Qi Zeng · 2015 · Scientific Reports
  72. The oncoprotein HBXIP up-regulates FGF4 through activating transcriptional factor Sp1 to promote the migration of breast cancer cells
    Hui Shi, Yinghui Li, Guoxing Feng, Leilei Li, Runping Fang, Zhen Wang, Jie Qu, Peijian Ding, Xiaodong Zhang, Lihong Ye · 2016 · Biochemical and Biophysical Research Communications
  73. MiR‐145‐targeted HBXIP modulates human breast cancer cell proliferation
    Yang Jiang, Dan Wang, Hui Jun Ren, Ying Shi, Yufei Gao · 2018 · Thoracic Cancer
  74. TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTORC1 axis
    Wen Li, Yulan Li, Yetong Guan, Yingxin Du, Mingsheng Zhao, Xiaotong Chen, Faliang Zhu, Chun Hua Guo, Yufeng Jia, Yuan Li et al. · 2020 · Autophagy
  75. Growth and metabolic responses of grouper juveniles (Epinephelus coioides) fed diets containing varying levels of leucine
    Xingjian Niu, Xiaoli Qian, Hanmo Feng, Kui Yi, Li Dong, Weijun Chen, Jidan Ye · 2020 · Aquaculture
  76. The Late Endosomal Adaptor Molecule p14 (LAMTOR2) Regulates TGFβ1-Mediated Homeostasis of Langerhans Cells
    Florian Sparber, Christoph H. Tripp, Kerstin Komenda, Julia M. Scheffler, Björn E. Clausen, Lukas Alfons Huber, Nikolaus Romani, Patrizia Stoitzner · 2014 · Journal of Investigative Dermatology
  77. The Atg1-Tor pathway regulates yolk catabolism in Drosophila embryos
    Hallie Kuhn, Richelle Sopko, Margaret L. Coughlin, Norbert Perrimon, Tim J. Mitchison · 2015 · Development
  78. mTOR signalling: jack-of-all-trades
    Yassine El Hiani, Emmanuel Eroume A Egom, Xian‐Ping Dong · 2018 · Biochemistry and Cell Biology
  79. Aberrant hyper-expression of the RNA binding protein GIGYF2 in endothelial cells modulates vascular aging and function
    Fanglin Niu, Zhuozhuo Li, Yuanyuan Ren, Zi Li, Hua Guan, Yang Li, Yan Zhang, Yirong Li, Junle Yang, Qian Lü et al. · 2023 · Redox Biology
  80. FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1
    Xiaochun Wu, Lingling Zhao, Zhi Chen, Xin Ji, Xian-Feng Qiao, Ya-Ping Jin, Wei Liu · 2016 · PLoS ONE
  81. Regulation of mTORC1 activity by the Golgi apparatus
    Christian Makhoul, Paul A. Gleeson · 2021 · Faculty Reviews
  82. Amino Acids in Autophagy: Regulation and Function
    Zheng Shen, Guoyao Wu, Shaodong Guo · 2021 · Advances in experimental medicine and biology
  83. mTORC1 Crosstalk With Stress Granules in Aging and Age-Related Diseases
    Marti Cadena Sandoval, Alexander Martin Heberle, Ulrike Rehbein, Cecilia Barile, José M. Ramos Pittol, Kathrin Thedieck · 2021 · Frontiers in Aging
  84. The oncoprotein HBXIP promotes migration of breast cancer cells via GCN5-mediated microtubule acetylation
    Leilei Li, Bowen Liu, Xiaodong Zhang, Lihong Ye · 2015 · Biochemical and Biophysical Research Communications
  85. Ragulator—a multifaceted regulator of lysosomal signaling and trafficking
    Alexandria Colaço, Marja Jäättelä · 2017 · The Journal of Cell Biology
  86. Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP)
    Julia Brenmoehl, Christina Walz, Caroline Caffier, Elli Brosig, Michael Walz, Daniela Ohde, Nares Trakooljul, Martina Langhammer, Siriluck Ponsuksili, Klaus Wimmers et al. · 2021 · Cells
  87. The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB
    Zengli Zhang, Hongfeng Wang, Qifeng Ding, Yufei Xing, Delai Xu, Zhonghua Xu, Tong Zhou, Bin Qian, Chenghong Ji, Xue Pan et al. · 2017 · Biomedicine & Pharmacotherapy
  88. Cross Talk Networks of Mammalian Target of Rapamycin Signaling With the Ubiquitin Proteasome System and Their Clinical Implications in Multiple Myeloma
    Ruth Eichner, Vanesa Fernández‐Sáiz, Bianca‐Sabrina Targosz, Florian C. Bassermann · 2018 · International review of cytology
  89. Amino Acid–Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet
    S. Kimball, Suhana Ravi, Bradley S. Gordon, Michael D. Dennis, L. Jefferson · 2015 · Journal of NutriLife
  90. Novel tRNA function in amino acid sensing of yeast Tor complex1
    Yoshiaki Kamada · 2017 · Genes to Cells
  91. HEPES Activates a MiT/TFE-dependent Lysosomal-Autophagic Gene Network in Cultured Cells: A Call for Caution
    Tol, Marc J., van der Lienden, Martijn J.C., Gabriel, Tanit L., Hagen, Jacob J., Scheij, Saskia, Veenendaal, Tineke, Klumperman, Judith, Donker-Koopman, Wilma E., Verhoeven, Arthur J., Overkleeft, Hermen et al. · 2018 · Autophagy
  92. Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB
    Yoshitomo Hayama, Tetsuya Kimura, Yoshito Takeda, Shigeyuki Nada, Shohei Koyama, Hyota Takamatsu, Sujin Kang, Daisuke Ito, Yohei Maeda, Masayuki Nishide et al. · 2018 · The Journal of Immunology
  93. Survivin inhibits excessive autophagy in cancer cells but does so independently of its interaction with LC3
    Nicola J. Humphry, Sally P. Wheatley · 2018 · Biology Open
  94. Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth
    Sathish K. R. Padi, Neha Singh, J. Bearss, V. Olive, Jin H. Song, M. Cardó-Vila, A. Kraft, K. Okumura · 2019 · Proceedings of the National Academy of Sciences of the United States of America
  95. The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex
    Deng, Yilun, Qin, Yuejuan, Srikantan, Subramanya, Luo, Anqi, Cheng, Zi-Ming, Flores, Shahida K, Vogel, Kris S, Wang, Exing, Dahia, Patricia L M · 2018 · Human Molecular Genetics
  96. Environmental signaling through the mechanistic target of rapamycin complex 1
    Jason J. Workman, Hongfeng Chen, R. Laribee · 2014 · Cell Cycle
  97. Links between autophagy and disorders of glycogen metabolism – Perspectives on pathogenesis and possible treatments
    Benjamin L. Farah, Paul M. Yen, Dwight D. Koeberl · 2019 · Molecular Genetics and Metabolism
  98. N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression
    Yi Sun, Zhenfeng Guan, Qiu Sheng, Wanli Duan, Huacai Zhao, Jiancheng Zhou, Qian Deng, Xinqi Pei · 2022 · Cancer Letters
  99. Alcohol, Resistance Exercise, and mTOR Pathway Signaling: An Evidence-Based Narrative Review
    D. Levitt, Hui-Ying Luk, J. Vingren · 2022 · Biomolecules
  100. A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes
    Gholamreza Fazeli, Roni Levin‐Konigsberg, Michael Cory Bassik, Christian Stigloher, Ann Marie Wehman · 2023 · Current Biology