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Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling

Konno, Hiroyasu, Konno, Keiko, Barber, Glen N.·2013·Cell

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Crossref · 10.1016/j.cell.2013.09.049

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Citations

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Research works printed but not linked: 22

  1. Abe, 2013, STING recognition of cytoplasmic DNA instigates cellular defense, Mol. Cell, 50, 5, 10.1016/j.molcel.2013.01.039 · DOI
  2. Ablasser, 2013, cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING, Nature, 498, 380, 10.1038/nature12306 · DOI · Paper page
  3. Ahn, 2012, STING manifests self DNA-dependent inflammatory disease, Proc. Natl. Acad. Sci. USA, 109, 19386, 10.1073/pnas.1215006109 · DOI
  4. Alers, 2012, Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks, Mol. Cell. Biol., 32, 2, 10.1128/MCB.06159-11 · DOI · Paper page
  5. Alexander, 2011, The role of LKB1 and AMPK in cellular responses to stress and damage, FEBS Lett., 585, 952, 10.1016/j.febslet.2011.03.010 · DOI
  6. Blasius, 2010, Intracellular toll-like receptors, Immunity, 32, 305, 10.1016/j.immuni.2010.03.012 · DOI
  7. Civril, 2013, Structural mechanism of cytosolic DNA sensing by cGAS, Nature, 498, 332, 10.1038/nature12305 · DOI
  8. Diner, 2013, The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING, Cell Rep., 3, 1355, 10.1016/j.celrep.2013.05.009 · DOI · Paper page
  9. Fu, 2011, Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway, Proc. Natl. Acad. Sci. USA, 108, 1403, 10.1073/pnas.1018376108 · DOI
  10. Gall, 2012, Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease, Immunity, 36, 120, 10.1016/j.immuni.2011.11.018 · DOI · Paper page
  11. Hardie, 2012, AMP-activated protein kinase: a target for drugs both ancient and modern, Chem. Biol., 19, 1222, 10.1016/j.chembiol.2012.08.019 · DOI
  12. Jin, 2008, MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals, Mol. Cell. Biol., 28, 5014, 10.1128/MCB.00640-08 · DOI
  13. Kawai, 2011, Toll-like receptors and their crosstalk with other innate receptors in infection and immunity, Immunity, 34, 637, 10.1016/j.immuni.2011.05.006 · DOI · Paper page
  14. Kranzusch, 2013, Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity, Cell Rep., 3, 1362, 10.1016/j.celrep.2013.05.008 · DOI
  15. Saitoh, 2009, Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response, Proc. Natl. Acad. Sci. USA, 106, 20842, 10.1073/pnas.0911267106 · DOI · Paper page
  16. Sun, 2009, ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization, Proc. Natl. Acad. Sci. USA, 106, 8653, 10.1073/pnas.0900850106 · DOI
  17. Tamura, 2008, The IRF family transcription factors in immunity and oncogenesis, Annu. Rev. Immunol., 26, 535, 10.1146/annurev.immunol.26.021607.090400 · DOI · Paper page
  18. Tanaka, 2012, STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway, Sci. Signal., 5, ra20, 10.1126/scisignal.2002521 · DOI
  19. Tooze, 2010, Trafficking and signaling in mammalian autophagy, IUBMB Life, 62, 503, 10.1002/iub.334 · DOI
  20. Woodward, 2010, c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response, Science, 328, 1703, 10.1126/science.1189801 · DOI
  21. Zhang, 2013, Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING, Mol. Cell, 51, 226, 10.1016/j.molcel.2013.05.022 · DOI
  22. Zhong, 2008, The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation, Immunity, 29, 538, 10.1016/j.immuni.2008.09.003 · DOI

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Metadata

Authors
Konno, H., Konno, K., & Barber, G. N.
Venue
Cell
Publisher
Elsevier BV
Published
2013-10
Volume
155
Issue
3
Pages
688-698
ISSN
0092-8674
Cited by
687
References
7
Language
en

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