Super-Enhancers in the Control of Cell Identity and Disease

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Items 701–800 of 1,018

  1. BRD4 and MYC : power couple in transcription and disease
    Aparna Kotekar, Amit Kumar Singh, Ballachanda N. Devaiah · 2022 · FEBS Journal
  2. LSD1 Inhibition Disrupts Super-Enhancer–Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer
    Muqing Li, Mingyu Liu, Wanting Han, Zifeng Wang, Dong Gwan Han, Susan C. Patalano, Jill A. Macoska, Steven P. Balk, Housheng Hansen He, Eva Corey et al. · 2023 · Cancer Research
  3. Lipid-Induced Epigenomic Changes in Human Macrophages Identify a Coronary Artery Disease-Associated Variant that Regulates PPAP2B Expression through Altered C/EBP-Beta Binding
    Michael E. Reschen, Kyle J. Gaulton, Da Lin, Elizabeth J. Soilleux, Andrew J. Morris, Susan S. Smyth, Christopher A. O’Callaghan · 2015 · PLoS Genetics
  4. The structure based design of dual HDAC/BET inhibitors as novel epigenetic probes
    Stephen J. Atkinson, Peter E. Soden, Davina C. Angell, Marcus Bantscheff, Chun‐wa Chung, Kathryn A. Giblin, Nicholas N. Smithers, Rebecca C. Furze, Laurie J. Gordon, Gerard Drewes et al. · 2014 · MedChemComm
  5. An erythroid-specific ATP2B4 enhancer mediates red blood cell hydration and malaria susceptibility
    Samuel Lessard, Emily Stern Gatof, Mélissa Beaudoin, Patrick G. Schupp, Falak Sher, Adnan Ali, Sukhpal Prehar, Ryo Kurita, Yukio Nakamura, Esther Baena et al. · 2017 · Journal of Clinical Investigation
  6. Supercharging BRD4 with NUT in carcinoma
    Kyle P. Eagen, Christopher Alexander French · 2021 · Oncogene
  7. Androgen receptor and MYC equilibration centralizes on developmental super-enhancer
    Haiyang Guo, Yiming Wu, Mannan Nouri, Sándor Spisák, Joshua W. Russo, Adam G. Sowalsky, Mark M. Pomerantz, Zhao Wei, Keegan D. Korthauer, Ji-Heui Seo et al. · 2021 · Nature Communications
  8. New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine
    Hanli Xu, Shuye Lin, Ziyun Zhou, Duoduo Li, Xiting Zhang, Muhan Yu, Ruoyi Zhao, Yiheng Wang, Junru Qian, Xinyi Li et al. · 2023 · Cellular and Molecular Immunology
  9. Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features
    Kai Yan, Jaclyn Andricovich, Zhouhao Zeng, Jun Zhu, Alexandros Tzatsos, Weiqun Peng · 2018 · Nature Communications
  10. The principles that govern transcription factor network functions in stem cells
    Hitoshi Niwa · 2018 · Development
  11. Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation
    Maya Ghoussaini, Juliet D. French, Kyriaki Michailidou, Silje Nord, Jonathan Beesley, Sander Canisus, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Mahdi Moradi Marjaneh et al. · 2016 · The American Journal of Human Genetics
  12. Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors
    Sampada Kalan, Ramon Amat, Miriam Merzel Schachter, Nicholas P. Kwiatkowski, Brian J. Abraham, Yanke Liang, Tinghu Zhang, Calla M. Olson, Stéphane Larochelle, Richard A. Young et al. · 2017 · Cell Reports
  13. Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma
    Joseph Mandelbaum, Ilya A. Shestopalov, Rachel E. Henderson, Nicole Grace Chau, Birgit Knoechel, Michael J. Wick, Leonard Ira Zon · 2018 · The Journal of Experimental Medicine
  14. Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition
    So Maezawa, Akihiko Sakashita, Masashi Yukawa, Xiaoting Chen, Kazuki Takahashi, Kris G. Alavattam, Ippo Nakata, Matthew T. Weirauch, Artem Barski, Satoshi H. Namekawa · 2020 · Nature Structural & Molecular Biology
  15. SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression
    Guojun Hou, Isaac T. W. Harley, Xiaoming Lu, Tian Zhou, Ning Xu, Chao Yao, Yuting Qin, Ye Ouyang, Jianyang Ma, Xinyi Zhu et al. · 2021 · Nature Communications
  16. Genetics of autoimmune diseases: perspectives from genome-wide association studies
    Yuta Kochi · 2016 · International Immunology
  17. Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins
    Chan Zhou, Samuel R. York, Jennifer Y. Chen, Joshua V. Pondick, Daniel Motola, Raymond T. Chung, Alan C. Mullen · 2016 · Genome Medicine
  18. Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells
    Karmel A. Allison, Enikö Sajti, Jana G. Collier, David Gosselin, Ty D. Troutman, Erica Lyn Stone, Stephen Μ. Hedrick, Christopher K. Glass · 2016 · eLife
  19. LDB1-mediated enhancer looping can be established independent of mediator and cohesin
    Ivan V. Krivega, Ann Dean · 2017 · Nucleic Acids Research
  20. Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
    Sjur Reppe, Tonje Gulbrandsen Lien, Yi‐Hsiang Hsu, Vigdis T. Gautvik, Ole Kristoffer Olstad, Rona Yu, Hege G. Bakke, Robert Lyle, Marianne Kristiansen Kringen, Ingrid K. Glad et al. · 2017 · Epigenetics
  21. RUNX2 expression in thyroid and breast cancer requires the cooperation of three non-redundant enhancers under the control of BRD4 and c-JUN
    Valentina Sancisi, Gloria Manzotti, Mila Gugnoni, Teresa Rossi, Greta Gandolfi, Giulia Gobbi, Federica Torricelli, Francesca Catellani, Ítalo Faria do Valle, Daniel Remondini et al. · 2017 · Nucleic Acids Research
  22. Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates
    Pier Francesco Palamara, Laurent C. Francioli, Peter Wilton, Giulio Genovese, Alexander Gusev, Hilary K. Finucane, Sriram Sankararaman, Shamil R. Sunyaev, Paul I. W. de Bakker, John Wakeley et al. · 2015 · The American Journal of Human Genetics
  23. Epigenetic Switch between SOX2 and SOX9 Regulates Cancer Cell Plasticity
    Sheng‐Chieh Lin, Yu‐Ting Chou, Shih Sheng Jiang, Junn-Liang Chang, Chih-Hung Chung, Yu-Rung Kao, I‐Shou Chang, Cheng-Wen Wu · 2016 · Cancer Research
  24. A novel LSD1 inhibitor NCD38 ameliorates MDS-related leukemia with complex karyotype by attenuating leukemia programs via activating super-enhancers
    Noriko Sugino, Masahiro Kawahara, Goichi Tatsumi, Akinori Kanai, Hirotaka Matsui, Ryō Yamamoto, Yuya Nagai, S Fujii, Yayoi Shimazu, Masakatsu Hishizawa et al. · 2017 · Leukemia
  25. Linear convergence of CQ algorithms and applications in gene regulatory network inference
    Jinhua Wang, Yaohua Hu, Chong Li, Jen‐Chih Yao · 2017 · Inverse Problems
  26. Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells
    Rachael J. Werner, Bryant M. Schultz, Jacklyn M. Huhn, Jaroslav Jelı́nek, Jozef Madžo, Nora Engel · 2017 · Biology of Sex Differences
  27. The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia
    Shi Hao Tan, Wei Zhong Leong, Phuong Cao Thi Ngoc, Tze King Tan, Fatima Carla Bertulfo, Mei Chee Lim, Ömer An, Zhenhua Li, Allen Eng Juh Yeoh, Melissa J. Fullwood et al. · 2019 · Blood
  28. Beyond the Exome: The Non-coding Genome and Enhancers in Neurodevelopmental Disorders and Malformations of Cortical Development
    Elena Perenthaler, Soheil Yousefi, Eva Niggl, Tahsin Stefan Barakat · 2019 · Frontiers in Cellular Neuroscience
  29. Cancer-epigenetic function of the histone methyltransferase KMT2D and therapeutic opportunities for the treatment of KMT2D-deficient tumors
    Shilpa S. Dhar, Min Gyu Lee · 2021 · Oncotarget
  30. MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner
    Guojia Xie, Ji‐Eun Lee, Anna D. Senft, Young-Kwon Park, Younghoon Jang, Shreeta Chakraborty, Joyce J. Thompson, Kaitlin E. McKernan, Chengyu Liu, Todd S. Macfarlan et al. · 2023 · Nature Genetics
  31. Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer
    Ying Su, Ashim Subedee, Noga Bloushtain-Qimron, Virginia Savova, Marcin Krzystanek, Lewyn Li, Andriy Marusyk, Doris P. Tabassum, Alexander Zak, Mary Jo Flacker et al. · 2015 · Cell Reports
  32. The SOX9 upstream region prone to chromosomal aberrations causing campomelic dysplasia contains multiple cartilage enhancers
    Baojin Yao, Qing Kenneth Wang, C.-F. Liu, Pallavi Bhattaram, Wei Li, Timothy J. Mead, James F. Crish, Véronique Lefebvre · 2015 · Nucleic Acids Research
  33. Super Enhancers in Cancers, Complex Disease, and Developmental Disorders
    Adrienne R. Niederriter, Arushi Varshney, Stephen C.J. Parker, Donna M. Martin · 2015 · Genes
  34. Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs
    Isis Ricaño-Ponce, Daria V. Zhernakova, Patrick Deelen, Oscar Junhong Luo, Xingwang Li, Aaron J. Isaacs, Juha M Karjalainen, Jennifer Di Tommaso, Zuzanna Agnieszka Borek, Maria Magdalena Zorro et al. · 2016 · Journal of Autoimmunity
  35. E6 Protein Expressed by High-Risk HPV Activates Super-Enhancers of the EGFR and c-MET Oncogenes by Destabilizing the Histone Demethylase KDM5C
    Xiaohua Chen, Jun Xian Loo, Xin Shi, Wenjun Xiong, Yong Sheng Guo, Haiqiang Ke, Mingkun Yang, Yanping Jiang, Siyu Xia, Min Zhao et al. · 2018 · Cancer Research
  36. BET Bromodomain Proteins as Cancer Therapeutic Targets
    Shu, Shaokun, Polyak, Kornelia · 2016 · Cold Spring Harbor Symposia on Quantitative Biology
  37. Deconstruction of DNA Methylation Patterns During Myogenesis Reveals Specific Epigenetic Events in the Establishment of the Skeletal Muscle Lineage
    Elvira Carrió, Anna Díez-Villanueva, Sergio Lois, Izaskun Mallona, Ildefonso Cases, Marta Forn, Miguel Angel Peinado, Mònica Suelves · 2015 · Stem Cells
  38. Enhancer RNA: What we know and what we can achieve
    Zhenzhen Han, Wei Li · 2022 · Cell Proliferation
  39. Epigenetics in T‐cell acute lymphoblastic leukemia
    Sofie Peirs, Joni Van der Meulen, Inge Van de Walle, Tom Taghon, Frank Speleman, Bruce Graham Poppe, Pieter Van Vlierberghe · 2014 · Immunological Reviews
  40. Preclinical Efficacy and Molecular Mechanism of Targeting CDK7-Dependent Transcriptional Addiction in Ovarian Cancer
    Zhenfeng Zhang, Huixin Peng, Xiaojie Wang, Xia Yin, Pengfei Ma, Ying Jing, Mei‐Chun Cai, Jin Liu, Meiying Zhang, Shengzhe Zhang et al. · 2017 · Molecular Cancer Therapeutics
  41. Dynamic evolution of regulatory element ensembles in primate CD4+ T cells
    Charles G. Danko, Lauren A. Choate, Brooke A. Marks, Edward J. Rice, Zhong Wang, Tinyi Chu, Andre L. Martins, Noah Dukler, Scott Alexander Coonrod, Elia D. Tait Wojno et al. · 2018 · Nature Ecology & Evolution
  42. Epigenomes in Cardiovascular Disease
    Manuel Rosa‐Garrido, Douglas J. Chapski, Thomas M. Vondriska · 2018 · Circulation Research
  43. Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits
    Paola Giusti‐Rodríguez, Patrick F. Sullivan · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  44. Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation
    Wang, Eric, Zhou, Hua, Nadorp, Bettina, Cayanan, Geraldine, Chen, Xufeng, Yeaton, Anna H., Nomikou, Sofia, Witkowski, Matthew T., Narang, Sonali, Kloetgen, Andreas et al. · 2021 · Cell Stem Cell
  45. BET inhibitors in the treatment of hematologic malignancies: current insights and future prospects
    Munshi, Hidayatullah, Abedin, Sameem, Boddy, Craig · 2016 · OncoTargets and Therapy
  46. Long noncoding RNAs in organogenesis: making the difference
    Phillip Grote, Bernhard G. Herrmann · 2015 · Trends in Genetics
  47. Genomic Effects of the Vitamin D Receptor: Potentially the Link between Vitamin D, Immune Cells, and Multiple Sclerosis
    Ming Shian Lu, Bruce V. Taylor, Heinrich Körner · 2018 · Frontiers in Immunology
  48. Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA
    Jūlı́us Guðmundsson, Jon Karl Sigurdsson, Lilja Stefánsdóttir, Bjarni Agnar Agnarsson, Helgi J. Ísaksson, Ólafur Andri Stefánsson, Sigurjon Axel Gudjonsson, Daniel Fannar Gudbjartsson, Gísli Másson, Michael L. Frigge et al. · 2018 · Nature Communications
  49. Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function
    Mary Lauren Benton, Sai Charan Talipineni, Dennis Kostka, John A. Capra · 2019 · BMC Genomics
  50. Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome
    Austin L. Brown, Adam J. de Smith, Vincent Ulysses Gant, Wenjian Yang, Michael E. Scheurer, Kyle M. Walsh, Jonathan M. Chernus, Noah A. Kallsen, Shanna A. Peyton, Gareth E. Davies et al. · 2019 · Blood
  51. Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1
    Ying Ying, Yejun Wang, Xiaoyan Huang, Yanmei Sun, Junbao Zhang, Meiqi Li, Junhui Zeng, Maolin Wang, Wenjun Xiao, Lan Zhong et al. · 2019 · Oncogene
  52. Mechanisms of Transcription Elongation Factor DSIF (Spt4–Spt5)
    Tim-Michael Decker · 2020 · Journal of Molecular Biology
  53. Recurrent integration of human papillomavirus genomes at transcriptional regulatory hubs
    Alix Warburton, Tovah E. Markowitz, Joshua P. Katz, James M. Pipas, Alison A. McBride · 2021 · npj Genomic Medicine
  54. A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes
    Matthieu Dos Santos, Stéphanie Backer, Frédéric Aurade, Matthew Man-Kin Wong, Maud Wurmser, Rémi Pierre, Francina Langa Vives, Marcio Do Cruzeiro, Alain Schmitt, Jean‐Paul Concordet et al. · 2022 · Nature Communications
  55. TBX20 Improves Contractility and Mitochondrial Function During Direct Human Cardiac Reprogramming
    Yawen Tang, Sajesan Aryal, Xiaoxiao Geng, Xinyue Zhou, Vladimir G. Fast, Jianyi Jay Zhang, Rui Lu, Yang Zhou · 2022 · Circulation
  56. The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ
    Masashi Watanabe, Hidehisa Takahashi, Yasushi Saeki, Takashi J. Ozaki, Shihori Itoh, Masanobu Suzuki, Wataru Mizushima, Keiji Tanaka, Shigetsugu Hatakeyama · 2015 · eLife
  57. Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation
    Xiang Xiao, Yihui Fan, Junhui Li, Xiaolong Zhang, Xiaohua Lou, Yaling Dou, Xiaomin Shi, Peixiang Lan, Yue Xiao, Laurie J. Minze et al. · 2018 · The Journal of Experimental Medicine
  58. Octopus-toolkit: a workflow to automate mining of public epigenomic and transcriptomic next-generation sequencing data
    Taemook Kim, Hogyu David Seo, Lothar G. Hennighausen, Daeyoup Lee, Keunsoo Kang · 2018 · Nucleic Acids Research
  59. Enhancers: bridging the gap between gene control and human disease
    Jaret M. Karnuta, Peter C. Scacheri · 2018 · Human Molecular Genetics
  60. Studying Transcriptional Enhancers: The Founder Fallacy, Validation Creep, and Other Biases
    Marc S. Halfon · 2018 · Trends in Genetics
  61. Genomic Enhancers in Brain Health and Disease
    Nancy V. N. Carullo, Jeremy J. Day · 2019 · Genes
  62. The hyper-activation of transcriptional enhancers in breast cancer
    Qinglan Li, Dan-Ya Wang, Lingao Ju, Jie Yao, Chuan Gao, Pin‐Ji Lei, Lianyun Li, Xiaolu Zhao, Min Wu · 2019 · Clinical Epigenetics
  63. The “ART” of Epigenetics in Melanoma: From histone “Alterations, to Resistance and Therapies”
    Thomas Strub, Robert Ballotti, Corine Bertolotto · 2020 · Theranostics
  64. Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53
    Tamara Potapova, Christopher W. Seidel, Andrew Box, Giulia Irene Rancati, Rong Li · 2016 · Molecular Biology of the Cell
  65. The role of distinct BRD4 isoforms and their contribution to high-grade serous ovarian carcinoma pathogenesis
    Ana Luiza Drumond‐Bock, Magdalena Bieniasz · 2021 · Molecular Cancer
  66. Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases
    Carolina Makowski, Dennis van der Meer, Weixiu Dong, Hao Wang, Yan Wu, Jingjing Zou, Cin Liu, Sara B. Rosenthal, Donald J. Hagler, Chun Chieh Fan et al. · 2022 · Science
  67. BRD4 regulates Nanog expression in mouse embryonic stem cells and preimplantation embryos
    Wei Liu, Paula Stein, Xuewen Cheng, Wenli Yang, N-Y Shao, Edward E. Morrisey, R M Schultz, J You · 2014 · Cell Death and Differentiation
  68. Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles
    Paloma Cejas, Lewyn Li, Nicholas K. O’Neill, Melissa Duarte, Prakash K. Rao, Michaela Bowden, Chensheng Willa Zhou, Marta Mendiola, Emilio Burgos, Jaime Feliú et al. · 2016 · Nature Medicine
  69. Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia
    Sofie Peirs, Viktoras Frismantas, Filip Matthijssens, Wouter Van Loocke, Tim Pieters, Niels Vandamme, Béatrice Lintermans, Maria Pamela Dobay, Geert Berx, Bruce Graham Poppe et al. · 2017 · Leukemia
  70. A transcribed enhancer dictates mesendoderm specification in pluripotency
    Michael Alexanian, Daniel Maric, Stephen Philip Jenkinson, Marco Mina, Clayton E. Friedman, Ching-Chia Ting, Rudi Micheletti, Isabelle Plaisance, Mohamed Nemir, Damien Maison et al. · 2017 · Nature Communications
  71. Approaches and advances in the genetic causes of autoimmune disease and their implications
    Inshaw, Jamie R. J., Cutler, Antony J., Burren, Oliver S., Stefana, M. Irina, Todd, John A. · 2018 · Nature Immunology
  72. The anti-cancer drugs curaxins target spatial genome organization
    Omar L. Kantidze, Artem V. Luzhin, Ekaterina V. Nizovtseva, Alfiya F. Safina, Maria E. Valieva, Arkadiy K. Golov, Artem K. Velichko, Alexander V. Lyubitelev, Alexey V. Feofanov, Katerina V. Gurova et al. · 2019 · Nature Communications
  73. Global Quantitative Mapping of Enhancers in Rice by STARR-Seq
    Jialei Sun, Na He, Longjian Niu, Yingzhang Huang, Wei Shen, Yuedong Zhang, Li Li, Chunhui Hou · 2019 · Genomics Proteomics & Bioinformatics
  74. Molecular genetic contributions to self-rated health
    Sarah E. Harris, Saskia P. Hagenaars, Gail Davies, William David Hill, David C M Liewald, Stuart James Ritchie, Riccardo Emilio Marioni, Cathie L. M. Sudlow, Joanna Marguerite Wardlaw, Andrew Mark McIntosh et al. · 2016 · International Journal of Epidemiology
  75. Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain
    Aslihan Dincer, David P. Gavin, Ke Xu, B Zhang, Joel T. Dudley, Eric E. Schadt, Schahram Akbarian · 2015 · Translational Psychiatry
  76. Influence of justice, culture and love of money towards ethical perception on tax evasion with gender as moderating variable
    Dodik Ariyanto, Gusti Ayu Putu Weni Andayani, I Gusti Ayu Made Asri Dwija Putri · 2020 · Journal of Money Laundering Control
  77. Mechanisms of Enhancer-Promoter Interactions in Higher Eukaryotes
    Pavel G Georgiev, Olga Kyrchanova · 2021 · International Journal of Molecular Sciences
  78. Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma
    Mark W. Zimmerman, Adam David Durbin, Shuning He, Felix Oppel, Hui Shi, Ting Tao, Zhaodong Li, Alla Berezovskaya, Yu Liu, Jinghui Zhang et al. · 2021 · Science Advances
  79. The chromatin signatures of enhancers and their dynamic regulation
    Amandine Barral, Jérôme Déjardin · 2023 · Nucleus
  80. Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells
    Hideyuki Yoshida, Kushagra Bansal, Uwe Schaefer, Trevor D. Chapman, Inmaculada Rioja, Irina Proekt, Mark Stuart Anderson, Rab K. Prinjha, Alexander Tarakhovsky, Christophe O. Benoist et al. · 2015 · Proceedings of the National Academy of Sciences
  81. Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes
    Jason S. Weinstein, Kimberly Lezon-Geyda, Yelena D. Maksimova, Samuel Craft, Yaoping Zhang, Mack Y. Su, Vincent Schulz, Joseph E. Craft, Patrick G. Gallagher · 2014 · Blood
  82. A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates
    Jean-Louis Plouhinec, Sofía Medina-Ruiz, Caroline Borday, Elsa Bernard, Jean‐Philippe Vert, Michael B. Eisen, Richard M. Harland, Anne Helene Monsoro-Burq · 2017 · PLoS Biology
  83. Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth
    Chunyan Ren, Guangtao Zhang, Fangbin Han, Shibo Fu, Yingdi Cao, Fan Zhang, Qiang Zhang, Jamel Eddine Meslamani, Yaoyao Xu, Donglei Ji et al. · 2018 · Proceedings of the National Academy of Sciences
  84. EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis
    Guillermo Peluffo, Ashim Subedee, Nicholas W. Harper, Natalie L. Kingston, Bojana Jovanović, Felipe N. Flores, Laura E. Stevens, Francisco Ferro de Beça, Anne C. Trinh, Chandra Sekhar Reddy Chilamakuri et al. · 2019 · Cancer Research
  85. PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma
    Melusine Bleu, Swann Gaulis, Rui Lopes, Kathleen Sprouffske, Verena Apfel, Sjoerd J.B. Holwerda, Marco Pregnolato, Umut Yildiz, Valentina Cordo’, Antonella F. M. Dost et al. · 2019 · Nature Communications
  86. Group sparse optimization via l p,q regularization
    Yaohua Hu, Chong Li, Kaiwen Meng, Jing Qin, Xiaoqi Yang · 2017 · PolyU Institutional Research Archive (Hong Kong Polytechnic University)
  87. Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51
    Idit Hazan, Jonathan Monin, Britta A. M. Bouwman, Nicola Crosetto, Rami I. Aqeilan · 2019 · Cell Reports
  88. Targeting Super-Enhancer–Associated Oncogenes in Osteosarcoma with THZ2, a Covalent CDK7 Inhibitor
    Jiajun Zhang, Weihai Liu, Changye Zou, Zhiqiang Zhao, Yuanying Lai, Zhi Shi, Xianbiao Xie, Gang Huang, Yongqian Wang, Xuelin Zhang et al. · 2020 · Clinical Cancer Research
  89. UNBRANCHED3 Expression and Inflorescence Development is Mediated by UNBRANCHED2 and the Distal Enhancer, KRN4, in Maize
    Yanfang Du, Lei Liu, Yong Peng, Manfei Li, Yunfu Li, Dan Liu, Xingwang Li, Zuxin Zhang · 2020 · PLoS Genetics
  90. Transcription factors: building hubs in the 3D space
    Dafne Campigli Di Giammartino, Alexander Polyzos, Effie Apostolou · 2020 · Cell Cycle
  91. BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity
    Eui‐Jun Kim, Peng Liu, Shengjie Zhang, Kristine Donahue, Yidan Wang, Jennifer L. Schehr, Serena K. Wolfe, Amber Dickerson, Li Lü, Lixin Rui et al. · 2021 · Nucleic Acids Research
  92. Pregnancy, preeclampsia and maternal aging: From epidemiology to functional genomics
    Eliza C. Miller, Ashley Wilczek, Natalie Ann Bello, Sarah E. Tom, Ronald J. Wapner, Yousin Suh · 2021 · Ageing Research Reviews
  93. The Fra-1/AP-1 Oncoprotein: From the “Undruggable” Transcription Factor to Therapeutic Targeting
    Laura Casalino, Francesco Talotta, Amelia Cimmino, Pasquale Verde · 2022 · Cancers
  94. Lactate accumulation induces H4K12la to activate super-enhancer-driven RAD23A expression and promote niraparib resistance in ovarian cancer
    Bingfeng Lu, Shuo Chen, Xue Guan, Xi Chen, Yuping Du, Jing Yuan, Jielin Wang, Qinghua Wu, Lingfeng Zhou, Xiangchun Huang et al. · 2025 · Molecular Cancer
  95. Causal role of histone acetylations in enhancer function
    Madapura M. Pradeepa · 2016 · Transcription
  96. The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells
    Semir Beyaz, Ji Hyung Kim, Luca Pinello, Michael E. Xifaras, Yu Hu, Jialiang Huang, Marc A. Kerenyi, Partha Pratim Das, R. Anthony Barnitz, Aurélie Hérault et al. · 2016 · Nature Immunology
  97. Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer
    Hui-Yi Wang, Qiaoyun Long, Shan‐Bo Tang, Qiong Xiao, Chuan Gao, Quanyi Zhao, Qinglan Li, Mei Ye, Lei Zhang, Lianyun Li et al. · 2019 · Nucleic Acids Research
  98. The regulatory landscapes of developmental genes
    Christopher Chase Bolt, Denis Duboule · 2020 · Development
  99. ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis
    Wei Zhong Leong, Shi Hao Tan, Phuong Cao Thi Ngoc, Stella Amanda, Alice Wei Yee Yam, Wei‐Siang Liau, Zhiyuan Gong, Lee N. Lawton, Daniel Geoffrey Tenen, Takaomi Sanda · 2017 · Genes & Development
  100. Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases
    Yue Li, M Kellis · 2016 · Nucleic Acids Research