Super-Enhancers in the Control of Cell Identity and Disease

Cited by (1,018)

Items 301–400 of 1,018

1. Spatiotemporal DNA methylome dynamics of the developing mouse fetus
   Yupeng He, Manoj Hariharan, David U. Gorkin, Diane E. Dickel, Chongyuan Luo, Rosa Castanon, Joseph R. Nery, Ah Young Lee, Yuan Zhao, Hui Huang et al. · 2020 · Nature
2. LncRNA DSCAM-AS1 interacts with YBX1 to promote cancer progression by forming a positive feedback loop that activates FOXA1 transcription network
   Yin Zhang, Yongxin Huang, Dan-Lan Wang, Bing Yang, Haiyan Yan, Lehang Lin, Yun Li, Jie Chen, Li‐Min Xie, Yongsheng Huang et al. · 2020 · Theranostics
3. A compendium and comparative epigenomics analysis of cis-regulatory elements in the pig genome
   Yunxia Zhao, Ye Hou, Yueyuan Xu, Yu Luan, Huanhuan Zhou, Xiaolong Qi, Mingyang Hu, Daoyuan Wang, Zhangxu Wang, Yuhua Fu et al. · 2021 · Nature Communications
4. High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq
   Vanhille, Laurent, Griffon, Aurélien, Maqbool, Muhammad Ahmad, Zacarias-Cabeza, Joaquin, Dao, Lan T.M., Fernandez, Nicolas, Ballester, Benoit, Andrau, Jean Christophe, Spicuglia, Salvatore · 2015 · Nature Communications
5. Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer
   Yejing Ge, Elaine V. Fuchs · 2018 · Nature Reviews Genetics
6. Occupancy maps of 208 chromatin-associated proteins in one human cell type
   Partridge, E. Christopher, Chhetri, Surya B., Prokop, Jeremy W., Ramaker, Ryne C., Jansen, Camden S., Goh, Say-Tar, Mackiewicz, Mark, Newberry, Kimberly M., Brandsmeier, Laurel A., Meadows, Sarah K. et al. · 2020 · Nature
7. Enhancer Malfunction in Cancer
   Hans‐Martin Herz, Deqing Hu, Ali Shilatifard · 2014 · Molecular Cell
8. Enhancer Logic and Mechanics in Development and Disease
   Ryan A. Rickels, Ali Shilatifard · 2018 · Trends in Cell Biology
9. Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis
   Unnur Styrkársdóttir, Sigrún H. Lund, Guðmar Þorleifsson, Florian Zink, Ólafur Andri Stefánsson, Jon Karl Sigurdsson, Kristinn Juliusson, Kristbjörg Bjarnadóttir, Sara Sigurbjörnsdóttir, Stefan Jonsson et al. · 2018 · Nature Genetics
10. Direct observation of a condensate effect on super-enhancer controlled gene bursting
    Manyu Du, Simon Hendrik Stitzinger, Jan-Hendrik Spille, Won‐Ki Cho, Choongman Lee, Mohammed Hijaz, Andrea Quintana, Ibrahim I. Cissé · 2024 · Cell
11. Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin
    Ing-Simmons, Elizabeth, Seitan, Vlad C., Faure, Andre J., Flicek, Paul, Carroll, Thomas, Dekker, Job, Fisher, Amanda G., Lenhard, Boris, Merkenschlager, Matthias · 2015 · Genome Research
12. Stem Cell Heterogeneity and Plasticity in Epithelia
    Giacomo Donati, Fiona M. Watt · 2015 · Cell stem cell
13. Inhibition of bromodomain and extra-terminal proteins (BET) as a potential therapeutic approach in haematological malignancies: emerging preclinical and clinical evidence
    Aristeidis Chaidos, Valentina S. Caputo, Anastasios Karadimitris · 2015 · Therapeutic Advances in Hematology
14. Acute BAF perturbation causes immediate changes in chromatin accessibility
    Sandra Schick, Sarah Grosche, Katharina Eva Kohl, Danica Drpic, Martin G. Jaeger, Nara Marella, Hana Imrichová, Jung-Ming G. Lin, Gerald Hofstätter, Michael K. Schuster et al. · 2021 · Nature Genetics
15. Nucleoporin-mediated regulation of cell identity genes
    Arkaitz Ibarra, Christopher W. Benner, Swati Tyagi, Jonah Cool, Martin W. Hetzer · 2016 · Genes & Development
16. Complex Compound Inheritance of Lethal Lung Developmental Disorders Due to Disruption of the TBX-FGF Pathway
    Justyna A. Karolak, Marie Vincent, Gail H. Deutsch, Tomasz Gambin, Benjamin Cogné, Olivier Pichon, Francesco Vetrini, Heather C. Mefford, Jennifer N. Dines, Katie L. Golden‐Grant et al. · 2019 · The American Journal of Human Genetics
17. A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma
    Nikki K. Lytle, Lesley Paige Ferguson, Nirakar Rajbhandari, Kathryn L. Gilroy, Raymond G. Fox, Anagha J. Deshpande, Christian M. Schürch, Michael Hamilton, Neil Robertson, Wei Lin et al. · 2019 · Cell
18. A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma
    Tim van Groningen, Nurdan Akogul, Ellen M. Westerhout, Alvin Chan, Nancy E. Hasselt, Danny A. Zwijnenburg, Marloes E.C. Broekmans, Peter J.M. Stroeken, Franciska Haneveld, Gerrit K. J. Hooijer et al. · 2019 · Nature Communications
19. Targeting transcription cycles in cancer
    Stephin J. Vervoort, Jennifer R. Devlin, Nicholas P. Kwiatkowski, Mingxing Teng, Nathanael S. Gray, Ricky W. Johnstone · 2021 · Nature reviews. Cancer
20. Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence
    Sen, Payel, Lan, Yemin, Li, Catherine Y., Sidoli, Simone, Donahue, Greg, Dou, Zhixun, Frederick, Brian, Chen, Qijun, Luense, Lacey J., Garcia, Benjamin A. et al. · 2019 · Molecular Cell
21. Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation
    Evelyn N. Kouwenhoven, Martin Oti, Hanna Niehues, Simon J. van Heeringen, Joost Schalkwijk, Hendrik G. Stunnenberg, Hans van Bokhoven, Huiqing Zhou · 2015 · EMBO Reports
22. Super-enhancers in cancer
    Palaniraja Thandapani · 2019 · Pharmacology & Therapeutics
23. The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection
    Buganim, Yosef, Markoulaki, Styliani, van Wietmarschen, Niek, Hoke, Heather, Wu, Tao, Ganz, Kibibi, Akhtar-Zaidi, Batool, He, Yupeng, Abraham, Brian J., Porubsky, David et al. · 2014 · Cell Stem Cell
24. EnhancerAtlas: a resource for enhancer annotation and analysis in 105 human cell/tissue types
    Tianshun Gao, Bing He, Sheng Liu, Heng Zhu, Kai Tan, Jiang X. Qian · 2016 · Bioinformatics
25. AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies
    Garrett W. Rhyasen, Maureen Mertens Hattersley, Yi Yao, Austin M. Dulak, Wenxian Wang, Philip Petteruti, Ian L. Dale, Scott Boiko, Tony Cheung, Jingwen Zhang et al. · 2016 · Molecular Cancer Therapeutics
26. Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6C low Monocytes while Preserving Macrophage Gene Function
    Graham D. Thomas, Richard N. Hanna, Neelakatan T. Vasudevan, Anouk A.J. Hamers, Casey E. Romanoski, Sara McArdle, Kevin D. Ross, Amy Blatchley, Deborah Yoakum, Bruce A. Hamilton et al. · 2016 · Immunity
27. Molecular diversification of regulatory T cells in nonlymphoid tissues
    Joanna R. DiSpirito, David Zemmour, Deepshika Ramanan, Jun Cho, Rapolas Žilionis, Allon Moshe Klein, Christophe O. Benoist, Diane J. Mathis · 2018 · Science Immunology
28. Small-molecule targeting of brachyury transcription factor addiction in chordoma
    Tanaz Sharifnia, Mathias J. Wawer, Ting Chen, Qingyuan Huang, Barbara A. Weir, Ann E. Sizemore, Matthew A. Lawlor, Amy B. Goodale, Glenn S. Cowley, Francisca Vázquez et al. · 2019 · Nature Medicine
29. Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling
    Feng Xie, Xiaoxue Zhou, Peng Su, Heyu Li, Yifei Tu, Jinjin Du, Chen Pan, Wei Dong Xiang, Min Zheng, Ke Jin et al. · 2022 · Nature Communications
30. Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
    EMBRACE, Dunning, Alison M, GEMO Study Collaborators, HEBON, kConFab Investigators, Michailidou, Kyriaki, Kuchenbaecker, Karoline B, Thompson, Deborah, French, Juliet D, Beesley, Jonathan et al. · 2016 · Nature Genetics
31. Regulation ofMYCgene expression by aberrant Wnt/β-catenin signaling in colorectal cancer
    Sherri A. Rennoll · 2015 · World Journal of Biological Chemistry
32. Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma
    Berkley E. Gryder, Silvia Pomella, Carly M. Sayers, Xiaoli Wu, Young Song, Anna M. Chiarella, Sukriti Bagchi, Hsien-Chao Chou, Ranuka Sinniah, Ashley Walton et al. · 2019 · Nature Genetics
33. Positively selected enhancer elements endow osteosarcoma cells with metastatic competence
    Morrow, James J, Bayles, Ian, Funnell, Alister P W, Miller, Tyler E, Saiakhova, Alina, Lizardo, Michael M, Bartels, Cynthia F, Kapteijn, Maaike Y, Hung, Stevephen, Mendoza, Arnulfo et al. · 2018 · Nature Medicine
34. Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells
    Olivia I. Koues, Patrick L. Collins, Marina Cella, Michelle L. Robinette, Sofia I. Porter, Sarah Pyfrom, Jacqueline E. Payton, Marco Colonna, Eugene M. Oltz · 2016 · Cell
35. A disease-associated gene desert directs macrophage inflammation through ETS2
    Christina T. Stankey, Christophe Bourges, Lea-Maxie Haag, Tabitha Turner‐Stokes, A. P. Piedade, Christopher Palmer-Jones, Ilenia Papa, Mariana Silva dos Santos, Q. Zhang, Andrew J. Cameron et al. · 2024 · Nature
36. Genomic Perspectives of Transcriptional Regulation in Forebrain Development
    Nord, Alex S., Pattabiraman, Kartik, Visel, Axel, Rubenstein, John L.R. · 2015 · Neuron
37. Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation
    Shun Hang Chan, Yin Tang, Liyun Miao, Hiba Darwich‐Codore, Charles E. Vejnar, Jean-Denis Beaudoin, Damir Musaev, Juan Pablo Fernández, Maria D.J. Benitez, Ariel Bazzini et al. · 2019 · Developmental Cell
38. Epigenomic Comparison Reveals Activation of “Seed” Enhancers during Transition from Naive to Primed Pluripotency
    Daniel C. Factor, Olivia Corradin, Gabriel E. Zentner, Alina Saiakhova, Lingyun Song, Josh G. Chenoweth, Ronald D.G. McKay, Gregory E. Crawford, Peter C. Scacheri, Paul J. Tesar · 2014 · Cell stem cell
39. ARID1A loss in cancer: Towards a mechanistic understanding
    Radhika Mathur · 2018 · Pharmacology & Therapeutics
40. Cistrome Cancer: A Web Resource for Integrative Gene Regulation Modeling in Cancer
    Shenglin Mei, Clifford A. Meyer, Rongbin Zheng, Qian Qin, Qiu Wu, Peng Jiang, Bo Li, Xiaohui Shi, Binbin Wang, Jing‐Yu Fan et al. · 2017 · Cancer Research
41. CDK9 inhibitors in acute myeloid leukemia
    Silvia Boffo, Angela Damato, Luigi Alfano, Antonio Giordano · 2018 · Journal of Experimental & Clinical Cancer Research
42. Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13
    Mei Zeng, Nicholas P. Kwiatkowski, Tinghu Zhang, Behnam Nabet, Mousheng Xu, Yanke Liang, Chunshan Quan, Jinhua Wang, Mingfeng Hao, Sangeetha S. Palakurthi et al. · 2018 · eLife
43. Phase separation of OCT4 controls TAD reorganization to promote cell fate transitions
    Jia Wang, Haopeng Yu, Qian Ma, Pengguihang Zeng, Dan‐Ya Wu, Yingping Hou, Xinyi Liu, Lumeng Jia, Jun Sun, Yilong Chen et al. · 2021 · Cell stem cell
44. BET Epigenetic Reader Proteins in Cardiovascular Transcriptional Programs
    Patrícia Cristine Borck, Lian‐Wang Guo, Jorge Plutzky · 2020 · Circulation Research
45. Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions
    Xiong Ji, Daniel Benjamin Dadon, Brian J. Abraham, Tong Ihn Lee, Rudolf Jaenisch, James E. Bradner, Richard A. Young · 2015 · Proceedings of the National Academy of Sciences
46. Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner
    Sung-Hak Kim, Ravesanker Ezhilarasan, Emma S. Phillips, Daniel Gallego‐Perez, Amanda E Sparks, David Taylor, Katherine J. Ladner, Takuya Furuta, Hemragul Sabit, Rishi Raj Chhipa et al. · 2016 · Cancer Cell
47. Aberrant Super‐Enhancer Landscape in Human Hepatocellular Carcinoma
    Felice Ho‐Ching Tsang, Cheuk‐Ting Law, Tsz Ching Chloe Tang, Carol Lai‐Hung Cheng, Don Wai‐Ching Chin, Vincy Tam, Lai Wei, Carmen Chak‐Lui Wong, Irene Oi‐Lin Ng, Chun‐Ming Wong · 2019 · Hepatology
48. LncRNA NEAT1 controls the lineage fates of BMSCs during skeletal aging by impairing mitochondrial function and pluripotency maintenance
    Hengguo Zhang, Rongyao Xu, Bang Li, Zhili Xin, Ziji Ling, Weiwen Zhu, Xiang Li, Ping Zhang, Yu Fu, Jiyu Chen et al. · 2021 · Cell Death and Differentiation
49. The Role of Notch Receptors in Transcriptional Regulation
    Hongfang Wang, Chongzhi Zang, X. Shirley Liu, Jon Christopher Aster · 2014 · Journal of Cellular Physiology
50. BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency
    Behdad Afzali, Juha Grönholm, Jana Vandrovcová, Carl O'Brien, Hong‐Wei Sun, Ine Vanderleyden, Fred P. Davis, Ahmad Khoder, Yu Zhang, Ahmed Nabil Hegazy et al. · 2017 · Nature Immunology
51. Enhancer release and retargeting activates disease-susceptibility genes
    Oh, Soohwan, Shao, Jiaofang, Mitra, Joydeep, Xiong, Feng, D’Antonio, Matteo, Wang, Ruoyu, Garcia-Bassets, Ivan, Ma, Qi, Zhu, Xiaoyu, Lee, Joo-Hyung et al. · 2021 · Nature
52. DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation
    Laura Godfrey, Nicholas T. Crump, Ross Thorne, I‐Jun Lau, Emmanouela Repapi, Dimitra Dimou, Alastair Smith, Joe R. Harman, Jelena M. Telenius, A. Marieke Oudelaar et al. · 2019 · Nature Communications
53. Cell-type-specific 3D epigenomes in the developing human cortex
    Michael Song, Mark-Phillip Pebworth, Xiaoyu Yang, Armen Abnousi, Changxu Fan, Jia Wen, Jonathan D. Rosen, Mayank N. K. Choudhary, Xiekui Cui, Ian Richard Jones et al. · 2020 · Nature
54. Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns
    Xiaofei Yang, Lin Gao, Shihua Zhang · 2016 · Briefings in Bioinformatics
55. Tracing dynamic changes of DNA methylation at single cell resolution
    Stelzer, Yonatan, Shivalila, Chikdu Shakti, Soldner, Frank, Markoulaki, Styliani, Jaenisch, Rudolf · 2015 · Cell
56. Beating the odds: BETs in disease
    Chenyi Wang, P. Filippakopoulos · 2015 · Trends in Biochemical Sciences
57. Kin28 regulates the transient association of Mediator with core promoters
    Celia Jerónimo, François Robert · 2014 · Nature Structural & Molecular Biology
58. Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity
    Wen Fong Ooi, Manjie Xing, Chang Xu, Xiaosai Yao, Muhammad Khairul Ramlee, Mei Chee Lim, Fan Cao, Kevin Junliang Lim, Deepak Babu, Lai-Fong Poon et al. · 2016 · Nature Communications
59. Genome-wide analyses reveal a role of Polycomb in promoting hypomethylation of DNA methylation valleys
    Yuanyuan Li, Hui Zheng, Qiujun Wang, Chen Zhou, Lei Wei, Xuehui Liu, Wenhao Zhang, Yu Zhang, Zhenhai Du, Xiaowo Wang et al. · 2018 · Genome biology
60. PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program
    Matthew Harms, Hee‐Woong Lim, Yugong Ho, Suzanne N. Shapira, Jeff Ishibashi, Sona Rajakumari, David J. Steger, Mitchell A. Lazar, Kyoung‐Jae Won, Patrick Seale · 2015 · Genes & Development
61. TGF-β Family Signaling in Embryonic and Somatic Stem-Cell Renewal and Differentiation
    Alan C. Mullen, Jeffrey L. Wrana · 2017 · Cold Spring Harbor Perspectives in Biology
62. MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state
    Vittoria Poli, Luca Fagnocchi, Alessandra Fasciani, Alessandro Cherubini, Stefania Mazzoleni, Sara Ferrillo, Annarita Miluzio, Gabriella Gaudioso, Valentina Vaira, Alice Turdo et al. · 2018 · Nature Communications
63. Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies
    Andrew P. Morris, Thu H Le, Hao Wu, Artur Akbarov, Peter J. van der Most, Gibran Hemani, George Davey Smith, Anubha Mahajan, Kyle J. Gaulton, Girish N. Nadkarni et al. · 2018 · Nature Communications
64. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes
    Shilpa S. Dhar, Dongyu Zhao, Tao Lin, Bingnan Gu, Khusboo Pal, Sarah J. Wu, Hunain Alam, Jie Lv, Kyuson Yun, Vidya Gopalakrishnan et al. · 2018 · Molecular Cell
65. Cdk7: a kinase at the core of transcription and in the crosshairs of cancer drug discovery
    Robert P. Fisher · 2018 · Transcription
66. Fine-Tuning Cytokine Signals
    Jian‐Xin Lin, Warren J. Leonard · 2019 · Annual Review of Immunology
67. Hemoglobin switching’s surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin.
    Bauer, Daniel E, Orkin, Stuart H · 2015 · Current Opinion in Genetics & Development
68. Editing the Epigenome: Reshaping the Genomic Landscape
    Liad Holtzman, Charles A. Gersbach · 2018 · Annual Review of Genomics and Human Genetics
69. Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo
    Ruth M. Williams, Ivan Candido-Ferreira, Emmanouela Repapi, Daria Gavriouchkina, Upeka Senanayake, Irving T. C. Ling, Jelena M. Telenius, Stephen Taylor, Jim R. Hughes, Tatjana Sauka‐Spengler · 2019 · Developmental Cell
70. Super enhancers define regulatory subtypes and cell identity in neuroblastoma
    Moritz Gartlgruber, Ashwini Kumar Sharma, Andrés Quintero, Daniel Dreidax, Selina Jansky, Young-Gyu Park, Sina Kreth, Johanna Meder, Daria Doncevic, Paul Saary et al. · 2020 · Nature Cancer
71. Genome-Wide Profiles of Extra-cranial Malignant Rhabdoid Tumors Reveal Heterogeneity and Dysregulated Developmental Pathways
    Hye-Jung E. Chun, Emilia L. Lim, Alireza Heravi‐Moussavi, Saeed Saberi, Karen Mungall, Mikhail Bilenky, Annaïck Carles, Kane Tse, Inna Shlafman, Kelsey Zhu et al. · 2016 · Cancer Cell
72. Super-enhancer function and its application in cancer targeted therapy
    Faqing Tang, Zongbei Yang, Yuan Tan, Yuejin Li · 2020 · npj Precision Oncology
73. The role of histone methylation in the development of digestive cancers: a potential direction for cancer management
    Yuan Chen, Bo Ren, Jinshou Yang, Huanyu Wang, Gang Yang, Ruiyuan Xu, Lei You, Yupei Zhao · 2020 · Signal Transduction and Targeted Therapy
74. Stem Cells, Genome Editing, and the Path to Translational Medicine
    Frank Soldner, Rudolf Jaenisch · 2018 · Cell
75. The MYC Enhancer-ome: Long-Range Transcriptional Regulation of MYC in Cancer
    Olga Lancho, Daniel Herranz · 2018 · Trends in cancer
76. Building Robust Transcriptomes with Master Splicing Factors
    Jangi, Mohini, Sharp, Phillip A. · 2014 · Cell
77. BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer
    Yuhki Yokoyama, Hengrui Zhu, Jeong‐Heon Lee, Andrew V. Kossenkov, Sherry Y. Wu, Jayamanna M. Wickramasinghe, Xiangfan Yin, Katherine C. Palozola, Alessandro Gardini, Louise C. Showe et al. · 2016 · Cancer Research
78. DNA methylation at enhancers identifies distinct breast cancer lineages
    Thomas Fleischer, Xavier Tekpli, Anthony Mathelier, Shixiong Wang, Daniel J. H. Nebdal, Hari Prasad Dhakal, Kristine Kleivi Sahlberg, Ellen Schlichting, Torill Sauer, Jürgen Geisler et al. · 2017 · Nature Communications
79. Super-Enhancer–Associated Long Noncoding RNA HCCL5 Is Activated by ZEB1 and Promotes the Malignancy of Hepatocellular Carcinoma
    Li Peng, Binyuan Jiang, Xiaoqing Yuan, Yuntan Qiu, Jiangyun Peng, Yongsheng Huang, Chaoyang Zhang, Yin Zhang, Zhaoyu Lin, Jinsong Li et al. · 2018 · Cancer Research
80. Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures
    Vivek Rai, Daniel X. Quang, Michael R. Erdos, Darren A. Cusanovich, Riza M. Daza, Narisu Narisu, Luli S. Zou, John P. Didion, Yuanfang Guan, Jay Shendure et al. · 2019 · Molecular Metabolism
81. Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness
    Haiquan Lu, Yangyiran Xie, Thi My Linh Tran, Jie Lan, Yongkang Yang, Naveena L. Murugan, Ru Wang, Yueyang J. Wang, Gregg L. Semenza · 2020 · Journal of Clinical Investigation
82. Epigenetic Changes in Diabetes and Cardiovascular Risk
    Keating, Samuel T., Plutzky, Jorge, El-Osta, Assam · 2016 · Circulation Research
83. High-Resolution Epigenomic Atlas of Human Embryonic Craniofacial Development
    Wilderman, Andrea, VanOudenhove, Jennifer, Kron, Jeffrey, Noonan, James P., Cotney, Justin · 2018 · Cell Reports
84. The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis
    Xiao‐Jian Sun, Na Man, Yurong Tan, Stephen D. Nimer, Lan Wang · 2015 · Frontiers in Oncology
85. Tregopathies: Monogenic diseases resulting in regulatory T-cell deficiency
    Alma‐Martina Cepika, Yohei Sato, Jeffrey Mao-Hwa Liu, Molly Javier Uyeda, Rosa Bacchetta, Maria Grazia Roncarolo · 2018 · Journal of Allergy and Clinical Immunology
86. BiRen: predicting enhancers with a deep-learning-based model using the DNA sequence alone
    Bite Yang, Feng Liu, Chao Ren, Zhangyi Ouyang, Ziwei Xie, Xiaochen Bo, Wenjie Shu · 2017 · Bioinformatics
87. Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation
    Ka Lung Cheung, Fan Zhang, Anbalagan Jaganathan, Rajal Sharma, Qiang Zhang, Tsuyoshi Konuma, Tong Shen, June‐Yong Lee, Chunyan Ren, Chih‐Hung Chen et al. · 2017 · Molecular Cell
88. Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling
    Hao Huang, Jianyang Hu, Alishba Maryam, Qinghua Huang, Yuchen Zhang, Saravanan Ramakrishnan, Jingyu Li, Haiying Ma, W. Victor, Wah Cheuk et al. · 2021 · Nature Communications
89. The essential and multifunctional TFIIH complex
    Jenna K. Rimel, Dylan J. Taatjes · 2018 · Protein Science
90. Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance
    Mingjun Bi, Zhao Zhang, Yi‐Zhou Jiang, Pengya Xue, Hu Wang, Zhao Lai, Xiaoyong Fu, Carmine De Angelis, Yue Gong, Zhen Gao et al. · 2020 · Nature Cell Biology
91. Control of Immune Cell Homeostasis and Function by lncRNAs
    Walter K. Mowel, Jonathan J. Kotzin, Sam J. McCright, Vanessa D. Neal, Jorge Henao‐Mejia · 2017 · Trends in Immunology
92. The developmental origin of brain tumours: a cellular and molecular framework
    Roberta Azzarelli, Benjamin D. Simons, Anna Philpott · 2018 · Development
93. Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma
    Jiaqiang Dong, Jiong Li, Yang Li, Zhikun Ma, Yongxin Yu, Cun‐Yu Wang · 2021 · Nature Communications
94. circRNA Hipk3 Induces Cardiac Regeneration after Myocardial Infarction in Mice by Binding to Notch1 and miR-133a
    Xiaoyun Si, Hao Zheng, Guoquan Wei, Mengsha Li, Wei Li, Houmei Wang, Haijun Guo, Jie Sun, Chuling Li, Shenrong Zhong et al. · 2020 · Molecular Therapy — Nucleic Acids
95. Long-range enhancers regulating Myc expression are required for normal facial morphogenesis
    Veli Vural Uslu, M. Petretich, Sandra Ruf, Katja Langenfeld, Nuno A. Fonseca, John C. Marioni, François Spitz · 2014 · Nature Genetics
96. Epigenetic Regulation of NAMPT by NAMPT-AS Drives Metastatic Progression in Triple-Negative Breast Cancer
    Hanwen Zhang, Ning Zhang, Ying Liu, Peng Su, Yiran Liang, Yaming Li, Xiaolong Wang, Tong Chen, Xiaojin Song, Yuting Sang et al. · 2019 · Cancer Research
97. Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors
    Yang, Yaxi, Zhang, Rukang, Li, Zhaojun, Mei, Lianghe, Wan, Shili, Ding, Hong, Chen, Zhifeng, Xing, Jing, Feng, Huijin, Han, Jie et al. · 2020 · Journal of Medicinal Chemistry
98. Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist
    Michael R. McKeown, M. Ryan Corces, Matthew L. Eaton, Chris Fiore, Emily Lee, Jeremy T. Lopez, Mei Wei Chen, Darren Smith, Steven M. Chan, Julie L. Koenig et al. · 2017 · Cancer Discovery
99. Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems
    Nancy V. N. Carullo, Robert A Phillips III, Rhiana C. Simon, Salomon A Roman Soto, Jenna E. Hinds, Aaron J. Salisbury, Jasmin S. Revanna, Kendra D. Bunner, Lara Ianov, Faraz A. Sultan et al. · 2020 · Nucleic Acids Research
100. Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes
     Steven M. Blinka, Michael H. Reimer, Kirthi Pulakanti, Sridhar Rao · 2016 · Cell Reports