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Mechanisms and Functions of Inflammasomes
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Citations
Cites
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A role for mitochondria in nlrp3 inflammasome activation
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Non-canonical inflammasome activation targets caspase-11
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Self-citationThe NALP3 inflammasome is involved in the innate immune response to amyloid-β
Halle, A., Hornung, V., Petzold, G. C., Stewart, C. R., Monks, B. G., Reinheckel, T., Fitzgerald, K. A., Latz, E., Moore, K. J., & Golenbock, D. T. (2008) · Nature Immunology · doi:10.1038/ni.1636 · Cited by 2,441
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
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“, 2013) have important roles in the Nlrp3 pathway (Ermler et al., 2014; He et al., 2013; Masters et al., 2010; Muñoz-Planillo et al., 2013).”
BackgroundInfluentialFranchi, L., Amer, A., Body-Malapel, M., Kanneganti, T.-D., Özören, N., Jagirdar, R., Inohara, N., Vandenabeele, P., Bertin, J., Coyle, A., et al. (2006) · Nature Immunology · doi:10.1038/ni1346 · Cited by 1,131
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
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“…components of pathogenic bacteria: flagellin, the building block of their locomotion machinery, and proteins from the type III and IV bacterial secretion systems that inject virulence factors into the host cell (Amer et al., 2006; Franchi et al., 2006; Miao et al., 2006; Miao et al., 2010b).”
BackgroundThe apoptosome: Signalling platform of cell death
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“Interaction motifs belonging to the ''death domain'' superfamily bring the zymogens into the activating protein complex (Lamkanfi and Dixit, 2012; Riedl and Salvesen, 2007).”
BackgroundInfluentialSelf-citationDICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
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Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
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Self-citationRegulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf
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Cited by
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Shi, J., Zhao, Y., Wang, K., Shi, X., Wang, Y., Huang, H., Zhuang, Y., Cai, T., Wang, F., & Shao, F. (2015) · Nature · doi:10.1038/nature15514 · Cited by 6,659
The NLRP3 Inflammasome: an overview of mechanisms of activation and regulation
Kelley, N., Jeltema, D., Duan, Y., & He, Y. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133328 · Cited by 3,539
Inflammasomes: mechanism of action, role in disease, and therapeutics
Guo, H., Callaway, J. B., & Ting, J. P.-Y. (2015) · Nature Medicine · doi:10.1038/nm.3893 · Cited by 3,340
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Liu, X., Zhang, Z., Ruan, J., Pan, Y., Magupalli, V. G., Wu, H., & Lieberman, J. (2016) · Nature · doi:10.1038/nature18629 · Cited by 3,202
Periodontitis: from microbial immune subversion to systemic inflammation
Hajishengallis, G. (2015) · Nature Reviews Immunology · doi:10.1038/nri3785 · Cited by 3,046
Metadata
- Authors
- Lamkanfi, M., & Dixit, V. M.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2014-05
- Volume
- 157
- Issue
- 5
- Pages
- 1013-1022
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2089503694
- Cited by
- 2,503
- References
- 23
- FWCI
- 63.64
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
