Hippo pathway in organ size control, tissue homeostasis, and cancer

Yu, Fa-Xing, Zhao, Bin, Guan, Kun-Liang·2015·Cell

DOI 10.1016/j.cell.2015.10.044

Cited by (1,005)

Items 801–900 of 1,005

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Benjamin D. Wasinski, Anjum Sohail, R. Daniel Bonfil, Seongho Kim, Allen D. Saliganan, Lisa Polin, Mohamad Bouhamdan, Hyeong-Reh Choi Kim, Marco Prunotto, Rafael A. Fridman · 2020 · Scientific Reports
Regulation and functions of the Hippo pathway in stemness and differentiation
Xiaolei Cao, Chenliang Wang, Jiyang Liu, Bin Zhao · 2020 · Acta Biochimica et Biophysica Sinica
RETRACTED ARTICLE: Interplay between cancer cells and M2 macrophages is necessary for miR-550a-3-5p down-regulation-mediated HPV-positive OSCC progression
Ming‐xin Cao, Wei‐long Zhang, Xianghua Yu, Jia‐shun Wu, Xinwei Qiao, Mei-chang Huang, Ke Wang, Jing‐biao Wu, Ya-Jie Tang, Jian Dong Jiang et al. · 2020 · Journal of Experimental & Clinical Cancer Research · Retracted
YAP/TAZ Regulate Elevation and Bone Formation of the Mouse Secondary Palate
Alice F. Goodwin, Christopher P. Chen, Nu Vo, Jeffrey Ohmann Bush, Ophir D. Klein · 2020 · Journal of Dental Research
Hypoxia Protects Rat Bone Marrow Mesenchymal Stem Cells Against Compression-Induced Apoptosis in the Degenerative Disc Microenvironment Through Activation of the HIF-1α/YAP Signaling Pathway
Zhe Wang, Min Cui, Yanji Qu, Ruijun He, Wei Wu, Hui Lin, Zengwu Shao · 2020 · Stem Cells and Development
YAP1-FAM118B Fusion Defines a Rare Subset of Childhood and Young Adulthood Meningiomas
Kathleen M. Schieffer, Vibhuti Agarwal, Stephanie LaHaye, Katherine E. Miller, Daniel C. Koboldt, Tara M. Lichtenberg, Kristen Leraas, Patrick Joseph Brennan, Benjamin Kelly, Erin R. Crist et al. · 2020 · The American Journal of Surgical Pathology
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YAP inactivation in estrogen receptor alpha-positive hepatocellular carcinoma with less aggressive behavior
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The Hippo signaling pathway in leukemia: function, interaction, and carcinogenesis
Negar Noorbakhsh, Bentolhoda Hayatmoghadam, Marzieh Jamali, Maryam Golmohammadi, Maria Kavianpour · 2021 · Cancer Cell International
PI3K/Akt/YAP signaling promotes migration and invasion of DLD‑1 colorectal cancer cells
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The roles of E3 ligases in Hepatocellular carcinoma.
Zongdong Yu, Hong Li, Jie Zhu, Haibiao Wang, Xiaofeng Jin · 2022 · PubMed Central
Hippo (YAP)–autophagy axis protects against hepatic ischemia-reperfusion injury through JNK signaling
Shuguang Zhu, Xiaowen Wang, Haoqi Chen, Wenfeng Zhu, Xuejiao Li, Ruiwen Cui, Xiaomeng Yi, Xiaolong Chen, Hua Li, Genshu Wang · 2023 · Chinese Medical Journal
β‐Adrenoceptor activation affects galectin‐3 as a biomarker and therapeutic target in heart disease
Xiao‐Jun Du, Weibo Zhao, My‐Nhan Nguyen, Qun Lu, Helen Kiriazis · 2019 · British Journal of Pharmacology
Resveratrol ameliorates lipopolysaccharide-induced anxiety-like behavior by attenuating YAP-mediated neuro-inflammation and promoting hippocampal autophagy in mice
Qiuyun Tian, Xiaofang Fan, Jianshe Ma, Yujiao Han, Dantong Li, Shan Jiang, Fukun Zhang, Hui Guang, Xiaoqiong Shan, Ran Chen et al. · 2020 · Toxicology and Applied Pharmacology
Polycystic kidney disease: a Hippo connection
Shenghong Ma, Kun‐Liang Guan · 2018 · Genes & Development
HSP90β chaperoning SMURF1-mediated LATS proteasomal degradation in the regulation of bone formation
Meiyu Qu, Ying Gong, Yuyang Jin, Ruibo Gao, Qiangqiang He, Yana Xu, Tingyu Shen, Liu Mei, Chengyun Xu, Musaddique Hussain et al. · 2022 · Cellular Signalling
Single-cell dynamics of liver development in postnatal pigs
Lin Rao, Liping Cai, Lusheng Huang · 2023 · 中国科学通报：英文版
Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation
Tomoaki Nagai, Kensaku Mizuno · 2017 · PLoS ONE
Inhibition of Lats1/p‐ YAP 1 pathway mitigates neuronal apoptosis and neurological deficits in a rat model of traumatic brain injury
Di Li, Jiaxuan Ji, Yitian Xu, Haibo Ni, Qin Rui, Huixiang Liu, Feng Jiang, Rong Gao, Gang Chen · 2018 · CNS Neuroscience & Therapeutics
Reduced SERCA Function Preferentially Affects Wnt Signaling by Retaining E-Cadherin in the Endoplasmic Reticulum
Annabelle Suisse, Jessica E. Treisman · 2019 · Cell Reports
Inhibition of Siah2 ubiquitin ligase ameliorates monocrotaline-induced pulmonary arterial remodeling through inactivation of YAP
Qingting Wang, Wenhua Shi, Qianqian Zhang, Wei Feng, Jian Wang, Cui Zhai, Xin Yan, Manxiang Li · 2019 · Life Sciences
The Snakeskin-Mesh Complex of Smooth Septate Junction Restricts Yorkie to Regulate Intestinal Homeostasis in Drosophila
Hsi‐Ju Chen, Qi Li, Niraj K. Nirala, Yicktung Tony Ip · 2020 · Stem Cell Reports
Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells
Nicholas Van Sciver, Makoto Ohashi, Nicholas P. Pauly, Jillian A. Bristol, Scott E. Nelson, Eric Johannsen, Shannon C. Kenney · 2021 · PLoS Pathogens
Yap Regulates Müller Glia Reprogramming in Damaged Zebrafish Retinas
Raquel Lourenço, Ana S. Brandão, Jorge Borbinha, Rita Gorgulho, António Jacinto · 2021 · Frontiers in Cell and Developmental Biology
Retracted: Lovastatin Inhibits RhoA to Suppress Canonical Wnt/β-Catenin Signaling and Alternative Wnt-YAP/TAZ Signaling in Colon Cancer
Yi Xiao, Qin Liu, Nanyin Peng, Yuzhang Li, Danyang Qiu, Tianlun Yang, Richard D. Kang, Ahsan Usmani, Efosa Amadasu, Cesar V. Borlongan et al. · 2022 · Cell Transplantation · Retracted
HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity
Bo Yuan, Jinquan Liu, Aiping Shi, Jin Cao, Yi Yu, Yezhang Zhu, Chengbin Zhang, Yifei Qiu, Hongjie Luo, Jiaxian Shi et al. · 2023 · The EMBO Journal
Pleiotropic Roles of a KEAP1-Associated Deubiquitinase, OTUD1
Daisuke Oikawa, Kouhei Shimizu, Fuminori Tokunaga · 2023 · Antioxidants
Targeting high Aurora kinases expression as an innovative therapy for hepatocellular carcinoma
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The Hippo Pathway Maintains the Equatorial Division Plane in the CiliateTetrahymena
Yu‐Yang Jiang, Wolfgang Maier, Ralf Baumeister, Gregory Minevich, Ewa Joachimiak, Zheng Ruan, Natarajan Kannan, Diamond Clarke, Joseph Frankel, Jacek Gaertig · 2017 · Genetics
E-Cadherin–Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis
Guojiang Xie, Xiulan Ao, Tianmiao Lin, Guixuan Zhou, Ming Wang, Han-Wei Wang, Yuangui Chen, Xiaobo Li, Benhua Xu, Wangzhong He et al. · 2017 · Journal of Investigative Dermatology
AMOT is required for YAP function in high glucose induced liver malignancy
Ya Liu, Zhicheng Lu, Yi Shi, Fenyong Sun · 2017 · Biochemical and Biophysical Research Communications
Ubiquitin-Dependent Regulation of the Mammalian Hippo Pathway: Therapeutic Implications for Cancer
Thanh Nguyen, Jan‐Michael Kugler · 2018 · Cancers
Standard CD44 modulates YAP1 through a positive feedback loop in hepatocellular carcinoma
Zhenhai Fan, Hongwei Xia, Huanji Xu, Ji Ma, Sheng Zhou, Wanting Hou, Qiulin Tang, Qiyong Gong, Yongzhan Nie, Feng Bi · 2018 · Biomedicine & Pharmacotherapy
Gelsolin-like actin-capping protein has prognostic value and promotes tumorigenesis and epithelial-mesenchymal transition via the Hippo signaling pathway in human bladder cancer
Zhaojie Lyu, Yuchen Liu, Miao Chen, Chen Yacun, Shayi Wu, Anbang He, Liao Xinhui, Meng Zhang, Peipei Wu, Hongbing Mei et al. · 2019 · Therapeutic Advances in Medical Oncology
The molecular rationale for therapeutic targeting of glutamine metabolism in pulmonary hypertension
Thomas Bertero, Dror Perk, Stephen Y. Chan · 2019 · Expert Opinion on Therapeutic Targets
A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation
Yangqing Shao, Xin Shu, Yi Lu, Wenxuan Zhu, Ran Li, Huanyi Fu, Chengyu Li, Wei Sun, Zhuo Li, Yitong Zhang et al. · 2024 · Nature Cell Biology
YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate
M. D. Pankratova, Andrei A. Riabinin, Elizaveta A. Butova, Arseniy V. Selivanovskiy, Elena I. Morgun, Sergey V. Ulianov, Ekaterina Andreevna Vorotelyak, Ekaterina P. Kalabusheva · 2024 · International Journal of Molecular Sciences
CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly
Salil Kalarikkal Sukumaran, Maria Stumpf, Sarah Salamon, Ilyas Ahmad, Kurchi Bhattacharya, Sarah Fischer, Rolf Müller, Janine Altmüller, Birgit Susanne Budde, Holger Thiele et al. · 2016 · Molecular Genetics and Genomics
MST kinases in innate immune signaling
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YAP Activity is Not Associated with Survival of Uveal Melanoma Patients and Cell Lines
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Astrocytic Yes-associated protein attenuates cerebral ischemia-induced brain injury by regulating signal transducer and activator of transcription 3 signaling
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Oxidative Stress-Mediated YAP Dysregulation Contributes to the Pathogenesis of Pemphigus Vulgaris
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Chu‐Yen Chien, Ying-Chen Chen, Chia‐Chen Hsu, Yu‐Ting Chou, Shine‐Gwo Shiah, Shyun-Yeu Liu, Alexander Cheng-Ting Hsieh, Ching‐Yu Yen, Chien-Hsing Lee, Yi‐Shing Shieh · 2021 · Cells
Apoptosis in Type 2 Diabetes: Can It Be Prevented? Hippo Pathway Prospects
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Lin Wang, Qinghua Jiang, Siyu Chen, Siyi Wang, Jingyi Lu, Xun Gao, Dongfang Zhang, Xin Jin · 2023 · Bioorganic Chemistry
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NTRK1 is a positive regulator of YAP oncogenic function
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Hippo pathway activation mediates cardiomyocyte ferroptosis to promote dilated cardiomyopathy through downregulating NFS1
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Immunohistochemistry for NF2, LATS1/2, and YAP/TAZ Fails to Separate Benign From Malignant Mesothelial Proliferations
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Reprogramming of ovarian granulosa cells by YAP1 leads to development of high-grade cancer with mesenchymal lineage and serous features
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YAP promotes endothelial barrier repair by repressing STAT3/VEGF signaling
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A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling
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A Framework of Major Tumor-Promoting Signal Transduction Pathways Implicated in Melanoma-Fibroblast Dialogue
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Oncogenic Hedgehog-Smoothened Signaling Depends on YAP1‒TAZ/TEAD Transcription to Restrain Differentiation in Basal Cell Carcinoma
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Feeling the right force: How to contextualize the cell mechanical behavior in physiologic turnover and pathologic evolution of the cardiovascular system
Maurizio Pesce, Rosaria Santoro · 2016 · Pharmacology & Therapeutics
Integrin‐FAK‐CDC42‐PP1A signaling gnaws at YAP/TAZ activity to control incisor stem cells
Julia Hicks‐Berthet, Xaralabos Varelas · 2017 · BioEssays
Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence
Chiharu Miyajima, Yuki Kawarada, Yasumichi Inoue, Chiaki Suzuki, Kana Mitamura, Daisuke Morishita, Nobumichi Ohoka, Takeshi Imamura, Hidetoshi Hayashi · 2020 · Cells
Epstein–Barr Virus in Inborn Immunodeficiency—More Than Infection
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Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges
Aviral Kumar, Bandari BharathwajChetty, Mukesh Kumar Manickasamy, Jyothsna Unnikrishnan, Mohammed Saeed Alqahtani, Muhammad Abbas, Hassan Ali Almubarak, Gautam Sethi, Ajaikumar Bahulayan Kunnumakkara · 2024 · Pharmacological Research
Hippo Signaling Pathway in Colorectal Cancer: Modulation by Various Signals and Therapeutic Potential
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Proteomic Profiling of Stem Cell Tissues during Regeneration of Deer Antler: A Model of Mammalian Organ Regeneration
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The crosstalk between AXL and YAP promotes tumor progression through STAT3 activation in head and neck squamous cell carcinoma
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SHANK2 is a frequently amplified oncogene with evolutionarily conserved roles in regulating Hippo signaling
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Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells
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Neural peptide promotes the angiogenesis and osteogenesis around oral implants
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