Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
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Items 301–400 of 1,005
- Pulmonary Stretch and Lung Mechanotransduction: Implications for Progression in the Fibrotic LungAlessandro Marchioni, Roberto Tonelli, Stefania Cerri, Ivana Castaniere, Dario Andrisani, Filippo Gozzi, Giulia Bruzzi, Linda Manicardi, Antonio Moretti, Jacopo Demurtas et al. · 2021 · International Journal of Molecular Sciences
- Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2Fang-Ling Zhang, Xiaowei Chen, Yi-Fan Wang, Zhen Hu, Wenjuan Zhang, Bowei Zhou, Peng-Fei Ci, Ke‐Xuan Liu · 2023 · Journal of Translational Medicine
- Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusionKe-Xun Yu, Wei-Jie Yuan, Hui-Zhen Wang, Yongxiang Li · 2024 · Cancer Immunology Immunotherapy
- Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAPDawei Zhang, Shanzheng Yang, Enrique M. Toledo, Daniel Gyllborg, Carmen Saltó, J. Carlos Villaescusa, Ernest Arenas · 2017 · Science Signaling
- TRIP6 inhibits Hippo signaling in response to tension at adherens junctionsShubham Dutta, Sebastian Mana‐Capelli, Murugan Paramasivam, Ishani Dasgupta, Heather A. Cirka, Kris Billiar, Dannel McCollum · 2017 · EMBO Reports
- YAP1‐LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasisChunbo He, Xiangmin Lv, Cong Huang, Guohua Hua, Bowen Ma, Xingcheng Chen, Peter C. Angeletti, Jixin Dong, Jin Rong Zhou, Zhengfeng Wang et al. · 2019 · EMBO Reports
- Recent Advances of the Hippo/YAP Signaling Pathway in Brain Development and GliomaTaohui Ouyang, Wei Meng, Meihua Li, Tao Hong, Na Zhang · 2019 · Cellular and Molecular Neurobiology
- Regulation of cardiomyocyte fate plasticity: a key strategy for cardiac regenerationRui Gong, Zuke Jiang, Naufal Sh. Zagidullin, Tianyi Liu, Benzhi Cai · 2021 · Signal Transduction and Targeted Therapy
- Mechanical stretch induces osteogenesis through the alternative activation of macrophagesLili Dong, Yang Song, Yajie Zhang, Weikang Zhao, Chunli Wang, Hungchun Lin, Mohanad Kh Al-ani, Wanqian Liu, Ruyue Xue, Li Yang · 2021 · Journal of Cellular Physiology
- SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signalingChuan Shan Xu, Guoxiang Jin, Hong Wu, Wei Cui, Yu-Hui Wang, Rajesh Kumar Manne, Guihua Wang, Weina Zhang, Xian Zhang, Fei Han et al. · 2022 · Journal of Clinical Investigation
- The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targetingNicolas Jonckheere, Romain Vasseur, Isabelle VAN SEUNINGEN · 2017 · Critical Reviews in Oncology/Hematology
- The role of FOXG1 in the postnatal development and survival of mouse cochlear hair cellsZuhong He, Qiaojun Fang, He Li, Buwei Shao, Yuan Zhang, Yuhua Zhang, Xiao Han, Rongrong Guo, Cheng Cheng, Lingna Guo et al. · 2018 · Neuropharmacology
- RETRACTED ARTICLE: Metformin-repressed miR-381-YAP-snail axis activity disrupts NSCLC growth and metastasisDan Jin, Jiwei Guo, Yan Wu, Weiwei Chen, Jing Du, Lijuan Yang, Xiaohong Wang, Kaikai Gong, Juanjuan Dai, Shuang Miao et al. · 2020 · Journal of Experimental & Clinical Cancer Research · Retracted
- Atherosclerosis: Insights into Vascular Pathobiology and Outlook to Novel TreatmentsMarc Wolf, Patrick Hunziker · 2020 · Journal of Cardiovascular Translational Research
- The role of Hippo‐YAP signaling in squamous cell carcinomasTomohiko Maehama, Miki Nishio, Junji Otani, Tak W. Mak, Akira Suzuki · 2020 · Cancer Science
- A genetic mammalian proportional–integral feedback control circuit for robust and precise gene regulationTimothy Frei, Ching-Hsiang Chang, Maurice Filo, Asterios Arampatzis, Mustafa Khammash · 2022 · Proceedings of the National Academy of Sciences
- PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling PathwaysYulei Zhao, Tess Montminy, Taha Azad, Elizabeth D. Lightbody, Yawei Hao, Sandip Sengupta, Éric Asselin, Christopher J.B. Nicol, Xiaolong Yang · 2018 · Molecular Cancer Research
- Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy2019 · Advances in Cancer Research
- YAP repression of the WNT3 gene controls hESC differentiation along the cardiac mesoderm lineageConchi Estarás, Hui-Ting Hsu, Ling Huang, Katherine A. Jones · 2017 · Genes & Development
- Dual inhibition of Wnt and Yes‐associated protein signaling retards the growth of triple‐negative breast cancer in both mesenchymal and epithelial statesAndrew Sulaiman, Sarah McGarry, Li Li, Deyong Jia, Sarah Ooi, Christina Addison, Jim Dimitroulakos, Angel Arnaout, Carolyn Nessim, Zemin Yao et al. · 2018 · Molecular Oncology
- The MST4–MOB4 complex disrupts the MST1–MOB1 complex in the Hippo–YAP pathway and plays a pro-oncogenic role in pancreatic cancerChen, Min, Zhang, Hui, Shi, Zhubing, Li, Yehua, Zhang, Xiaoman, Gao, Ziyang, Zhou, Li, Ma, Jian, Xu, Qi, Guan, Jingmin et al. · 2018 · Journal of Biological Chemistry
- The Roles of Hippo Signaling Transducers Yap and Taz in Chromatin RemodelingRyan E. Hillmer, Brian A. Link · 2019 · Cells
- Effect of the acylation of TEAD4 on its interaction with co‐activators YAP and TAZYannick Mesrouze, Marco Meyerhofer, Fedir M. Bokhovchuk, Patrizia Fontana, Catherine Zimmermann, Typhaine Martin, Clara Delaunay, Aude Izaac, Joerg A. Kallen, Tobias Schmelzle et al. · 2017 · Protein Science
- MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathwayLi Li, Jianguo Zhao, Shanshan Huang, Yi Wang, Lingling Zhu, Yuan Cao, Jianping Xiong, Jun Deng · 2017 · Gene
- Proliferation of hepatic stellate cells, mediated by YAP and TAZ, contributes to liver repair and regeneration after liver ischemia-reperfusion injuryTakanori Konishi, Rebecca M. Schuster, Alex B. Lentsch · 2018 · American Journal of Physiology-Gastrointestinal and Liver Physiology
- Loss of VGLL4 suppresses tumor PD‐L1 expression and immune evasionAiling Wu, Qingzhe Wu, Yujie Deng, Yuning Liu, Jinqiu Lu, Liansheng Liu, Xiaoling Li, Cheng Lin Liao, Bin Zhao, Hai Xin Song · 2018 · The EMBO Journal
- Hepatic Hippo signaling inhibits development of hepatocellular carcinomaYuchen Liu, Xiaohui Wang, Yingzi Yang · 2020 · Clinical and Molecular Hepatology
- Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription FactorSeiichiro Mori, Takamasa Takeuchi, Yoshiyuki Ishii, Takashi Yugawa, Tohru Kiyono, Hiroshi Nishina, Iwao Kukimoto · 2017 · Journal of Virology
- Role of cytoplasmic lncRNAs in regulating cancer signaling pathwaysPeifen Fu, Xin Min Zheng, Fan Xiao, Aifu Lin · 2019 · Journal of Zhejiang University SCIENCE B
- LINC01559 accelerates pancreatic cancer cell proliferation and migration through YAP‐mediated pathwayChangjie Lou, Juan Zhao, Yuanlong Gu, Qingwei Li, Shuli Tang, Yangjiazi Wu, Jiebing Tang, Chunhui Zhang, Zhiwei Li, Yanqiao Zhang · 2019 · Journal of Cellular Physiology
- YAP–TEAD1 control of cytoskeleton dynamics and intracellular tension guides human pluripotent stem cell mesoderm specificationStefania Pagliari, Vladimír Vinarský, Fabiana De Martino, Ana Rubina Perestrelo, Jorge Oliver‐De La Cruz, Guido Caluori, Jan Vrbský, Pamela Mozetic, Antonio Pompeiano, Andrea Zancla et al. · 2020 · Cell Death and Differentiation
- EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1Toshinori Ando, Nadia Arang, Zhiyong Wang, Daniela Elena Costea, Xiaodong Feng, Yusuke Goto, Hiroki Izumi, Mara Gilardi, Kazuyo Ando, Jorge Silvio Gutkind · 2021 · Communications Biology
- Targeting signaling pathways in osteosarcoma: Mechanisms and clinical studiesZiyu Ji, Jianlin Shen, Yujian Lan, Qian Yi, Huan Liu · 2023 · MedComm
- A critical role for NF2 and the Hippo pathway in branching morphogenesisAntoine Reginensi, Leonie Enderle, Alex Gregorieff, Randy L. Johnson, Jeffrey L. Wrana, Helen McNeill · 2016 · Nature Communications
- Expression and significance of Hippo/YAP signaling in glioma progressionHao Zhang, Decheng Geng, Jian Gao, Yanhua Qi, Yi Shi, Yan Wang, Yang Jiang, Yu Zhang, Jiale Fu, Yu Juan Dong et al. · 2016 · Tumor Biology
- DNA-binding mechanism of the Hippo pathway transcription factor TEAD4Zhubing Shi, F He, Mei Chen, Lei Hua, Wenshuai Wang, Shi Jiao, Zhaocai Zhou · 2017 · Oncogene
- Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactionsZhengdong Jiang, Cancan Zhou, Liang Cheng, Bin Yan, Ke Chen, Xin Chen, Liang Zong, Jianjun Lei, Wanxing Duan, Qinhong Xu et al. · 2018 · Journal of Experimental & Clinical Cancer Research
- Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZZhijun Liu, Yiju Wei, Lei Zhang, Patricia P. Yee, Martin Johnson, Xuexin Zhang, Melissa Gulley, Jennifer M. Atkinson, Mohamed Trebak, Hong‐Gang Wang et al. · 2018 · Oncogene
- Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancerHui-Yi Wang, Qiaoyun Long, Shan‐Bo Tang, Qiong Xiao, Chuan Gao, Quanyi Zhao, Qinglan Li, Mei Ye, Lei Zhang, Lianyun Li et al. · 2019 · Nucleic Acids Research
- YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing NeocortexMilos Kostic, Judith T.M.L. Paridaen, Katherine R. Long, Nereo Kalebic, Barbara Langen, Nannette Grübling, Pauline Wimberger, Hiroshi Kawasaki, Takashi Namba, Wieland Β. Huttner · 2019 · Cell Reports
- MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathwayLiwei An, Pingping Nie, Min Chen, Yang Tang, Hui Zhang, Jingmin Guan, Zhifa Cao, Chun Hou, Wenjia Wang, Yun Zhao et al. · 2020 · The Journal of Experimental Medicine
- Critical roles of phosphoinositides and NF2 in Hippo pathway regulationAudrey W. Hong, Zhipeng Meng, Steven W. Plouffe, Zhijie Lin, Mingjie Zhang, Kun‐Liang Guan · 2020 · Genes & Development
- Covalent disruptor of YAP-TEAD association suppresses defective Hippo signalingFan, Mengyang, Lu, Wenchao, Che, Jianwei, Kwiatkowski, Nicholas P, Gao, Yang, Seo, Hyuk-Soo, Ficarro, Scott B, Gokhale, Prafulla C, Liu, Yao, Geffken, Ezekiel A et al. · 2022 · eLife
- The emergence of melatonin in oncology: Focus on colorectal cancerEmilio Gil‐Martín, Javier Egea, Russel Joseph Reiter, Alejandro Romero · 2019 · Medicinal Research Reviews
- Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathwayJian Song, Qiu-Lei Gao, Bowen Wu, Ting Zhu, Xinxin Cui, Chengjun Jin, Shuyu Wang, Sheng-Hui Wang, Dong‐Jun Fu, Hong‐Min Liu et al. · 2020 · European Journal of Medicinal Chemistry
- Mechanosensation to inflammation: Roles for YAP/TAZ in innate immune cellsVijaykumar S. Meli, Praveen Krishna Veerasubramanian, Timothy L. Downing, Wenqi Wang, Wendy F. Liu · 2023 · Science Signaling
- TNF-α-Induced YAP/TAZ Activity Mediates Leukocyte-Endothelial Adhesion by Regulating VCAM1 Expression in Endothelial CellsHyun-Jung Choi, Na-Eun Kim, Byeong Mo Kim, Miran Seo, Ji Hoe Heo · 2018 · International Journal of Molecular Sciences
- Yes-associated protein 1 is required for proliferation and function of bovine granulosa cells in vitro†Michele R. Plewes, Xiaoying Hou, Pan Zhang, Aixin Liang, Guohua Hua, Jennifer R. Wood, Andrea S. Cupp, Xiangmin Lv, Cheng Wang, John S. Davis · 2019 · Biology of Reproduction
- The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1Han Han, Hiroki J. Nakaoka, Line Hofmann, Jeff Jiajing Zhou, Clinton Yu, Lisha Zeng, Junyu Nan, Gayoung Seo, Rebecca Elizabeth Vargas, Bing Yang et al. · 2022 · Nature Cell Biology
- Lateral Inhibition in Cell Specification Mediated by Mechanical Signals Modulating TAZ ActivityPeng Xia, Daniel Gütl, Vanessa Zheden, Carl‐Philipp Heisenberg · 2019 · Cell
- Hippo signaling is intrinsically regulated during cell cycle progression by APC/C Cdh1Wantae Kim, Yong Suk Cho, Xiaohui Wang, Ogyi Park, Xueyan Ma, Hanjun Kim, Wenjian Gan, Eek‐hoon Jho, Boksik Cha, Yun-ji Jeung et al. · 2019 · Proceedings of the National Academy of Sciences
- Cryo-EM structure of the Hippo signaling integrator human STRIPAKByung‐Cheon Jeong, Sung Jun Bae, Lisheng Ni, Xuewu Zhang, Xiao‐chen Bai, Xuelian Luo · 2021 · Nature Structural & Molecular Biology
- Cellular and molecular basis of liver regenerationSushant Bangru, Auinash Kalsotra · 2020 · Seminars in Cell and Developmental Biology
- Genome-wide interrogation of gene functions through base editor screens empowered by barcoded sgRNAsPing Xu, Zhiheng Liu, Ying Liu, Huazheng Ma, Yiyuan Xu, Ying Bao, Shiyou Zhu, Zhongzheng Cao, Zeguang Wu, Zhuo Long Zhou et al. · 2021 · Nature Biotechnology
- Hippo pathway activation mediates chemotherapy-induced anti-cancer effect and cardiomyopathy through causing mitochondrial damage and dysfunctionGang She, Jin-Chan Du, Wei Wu, Tian-Tian Pu, Yu Zhang, Ru‐Yue Bai, Yi Zhang, Zheng‐Da Pang, Hui‐Fang Wang, Yujie Ren et al. · 2023 · Theranostics
- α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo PathwayAfshin Varzavand, Will Hacker, Deqin Ma, Katherine Nicole Gibson-Corley, Maria Isabel Hawayek, Omar J. Tayh, James A. Brown, Michael D. Henry, Christopher S. Stipp · 2016 · Cancer Research
- Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and BeyondSayan Chakraborty, Wanjin Hong · 2018 · Cancers
- A Reciprocal Role of the Smad4-Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem CellsJin Seok Park, Minbeom Kim, No‐Joon Song, Jun-Hyeong Kim, Dongyeob Seo, Jihyung Lee, Su Myung Jung, Jae Young Lee, Jaewon Lee, Youn Sook Lee et al. · 2018 · Stem Cells
- Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesisZhijun Liu, Patricia P. Yee, Yiju Wei, Zhenqiu Liu, Yuka Imamura Kawasawa, Wei Li · 2019 · Journal of Cell Science
- Nuclear Functions of the Tyrosine Kinase SrcGiulia Bagnato, Martina Leopizzi, Enrica Urciuoli, Barbara Peruzzi · 2020 · International Journal of Molecular Sciences
- Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1Jiagui Song, Tianzhuo Wang, Xiaochun Chi, Xiaofan Wei, Sidi Xu, Miao Yu, Huiying He, Ji Ma, Xueying Li, Juan Du et al. · 2019 · Cell Reports
- Epithelial to Mesenchymal Transition: Key Regulator of Pancreatic Ductal Adenocarcinoma Progression and ChemoresistanceKostas Palamaris, Evangelos S. Felekouras, Stratigoula Sakellariou · 2021 · Cancers
- The Hippo–YAP/TAZ Signaling Pathway in Intestinal Self-Renewal and Regeneration After InjuryFeihong Deng, Zengrong Wu, Fei Zou, Su Wang, Xuehong Wang · 2022 · Frontiers in Cell and Developmental Biology
- A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK/PI3K induced malignant growthMarie Mayrhofer, Victor Gourain, Markus Reischl, Pierre Affaticati, Arnim Jenett, Jean‐Stéphane Joly, Matteo Benelli, Francesca Demichelis, Pietro Luigi Poliani, Dirk Sieger et al. · 2016 · Disease Models & Mechanisms
- CDK7 regulates organ size and tumor growth by safeguarding the Hippo pathway effector Yki/Yap/Taz in the nucleusYong Suk Cho, Shuang Li, Xiaohui Wang, Jian Zhu, Shu Zhuo, Yuhong Han, Tao Yue, Yingzi Yang, Jin Jiang · 2019 · Genes & Development
- Dysregulation of the Hippo pathway signaling in aging and cancerYiu To Yeung, Angélica Guerrero‐Castilla, Mercedes Cano, Mario F. Muñoz, Antonio Ayala, Sandro Argüelles · 2019 · Pharmacological Research
- Neuronal Hippo signaling: From development to diseasesManas Ranjan Sahu, Amal Chandra Mondal · 2020 · Developmental Neurobiology
- New insights into the Hippo/YAP pathway in idiopathic pulmonary fibrosisMingyao Sun, Yangyang Sun, Ziru Feng, Xinliang Kang, Weijie Yang, Yongan Wang, Yuan Luo · 2021 · Pharmacological Research
- MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membraneAngela R.M. Kurz, Monika Pruenster, Ina Rohwedder, Mahalakshmi Ramadass, Kerstin Schäfer, Ute Harrison, Gabriel Gouveia, Claudia Nußbaum, Roland Immler, Johannes Roman Wiessner et al. · 2016 · Journal of Clinical Investigation
- Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinomaWong, Kwong-Fai, Liu, Angela M., Hong, Wanjin, Xu, Zhi, Luk, John M. · 2016 · Oncotarget
- Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signalingYang Tang, Min Chen, Li Zhou, Jian Ma, Yehua Li, Hui Zhang, Zhubing Shi, Qi Xu, Xiaoman Zhang, Ziyang Gao et al. · 2019 · Cell Discovery
- The Histone Methyltransferase G9a Promotes Cholangiocarcinogenesis Through Regulation of the Hippo Pathway Kinase LATS2 and YAP Signaling PathwayWenbo Ma, Chang Han, Jinqiang Zhang, Kyoungsub Song, Weina Chen, Hyunjoo Kwon, Tong Wu · 2020 · Hepatology
- The crosstalk between lncRNAs and the Hippo signalling pathway in cancer progressionChao Tu, Kexin Yang, Lu Wan, Jieyu He, Lin Qi, Wanchun Wang, Qiong Lu, Zhihong Li · 2020 · Cell Proliferation
- ACTN1 supports tumor growth by inhibiting Hippo signaling in hepatocellular carcinomaQian Chen, Xiaowei Zhou, Aijun Zhang, Kang He · 2021 · Journal of Experimental & Clinical Cancer Research
- New strategies in soft tissue sarcoma treatmentMariella Spalato Ceruso, Nathan El-Ghazzi, Antoîne Italiano · 2024 · Journal of Hematology & Oncology
- Dual roles of yes-associated protein (YAP) in colorectal cancerChunlin Ou, Zhenqiang Sun, Shen Li, Guiyuan Li, Xiayu Li, Jian Ma · 2017 · Oncotarget
- YAP1 is essential for osteoclastogenesis through a TEADs-dependent mechanismLiming Zhao, Hanfeng Guan, Chao Song, Yuting Wang, C Y Liu, Cong Cai, Hui Liu, Hui Liu, Libo Zhao, Jun Xiao · 2018 · Bone
- Advances in IKBKE as a potential target for cancer therapyMin Yin, Xin Wang, Jie Lu · 2019 · Cancer Medicine
- Interplay of mitochondrial fission-fusion with cell cycle regulation: Possible impacts on stem cell and organismal agingBrian Spurlock, Jennifer M. A. Tullet, John L. Hartman, Kasturi Mitra · 2020 · Experimental Gerontology
- Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung RepairQian Chen, Jalees Rehman, Manwai Chan, Panfeng Fu, Steven M. Dudek, Viswanathan Natarajan, Asrar B. Malik, Yu‐Ru Liu · 2020 · Cell Reports
- Insect Gut RegenerationPeng Zhang, Bruce A. Edgar · 2021 · Cold Spring Harbor Perspectives in Biology
- Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathwayLiu, Jie, Li, Juan, Li, Pingping, Wang, Yaochun, Liang, Zheyong, Jiang, Yina, Li, Jing, Feng, Chen, Wang, Ruiqi, Chen, He et al. · 2017 · Scientific Reports
- Emerging Principles in the Transcriptional Control by YAP and TAZAlejandro Lopez-Hernandez, Silvia Sberna, Stefano Campaner · 2021 · Cancers
- Icariin attenuates bleomycin-induced pulmonary fibrosis by targeting Hippo/YAP pathwayWenjing Du, Zhao Tang, Fangyong Yang, Xijun Liu, Jingcheng Dong · 2021 · Biomedicine & Pharmacotherapy
- Targeting Mechanotransduction at the Transcriptional Level: YAP and BRD4 Are Novel Therapeutic Targets for the Reversal of Liver FibrosisAltynbek Zhubanchaliyev, Aibar Temirbekuly, Kuralay Kongrtay, Leah C. Wanshura, Jeannette Kunz · 2016 · Frontiers in Pharmacology
- Deubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathwayChu Zhu, Xinyan Ji, Haitao Zhang, Qi Zhou, Xiaolei Cao, Mei Tang, Yuan Si, Huan Yan, Li Li, Tingbo Liang et al. · 2017 · Journal of Biological Chemistry
- YAP and TAZ are dispensable for physiological and malignant haematopoiesisElisa Donato, Francesca Biagioni, Andrea Bisso, Marieta Cagánová, Bruno B. Amati, Stefano Campaner · 2018 · Leukemia
- Zyxin promotes colon cancer tumorigenesis in a mitotic phosphorylation-dependent manner and through CDK8-mediated YAP activationJiuli Zhou, Yongji Zeng, Lian Cui, Xingcheng Chen, Seth Stauffer, Zhan Wang, Fang Yu, Subodh M. Lele, Geoffrey A. Talmon, Adrian R. Black et al. · 2018 · Proceedings of the National Academy of Sciences
- Activation of Aurora A kinase increases YAP stability via blockage of autophagyPeng Wang, Ying Gong, Tao Guo, Man Li, Lei Fang, Shengchen Yin, Kamran I. Muhammad, Yang Liu, Jie Xu, Lingzhi Xu et al. · 2019 · Cell Death and Disease
- The Hippo PathwayCathie M. Pfleger · 2017 · Current topics in developmental biology/Current Topics in Developmental Biology
- Radiation-induced YAP activation confers glioma radioresistance via promoting FGF2 transcription and DNA damage repairYu Zhang, Yan Wang, Ding Zhou, Kai Wang, Xu Wang, Xiang Wang, Yang Jiang, Min Zhao, Rutong Yu, Xiuping Zhou · 2021 · Oncogene
- Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injuryMichinari Nakamura, Peiyong Zhai, Dominic P. Del Re, Yasuhiro Maejima, Junichi Sadoshima · 2016 · JCI Insight
- The NDR/LATS protein kinases in immunology and cancer biologyAhmad A.D. Sharif, Alexander Hergovich · 2017 · Seminars in Cancer Biology
- Hippo/YAP signaling pathway mitigates blood-brain barrier disruption after cerebral ischemia/reperfusion injuryPian Gong, Zhan Zhang, Changlin Zou, Qi Tian, Xuemei Chen, Michael Hong, Xi Liu, Qianxue Chen, Xu Zhou, Mingchang Li et al. · 2018 · Behavioural Brain Research
- Tumor organoids: From inception to future in cancer researchLiang Yang, Shuo Yang, Xinyu Li, Bowen Li, Yan Li, Xiaodong Zhang, Yingbo Ma, Xueqiang Peng, Hongyuan Jin, Qing Fan et al. · 2019 · Cancer Letters
- Vascular endothelial growth factor enhances tendon‐bone healing by activating Yes‐associated protein for angiogenesis induction and rotator cuff reconstruction in ratsYao Huang, Min Pan, Hao Shu, Bing He, Fucheng Zhang, Luning Sun · 2019 · Journal of Cellular Biochemistry
- Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcomaCorinne Bouvier, Nicolas Macagno, Quy Pham Nguyen, Anderson Loundou, Carine Jiguet‐Jiglaire, Jean‐Claude Gentet, Jean-Luc Jouve, Alexandre Rochwerger, Jean-Camille Mattei, Daniel Bouvard et al. · 2016 · Oncotarget
- Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEADYannick Mesrouze, Fedir M. Bokhovchuk, Marco Meyerhofer, Patrizia Fontana, Catherine Zimmermann, Typhaine Martin, Clara Delaunay, Dirk Erdmann, Tobias Schmelzle, Patrick Chêne · 2017 · eLife
- VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast CancerYinglong Zhang, He Shen, Henry G. Withers, Nuo Yang, Kayla E. Denson, Ashley L. Mussell, Alexander M. Truskinovsky, Qingyu Fan, Irwin H. Gelman, Costa G. Frangou et al. · 2017 · Scientific Reports
- Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ–TEAD BiosensorsKazem Nouri, Taha Azad, Min Ling, Helena J. Janse van Rensburg, Alexander Pipchuk, He Shen, Yawei Hao, Jianmin Zhang, Xiaolong Yang · 2019 · Cancers