Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

Yu, Fa-Xing, Zhao, Bin, Guan, Kun-Liang·2015·Cell

DOI 10.1016/j.cell.2015.10.044

Cited by (1,005)

Items 901–1,000 of 1,005

WBP2 negatively regulates the Hippo pathway by competitively binding to WWC3 with LATS1 to promote non-small cell lung cancer progression
Qiang Han, Xuezhu Rong, Xuyong Lin, Xiupeng Zhang, Chuifeng Fan, Huanyu Zhao, Enhua Wang · 2021 · Cell Death and Disease
Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection
Xufeng Luo, Rui Zhang, Mengji Lu, Shi Liu, Hideo Andreas Baba, Guido Gerken, Heiner H. Wedemeyer, Ruth Broering · 2021 · Frontiers in Immunology
Pan-cancer analysis, cell and animal experiments revealing TEAD4 as a tumor promoter in ccRCC
Fang Li, Yun Feng, Qiuyu Jiang, Jinyuan Zhang, Fei Wu, Qian Li, Xintao Jing, Xiaofei Wang, Chen Yu Huang · 2022 · Life Sciences
PDE4D binds and interacts with YAP to cooperatively promote HCC progression
Huili Ren, Yingxiang Chen, Ao Zhou, Qi Cheng, Xiaoyan Yang, Hua Tao, Lixin Zhao, Ao Shen, Peiyuan Li, Qin Fu · 2022 · Cancer Letters
Kank1 Is Essential for Myogenic Differentiation by Regulating Actin Remodeling and Cell Proliferation in C2C12 Progenitor Cells
Mai Thi Nguyen, Wan Lee · 2022 · Cells
Bip-Yorkie interaction determines oncogenic and tumor-suppressive roles of Ire1/Xbp1s activation
Shuai Yang, Hua Jiang, Weixiang Bian, Wenyan Xu, Yifan Guo, Sha Song, Jiadong Zheng, Xiaoyu Kuang, Chenxi Wu, Xiang Ding et al. · 2022 · Proceedings of the National Academy of Sciences
Kidney tubular transcription co-activator, Yes-associated protein 1 (YAP), controls the expression of collecting duct aquaporins and water homeostasis
Yu Zhang, Huihui Huang, Yonglun Kong, Chunhua Xu, Liujiang Dai, Xiaoqiang Geng, Yujie Deng, Yang Wang, Yang Liu, Chenling Meng et al. · 2022 · Kidney International
TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1
Zonglong Wu, Liyuan Ge, Lulin Ma, Min Lu, Yimeng Song, Shaohui Deng, Peichen Duan, Tan Du, Yaqian Wu, Zhanyi Zhang et al. · 2023 · Cell & Bioscience
Phase separation in gene transcription control
Chengyu Li, Zhuo Li, Zhibing Wu, Huasong Lu · 2023 · Acta Biochimica et Biophysica Sinica
Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity
Yu‐Chuan Yan, Guang-Xiao Meng, Chuncheng Yang, Yafei Yang, Siyu Tan, Lun‐Jie Yan, Zi‐Niu Ding, Yunlong Ma, Zhao‐Ru Dong, Tao Li · 2023 · Cell Death and Disease
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells
Xiaolong Wei, Jun Ye, Yangyang Shang, Haoyuan Chen, Shanxi Liu, Li Liu, Rongquan Wang · 2017 · Oncotarget
Fufang Xueshuantong protects retinal vascular endothelial cells from high glucose by targeting YAP
Wei Xing, Yongli Song, Hongli Li, Zhenglin Wang, Yan Ling Wu, Chun Li, Yong Wang, Yonggang Liu, Wei Wang, Jing Han · 2019 · Biomedicine & Pharmacotherapy
Mechanical Signaling in Dental Pulp Stem Cells
Jiahe Zhao, Wen Du, Daimo Guo, Siyi Wang, Wei Ting Du · 2023 · Frontiers in Bioscience-Landmark
YAP/TAZ as Molecular Targets in Skeletal Muscle Atrophy and Osteoporosis
Youngjoo Kwon · 2024 · Aging and Disease
Long noncoding RNA kcna3 inhibits the progression of colorectal carcinoma through down-regulating YAP1 expression
Xiaolin Zhong, Muhan Lü, Juyi Wan, Tiejun Zhou, Bo Qin · 2018 · Biomedicine & Pharmacotherapy
PLOD1, a target of miR-34c, contributes to cell growth and metastasis via repressing LATS1 phosphorylation and inactivating Hippo pathway in osteosarcoma
Xiaolin Wu, Hongfei Xiang, Wenbin Cong, Huiying Yang, Guoqing Zhang, Yan Wang, Zhu Guo, Yan‐Qing Shen, Bohua Chen · 2020 · Biochemical and Biophysical Research Communications
The cross-talk between the Hippo signaling pathway and autophagy:implications on physiology and cancer
Fengyuan Tang, Gerhard Christofori · 2020 · Cell Cycle
Yes-Associated Protein 1: Role and Treatment Prospects in Orthopedic Degenerative Diseases
Wenqing Xie, Wenfeng Xiao, Kun Tang, Liyang Zhang, Yusheng Li · 2020 · Frontiers in Cell and Developmental Biology
New Insights into YES-Associated Protein Signaling Pathways in Hematological Malignancies: Diagnostic and Therapeutic Challenges
Alessandro Allegra, Giovanni Pioggia, Vanessa Innao, Caterina Musolino, Sebastiano Gangemi · 2021 · Cancers
ZNF213 negatively controls triple negative breast cancer progression via Hippo/YAP signaling
Yun Liu, Peng Su, Wuchen Zhao, Xin Li, Xiao Yang, Jianing Fan, Huijie Yang, Cheng Yan, Lanzhi Mao, Yinlu Ding et al. · 2021 · Cancer Science
Biological Significance of YAP/TAZ in Pancreatic Ductal Adenocarcinoma
Hiromitsu Hayashi, Norio Uemura, Zhao Liu, Kazuki Matsumura, Hiroki Sato, Yuta Shiraishi, Hideo Andreas Baba · 2021 · Frontiers in Oncology
Hippo/yes-associated protein signaling functions as a mechanotransducer in regulating vascular homeostasis
Huizhen Lv, Ding Ai · 2021 · Journal of Molecular and Cellular Cardiology
TAZ exhibits phase separation properties and interacts with Smad7 and β-catenin to repress skeletal myogenesis
Soma Tripathi, Tetsuaki Miyake, Jonathan Kelebeev, John C. McDermott · 2021 · Journal of Cell Science
Redox-Unlockable Nanoparticle-Based MST1 Delivery System to Attenuate Hepatic Steatosis via the AMPK/SREBP-1c Signaling Axis
Yuhan Li, Jing‐Jun Nie, Yuhui Yang, Jianning Li, Jiarui Li, Xianxian Wu, Xing Liu, Dafu Chen, Zhiwei Yang, Fu‐Jian Xu et al. · 2022 · ACS Applied Materials & Interfaces
Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning
Jens Stepan, Daniel E. Heinz, Frederik Dethloff, Thomas Bajaj, Andreas Zellner, Kathrin Hafner, Svenja Wiechmann, Sarah Mackert, Yara Mecdad, Michael Rabenstein et al. · 2022 · Cell Reports
Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migration
Maria Camila Fetiva, Franziska Liss, Dörthe Gertzmann, Julius Thomas, Benedikt Gantert, Magdalena Vogl, Nataliia Sira, Grit Weinstock, Susanne Kneitz, Carsten Patrick Ade et al. · 2023 · Nucleic Acids Research
Innate immune and proinflammatory signals activate the Hippo pathway via a Tak1-STRIPAK-Tao axis
Yinan Yang, Huijing Zhou, Xiawei Huang, Chengfang Wu, Kewei Zheng, Jingrong Deng, Yonggang Zheng, Jiahui Wang, Xiaofeng Chi, Xianjue Ma et al. · 2024 · Nature Communications
Epidermal YAP2-5SA-ΔC Drives β-Catenin Activation to Promote Keratinocyte Proliferation in Mouse Skin In Vivo
Bassem Akladios, Veronica Mendoza‐Reinoso, Michael Susithiran Samuel, Edna C. Hardeman, Kiarash Khosrotehrani, Brian Key, Annemiek Beverdam · 2016 · Journal of Investigative Dermatology
Role of ESCRT component HD-PTP/PTPN23 in cancer
Marie‐Claude Gingras, Jalal M. Kazan, Arnim Pause · 2017 · Biochemical Society Transactions
IL ‐6 Triggers the Migration and Invasion of Oestrogen Receptor‐Negative Breast Cancer Cells via Regulation of Hippo Pathways
Lingmi Hou, Shaoli Xie, Guanwu Li, Bin Xiong, Gao Yanchun, Xiaobo Zhao, Jiani Hu, Shishan Deng, Jun Jiang · 2018 · Basic & Clinical Pharmacology & Toxicology
Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ
Paraskevi Xekouki, Emily J. Lodge, Jakob Matschke, Alice Santambrogio, John Richard Apps, Ariane Sharif, Thomas S. Jacques, Simon J B Aylwin, Vincent Prévot, Ran Li et al. · 2018 · Endocrine Related Cancer
Cyclopeptide RA-V Inhibits Organ Enlargement and Tumorigenesis Induced by YAP Activation
Xinyan Ji, Lihua Song, Sheng Li, Anhui Gao, Yang Zhao, Shixun Han, Yuchao Zhang, Chu Zhu, Simeng Zhao, Zhe Wang et al. · 2018 · Cancers
Identification of potential biomarkers and pivotal biological pathways for prostate cancer using bioinformatics analysis methods
Zihao He, Xiaolu Duan, Guohua Zeng · 2019 · PeerJ
Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis
Duo Xu, Shun‐Qing Liang, Yang Zhang, Haitang Yang, Rémy Bruggmann, Simone Oberhaensli, Sabina Berezowska, Thomas M. Marti, Sean R. R. Hall, Patrick Dorn et al. · 2021 · Cell Death and Disease
Understanding the Role of Yes-Associated Protein (YAP) Signaling in the Transformation of Lens Epithelial Cells (EMT) and Fibrosis
Aftab Taiyab, Yasmine Belahlou, Vanessa Wong, Pandi Saranya, Madhu Shekhar, Chidambaranathan Gowri Priya, Judith A. West‐Mays · 2023 · Biomolecules
The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
Dae Jin Jeong, Jee‐Hyun Um, Young Yeon Kim, Dong Jin Shin, Sangwoo Im, Kang‐Min Lee, Yun‐Hee Lee, Dae‐Sik Lim, Donghoon Kim, Jeanho Yun · 2024 · Experimental & Molecular Medicine
FOXP4 Is a Direct YAP1 Target That Promotes Gastric Cancer Stemness and Drives Metastasis
Xiaoli Liu, Bonan Chen, Fuda Xie, Kit Yee Wong, Alvin H.K. Cheung, Jinglin Zhang, Qian Ju Wu, Canbin Fang, Jintao Hu, Shouyu Wang et al. · 2024 · Cancer Research
PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability
Sandra M. Martín‐Guerrero, Pedro Casado, Maruan Hijazi, Vinothini Rajeeve, Julio Plaza‐Díaz, Francisco Abadía‐Molina, Julio Navascués, Miguel Ángel Cuadros, Pedro R. Cutillas, David Martín‐Oliva · 2020 · Biochemical Journal
MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway
Jinqiu Lu, Zonghao Hu, Yujie Deng, Qingzhe Wu, Ming Wu, Hai Xin Song · 2021 · Journal of Biological Chemistry
A Comparative Analysis of Hippo Signaling Pathway Components during Murine and Bovine Early Mammalian Embryogenesis
Jyoti Nanda Sharma, Monica Antenos, Pavneesh Madan · 2021 · Genes
The essential role of TAZ in normal tissue homeostasis
Mi Gyeong Jeong, Hyo Kyeong Kim, Eun Sook Hwang · 2021 · Archives of Pharmacal Research
Upregulation of KDM6B contributes to lipopolysaccharide-induced anxiety-like behavior via modulation of VGLL4 in mice
Yangping Shentu, Qiuyun Tian, Jinge Yang, Xiaoyuan Liu, Yujiao Han, Dichen Yang, Nan Zhang, Xiaofang Fan, Ping Wang, Jianshe Ma et al. · 2021 · Behavioural Brain Research
Gout‐induced endothelial impairment: The role of SREBP2 transactivation of YAP
Zunlan Zhao, Yingshuai Zhao, Yuqing Zhang, Weili Shi, Xiqing Li, John Y.‐J. Shyy, Ming He, Liuyi Wang · 2021 · The FASEB Journal
Hippo-YAP signaling in digestive system tumors.
Feng Yin, Jixin Dong, Liang‐I Kang, Xiuli Liu · 2021 · PubMed Central
A Yes-Associated Protein (YAP) and Insulin-Like Growth Factor 1 Receptor (IGF-1R) Signaling Loop Is Involved in Sorafenib Resistance in Hepatocellular Carcinoma
Mai-Huong Thi Ngo, Sue-Wei Peng, Yung‐Che Kuo, Chung‐Yen Lin, Ming–Heng Wu, Chia-Hsien Chuang, Cheng-Xiang Kao, Han-Yin Jeng, Gee‐Way Lin, Thai‐Yen Ling et al. · 2021 · Cancers
KAT6A is associated with sorafenib resistance and contributes to progression of hepatocellular carcinoma by targeting YAP
Yan Jin, Ruonan Yang, Jingyi Ding, Fengqi Zhu, Cunle Zhu, Qingguo Xu, Jinzhen Cai · 2021 · Biochemical and Biophysical Research Communications
Yes-Associated Protein Is Required for ZO-1-Mediated Tight-Junction Integrity and Cell Migration in E-Cadherin-Restored AGS Gastric Cancer Cells
Seon-Young Kim, Song-Yi Park, Hwanseok Jang, Yongdoo Park, Sun‐Ho Kee · 2021 · Biomedicines
Willin/FRMD6: A Multi-Functional Neuronal Protein Associated with Alzheimer’s Disease
Doris Chen, Wanjia Yu, Laura Aitken, Frank J. Gunn‐Moore · 2021 · Cells
The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice
Ariane Lalonde-Larue, Alexandre Boyer, Esdras Corrêa Dos Santos, Derek Boerboom, Daniel J. Bernard, Gustavo Zamberlam · 2021 · Endocrinology
Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis
Yujuan Jin, Qiqi Zhao, Weikang Zhu, Yan Feng, Tian Xiao, Peng Zhang, Liyan Jiang, Yingyong Hou, Chenchen Guo, Hsin‐Yi Huang et al. · 2021 · National Science Review
Estrogen Regulates the Expression and Localization of YAP in the Uterus of Mice
Sohyeon Moon, Ok‐Hee Lee, Byeongseok Kim, Jinju Park, Semi Hwang, Siyoung Lee, Giwan Lee, Hyukjung Kim, Hyuk Song, Kwonho Hong et al. · 2022 · International Journal of Molecular Sciences
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation
Mahan Si, Yujia Song, Xiaohui Wang, Dong Wang, Xiaohui Liu, Xian‐Jun Qu, Zhiyu Song, Xinfeng Yu · 2022 · Cell & Bioscience
The hippo kinases MST1/2 in cardiovascular and metabolic diseases: A promising therapeutic target option for pharmacotherapy
Yunfei Yin, Mingyue Tan, Lianhua Han, Lei Zhang, Yue Zhang, Jun Zhang, Wanqian Pan, Jiaxiang Bai, Tingbo Jiang, Hongxia Li · 2023 · Acta Pharmaceutica Sinica B
Phase separation of YAP-MAML2 differentially regulates the transcriptome
Chan-I Chung, Junjiao Yang, Xiaoyu Yang, Hongjiang Liu, Zhimin Ma, Frank Szulzewsky, Eric C. Holland, Yin Shen, Xiaokun Shu · 2024 · Proceedings of the National Academy of Sciences
Targeting cardiomyocyte cell cycle regulation in heart failure
Chaonan Zhu, Ting Yuan, Jaya Krishnan · 2024 · Basic Research in Cardiology
Identification of Cdk1–LATS–Pin1 as a Novel Signaling Axis in Anti-tubulin Drug Response of Cancer Cells
Benjamin Yeung, Prem Khanal, Virja Mehta, Laura Trinkle‐Mulcahy, Xiaolong Yang · 2018 · Molecular Cancer Research
Vector Analysis of Cytoskeletal Structural Tension and the Mechanisms that Underpin Spectrin-Related Forces in Pyroptosis
Tingting Chen, Yichen Guo, Jinjun Shan, Jiarui Zhang, Xu Shen, Jun Guo, Margaret Liu · 2018 · Antioxidants and Redox Signaling
Deficiency of Yes-Associated Protein Induces Cataract in Mice
Qing He, Yuhao Gao, Tongxing Wang, Lujun Zhou, Wenxia Zhou, Zengqiang Yuan · 2018 · Aging and Disease
The Hippo Signaling Pathway in Regenerative Medicine
Lixin Hong, Yuxi Li, Qingxu Liu, Qinghua Chen, Lanfen Chen, Dawang Zhou · 2018 · Methods in molecular biology
Calotropin activates YAP through downregulation of LATS1 in colorectal cancer cells
Limin Zhou, Luliang Cai, Yanzi Guo, Huanyu Zhang, Peng Wang, Guohui Yi, Yonghao Huang · 2019 · OncoTargets and Therapy
Interaction of YAP1 and mTOR promotes bladder cancer progression
Mingxi Xu, Meng Gu, Juan Zhou, Jun Da, Zhong Wang · 2019 · International Journal of Oncology · Retracted
Human telomerase reverse transcriptase is a novel target of Hippo‐YAP pathway
Qian Zhang, Ning Liu, Junjie Bai, Qi Zhou, Jian Mao, Lu Xu, Jiang Liu, Haibin Wei, Chengcheng Ren, Xiaoying Wu et al. · 2020 · The FASEB Journal
WWC1 and NF2 Prevent the Development of Intrahepatic Cholangiocarcinoma by Regulating YAP/TAZ Activity through LATS in Mice.
Jaeoh Park, Jeong Sik Kim, Ji Hae Nahm, Sang Kyum Kim, Da-Hye Lee, Dae‐Sik Lim · 2020 · PubMed Central
A SMAD1/5-YAP signaling module drives radial glia self-amplification and growth of the developing cerebral cortex
Sònia Najas, Isabel Pijuan, Anna Esteve‐Codina, Susana Usieto, Juan D. Martinez, An Zwijsen, Maria Lourdes Arbonés, Elisa Martı́, Gwenvaël Le Dréau · 2020 · Development
WISP2 promotes cell proliferation via targeting ERK and YAP in ovarian cancer cells
Zi-Qing Shi, Ziyan Chen, Han Yao, Heng-Yan Zhu, Meng-Dan Lyu, Han Zhang, Yi Zhang, Liuqing Yang, Weiwei Pan · 2020 · Journal of Ovarian Research
Upregulation of miR-1254 promotes Hepatocellular Carcinoma Cell Proliferation, Migration, and Invasion via Inactivation of the Hippo-YAP signaling pathway by decreasing PAX5
Xu Lu, Chao Yang, Yuanchang Hu, Jian Xu, Chengyu Shi, Jianhua Rao, Wei-Xin Yu, Feng Cheng · 2020 · Journal of Cancer
Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice
Stepan, Jens, Heinz, Daniel E., Dethloff, Frederik, Wiechmann, Svenja, Martinelli, Silvia, Hafner, Kathrin, Ebert, Tim, Junglas, Ellen, Häusl, Alexander S., Pöhlmann, Max L. et al. · 2024 · Science Signaling
Current landscape of targeted therapy in esophageal squamous cell carcinoma
Amane Jubashi, Daisuke Kotani, Takashi Kojima, Naoko Takebe, Kohei Shitara · 2024 · Current Problems in Cancer
Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo
Yuhang Lu, Ziqin Yan, Jiaqi Sun, Chenxu Wang, Lan Xu, Xilin Lyu, Xiancheng Wang, Jianfeng Lou, He Huang, Linghua Meng et al. · 2025 · Journal of Medicinal Chemistry
Mechanobiology in Action: Biomaterials, Devices, and the Cellular Machinery of Force Sensing
Miriam Lucariello, Maria Luisa Valicenti, Samuele Giannoni, Leonardo Donati, Ilaria Armentano, Francesco Morena, Sabata Martino · 2025 · Biomolecules
Rottlerin exhibits antitumor activity via down-regulation of TAZ in non-small cell lung cancer
Zhe Zhao, Nana Zheng, Lixia Wang, Yingying Hou, Xiuxia Zhou, Zhiwei Peter Wang · 2016 · Oncotarget
A genome-wide microRNA screen identifies regulators of tetraploid cell proliferation
Marc A. Vittoria, Elizabeth M. Shenk, Kevin P. O’Rourke, Amanda Florence Bolgioni, Sanghee Lim, Victoria Kacprzak, Ryan J. Quinton, Neil J. Ganem · 2018 · Molecular Biology of the Cell
Heterozygous Loss of Yap1 in Mice Causes Progressive Cataracts
Qingxian Lu, Yingnan Zhang, Ramesh B. Kasetti, Subhash Gaddipati, Naresh Kumar CVM, Douglas Borchman, Qiutang Li · 2020 · Investigative Ophthalmology & Visual Science
PIN1 facilitates ubiquitin-mediated degradation of serine/threonine kinase 3 and promotes melanoma development via TAZ activation
Garam Kim, Poshan Yugal Bhattarai, Sung‐Chul Lim, Jin Young Kim, Hong Seok Choi · 2020 · Cancer Letters
Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo‐Independent Regulation of Heat Shock Protein 70 Family Members
Mairene Coto‐Llerena, Nadia Tosti, Stephanie Taha‐Mehlitz, Venkatesh Kancherla, Viola Paradiso, John Gallon, Gaia Bianco, Andrea Garofoli, Souvik Ghosh, Fengyuan Tang et al. · 2021 · Hepatology Communications
Hippo-Yap Pathway Orchestrates Neural Crest Ontogenesis
Xiaolei Zhao, Tram P. Le, Shannon Erhardt, Tina O. Findley, Jun Wang · 2021 · Frontiers in Cell and Developmental Biology
Spatiotemporal model of cellular mechanotransduction via Rho and YAP
Javor K. Novev, Mathias Luidor Heltberg, Mogens H. Jensen, Amin Doostmohammadi · 2021 · Integrative Biology
The role of YAP1 in small cell lung cancer
Haruki Saito, Yuki Tenjin, Tatsuya Yamada, Shinji Kudoh, Noritaka Kudo, Mune Sanada, Younosuke Sato, Akira Matsuo, Yorihisa Orita, Takaaki Ito · 2022 · Human Cell
Abnormal lipid synthesis as a therapeutic target for cancer stem cells
Siyu Wang, Qinchao Hu, Tong Wu, Juan Xia, Xiaoan Tao, Bin Cheng · 2022 · World Journal of Stem Cells
Discovering inhibitors of TEAD palmitate binding pocket through virtual screening and molecular dynamics simulation
Yimin Li, Yaqi Li, Chao Ning, Jianda Yue, Cheng Zhang, Xiao Dong He, Ying Wang, Zhonghua Liu · 2022 · Computational Biology and Chemistry
Deletion of Trp53 and Rb1 in Ctsk‐expressing cells drives osteosarcoma progression by activating glucose metabolism and YAP signaling
Yang Li, Shuting Yang, Yang Liu, Shuying Yang · 2022 · MedComm
MARK2 regulates chemotherapeutic responses through class IIa HDAC-YAP axis in pancreatic cancer
Yongji Zeng, Ling Yin, Jiuli Zhou, Renya Zeng, Yi Xiao, Adrian R. Black, Tuo Hu, Pankaj K. Singh, Feng Yin, Surinder K. Batra et al. · 2022 · Oncogene
The molecular basis of the dichotomous functionality of MAP4K4 in proliferation and cell motility control in cancer
Dejana Versamento, Shen Yan, Martin Baumgartner · 2022 · Frontiers in Oncology
Hippo signaling in acute kidney injury to chronic kidney disease transition: Current understandings and future targets
Tahib Habshi, Vishwadeep Shelke, Ajinath Kale, Maciej Lech, Anil Bhanudas Gaikwad · 2023 · Drug Discovery Today
Chemogenetic Minitool for Dissecting the Roles of Protein Phase Separation
Chan-I Chung, Junjiao Yang, Xiaokun Shu · 2023 · ACS Central Science
MST1 mediates doxorubicin-induced cardiomyopathy by SIRT3 downregulation
Leonardo Schirone, Daniele Vecchio, Valentina Valenti, Maurizio Forte, Michela Relucenti, Annalisa Angelini, Tania Zaglia, Sonia Schiavon, Luca D’Ambrosio, Gianmarco Sarto et al. · 2023 · Cellular and Molecular Life Sciences
Coagulation factor VIIa enhances programmed death-ligand 1 expression and its stability in breast cancer cells to promote breast cancer immune evasion
Subhojit Paul, Kaushik Das, Arnab Ghosh, Akash Chatterjee, Avinandan Bhoumick, Abhimanyu Basu, Prosenjit Sen · 2023 · Journal of Thrombosis and Haemostasis
Transcriptional repression of beige fat innervation via a YAP/TAZ-S100B axis
Xun Huang, Xinmeng Li, Hongyu Shen, Yiheng Zhao, Zhao Zhou, Yushuang Wang, Jingfei Yao, Kaili Xue, Dongmei Wu, Yifu Qiu · 2023 · Nature Communications
YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration
Adrian Kwan Ho Loe, Abilasha Rao‐Bhatia, Wei Zhao, Jungeun Kim, Bingxin Guan, Yan Qin, Minji Hong, Hyo Sang Kwak, Xiaoyu Liu, Leyi Zhang et al. · 2023 · Cell Reports
Forces at play: exploring factors affecting the cancer metastasis
Farooq Riaz, Jing Zhang, Fan Pan · 2024 · Frontiers in Immunology
Hippo kinases maintain polarity during directional cell migration in Caenorhabditis elegans
Guoxin Feng, Zhiwen Zhu, Wen‐Jun Li, Qirong Lin, Yongping Chai, Meng‐Qiu Dong, Guangshuo Ou · 2016 · The EMBO Journal
High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis
Tatsuo Michiue, Takayoshi Yamamoto, Y. Yasuoka, Toshiyasu Goto, Takafumi Ikeda, Kei Nagura, Takuya Nakayama, Masanori Taira, Tsutomu Kinoshita · 2017 · Developmental Biology
YAP activation promotes the transdifferentiation of cardiac fibroblasts to myofibroblasts in matrix remodeling of dilated cardiomyopathy
Bo Jin, Jun Zhu, Haiming Shi, Zhichao Wen, Bangwei Wu · 2018 · Brazilian Journal of Medical and Biological Research
An alternatively transcribed TAZ variant negatively regulates JAK‐STAT signaling
Chuantao Fang, Jian Li, Sixian Qi, Yubin Lei, Yan Jun Zeng, Pengcheng Yu, Zhaolan Hu, Yufeng Zhou, Yulong Wang, Ruping Dai et al. · 2019 · EMBO Reports
YAP/TAZ: a promising target for squamous cell carcinoma treatment
Xiaoming Dong, Lingbin Meng, Pinyi Liu, Rui Ji, Xuling Su, Ying Xin, Xin Mei Jiang · 2019 · Cancer Management and Research
On the relationship of YAP and FAK in hMSCs and osteosarcoma cells: Discrimination of FAK modulation by nuclear YAP depletion or YAP silencing
Ayman Husari, Thorsten Steinberg, Martin Philipp Dieterle, Oswald Prucker, Jürgen Rühe, Britta A. Jung, Pascal Tomakidi · 2019 · Cellular Signalling
Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis
Marina Peralta, Laia Ortiz López, Kateřina Jeřábková, Tommaso Lucchesi, Benjamin Vitre, Dong Han, Laurent Guillemot, Chaitanya Dingare, Izabela Sumara, Nadia Mercader et al. · 2020 · Cell Reports
Yes-associated protein is crucial for constitutive androstane receptor-driven hepatocyte proliferation but not for induction of drug metabolism genes in mice
Bhushan, Bharat, Molina, Laura, Koral, Kelly, Stoops, John W., Mars, Wendy M., Banerjee, Swati, Orr, Anne, Paranjpe, Shirish, Monga, Satdarshan P., Locker, Joseph et al. · 2021 · Hepatology
Hippo/MST blocks breast cancer by downregulating WBP2 oncogene expression via miRNA processor Dicer
Shen Kiat Lim, Hossein Tabatabaeian, Ssu Yi Lu, Shinae Kang, Gopinath Meenakshi Sundaram, Prabha Sampath, Siew Wee Chan, Wan Jin Hong, Yoon Pin Lim · 2020 · Cell Death and Disease
Loss ofAnks6leads to YAP deficiency and liver abnormalities
Merlin Airik, Markus Schüler, Blake T. McCourt, Anna‐Carina Weiss, Nathan Herdman, Timo H. Lüdtke, Eugen Widmeier, Donna Beer Stolz, Kari Nichole Nejak‐Bowen, Dean Yimlamai et al. · 2020 · Human Molecular Genetics