Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

Yu, Fa-Xing, Zhao, Bin, Guan, Kun-Liang·2015·Cell

DOI 10.1016/j.cell.2015.10.044

Cited by (1,005)

Items 501–600 of 1,005

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YAP promotes sorafenib resistance in hepatocellular carcinoma by upregulating survivin
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Emerging roles of the Hippo signaling pathway in modulating immune response and inflammation‐driven tissue repair and remodeling
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Advances of targeting the YAP/TAZ-TEAD complex in the hippo pathway for the treatment of cancers
Mengxin Luo, Yongjin Xu, Haifeng Chen, Yiquan Wu, Ao Pang, Junjie Hu, Xiaowu Dong, Jinxin Che, Haiyan Yang · 2022 · European Journal of Medicinal Chemistry
Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutations
Albino Troilo, Erica K. Benson, Davide Esposito, Rachel‐Ann A. Garibsingh, E. Premkumar Reddy, Sathish Kumar Mungamuri, Stuart A. Aaronson · 2016 · Oncotarget
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Eline Sijbesma, Lukasz Skóra, S. Leysen, Luc Brunsveld, Uwe Koch, Peter Nußbaumer, Wolfgang Jahnke, Christian Ottmann · 2017 · Biochemistry
Hippo signaling dysfunction induces cancer cell addiction to YAP
Han Han, Bing Yang, Hiroki J. Nakaoka, Jiadong Yang, Yifan Zhao, Kathern Le Nguyen, Amell Taffy Bishara, Tejas Krishen Mandalia, Wenqi Wang · 2018 · Oncogene
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A five-gene signature predicts overall survival of patients with papillary renal cell carcinoma
Ze Gao, Dong Zhang, Yi Duan, Lei Yan, Yidong Fan, Zhiqing Fang, Zhaoxu Liu · 2019 · PLoS ONE
Targeting cell surface GRP78 enhances pancreatic cancer radiosensitivity through YAP/TAZ protein signaling
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PINK1‐Dependent Mitophagy Regulates the Migration and Homing of Multiple Myeloma Cells via the MOB1B‐Mediated Hippo‐YAP/TAZ Pathway
Shengjun Fan, Trevor T. Price, Wei Huang, Michelle Plue, Jonathan L. Warren, Pasupathi Sundaramoorthy, Barry A. Paul, Daniel M. Feinberg, Nancie J. MacIver, Nelson Jen An Chao et al. · 2020 · Advanced Science
Hippo/YAP Pathway Plays a Critical Role in Effect of GDNF Against Aβ-Induced Inflammation in Microglial Cells
Jie Qing, Xiaoheng Liu, Quan Wu, Mengjie Zhou, Yuwei Zhang, Maryam Mazhar, Xiaoli Huang, Li Wang, Fu‐Qian He · 2020 · DNA and Cell Biology
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PP2Ac/STRN4 negatively regulates STING-type I IFN signaling in tumor-associated macrophages
Winson S. Ho, Isha Mondal, Beisi Xu, Oishika Das, Raymond Sun, Pochin Chiou, Xiaomin Cai, Foozhan Tahmasebinia, Elizabeth McFadden, Caren Yu-Ju Wu et al. · 2023 · Journal of Clinical Investigation
Pharmacological YAP activation promotes regenerative repair of cutaneous wounds
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Pahal Priyanka, Athira Perunelly Gopalakrishnan, Mahammad Nisar, Prathik Basthikoppa Shivamurthy, Mejo George, Levin John, Diya Sanjeev, Tanuja Yandigeri, Sonet Daniel Thomas, Ahmad Rafi et al. · 2024 · The International Journal of Biochemistry & Cell Biology
Tissue inhibitor of metalloproteinase-1 promotes cell proliferation through YAP/TAZ activation in cancer
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Activation of human aortic valve interstitial cells by local stiffness involves YAP-dependent transcriptional signaling
Rosaria Santoro, Denis Scaini, Luisa Ulloa Severino, Francesco Amadeo, Silvia Ferrari, Giacomo Bernava, Gloria Garoffolo, Marco Agrifoglio, Loredana Casalis, Maurizio Pesce · 2018 · Biomaterials
YAP via interacting with STAT3 regulates VEGF-induced angiogenesis in human retinal microvascular endothelial cells
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López-Márquez, Arístides, Carrasco-López, Carlos, Fernández-Méndez, Celia, Santisteban, Pilar · 2021 · Frontiers in Endocrinology
HMGA2 promotes breast cancer metastasis by modulating Hippo-YAP signaling pathway
Jian‐Xin Xu, Fang Xuejiao, Luye Long, Sixuan Wang, Shihan Qian, Jianxin Lyu · 2020 · Cancer Biology & Therapy
NUSAP1 Promotes Gastric Cancer Tumorigenesis and Progression by Stabilizing the YAP1 Protein
Hui Guo, Jian‐Ping Zou, Ling Zhou, Min Zhong, Yan He, Shanshan Huang, Jun Chen, Junhe Li, Jianping Xiong, Ziling Fang et al. · 2021 · Frontiers in Oncology
The Hippo-YAP pathway in various cardiovascular diseases: Focusing on the inflammatory response
Ancheng Zheng, Qishan Chen, Li Zhang · 2022 · Frontiers in Immunology
FSP1-positive fibroblasts are adipogenic niche and regulate adipose homeostasis
Rui Zhang, Yuan Gao, Xiaotong Zhao, Mei Gao, Yanjun Wu, Yingying Han, Yuemei Qiao, Zheng Luo, Li Chun Yang, Jianfeng Chen et al. · 2018 · PLoS Biology
Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice
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Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma
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Lamin Mutations Cause Increased YAP Nuclear Entry in Muscle Stem Cells
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GPR39 Overexpression in OSCC Promotes YAP-Sustained Malignant Progression
Yuchen Jiang, Taiwen Li, Yi‐Ying Wu, Huanji Xu, Changqing Xie, Y. Dong, L. Zhong, Z Wang, Hang Zhao, Yong Zhou et al. · 2020 · Journal of Dental Research
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