Epigenetic mechanisms of longevity and aging
Sen, Payel, Shah, Parisha P., Nativio, Raffaella, Berger, Shelley L.·2016·Cell
Cited by (962)
Items 401–500 of 962
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- Old drug, new tricks: the utility of metformin in infection and vaccination responses to influenza and SARS-CoV-2 in older adultsDominique E. Martin, Andreia N. Cadar, Jenna M. Bartley · 2023 · Frontiers in Aging
- Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescenceAnna Ungvari, Tamás Kiss, Rafał Gulej, Stefano Tarantini, Boglárka Csík, Andriy Yabluchanskiy, Péter Mukli, Anna Csiszár, Melissa L. Harris, Zoltan I. Ungvari · 2024 · GeroScience
- Chromatin remodeling-driven autophagy activation induces cisplatin resistance in oral squamous cell carcinomaSu Young Oh, Jin‐Kyung Kim, Kah Young Lee, Heon‐Jin Lee, Tae‐Geon Kwon, Jin Wook Kim, Sung‐Tak Lee, Dae-Geon Kim, So‐Young Choi, Su‐Hyung Hong · 2024 · Cell Death and Disease
- The tubal epigenome – An emerging target for ovarian cancerHunter D. Reavis, Ronny Drapkin · 2020 · Pharmacology & Therapeutics
- Identification of 5-methylcytosine-related signature for predicting prognosis in ovarian cancerLei Wang, Song Gao · 2021 · Biological Research
- When function follows form: Nuclear compartment structure and the epigenetic landscape of the aging neuronJohannes C. M. Schlachetzki, Tomohisa Toda, Jérôme Mertens · 2020 · Experimental Gerontology
- Transcriptional multiomics reveals the mechanism of seed deterioration in Nicotiana tabacum L. and Oryza sativa L.Jianyu An, Yihan Liu, Jiajun Han, Can He, Min Chen, Xiaobo Zhu, Weimin Hu, Wenjian Song, Jin Hu, Yajing Guan · 2022 · Journal of Advanced Research
- Biosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesisYoshiki Hayashi, Soshiro Kashio, Kazutoshi Murotomi, Shinjiro Hino, Woojin Kang, Kenji Miyado, Mitsuyoshi Nakao, Masayuki Miura, Satoru Kobayashi, Masakazu Namihira · 2022 · Scientific Reports
- Gut Microbiota Composition and Metabolic Potential of Long-Living People in ChinaSiyuan Zhang, Ruihong Ning, Bo Zeng, Feilong Deng, Fanli Kong, Wei Guo, Jiangchao Zhao, Ying Li · 2022 · Frontiers in Aging Neuroscience
- The effect of growth hormone on the metabolome of follicular fluid in patients with diminished ovarian reserveFan He, Fang Wang, Yang Yang, Yuan Zhi, Chengguang Sun, Heng Zou, Huijia Chen, Hongliang Yi, Shan Hu Gao, Shen Zhang et al. · 2023 · Reproductive Biology and Endocrinology
- Whole organism aging: Parabiosis, inflammaging, epigenetics, and peripheral and central aging clocks. The ARS of agingReinald Pamplona, Mariona Jové, José Gómez, Gustavo Barja · 2023 · Experimental Gerontology
- Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegansXinhao Hou, Mingjing Xu, Chengming Zhu, Jianing Gao, Meili Li, Xiangyang Chen, Cheng Sun, Björn Nashan, Jianye Zang, Ying Zhou et al. · 2023 · Nature Communications
- Implication of DNA methylation during lifestyle mediated weight lossSamantha Aurich, Luise Müller, Peter Louis Kovacs, Maria Keller · 2023 · Frontiers in Endocrinology
- DNA methylation and chromatin accessibility predict age in the domestic dogKelly Jin, Brianah M. McCoy, Elisabeth A. Goldman, Viktoria Usova, Victor Tkachev, Alex Chitsazan, Anneke Dixie Kakebeen, Unity Jeffery, Kate E. Creevy, Andrea Elizabeth Wills et al. · 2024 · Aging Cell
- Polyphenolic Compounds: Orchestrating Intestinal Microbiota Harmony during AgingQuélita Cristina Pereira, Isabela Monique Fortunato, Fabrício de Sousa Oliveira, Marisa Claudia Alvarez, Tanila Wood dos Santos, Marcelo Lima Ribeiro · 2024 · Nutrients
- ImAge quantitates aging and rejuvenationMartin Alvarez-Kuglen, Kenta Ninomiya, Haodong Qin, Delany Rodriguez, Lorenzo Fiengo, Chen Farhy, Wei-Mien Hsu, Brian D. Kirk, Aaron P. Havas, Collin Kaufman et al. · 2024 · Nature Aging
- Small molecule-based regulation of gene expression in human astrocytes switching on and off the G-quadruplex control systemsVijay Kumar M J, Jérémie Mitteaux, Zi Wang, Ellery Wheeler, Nitin Tandon, Sung Yun Jung, Robert H. E. Hudson, David Monchaud, Andrey S. Tsvetkov · 2024 · Journal of Biological Chemistry
- Unveiling epigenetic regulation in cancer, aging, and rejuvenation with in vivo reprogramming technologyYuko Sogabe, Hiroshi Seno, Takuya Yamamoto, Yasuhiro Yamada · 2018 · Cancer Science
- Neuron-specific analysis of histone modifications with post-mortem brainsKagari Koshi Mano, Tatsuo Mano, Maho Morishima, Shigeo Murayama, Akira Tamaoka, Shoji Tsuji, Tatsushi Toda, Atsushi Iwata · 2020 · Scientific Reports
- Unravelling Cellular Mechanisms of Stem Cell Senescence: An Aid from Natural Bioactive MoleculesSara Cruciani, Giuseppe Garroni, Giorgio Carlo Ginesu, Angela Fadda, Carlo Ventura, Margherita Maioli · 2020 · Biology
- Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular ZoneZhichao Zhang, Adeel Manaf, Yanjiao Li, Sonia Peña Perez, Rajikala Suganthan, John Arne Dahl, Magnar Bjørås, Arne Klungland · 2019 · Molecular Neurobiology
- Loss of H3K9 trimethylation leads to premature agingAlejandro Ocampo, Calida Mrabti, Gabriela Desdín-Micó, Gabriela Desdín-Micó, Alejandro Alonso Calleja, Alba Vílchez-Acosta, Sara Picó, Alberto Parras, Yulan Piao, Lucas Schoenfeldt et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Ultraviolet irradiation-induced inhibition of histone deacetylase 4 increases the expression of matrix metalloproteinase-1 but decreases that of type I procollagen via activating JNK in human dermal fibroblastsYuri Lee, Mi Hee Shin, Min Kyoung Kim, Chi‐Hyun Park, Hye Sun Shin, Dong Hun Lee, Jin Ho Chung · 2020 · Journal of Dermatological Science
- RNAPII driven post-translational modifications of nucleosomal histonesWai Soon Chan, Amarjeet Kumar, Hidetoshi Kono · 2022 · Trends in Genetics
- Molecular characterization and DNA methylation analysis of carbonic anhydrase (Sp-CA) in the mud crab Scylla paramamosain: Its potential osmoregulation role under carbonate alkalinity stressXiaopeng Wang, Wei Fang, Lei Liu, Yuanyuan Fu, Yueyue Zhou, Dongping Zhou, Xinlian Huang, Changkao Mu, Chunlin Wang · 2023 · Aquaculture Reports
- In Vitro Models of Cell Senescence: A Systematic Review on Musculoskeletal Tissues and CellsFrancesca Veronesi, Deyanira Contartese, Laura Di Sarno, Veronica Borsari, Milena Fini, Gianluca Giavaresi · 2023 · International Journal of Molecular Sciences
- Bacillus Calmette-Guérin vaccination induces a trained innate immunity phenotype in adults over 50 years of age: A randomized trial in Guinea-BissauM. Berendsen, Pauli Bles, Louise Charlotte Johanna de Bree, Kristoffer Jarlov Jensen, Clara Clipet Jensen, Christian Morberg Wejse, Delfim Vicente Mendes, Mihai Gheorghe Netea, Christine Stabell Benn · 2024 · Vaccine
- Downregulation of MLF1 safeguards cardiomyocytes against senescence-associated chromatin openingJian Lv, Qin Chen, Junmei Wang, Ningning Guo, Fang Yu, Qiuxiao Guo, Jiajie Li, Xiao Ma, Hongchao Zhan, Weihao Chen et al. · 2024 · Nucleic Acids Research
- Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissueLore Becker, Melanie Schmitt Nogueira, Caroline Klima, Martin Hrabě de Angelis, Shahaf Peleg · 2018 · Scientific Reports
- The "dark matter" of DNA and the regulation of bone metabolism: The role of non-coding RNAs.Maria P. Yavropoulou, John G. Yovos · 2018 · PubMed Central
- Healthy skeletal muscle aging: The role of satellite cells, somatic mutations and exerciseIrene Franco, Rodrigo Fernandez‐Gonzalo, Peter Vrtačnik, Tommy R. Lundberg, Maria Eriksson, Thomas P. Gustafsson · 2019 · International review of cytology
- RETRACTED ARTICLE: Molecular Mechanisms of Aging: The Role of Oxidative Stress and Epigenetic ModificationsК. А. Айтбаев, Ilkhom T. Murkamilov, Victor V. Fomin · 2019 · Advances in Gerontology · Retracted
- Targeting mitochondrial autophagy for anti-agingWenjun Shan, Ying Liu, Ruying Tang, Lin Li, Hongjun Yang, Longfei Lin · 2025 · Cell Death Discovery
- The Therapeutic Potential of Epigenetic Modifications in Alzheimer’s DiseaseEnric Bufill, Roser Ribosa Nogué, Rafael Blesa · 2020 · Exon Publications eBooks
- DNA Methylation of Patatin-Like Phospholipase Domain-Containing Protein 6 Gene Contributes to the Risk of Intracranial Aneurysm in MalesShengjun Zhou, Junjun Zhang, Chenhui Zhou, Fanyong Gong, Xueli Zhu, Xingqiang Pan, Jie Sun, Xiang Gao, Yi Huang · 2022 · Frontiers in Aging Neuroscience
- The genome‐wide DNA methylation profiles among neurosurgery patients with and without post‐operative deliriumTakehiko Yamanashi, Kaitlyn J. Crutchley, Nadia E. Wahba, Takaaki Nagao, Pedro S. Marra, Cade C. Akers, Eleanor J. Sullivan, Masaaki Iwata, Matthew A. Howard, Hyunkeun R. Cho et al. · 2022 · Psychiatry and Clinical Neurosciences
- Ligustilide‐loaded liposome ameliorates mitochondrial impairments and improves cognitive function via the PKA / AKAP1 signaling pathway in a mouse model of Alzheimer's diseaseQi Zhang, Xiangxiang Zhang, Bing Yang, Yan Li, Xue‐Heng Sun, Xiang Li, Ping Sui, Y Wang, Shu‐Yu Tian, Chunyan Wang · 2023 · CNS Neuroscience & Therapeutics
- METTL3 governs thymocyte development and thymic involution by regulating ferroptosisHuiru Jing, Jiayu Song, Jie Sun, Shaojun Su, Jin Jia Hu, Haojian Zhang, Yanmin Bi, Bing Wu · 2024 · Nature Aging
- Loss of chromatin structural integrity is a source of stress during agingRuofan Yu, Brenna S. McCauley, Weiwei Dang · 2020 · Human Genetics
- Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic FibroblastYoyo Chih-Yun Yu, Tony Hui, Tzu-Hao Kao, Hung‐Fu Liao, Chih-Yi Yang, Chia‐Chun Hou, Hsin-Ting Hsieh, Jen‐Yun Chang, Yi‐Tzang Tsai, Marina Pinskaya et al. · 2020 · Frontiers in Cell and Developmental Biology
- The impact of ageing on lipid-mediated regulation of adult stem cell behavior and tissue homeostasisRafael Sênos Demarco, Marie Clémot, D. Leanne Jones · 2020 · Mechanisms of Ageing and Development
- Key changes in chromatin mark mammalian epidermal differentiation and ageingChristabel Thembela Dube, Fathima Rifkhana Shah Jahan, Chin Yan Lim · 2021 · Epigenetics
- Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegansMatthieu J. Caron, Loïc Gely, Steve Garvis, Annie Adrait, Yohann Couté, Francesca Palladino, Paola Fabrizio · 2021 · Life Science Alliance
- Age-associated chromatin relaxation is enhanced in Huntington’s disease miceMyungsun Park, Byungkuk Min, Kyuheum Jeon, Sunwha Cho, Jung Sun Park, Jisun Kim, Jeha Jeon, Jinhoi Song, Seokho Kim, Sangkyun Jeong et al. · 2017 · Aging
- Molecular Basis and Emerging Strategies for Anti-aging InterventionsSuresh Rattan · 2018 · Springer eBooks
- Luteolin Decreases Fat Accumulation and Extends Lifespan in Caenorhabditis elegans via DAF-16/FOXO and NHR-49/PPAR-αFang Liu, Cao-an Hong, Shiqin Gong, Zhongyu Fan, Xin Xiao, Yi Xiao · 2025 · Journal of Agricultural and Food Chemistry
- Human iPSC-Derived Neurons as A Platform for Deciphering the Mechanisms behind Brain AgingChuan‐Chuan Chao, Po-Wen Shen, Tsai‐Yu Tzeng, Hsing‐Jien Kung, Ting‐Fen Tsai, Yu‐Hui Wong · 2021 · Biomedicines
- Body mass index mediates the association between four dietary indices and phenotypic age acceleration in adults: a cross-sectional studyJing Li, Zibo Wu, Sitong Xin, Yang Xu, Fengdan Wang, Yan Liu, Sizhe Wang, Yibo Dong, Yuangang Guo, Yu Han et al. · 2024 · Food & Function
- Decoding molecular mechanisms: brain aging and Alzheimer’s diseaseMahnoor Hayat, Rafay Ali Syed, Hammad Qaiser, Mohammad Uzair, Khalid Al-Regaiey, Roaa A. Khallaf, Lubna Abdullah Mohammed Albassam, Imdad Kaleem, Xueyi Wang, Ran Wang et al. · 2024 · Neural Regeneration Research
- Mechanisms and strategies of immunosenescence effects on non-small cell lung cancer (NSCLC) treatment: A comprehensive analysis and future directionsHuatao Zhou, Zilong Zheng, Chengming Fan, Zijing Zhou · 2025 · Seminars in Cancer Biology
- Septic Shock and the Aging Process: A Molecular ComparisonFabiano Pinheiro da Silva, Marcel Cerqueira César Machado · 2017 · Frontiers in Immunology
- Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumorsIkrame Naciri, Marthe Laisné, Laure Ferry, Morgane Bourmaud, Nikhil Gupta, Selene E. Di Carlo, Anda Huna, Nadine Martin, Lucie Peduto, David Bernard et al. · 2019 · Nucleic Acids Research
- Alu repetitive sequence CpG methylation changes in burn scarsJiraroch Meevassana, Siwat Serirodom, Piyawan Prabsattru, Papatson Boonsongserm, Supitcha Kamolratanakul, Tippawan Siritientong, Apiwat Mutirangura, Apichai Angspatt · 2021 · Burns
- Maximum reproductive lifespan correlates with CD33rSIGLEC gene number: Implications for NADPH oxidase‐derived reactive oxygen species in agingNaazneen Khan, Stuart K. Kim, Pascal Gagneux, Laura L. Dugan, Ajit P Varki · 2019 · The FASEB Journal
- Epigenetic predictors of maximum lifespan and other life history traits in mammalsChengzhang Li, Amin Haghani, Todd R. Robeck, Diego Villar, A.T. Lu, Joshua Zhang, Christopher G. Faulkes, Ha Vu, Julia Ablaeva, D.M. Adams et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity.Kriukov, Dmitrii, Khrameeva, Ekaterina E., Gladyshev, Vadim N., Dmitriev, Sergey E., Tyshkovskiy, Alexander · 2022
- Molecular Interplay of Gene Network Dynamics, Epigenetic Regulation, and Therapeutic Mapping in Cardiovascular DiseaseMd Rashedunnabi Akanda, Md Shiblee Sadik Sabuj, S M Abdus Salam, Eshrat Jahan · 2025 · Cardiovascular Drugs and Therapy
- Transcriptomic reprogramming for neuronal age reversalAlexandru M. Pleşa, Michael Shadpour, Edward S. Boyden, George McDonald Church · 2023 · Human Genetics
- RETRACTED: Ferroptosis and aerobic training in ageingNegin Kordi, Ali Saydi, Sajad Karami, Behnam Bagherzadeh-Rahmani, Emanuele Marzetti, Friedrich Jung, Brent R. Stockwell · 2024 · Clinical Hemorheology and Microcirculation · Retracted
- Immune senescence: A key player in cancer biologyYanru Yang, Linni Fan, Mingyang Li, Zhe Wang · 2024 · Seminars in Cancer Biology
- Age-related changes in histone modification in rat gastrocnemius muscleToshinori Yoshihara, Shuichi Machida, Takamasa Tsuzuki, Ryo Kakigi, Shuo-wen Chang, Takao Sugiura, Hisashi Naıto · 2019 · Experimental Gerontology
- The eroding chromatin landscape of aging stem cellsChangyou Shi, Lin Wang, Payel Sen · 2020 · Translational Medicine of Aging
- Intermittent Hypoxia Promotes Functional Neuroprotection from Retinal Ischemia in Untreated First-Generation Offspring: Proteomic Mechanistic InsightsJarrod C. Harman, Jessie J. Guidry, Jeffrey M. Gidday · 2020 · Investigative Ophthalmology & Visual Science
- Small berries as health-promoting ingredients: a review on anti-aging effects and mechanisms in Caenorhabditis elegansRong Li, Mingfang Tao, Tingting Xu, Siyi Pan, Xiaoyun Xu, Ting Wu · 2021 · Food & Function
- KDM6A Demethylase Regulates Renal Sodium Excretion and Blood PressureXiaobin Han, Leah I. Akinseye, Zhongjie Sun · 2024 · Hypertension
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- Epigenetics and AgingCarolina Soriano‐Tárraga, Jordi Jiménez-Conde, Jaume Roquer · 2019 · Springer eBooks
- Role of mismatch repair in agingJie Wen, Yangyang Wang, Minghao Yuan, Zhenting Huang, Qian Zou, Yinshuang Pu, Bin Zhao, Zhiyou Cai · 2021 · International Journal of Biological Sciences
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- METTL14 Regulates Intestine Cellular Senescence through m6A Modification of Lamin B ReceptorZizhen Zhang, Meng Xue, Jingyu Chen, Zhuo Wang, Fangyu Ju, Jiaojiao Ni, Jiawei Sun, Haoyue Wu, Huimei Zheng, Ziwei Lou et al. · 2022 · Oxidative Medicine and Cellular Longevity
- The Potential of iPSCs for the Treatment of Premature Aging DisordersClaudia Compagnucci, Enrico Bertini · 2017 · International Journal of Molecular Sciences
- Epigenetic pharmacology in aging: from mechanisms to therapies for age-related disordersHaikuan Yu, Taojin Feng, Chengcheng Zhang, Zhouguang Jiao, Wenkai Fan, Rongxian Jiang, Dewen Kong, Fubing Li · 2025 · Frontiers in Pharmacology
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- The chromatin remodeling factor Arid1a cooperates with Jun/Fos to promote osteoclastogenesis by epigenetically upregulating Siglec15 expressionYongxing Zhang, Hangxiang Sun, Fei Huang, Yang Chen, Xiying Ding, Chenhe Zhou, Yan Ting Wu, Qing Zhang, Xiao Ma, Jun Wang et al. · 2024 · Journal of Bone and Mineral Research