Epigenetic mechanisms of longevity and aging

Sen, Payel, Shah, Parisha P., Nativio, Raffaella, Berger, Shelley L.·2016·Cell

Cited by (962)

Items 401–500 of 962

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  2. Epigenetics as a mediator of genetic risk in osteoarthritis: role during development, homeostasis, aging, and disease progression
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  3. Aging-related decrease of histone methyltransferase SUV39H1 in adipose-derived stem cells enhanced SASP
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  4. Old drug, new tricks: the utility of metformin in infection and vaccination responses to influenza and SARS-CoV-2 in older adults
    Dominique E. Martin, Andreia N. Cadar, Jenna M. Bartley · 2023 · Frontiers in Aging
  5. Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence
    Anna Ungvari, Tamás Kiss, Rafał Gulej, Stefano Tarantini, Boglárka Csík, Andriy Yabluchanskiy, Péter Mukli, Anna Csiszár, Melissa L. Harris, Zoltan I. Ungvari · 2024 · GeroScience
  6. Chromatin remodeling-driven autophagy activation induces cisplatin resistance in oral squamous cell carcinoma
    Su Young Oh, Jin‐Kyung Kim, Kah Young Lee, Heon‐Jin Lee, Tae‐Geon Kwon, Jin Wook Kim, Sung‐Tak Lee, Dae-Geon Kim, So‐Young Choi, Su‐Hyung Hong · 2024 · Cell Death and Disease
  7. The tubal epigenome – An emerging target for ovarian cancer
    Hunter D. Reavis, Ronny Drapkin · 2020 · Pharmacology & Therapeutics
  8. Identification of 5-methylcytosine-related signature for predicting prognosis in ovarian cancer
    Lei Wang, Song Gao · 2021 · Biological Research
  9. When function follows form: Nuclear compartment structure and the epigenetic landscape of the aging neuron
    Johannes C. M. Schlachetzki, Tomohisa Toda, Jérôme Mertens · 2020 · Experimental Gerontology
  10. Transcriptional multiomics reveals the mechanism of seed deterioration in Nicotiana tabacum L. and Oryza sativa L.
    Jianyu An, Yihan Liu, Jiajun Han, Can He, Min Chen, Xiaobo Zhu, Weimin Hu, Wenjian Song, Jin Hu, Yajing Guan · 2022 · Journal of Advanced Research
  11. Biosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis
    Yoshiki Hayashi, Soshiro Kashio, Kazutoshi Murotomi, Shinjiro Hino, Woojin Kang, Kenji Miyado, Mitsuyoshi Nakao, Masayuki Miura, Satoru Kobayashi, Masakazu Namihira · 2022 · Scientific Reports
  12. Gut Microbiota Composition and Metabolic Potential of Long-Living People in China
    Siyuan Zhang, Ruihong Ning, Bo Zeng, Feilong Deng, Fanli Kong, Wei Guo, Jiangchao Zhao, Ying Li · 2022 · Frontiers in Aging Neuroscience
  13. The effect of growth hormone on the metabolome of follicular fluid in patients with diminished ovarian reserve
    Fan He, Fang Wang, Yang Yang, Yuan Zhi, Chengguang Sun, Heng Zou, Huijia Chen, Hongliang Yi, Shan Hu Gao, Shen Zhang et al. · 2023 · Reproductive Biology and Endocrinology
  14. Whole organism aging: Parabiosis, inflammaging, epigenetics, and peripheral and central aging clocks. The ARS of aging
    Reinald Pamplona, Mariona Jové, José Gómez, Gustavo Barja · 2023 · Experimental Gerontology
  15. Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegans
    Xinhao Hou, Mingjing Xu, Chengming Zhu, Jianing Gao, Meili Li, Xiangyang Chen, Cheng Sun, Björn Nashan, Jianye Zang, Ying Zhou et al. · 2023 · Nature Communications
  16. Implication of DNA methylation during lifestyle mediated weight loss
    Samantha Aurich, Luise Müller, Peter Louis Kovacs, Maria Keller · 2023 · Frontiers in Endocrinology
  17. DNA methylation and chromatin accessibility predict age in the domestic dog
    Kelly Jin, Brianah M. McCoy, Elisabeth A. Goldman, Viktoria Usova, Victor Tkachev, Alex Chitsazan, Anneke Dixie Kakebeen, Unity Jeffery, Kate E. Creevy, Andrea Elizabeth Wills et al. · 2024 · Aging Cell
  18. Polyphenolic Compounds: Orchestrating Intestinal Microbiota Harmony during Aging
    Quélita Cristina Pereira, Isabela Monique Fortunato, Fabrício de Sousa Oliveira, Marisa Claudia Alvarez, Tanila Wood dos Santos, Marcelo Lima Ribeiro · 2024 · Nutrients
  19. ImAge quantitates aging and rejuvenation
    Martin Alvarez-Kuglen, Kenta Ninomiya, Haodong Qin, Delany Rodriguez, Lorenzo Fiengo, Chen Farhy, Wei-Mien Hsu, Brian D. Kirk, Aaron P. Havas, Collin Kaufman et al. · 2024 · Nature Aging
  20. Small molecule-based regulation of gene expression in human astrocytes switching on and off the G-quadruplex control systems
    Vijay Kumar M J, Jérémie Mitteaux, Zi Wang, Ellery Wheeler, Nitin Tandon, Sung Yun Jung, Robert H. E. Hudson, David Monchaud, Andrey S. Tsvetkov · 2024 · Journal of Biological Chemistry
  21. Unveiling epigenetic regulation in cancer, aging, and rejuvenation with in vivo reprogramming technology
    Yuko Sogabe, Hiroshi Seno, Takuya Yamamoto, Yasuhiro Yamada · 2018 · Cancer Science
  22. Neuron-specific analysis of histone modifications with post-mortem brains
    Kagari Koshi Mano, Tatsuo Mano, Maho Morishima, Shigeo Murayama, Akira Tamaoka, Shoji Tsuji, Tatsushi Toda, Atsushi Iwata · 2020 · Scientific Reports
  23. Unravelling Cellular Mechanisms of Stem Cell Senescence: An Aid from Natural Bioactive Molecules
    Sara Cruciani, Giuseppe Garroni, Giorgio Carlo Ginesu, Angela Fadda, Carlo Ventura, Margherita Maioli · 2020 · Biology
  24. Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone
    Zhichao Zhang, Adeel Manaf, Yanjiao Li, Sonia Peña Perez, Rajikala Suganthan, John Arne Dahl, Magnar Bjørås, Arne Klungland · 2019 · Molecular Neurobiology
  25. Loss of H3K9 trimethylation leads to premature aging
    Alejandro Ocampo, Calida Mrabti, Gabriela Desdín-Micó, Gabriela Desdín-Micó, Alejandro Alonso Calleja, Alba Vílchez-Acosta, Sara Picó, Alberto Parras, Yulan Piao, Lucas Schoenfeldt et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Ultraviolet irradiation-induced inhibition of histone deacetylase 4 increases the expression of matrix metalloproteinase-1 but decreases that of type I procollagen via activating JNK in human dermal fibroblasts
    Yuri Lee, Mi Hee Shin, Min Kyoung Kim, Chi‐Hyun Park, Hye Sun Shin, Dong Hun Lee, Jin Ho Chung · 2020 · Journal of Dermatological Science
  27. RNAPII driven post-translational modifications of nucleosomal histones
    Wai Soon Chan, Amarjeet Kumar, Hidetoshi Kono · 2022 · Trends in Genetics
  28. Molecular characterization and DNA methylation analysis of carbonic anhydrase (Sp-CA) in the mud crab Scylla paramamosain: Its potential osmoregulation role under carbonate alkalinity stress
    Xiaopeng Wang, Wei Fang, Lei Liu, Yuanyuan Fu, Yueyue Zhou, Dongping Zhou, Xinlian Huang, Changkao Mu, Chunlin Wang · 2023 · Aquaculture Reports
  29. In Vitro Models of Cell Senescence: A Systematic Review on Musculoskeletal Tissues and Cells
    Francesca Veronesi, Deyanira Contartese, Laura Di Sarno, Veronica Borsari, Milena Fini, Gianluca Giavaresi · 2023 · International Journal of Molecular Sciences
  30. Bacillus Calmette-Guérin vaccination induces a trained innate immunity phenotype in adults over 50 years of age: A randomized trial in Guinea-Bissau
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  31. Downregulation of MLF1 safeguards cardiomyocytes against senescence-associated chromatin opening
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  32. Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue
    Lore Becker, Melanie Schmitt Nogueira, Caroline Klima, Martin Hrabě de Angelis, Shahaf Peleg · 2018 · Scientific Reports
  33. The "dark matter" of DNA and the regulation of bone metabolism: The role of non-coding RNAs.
    Maria P. Yavropoulou, John G. Yovos · 2018 · PubMed Central
  34. Healthy skeletal muscle aging: The role of satellite cells, somatic mutations and exercise
    Irene Franco, Rodrigo Fernandez‐Gonzalo, Peter Vrtačnik, Tommy R. Lundberg, Maria Eriksson, Thomas P. Gustafsson · 2019 · International review of cytology
  35. RETRACTED ARTICLE: Molecular Mechanisms of Aging: The Role of Oxidative Stress and Epigenetic Modifications
    К. А. Айтбаев, Ilkhom T. Murkamilov, Victor V. Fomin · 2019 · Advances in Gerontology · Retracted
  36. Targeting mitochondrial autophagy for anti-aging
    Wenjun Shan, Ying Liu, Ruying Tang, Lin Li, Hongjun Yang, Longfei Lin · 2025 · Cell Death Discovery
  37. The Therapeutic Potential of Epigenetic Modifications in Alzheimer’s Disease
    Enric Bufill, Roser Ribosa Nogué, Rafael Blesa · 2020 · Exon Publications eBooks
  38. DNA Methylation of Patatin-Like Phospholipase Domain-Containing Protein 6 Gene Contributes to the Risk of Intracranial Aneurysm in Males
    Shengjun Zhou, Junjun Zhang, Chenhui Zhou, Fanyong Gong, Xueli Zhu, Xingqiang Pan, Jie Sun, Xiang Gao, Yi Huang · 2022 · Frontiers in Aging Neuroscience
  39. The genome‐wide DNA methylation profiles among neurosurgery patients with and without post‐operative delirium
    Takehiko Yamanashi, Kaitlyn J. Crutchley, Nadia E. Wahba, Takaaki Nagao, Pedro S. Marra, Cade C. Akers, Eleanor J. Sullivan, Masaaki Iwata, Matthew A. Howard, Hyunkeun R. Cho et al. · 2022 · Psychiatry and Clinical Neurosciences
  40. Ligustilide‐loaded liposome ameliorates mitochondrial impairments and improves cognitive function via the PKA / AKAP1 signaling pathway in a mouse model of Alzheimer's disease
    Qi Zhang, Xiangxiang Zhang, Bing Yang, Yan Li, Xue‐Heng Sun, Xiang Li, Ping Sui, Y Wang, Shu‐Yu Tian, Chunyan Wang · 2023 · CNS Neuroscience & Therapeutics
  41. METTL3 governs thymocyte development and thymic involution by regulating ferroptosis
    Huiru Jing, Jiayu Song, Jie Sun, Shaojun Su, Jin Jia Hu, Haojian Zhang, Yanmin Bi, Bing Wu · 2024 · Nature Aging
  42. Loss of chromatin structural integrity is a source of stress during aging
    Ruofan Yu, Brenna S. McCauley, Weiwei Dang · 2020 · Human Genetics
  43. Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast
    Yoyo Chih-Yun Yu, Tony Hui, Tzu-Hao Kao, Hung‐Fu Liao, Chih-Yi Yang, Chia‐Chun Hou, Hsin-Ting Hsieh, Jen‐Yun Chang, Yi‐Tzang Tsai, Marina Pinskaya et al. · 2020 · Frontiers in Cell and Developmental Biology
  44. The impact of ageing on lipid-mediated regulation of adult stem cell behavior and tissue homeostasis
    Rafael Sênos Demarco, Marie Clémot, D. Leanne Jones · 2020 · Mechanisms of Ageing and Development
  45. Key changes in chromatin mark mammalian epidermal differentiation and ageing
    Christabel Thembela Dube, Fathima Rifkhana Shah Jahan, Chin Yan Lim · 2021 · Epigenetics
  46. Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans
    Matthieu J. Caron, Loïc Gely, Steve Garvis, Annie Adrait, Yohann Couté, Francesca Palladino, Paola Fabrizio · 2021 · Life Science Alliance
  47. Age-associated chromatin relaxation is enhanced in Huntington’s disease mice
    Myungsun Park, Byungkuk Min, Kyuheum Jeon, Sunwha Cho, Jung Sun Park, Jisun Kim, Jeha Jeon, Jinhoi Song, Seokho Kim, Sangkyun Jeong et al. · 2017 · Aging
  48. Molecular Basis and Emerging Strategies for Anti-aging Interventions
    Suresh Rattan · 2018 · Springer eBooks
  49. Luteolin Decreases Fat Accumulation and Extends Lifespan in Caenorhabditis elegans via DAF-16/FOXO and NHR-49/PPAR-α
    Fang Liu, Cao-an Hong, Shiqin Gong, Zhongyu Fan, Xin Xiao, Yi Xiao · 2025 · Journal of Agricultural and Food Chemistry
  50. Human iPSC-Derived Neurons as A Platform for Deciphering the Mechanisms behind Brain Aging
    Chuan‐Chuan Chao, Po-Wen Shen, Tsai‐Yu Tzeng, Hsing‐Jien Kung, Ting‐Fen Tsai, Yu‐Hui Wong · 2021 · Biomedicines
  51. Body mass index mediates the association between four dietary indices and phenotypic age acceleration in adults: a cross-sectional study
    Jing Li, Zibo Wu, Sitong Xin, Yang Xu, Fengdan Wang, Yan Liu, Sizhe Wang, Yibo Dong, Yuangang Guo, Yu Han et al. · 2024 · Food & Function
  52. Decoding molecular mechanisms: brain aging and Alzheimer’s disease
    Mahnoor Hayat, Rafay Ali Syed, Hammad Qaiser, Mohammad Uzair, Khalid Al-Regaiey, Roaa A. Khallaf, Lubna Abdullah Mohammed Albassam, Imdad Kaleem, Xueyi Wang, Ran Wang et al. · 2024 · Neural Regeneration Research
  53. Mechanisms and strategies of immunosenescence effects on non-small cell lung cancer (NSCLC) treatment: A comprehensive analysis and future directions
    Huatao Zhou, Zilong Zheng, Chengming Fan, Zijing Zhou · 2025 · Seminars in Cancer Biology
  54. Septic Shock and the Aging Process: A Molecular Comparison
    Fabiano Pinheiro da Silva, Marcel Cerqueira César Machado · 2017 · Frontiers in Immunology
  55. Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors
    Ikrame Naciri, Marthe Laisné, Laure Ferry, Morgane Bourmaud, Nikhil Gupta, Selene E. Di Carlo, Anda Huna, Nadine Martin, Lucie Peduto, David Bernard et al. · 2019 · Nucleic Acids Research
  56. Alu repetitive sequence CpG methylation changes in burn scars
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  57. Maximum reproductive lifespan correlates with CD33rSIGLEC gene number: Implications for NADPH oxidase‐derived reactive oxygen species in aging
    Naazneen Khan, Stuart K. Kim, Pascal Gagneux, Laura L. Dugan, Ajit P Varki · 2019 · The FASEB Journal
  58. Epigenetic predictors of maximum lifespan and other life history traits in mammals
    Chengzhang Li, Amin Haghani, Todd R. Robeck, Diego Villar, A.T. Lu, Joshua Zhang, Christopher G. Faulkes, Ha Vu, Julia Ablaeva, D.M. Adams et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity.
    Kriukov, Dmitrii, Khrameeva, Ekaterina E., Gladyshev, Vadim N., Dmitriev, Sergey E., Tyshkovskiy, Alexander · 2022
  60. Molecular Interplay of Gene Network Dynamics, Epigenetic Regulation, and Therapeutic Mapping in Cardiovascular Disease
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  61. Transcriptomic reprogramming for neuronal age reversal
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  62. RETRACTED: Ferroptosis and aerobic training in ageing
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  63. Immune senescence: A key player in cancer biology
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  64. Age-related changes in histone modification in rat gastrocnemius muscle
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  65. The eroding chromatin landscape of aging stem cells
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  66. Intermittent Hypoxia Promotes Functional Neuroprotection from Retinal Ischemia in Untreated First-Generation Offspring: Proteomic Mechanistic Insights
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  67. Small berries as health-promoting ingredients: a review on anti-aging effects and mechanisms in Caenorhabditis elegans
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  68. KDM6A Demethylase Regulates Renal Sodium Excretion and Blood Pressure
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  69. Aging Epigenetics
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  70. Metallome evolution in ageingC. elegansand a copper stable isotope perspective
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  71. Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse
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  73. Breaking the Glass Ceiling
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  74. How to measure and model cardiovascular aging
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  77. Neuronal Dot1l Activity Acts as a Mitochondrial Gene-Repressor Associated with Human Brain Aging via H3K79 Hypermethylation
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  81. MSC-derived exosomes alleviate oxidative stress-induced lysosomal membrane permeabilization damage in degenerated nucleus pulposus cells via promoting m6A demethylation of Nrf2
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  82. Epigenetics and Aging
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  83. Role of mismatch repair in aging
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  84. Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways
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  90. Senescence‐induced immunophenotype, gene expression and electrophysiology changes in human amniocytes
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  93. Footprints in the Sand: Deep Taxonomic Comparisons in Vertebrate Genomics to Unveil the Genetic Programs of Human Longevity
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  94. METTL14 Regulates Intestine Cellular Senescence through m6A Modification of Lamin B Receptor
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  95. The Potential of iPSCs for the Treatment of Premature Aging Disorders
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  96. Epigenetic pharmacology in aging: from mechanisms to therapies for age-related disorders
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  97. Hypermethylation in H3K9me3 regions characterizes the centenarian methylomes in healthy aging
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  98. Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae
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  99. Unraveling lipid and inflammation interplay in cancer, aging and infection for novel theranostic approaches
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  100. The chromatin remodeling factor Arid1a cooperates with Jun/Fos to promote osteoclastogenesis by epigenetically upregulating Siglec15 expression
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