Epigenetic mechanisms of longevity and aging

Sen, Payel, Shah, Parisha P., Nativio, Raffaella, Berger, Shelley L.·2016·Cell

Cited by (962)

Items 701–800 of 962

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    Ruiyan Zhang, Linlin Liu, Xiaoman Shi, Yanming Ren · 2025 · Genes & Diseases
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    Zhongxiao Lin, Jianyu Xiong, Fuyuan Zhang, Hao Zhang, Menglin Zhu, Caiyu Li, Rong Fu, Zhongyi Zhang, Qinwen Hu, Jie Liang et al. · 2025 · Molecular Therapy
  3. SREBP1-mediated lipogenesis promotes dedifferentiation and senescence of vascular smooth muscle cells through epigenetic remodeling
    Bowen Li, Kaixiang Zhou, Anan Yin, Y F Liu, Xichen Wang, Yujia Cui, Fangfang Liu, Qiurong Liu, Hongjing Zheng, Zhiqiang Mu et al. · 2025 · Nature Communications
  4. Bidirectional associations between metabolic syndrome and epigenetic age acceleration: A 20-year longitudinal study in midlife adults
    Hye-Young Park, Kyeezu Kim · 2025 · Experimental Gerontology
  5. Molecular underpinnings of induced degenerative heterogeneity in the retinal pigment epithelium
    Krishna Kumar Singh, Yang Oh Jin, Ming-Wen Hu, Isabella Palazzo, Marisol Cano, Thanh Hoang, Imran Ahmed Bhutto, Shusheng Wang, Debasish Sinha, Seth Blackshaw et al. · 2026 · Proceedings of the National Academy of Sciences
  6. Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy
    Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu · 2026 · MedComm – Oncology
  7. Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling
    Degisew Yinur Mengistu, Biniam Moges Eskeziyaw · 2026 · Brain and Behavior
  8. Histone modifications in biological age determination: mechanisms, biomarkers, and therapeutic perspectives
    Anjali Tripathi, Garima Sharma, Vinay Kumar Pandey, Sarvesh Rustagi, Ashish Ranjan Sharma, Meenakshi Jha, Abhijit Debnath, Jomon George Joy, Jin‐Chul Kim, Abhimanyu Kumar Jha · 2026 · GeroScience
  9. Oridonin as a novel KDM5C inhibitor alleviates clonal hematopoiesis-induced cardiac aging via H3K4me3-dependent SASP suppression
    Xingling Chen, Qianqiang Zhao, Linhuang Chen, Shengrong Lin, Bin Mai, Xingling He, Xiaojiao Zhang, Jiahui Chen, Sijing Li, Ziru Li et al. · 2026 · Acta Pharmaceutica Sinica B
  10. Cell‐Type‐Specific Causal Inference Unveils Novel Targets for Parkinson's Disease
    Si‐Chun Gu, Qiao Yang Sun, Wen Zhang, Chang‐Yi Shen, Hang Su, Fang Xie, Can‐Xing Yuan, Zhidong Zhou, Eng‐King Tan, Qing Ye · 2026 · Movement Disorders
  11. Non-canonical regulated cell death and epigenetic mechanisms in the nervous system
    Adalberto Merighi, Claudia Castagna, Marco Sbriz, Laura Lossi · 2026 · Frontiers in Cell Death
  12. The role and mechanisms of methylation modifications in the development and progression of hypertension
    Hongxia Niu, Yilei Kong, Zehua Liu, Zhiting Yang, Yang Hu, Zhu Aisong · 2026 · Ageing Research Reviews
  13. Nutrition as a systems regulator of brain aging trajectories
    Ludmila Müller, Svetlana Di Benedetto, Viktor Müller · 2026 · Frontiers in Molecular Neuroscience
  14. Age-associated epigenetic drift trajectory and cross-national disparities in accelerated aging in domestic dogs
    Subin Jang, Seongjun Kim, Dayeon Kang, Chae‐Yeon Hong, Eun‐Yeong Bok, Sung‐Lim Lee, Yong‐Ho Choe, Jaemin Kim · 2026 · Proceedings of the National Academy of Sciences
  15. Oocyte Aging as a Systems-Level Failure of Cellular Quality Control Networks: Insights from Comparative Biology
    Magda Sochaczewska, Wacław Tworzydlo · 2026 · Biology
  16. Population Epigenomics and Aging
    Carsten Carlberg, Ferdinand Molnár · 2018 · Springer eBooks
  17. Epigenetic-Processes Driven Disorders and Therapeutics
    Sravya Thumoju, Vasavi Mohan · 2018 · Elsevier eBooks
  18. Unraveling the syndrome of age-associated diseases: Common pathways and novel therapeutic strategies
    Roland H. Mertelsmann, Laura Eva Faletti, Katja Zirlik · 2019 · Journal of Science Humanities and Arts - JOSHA
  19. Cellular Senescence in Aging Mucosal Tissues Is Accentuated by Periodontitis
    Jeffrey L. Ebersole, Octavio A. González · 2020 · Springer eBooks
  20. Coenzyme Q and Aging in the Fruit Fly Drosophila melanogaster
    Daniel J.M. Fernández‐Ayala, Alberto Sanz · 2020 · Springer eBooks
  21. Aging and Cancer Prognosis
    Arvin Haj‐Mirzaian, Khashayar Afshari, Amir Hossein Abdolghaffari · 2020 · Springer eBooks
  22. Epigenetics and Aging
    Carolina Soriano‐Tárraga, Jordi Jiménez-Conde, Jaume Roquer · 2018 · Springer eBooks
  23. Cytokine Polymorphisms, Immunosenescence, and Neurodegeneration
    Owen A. Ross, Ronald L. Walton, Kelly M. Hinkle, Neill Graff-Radford, Irene Maeve Rea · 2019 · Springer eBooks
  24. The Biology of Death
    Gary C. Howard · 2021
  25. Epigenetic processes–driven disorders and therapeutics
    Vasavi Mohan, Sravya Thumoju, Mohammed Khaliq Mohiuddin · 2023 · Elsevier eBooks
  26. Aging and disease
    Andrea Fuso · 2023 · Elsevier eBooks
  27. Opposite and Differently Altered Postmortem Changes in H3 and H3K9me3 Patterns in the Rat Frontal Cortex and Hippocampus
    Karolina Dulka, Noémi Lajkó, Kálmán Nacsa, Károly Gulya · 2024 · Epigenomes
  28. Pathogenesis of diabetic atherosclerotic cardiovascular disease
    Angelo Avogaro · 2024 · Elsevier eBooks
  29. Linking Aging to Cancer: The Role of Chromatin Biology
    Laura Corveleyn, Payel Sen, Peter D. Adams, Simone Sidoli · 2024 · The Journals of Gerontology Series A
  30. Transcriptional Regulation in the Control of Aging and Longevity
    Olga Y. Rybina, ELENA G. PASYUKOVA · 2023 · Advances in Gerontology
  31. DNA Damage, Transposable Element Expression and Their Associated Factors in Aging
    Temesgen Mitiku, Betelhem Abebe, Nega Birhane, Birhan Getie · 2024 · Biochemistry and Molecular Biology
  32. Studying Cellular Senescence Using the Model Organism Drosophila melanogaster
    Xanthippi P. Louka, Sentiljana Gumeni, Ioannis P. Trougakos · 2025 · Methods in molecular biology
  33. Epigenetik Mekanizmaların Besinlerin Biyoaktif Bileşenleri ile İlişkisi
    Deniz Mıhçıoğlu · 2019 · Journal of Nutrition and Dietetics
  34. Epigenetics in Exercise
    Moran S. Saghiv, Michael S. Sagiv · 2020 · Springer eBooks
  35. Epigenetics, aging and early life
    Radhika Dhingra, Jamaji C. Nwanaji‐Enwerem, Allison E. Aiello, Francie Sentilles, B. G. King, Cavin K Ward-Caviness · 2020 · Elsevier eBooks
  36. Aging and Senescence
    Gary C. Howard · 2021 · Oxford University Press eBooks
  37. Stem Cell Quiescence versus Senescence: The Key for Healthy Aging
    Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya · 2021 · The Indonesian Biomedical Journal
  38. Epigenetic Modifications Involved in Ageing Process: The Role of Histone Methylation of SET-Domain
    Pambu Lelo Aaron, Zakuani Luzinga Nadege, Fabrice Ndayisenga, Gédéon Ngiala Bongo · 2022 · Biochemistry
  39. Discovery of a Highly Selective Cell‐Active Inhibitor of the Histone Lysine Demethylases KDM2/7
    Philip A. Gerken, Jamie R. Wolstenhulme, Anthony Tumber, Stephanie B. Hatch, Yijia Zhang, Susanne Müller, Shane A. Chandler, Barbara Mair, Fengling Li, Sebastian M. B. Nijman et al. · 2017 · Angewandte Chemie
  40. Aging and Disease
    Andrea Fuso · 2018 · Elsevier eBooks
  41. Nutrigenomics of Aging
    Nelma M. Palminha, Sara A. Hashish, Eman Rabie, S. Saber · 2022 · Nutritional neurosciences
  42. Mammalian Resilience Revealed by a Comparison of Human Diseases and Mouse Models Associated With DNA Helicase Deficiencies
    Masaoki Kohzaki · 2022 · Frontiers in Molecular Biosciences
  43. Epigenome editing in mice: The dawn of the reverse epigenetics era
    Izuho Hatada, Sumiyo Morita, Takuro Horii · 2022 · Gene and Genome Editing
  44. Basic pathways and targets for anti-aging intervention
    Mercedes Cano, Yiu To Yeung, Mario F. Muñoz, Antonio Ayala, Angélica Guerrero‐Castilla, Sandro Argüelles · 2023 · Elsevier eBooks
  45. Investigating the Causes of Cellular Aging and Uncovering the Novel Vision of Anti-aging Therapeutics
    Ashwin Prabahar A · 2023 · Journal of Clinical and Medical Research
  46. Association of Self Perception of Pre-Mature Ageing and Human Constitution (Prakriti) - A Cross-Sectional Study
    Rakesh Roushan · 2022 · Epidemiology International
  47. DECODER: A probabilistic approach to integrate big data reveals mitochondrial Complex I as a potential therapeutic target for Alzheimer’s disease
    Safiye Çelik, Joshua C. Russell, Cezar Rangel Pestana, Ting-I Lee, Shubhabrata Mukherjee, Paul K. Crane, Christopher Dirk Keene, Jennifer F. Bobb, Matt R. Kaeberlein, Su‐In Lee · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  48. DNA methylation change in neurotrophic genes with aging and delirium evidenced from three independent cohorts
    Taku Saito, Patricia Braun, Sophia Daniel, Sydney S. Jellison, Mandy M. Hellman, Eri Shinozaki, Sangil Lee, Hyunkeun R. Cho, Aihide Yoshino, Hiroyuki Toda et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  49. Molecular Mechanisms Underlying Cardiometabolic Disease in Aging
    Víctor Fanjul · 2019
  50. Integrative Epigenomic and Transcriptomic Analysis Reveals Robust Metabolic Switching in the Brain During Intermittent Fasting
    Gavin Yong-Quan Ng, Dominic Paul Lee Kok Sheng, Sung Wook Kang, David Yang‐Wei Fann, Joonki Kim, Asfa Alli Shaik, Yoon Suk Cho, Jihoon Han, Jae Hoon Sul, Vardan T. Karamyan et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  51. Single-cell epigenomic tracing of lifelong endothelial cell plasticity across mouse organs
    Xianhong Yu, Yaxi Liu, Xiaoge Liu, Haiqing Xiong, Aibin He · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  52. Análise longitudinal das condições de vida e saúde de idosos com histórico de câncer: Estudo Saúde, Bem-Estar e Envelhecimento
    Tatiana Massaroli de [UNESP] Melo · 2021
  53. Epigenetics of post-operative delirium: A genome-wide DNA methylation study of neurosurgery patients
    Takehiko Yamanashi, Kaitlyn J. Crutchley, Nadia E. Wahba, Takaaki Nagao, Pedro S. Marra, Cade C. Akers, Eleanor J. Sullivan, Masaaki Iwata, Matthew A. Howard, Hyunkeun R. Cho et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  54. On the Origin of Aging by Means of Natural Selection
    Richard F. Walker · 2023 · Qeios
  55. Epigenetic Modifications and Their Relevance in the Normal and Pathological Brain
    Laura Lossi, Adalberto Merighi · 2023 · Preprints.org
  56. IFT20 and WWTR1 govern bone homeostasis via synchronously regulating the expression and stability of TβRII in osteoblast lineage cells
    Shuying Yang, Yang Li, Shuting Yang · 2024 · Research Square
  57. Epigenetic Reprogramming of Aging: Reversing the Clock for Regenerative Medicine
    Mohammad Odah · 2024 · Preprints.org
  58. Modulating DNA Polα Enhances Cell Reprogramming Across Species
    Rajesh Ranjan, Binbin Ma, Ryan J. Gleason, Yijun Liao, Yingshan Bi, Brendon E. M. Davis, Guanghui Yang, Maggie Clark, Vikrant Mahajan, Madison Condon et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  59. BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis
    Júlia Bonjoch, Paloma Solá, Óscar Reina, Thomas Mortimer, Yekaterina A. Miroshnikova, Sara A. Wickström, Camille Stephan‐Otto Attolini, Laura Álvarez, Salvador Aznar Benitah, Guiomar Solanas · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  60. The aging transcriptome: a condition-dependent response to a deteriorating soma
    Zeeshan Ali Syed, Martin Brengdahl, Vinesh Naresh Shenoi, Avani Mital, Christopher M. Kimber, Helen Ekman, Claudio Mirabello, Malin Larsson, David Berger, Urban Friberg · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  61. Measuring Immunological Age: From T cell Repertoires to Populations
    Elena N. Naumova, Yuri N. Naumov, Jack Gorski · 2017 · Springer eBooks
  62. Cytokine Polymorphisms, Immunosenescence, and Neurodegeneration
    Owen A. Ross, Ronald L. Walton, Kelly M. Hinkle, Neill R. Graff‐Radford, Irene Maeve Rea · 2017 · Springer eBooks
  63. CHARACTERISTICS OF GENOME REGULATORY ELEMENTS
    D.A. Oleynik, E.Yu Rodina · 2017 · International Journal of Applied and Fundamental Research (Международный журнал прикладных и фундаментальных исследований)
  64. Epigenome comparisons reveal linkage between gene expression and postnatal remodeling of chromatin domain topology
    Bruce H. Howard, Tazuko H. Hirai, Valya R. RUSSANOVA · 2018 · PLoS ONE
  65. Epigenetic heterogeneity revealed through single-cell DNA methylation sequencing
    Zhao Hui · 2018 · cIRcle (University of British Columbia)
  66. Epigenetic Programming of Human Disease and Aging
    Alexander M. Vaiserman, Alexander K. Koliada, Oleh V. Lushchak · 2018 · Elsevier eBooks
  67. The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature Aging
    Dido Carrero, Carlos López-Otı́n · 2018 · Springer eBooks
  68. Assessing the Effect of Epigenetic Dysregulation on Oncogenesis and Immunocompetence in a Mouse Model
    Joseph Rosenthal · 2018 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  69. Temporal inhibition of autophagy reveals segmental reversal of aging with increased cancer risk
    Liam D. Cassidy, Andrew R. J. Young, Chris Young, Elizabeth J. Soilleux, Edward Fielder, Bettina M. Weigand, Rebecca J. Brais, Kimberley A. Wiggins, Murray C.H. Clarke, Diana Jurk et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  70. Modifiability of Longevity and Quality-of-Life Predictors of Older Adults
    Jessica Stephens, Mathew Fiedler, Michelle Lidell, Robert J. Gatchel · 2018 · Handbooks in health, work, and disability
  71. Epigenomic reprogramming of caloric restriction on aging
    S. Ribarič · 2019 · Nutritional Epigenomics
  72. Introductory Chapter: Epigenetics in Summary
    Rosaria Meccariello · 2019 · IntechOpen eBooks
  73. Epigenetics and imprinting in assisted reproduction
    Diego Marín, Emre U Seli · 2020 · Elsevier eBooks
  74. Epigenetics of the Aging Musculoskeletal System
    Boris Slobodin · 2020 · Springer eBooks
  75. Simultaneous transcriptome and methylome profiles of single mouse oocytes provide novel insights on maturation and aging
    Qian Yan, Qin Cao, Jinyue Liao, Chun Shui Luk, Ashley Hoi Ching Suen, Annie Wing-Tung Lee, Ting Hei Thomas Chan, Judy Kin Wing Ng, Nelson L.S. Tang, Hoi Sze Chung et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  76. RNA and aging
    Milan Mušo · 2020 · Elsevier eBooks
  77. Hydroxytyrosol, olive oil, and use in aging
    Mercedes Cano, Mario Muñoz, Antonio Ayala, Rafael Medina-Guzman, Sandro Argüelles · 2021 · Elsevier eBooks
  78. Aging Biomarkers-Disorders Characterized by Premature Aging
    Deeraja Manvi Gatta, Sai Sravani Botcha · 2021 · Biomarkers
  79. Targeting hepatic stellate cells to prevent or reverse liver fibrosis
    Mengfan Zhang · 2020
  80. Histone Demethylase UTX Compromises Articular Chondrocyte Anabolism and Aggravates Osteoarthritic Degeneration
    Wei‐Shiung Lian, Re‐Wen Wu, Jih‐Yang Ko, Yushan Chen, Shao-Yu Wang, Chun-Ping Yu, Holger Jahr, Fengsheng Wang · 2021 · Research Square
  81. Aging-associated changes in metabolic regulation of epigenetic modifications and gene expression
    Poonam Bheda · 2021 · Elsevier eBooks
  82. Death in Life
    Gary C. Howard · 2021 · Oxford University Press eBooks
  83. Genetics of Life and Death
    Gary C. Howard · 2021 · Oxford University Press eBooks
  84. Death Is More than Dying
    Gary C. Howard · 2021 · Oxford University Press eBooks
  85. H3K4me3 enrichment defines neuronal age, while a youthful H3K27ac signature is recapitulated in aged neurons
    Katherine A. Giles, Andrew J. Phipps, Jake M. Cashion, Shannon N. Huskins, Tim R. Mercer, Mark D. Robinson, Adele Woodhouse, Phillippa C. Taberlay · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  86. Bioethics
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  87. Dying
    Gary C. Howard · 2021 · Oxford University Press eBooks
  88. Cell biologist’s perspective: Frontiers in Development of PROTAC-HDAC degraders.
    Alex Sobko · 2021
  89. Functional genomics of ageing: implications of chromatin landscape and beyond
    Antonis Kirmizis · 2022 · Briefings in Functional Genomics
  90. Phenotype
    Nancy B. Y. Tsui, Johnson Y.N. Lau · 2021 · Springer eBooks
  91. Faculty Opinions recommendation of Reprogramming to recover youthful epigenetic information and restore vision.
    Malcolm Maden · 2021 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  92. The annoying flaws of gerontological research
    Magomed Khaidakov, Valeria Troshina, Dmitry Menglet, Yu N Yusef, Alexander Plotkin · 2022 · Drug Metabolism Reviews
  93. Aging Principles and Perspectives for Intervention
    Suresh I. S. Rattan · 2018 · Springer eBooks
  94. Epigenomic and transcriptomic analysis of developing, adult and aging brain: mechanisms of brain folding, neuronal function and finding novel therapy for dementia
    M. Sadman Sakib · 2021
  95. Faculty Opinions recommendation of HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity.
    Seung‐Jae Lee, Yoonji Jung · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  96. Age-dependent transcriptional and epigenetic alterations in mouse hepatocytes
    Sharma, Ankur · 2021
  97. Effect of ageing on biochemical, genetic and epigenetic stability during seed storage
    Michela Pirredda · 2021
  98. Faculty Opinions recommendation of Reprogramming to recover youthful epigenetic information and restore vision.
    Pinghua Liu · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  99. Faculty Opinions recommendation of Cytoplasmic chromatin triggers inflammation in senescence and cancer.
    Jing‐Dong J. Han · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  100. Measuring Immunological Age: From T Cell Repertoires to Populations
    Elena N. Naumova, Yuri N. Naumov, Jack Gorski · 2019 · Springer eBooks