Epigenetic mechanisms of longevity and aging
Sen, Payel, Shah, Parisha P., Nativio, Raffaella, Berger, Shelley L.·2016·Cell
Cited by (962)
Items 701–800 of 962
- Obesity accelerates aging: Mechanisms and therapeutic implicationsRuiyan Zhang, Linlin Liu, Xiaoman Shi, Yanming Ren · 2025 · Genes & Diseases
- Targeting KAT8 alleviates vascular senescence by modulating the INHBA/TGF-β pathwayZhongxiao Lin, Jianyu Xiong, Fuyuan Zhang, Hao Zhang, Menglin Zhu, Caiyu Li, Rong Fu, Zhongyi Zhang, Qinwen Hu, Jie Liang et al. · 2025 · Molecular Therapy
- SREBP1-mediated lipogenesis promotes dedifferentiation and senescence of vascular smooth muscle cells through epigenetic remodelingBowen Li, Kaixiang Zhou, Anan Yin, Y F Liu, Xichen Wang, Yujia Cui, Fangfang Liu, Qiurong Liu, Hongjing Zheng, Zhiqiang Mu et al. · 2025 · Nature Communications
- Bidirectional associations between metabolic syndrome and epigenetic age acceleration: A 20-year longitudinal study in midlife adultsHye-Young Park, Kyeezu Kim · 2025 · Experimental Gerontology
- Molecular underpinnings of induced degenerative heterogeneity in the retinal pigment epitheliumKrishna Kumar Singh, Yang Oh Jin, Ming-Wen Hu, Isabella Palazzo, Marisol Cano, Thanh Hoang, Imran Ahmed Bhutto, Shusheng Wang, Debasish Sinha, Seth Blackshaw et al. · 2026 · Proceedings of the National Academy of Sciences
- Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and TherapyQi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu · 2026 · MedComm – Oncology
- Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin RemodelingDegisew Yinur Mengistu, Biniam Moges Eskeziyaw · 2026 · Brain and Behavior
- Histone modifications in biological age determination: mechanisms, biomarkers, and therapeutic perspectivesAnjali Tripathi, Garima Sharma, Vinay Kumar Pandey, Sarvesh Rustagi, Ashish Ranjan Sharma, Meenakshi Jha, Abhijit Debnath, Jomon George Joy, Jin‐Chul Kim, Abhimanyu Kumar Jha · 2026 · GeroScience
- Oridonin as a novel KDM5C inhibitor alleviates clonal hematopoiesis-induced cardiac aging via H3K4me3-dependent SASP suppressionXingling Chen, Qianqiang Zhao, Linhuang Chen, Shengrong Lin, Bin Mai, Xingling He, Xiaojiao Zhang, Jiahui Chen, Sijing Li, Ziru Li et al. · 2026 · Acta Pharmaceutica Sinica B
- Cell‐Type‐Specific Causal Inference Unveils Novel Targets for Parkinson's DiseaseSi‐Chun Gu, Qiao Yang Sun, Wen Zhang, Chang‐Yi Shen, Hang Su, Fang Xie, Can‐Xing Yuan, Zhidong Zhou, Eng‐King Tan, Qing Ye · 2026 · Movement Disorders
- Non-canonical regulated cell death and epigenetic mechanisms in the nervous systemAdalberto Merighi, Claudia Castagna, Marco Sbriz, Laura Lossi · 2026 · Frontiers in Cell Death
- The role and mechanisms of methylation modifications in the development and progression of hypertensionHongxia Niu, Yilei Kong, Zehua Liu, Zhiting Yang, Yang Hu, Zhu Aisong · 2026 · Ageing Research Reviews
- Nutrition as a systems regulator of brain aging trajectoriesLudmila Müller, Svetlana Di Benedetto, Viktor Müller · 2026 · Frontiers in Molecular Neuroscience
- Age-associated epigenetic drift trajectory and cross-national disparities in accelerated aging in domestic dogsSubin Jang, Seongjun Kim, Dayeon Kang, Chae‐Yeon Hong, Eun‐Yeong Bok, Sung‐Lim Lee, Yong‐Ho Choe, Jaemin Kim · 2026 · Proceedings of the National Academy of Sciences
- Oocyte Aging as a Systems-Level Failure of Cellular Quality Control Networks: Insights from Comparative BiologyMagda Sochaczewska, Wacław Tworzydlo · 2026 · Biology
- Population Epigenomics and AgingCarsten Carlberg, Ferdinand Molnár · 2018 · Springer eBooks
- Epigenetic-Processes Driven Disorders and TherapeuticsSravya Thumoju, Vasavi Mohan · 2018 · Elsevier eBooks
- Unraveling the syndrome of age-associated diseases: Common pathways and novel therapeutic strategiesRoland H. Mertelsmann, Laura Eva Faletti, Katja Zirlik · 2019 · Journal of Science Humanities and Arts - JOSHA
- Cellular Senescence in Aging Mucosal Tissues Is Accentuated by PeriodontitisJeffrey L. Ebersole, Octavio A. González · 2020 · Springer eBooks
- Coenzyme Q and Aging in the Fruit Fly Drosophila melanogasterDaniel J.M. Fernández‐Ayala, Alberto Sanz · 2020 · Springer eBooks
- Aging and Cancer PrognosisArvin Haj‐Mirzaian, Khashayar Afshari, Amir Hossein Abdolghaffari · 2020 · Springer eBooks
- Epigenetics and AgingCarolina Soriano‐Tárraga, Jordi Jiménez-Conde, Jaume Roquer · 2018 · Springer eBooks
- Cytokine Polymorphisms, Immunosenescence, and NeurodegenerationOwen A. Ross, Ronald L. Walton, Kelly M. Hinkle, Neill Graff-Radford, Irene Maeve Rea · 2019 · Springer eBooks
- The Biology of DeathGary C. Howard · 2021
- Epigenetic processes–driven disorders and therapeuticsVasavi Mohan, Sravya Thumoju, Mohammed Khaliq Mohiuddin · 2023 · Elsevier eBooks
- Aging and diseaseAndrea Fuso · 2023 · Elsevier eBooks
- Opposite and Differently Altered Postmortem Changes in H3 and H3K9me3 Patterns in the Rat Frontal Cortex and HippocampusKarolina Dulka, Noémi Lajkó, Kálmán Nacsa, Károly Gulya · 2024 · Epigenomes
- Pathogenesis of diabetic atherosclerotic cardiovascular diseaseAngelo Avogaro · 2024 · Elsevier eBooks
- Linking Aging to Cancer: The Role of Chromatin BiologyLaura Corveleyn, Payel Sen, Peter D. Adams, Simone Sidoli · 2024 · The Journals of Gerontology Series A
- Transcriptional Regulation in the Control of Aging and LongevityOlga Y. Rybina, ELENA G. PASYUKOVA · 2023 · Advances in Gerontology
- DNA Damage, Transposable Element Expression and Their Associated Factors in AgingTemesgen Mitiku, Betelhem Abebe, Nega Birhane, Birhan Getie · 2024 · Biochemistry and Molecular Biology
- Studying Cellular Senescence Using the Model Organism Drosophila melanogasterXanthippi P. Louka, Sentiljana Gumeni, Ioannis P. Trougakos · 2025 · Methods in molecular biology
- Epigenetik Mekanizmaların Besinlerin Biyoaktif Bileşenleri ile İlişkisiDeniz Mıhçıoğlu · 2019 · Journal of Nutrition and Dietetics
- Epigenetics in ExerciseMoran S. Saghiv, Michael S. Sagiv · 2020 · Springer eBooks
- Epigenetics, aging and early lifeRadhika Dhingra, Jamaji C. Nwanaji‐Enwerem, Allison E. Aiello, Francie Sentilles, B. G. King, Cavin K Ward-Caviness · 2020 · Elsevier eBooks
- Aging and SenescenceGary C. Howard · 2021 · Oxford University Press eBooks
- Stem Cell Quiescence versus Senescence: The Key for Healthy AgingAnna Meiliana, Nurrani Mustika Dewi, Andi Wijaya · 2021 · The Indonesian Biomedical Journal
- Epigenetic Modifications Involved in Ageing Process: The Role of Histone Methylation of SET-DomainPambu Lelo Aaron, Zakuani Luzinga Nadege, Fabrice Ndayisenga, Gédéon Ngiala Bongo · 2022 · Biochemistry
- Discovery of a Highly Selective Cell‐Active Inhibitor of the Histone Lysine Demethylases KDM2/7Philip A. Gerken, Jamie R. Wolstenhulme, Anthony Tumber, Stephanie B. Hatch, Yijia Zhang, Susanne Müller, Shane A. Chandler, Barbara Mair, Fengling Li, Sebastian M. B. Nijman et al. · 2017 · Angewandte Chemie
- Aging and DiseaseAndrea Fuso · 2018 · Elsevier eBooks
- Nutrigenomics of AgingNelma M. Palminha, Sara A. Hashish, Eman Rabie, S. Saber · 2022 · Nutritional neurosciences
- Mammalian Resilience Revealed by a Comparison of Human Diseases and Mouse Models Associated With DNA Helicase DeficienciesMasaoki Kohzaki · 2022 · Frontiers in Molecular Biosciences
- Epigenome editing in mice: The dawn of the reverse epigenetics eraIzuho Hatada, Sumiyo Morita, Takuro Horii · 2022 · Gene and Genome Editing
- Basic pathways and targets for anti-aging interventionMercedes Cano, Yiu To Yeung, Mario F. Muñoz, Antonio Ayala, Angélica Guerrero‐Castilla, Sandro Argüelles · 2023 · Elsevier eBooks
- Investigating the Causes of Cellular Aging and Uncovering the Novel Vision of Anti-aging TherapeuticsAshwin Prabahar A · 2023 · Journal of Clinical and Medical Research
- Association of Self Perception of Pre-Mature Ageing and Human Constitution (Prakriti) - A Cross-Sectional StudyRakesh Roushan · 2022 · Epidemiology International
- DECODER: A probabilistic approach to integrate big data reveals mitochondrial Complex I as a potential therapeutic target for Alzheimer’s diseaseSafiye Çelik, Joshua C. Russell, Cezar Rangel Pestana, Ting-I Lee, Shubhabrata Mukherjee, Paul K. Crane, Christopher Dirk Keene, Jennifer F. Bobb, Matt R. Kaeberlein, Su‐In Lee · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- DNA methylation change in neurotrophic genes with aging and delirium evidenced from three independent cohortsTaku Saito, Patricia Braun, Sophia Daniel, Sydney S. Jellison, Mandy M. Hellman, Eri Shinozaki, Sangil Lee, Hyunkeun R. Cho, Aihide Yoshino, Hiroyuki Toda et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Molecular Mechanisms Underlying Cardiometabolic Disease in AgingVíctor Fanjul · 2019
- Integrative Epigenomic and Transcriptomic Analysis Reveals Robust Metabolic Switching in the Brain During Intermittent FastingGavin Yong-Quan Ng, Dominic Paul Lee Kok Sheng, Sung Wook Kang, David Yang‐Wei Fann, Joonki Kim, Asfa Alli Shaik, Yoon Suk Cho, Jihoon Han, Jae Hoon Sul, Vardan T. Karamyan et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Single-cell epigenomic tracing of lifelong endothelial cell plasticity across mouse organsXianhong Yu, Yaxi Liu, Xiaoge Liu, Haiqing Xiong, Aibin He · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Análise longitudinal das condições de vida e saúde de idosos com histórico de câncer: Estudo Saúde, Bem-Estar e EnvelhecimentoTatiana Massaroli de [UNESP] Melo · 2021
- Epigenetics of post-operative delirium: A genome-wide DNA methylation study of neurosurgery patientsTakehiko Yamanashi, Kaitlyn J. Crutchley, Nadia E. Wahba, Takaaki Nagao, Pedro S. Marra, Cade C. Akers, Eleanor J. Sullivan, Masaaki Iwata, Matthew A. Howard, Hyunkeun R. Cho et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- On the Origin of Aging by Means of Natural SelectionRichard F. Walker · 2023 · Qeios
- Epigenetic Modifications and Their Relevance in the Normal and Pathological BrainLaura Lossi, Adalberto Merighi · 2023 · Preprints.org
- IFT20 and WWTR1 govern bone homeostasis via synchronously regulating the expression and stability of TβRII in osteoblast lineage cellsShuying Yang, Yang Li, Shuting Yang · 2024 · Research Square
- Epigenetic Reprogramming of Aging: Reversing the Clock for Regenerative MedicineMohammad Odah · 2024 · Preprints.org
- Modulating DNA Polα Enhances Cell Reprogramming Across SpeciesRajesh Ranjan, Binbin Ma, Ryan J. Gleason, Yijun Liao, Yingshan Bi, Brendon E. M. Davis, Guanghui Yang, Maggie Clark, Vikrant Mahajan, Madison Condon et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermisJúlia Bonjoch, Paloma Solá, Óscar Reina, Thomas Mortimer, Yekaterina A. Miroshnikova, Sara A. Wickström, Camille Stephan‐Otto Attolini, Laura Álvarez, Salvador Aznar Benitah, Guiomar Solanas · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- The aging transcriptome: a condition-dependent response to a deteriorating somaZeeshan Ali Syed, Martin Brengdahl, Vinesh Naresh Shenoi, Avani Mital, Christopher M. Kimber, Helen Ekman, Claudio Mirabello, Malin Larsson, David Berger, Urban Friberg · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Measuring Immunological Age: From T cell Repertoires to PopulationsElena N. Naumova, Yuri N. Naumov, Jack Gorski · 2017 · Springer eBooks
- Cytokine Polymorphisms, Immunosenescence, and NeurodegenerationOwen A. Ross, Ronald L. Walton, Kelly M. Hinkle, Neill R. Graff‐Radford, Irene Maeve Rea · 2017 · Springer eBooks
- CHARACTERISTICS OF GENOME REGULATORY ELEMENTSD.A. Oleynik, E.Yu Rodina · 2017 · International Journal of Applied and Fundamental Research (Международный журнал прикладных и фундаментальных исследований)
- Epigenome comparisons reveal linkage between gene expression and postnatal remodeling of chromatin domain topologyBruce H. Howard, Tazuko H. Hirai, Valya R. RUSSANOVA · 2018 · PLoS ONE
- Epigenetic heterogeneity revealed through single-cell DNA methylation sequencingZhao Hui · 2018 · cIRcle (University of British Columbia)
- Epigenetic Programming of Human Disease and AgingAlexander M. Vaiserman, Alexander K. Koliada, Oleh V. Lushchak · 2018 · Elsevier eBooks
- The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature AgingDido Carrero, Carlos López-Otı́n · 2018 · Springer eBooks
- Assessing the Effect of Epigenetic Dysregulation on Oncogenesis and Immunocompetence in a Mouse ModelJoseph Rosenthal · 2018 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
- Temporal inhibition of autophagy reveals segmental reversal of aging with increased cancer riskLiam D. Cassidy, Andrew R. J. Young, Chris Young, Elizabeth J. Soilleux, Edward Fielder, Bettina M. Weigand, Rebecca J. Brais, Kimberley A. Wiggins, Murray C.H. Clarke, Diana Jurk et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Modifiability of Longevity and Quality-of-Life Predictors of Older AdultsJessica Stephens, Mathew Fiedler, Michelle Lidell, Robert J. Gatchel · 2018 · Handbooks in health, work, and disability
- Epigenomic reprogramming of caloric restriction on agingS. Ribarič · 2019 · Nutritional Epigenomics
- Introductory Chapter: Epigenetics in SummaryRosaria Meccariello · 2019 · IntechOpen eBooks
- Epigenetics and imprinting in assisted reproductionDiego Marín, Emre U Seli · 2020 · Elsevier eBooks
- Epigenetics of the Aging Musculoskeletal SystemBoris Slobodin · 2020 · Springer eBooks
- Simultaneous transcriptome and methylome profiles of single mouse oocytes provide novel insights on maturation and agingQian Yan, Qin Cao, Jinyue Liao, Chun Shui Luk, Ashley Hoi Ching Suen, Annie Wing-Tung Lee, Ting Hei Thomas Chan, Judy Kin Wing Ng, Nelson L.S. Tang, Hoi Sze Chung et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- RNA and agingMilan Mušo · 2020 · Elsevier eBooks
- Hydroxytyrosol, olive oil, and use in agingMercedes Cano, Mario Muñoz, Antonio Ayala, Rafael Medina-Guzman, Sandro Argüelles · 2021 · Elsevier eBooks
- Aging Biomarkers-Disorders Characterized by Premature AgingDeeraja Manvi Gatta, Sai Sravani Botcha · 2021 · Biomarkers
- Targeting hepatic stellate cells to prevent or reverse liver fibrosisMengfan Zhang · 2020
- Histone Demethylase UTX Compromises Articular Chondrocyte Anabolism and Aggravates Osteoarthritic DegenerationWei‐Shiung Lian, Re‐Wen Wu, Jih‐Yang Ko, Yushan Chen, Shao-Yu Wang, Chun-Ping Yu, Holger Jahr, Fengsheng Wang · 2021 · Research Square
- Aging-associated changes in metabolic regulation of epigenetic modifications and gene expressionPoonam Bheda · 2021 · Elsevier eBooks
- Death in LifeGary C. Howard · 2021 · Oxford University Press eBooks
- Genetics of Life and DeathGary C. Howard · 2021 · Oxford University Press eBooks
- Death Is More than DyingGary C. Howard · 2021 · Oxford University Press eBooks
- H3K4me3 enrichment defines neuronal age, while a youthful H3K27ac signature is recapitulated in aged neuronsKatherine A. Giles, Andrew J. Phipps, Jake M. Cashion, Shannon N. Huskins, Tim R. Mercer, Mark D. Robinson, Adele Woodhouse, Phillippa C. Taberlay · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- BioethicsGary C. Howard · 2021 · Oxford University Press eBooks
- DyingGary C. Howard · 2021 · Oxford University Press eBooks
- Cell biologist’s perspective: Frontiers in Development of PROTAC-HDAC degraders.Alex Sobko · 2021
- Functional genomics of ageing: implications of chromatin landscape and beyondAntonis Kirmizis · 2022 · Briefings in Functional Genomics
- PhenotypeNancy B. Y. Tsui, Johnson Y.N. Lau · 2021 · Springer eBooks
- Faculty Opinions recommendation of Reprogramming to recover youthful epigenetic information and restore vision.Malcolm Maden · 2021 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- The annoying flaws of gerontological researchMagomed Khaidakov, Valeria Troshina, Dmitry Menglet, Yu N Yusef, Alexander Plotkin · 2022 · Drug Metabolism Reviews
- Aging Principles and Perspectives for InterventionSuresh I. S. Rattan · 2018 · Springer eBooks
- Epigenomic and transcriptomic analysis of developing, adult and aging brain: mechanisms of brain folding, neuronal function and finding novel therapy for dementiaM. Sadman Sakib · 2021
- Faculty Opinions recommendation of HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity.Seung‐Jae Lee, Yoonji Jung · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Age-dependent transcriptional and epigenetic alterations in mouse hepatocytesSharma, Ankur · 2021
- Effect of ageing on biochemical, genetic and epigenetic stability during seed storageMichela Pirredda · 2021
- Faculty Opinions recommendation of Reprogramming to recover youthful epigenetic information and restore vision.Pinghua Liu · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Faculty Opinions recommendation of Cytoplasmic chromatin triggers inflammation in senescence and cancer.Jing‐Dong J. Han · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Measuring Immunological Age: From T Cell Repertoires to PopulationsElena N. Naumova, Yuri N. Naumov, Jack Gorski · 2019 · Springer eBooks