Epigenetic mechanisms of longevity and aging
Sen, Payel, Shah, Parisha P., Nativio, Raffaella, Berger, Shelley L.·2016·Cell
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Items 201–300 of 962
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- Basic and translational aging research in China: present and futureMajor Program Expert Group, Xiaojuan He, Moshi Song, Jing Tao Qu, Yansu Guo, Heqi Cao, Ruijuan Sun, Guang‐Hui Liu, Yong Shen · 2019 · Protein & Cell
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- Tetrahydroberberrubine retards heart aging in mice by promoting PHB2-mediated mitophagyLei Wang, Xueqing Tang, Yang Shi, Huimin Li, Ziyu Meng, Hui Chen, Xiaohan Li, Yongchao Chen, Heng Liu, Yang Hong et al. · 2022 · Acta Pharmacologica Sinica
- Correlated evolution of social organization and lifespan in mammalsPingfen Zhu, Weiqiang Liu, Xiaoxiao Zhang, Meng Li, Gaoming Liu, Yang Yu, Xuanjing Li, Xuanjing Li, Juan Du, Xiao Wang et al. · 2023 · Nature Communications
- Mechanisms of immune aging in HIVManon Chauvin, Delphine Sauce · 2022 · Clinical Science
- An analysis of aging-related genes derived from the Genotype-Tissue Expression project (GTEx)Kaiwen Jia, Chunmei Cui, Yuanxu Gao, Yuan Zhou, Qinghua Cui · 2018 · Cell Death Discovery
- Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule CellsXiaobin Han, Zhongjie Sun · 2020 · Hypertension
- Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer’s diseaseEmma Coninx, Yap Ching Chew, Xiaojing Yang, Wei Guo, Amelie Coolkens, Sarah Baatout, Lieve Moons, Mieke Verslegers, Roel Quintens · 2020 · Aging
- The hallmarks of aging in Ataxia-TelangiectasiaJulio Aguado, Cecilia Gómez‐Inclán, Hannah C. Leeson, Martin Francis Lavin, Yosef Shiloh, Ernst Jurgen Wolvetang · 2022 · Ageing Research Reviews
- Aberrant G protein-receptor expression is associated with DNA methylation in aldosterone-producing adenomaKiyotaka Itcho, Kenji Oki, Kazuhiro Kobuke, Yoko Yoshii, Haruya Ohno, Masayasu Yoneda, Noboru Hattori · 2017 · Molecular and Cellular Endocrinology
- Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiationMaria A. Hahn, Seung‐Gi Jin, Arthur X. Li, Jiancheng Liu, Zhijun Huang, Xiwei Wu, Byung-Wook Kim, Jennifer S. Johnson, Adrienne-Denise V. Bilbao, Shu Tao et al. · 2019 · Science Advances
- The multi-faceted impact of methamphetamine on Alzheimer's disease: From a triggering role to a possible therapeutic use.M. Shukla, B. Vincent · 2020 · Ageing Research Reviews
- Heterogeneity of Cellular Senescence: Cell Type-Specific and Senescence Stimulus-Dependent Epigenetic AlterationsKatarzyna Malgorzata Kwiatkowska, Eleni Mavrogonatou, Adamantia Papadopoulou, Claudia Sala, Luciano Calzari, Davide Gentilini, Maria Giulia Bacalini, Daniele Dall’Olio, Gastone Castellani, Francesco Ravaioli et al. · 2023 · Cells
- Loss of Epigenetic Information as a Cause of Mammalian AgingJae-Hyun Yang, Motoshi Hayano, Patrick T. Griffin, João A. Amorim, Michael S. Bonkowski, John K. Apostolides, Marco Blanchette, Elizabeth M. Munding, Mital S. Bhakta, Elias Salfati et al. · 2021 · SSRN Electronic Journal
- The Emerging View of Aging as a Reversible Epigenetic ProcessMicaela López-León, Rodolfo Gustavo Goya · 2017 · Gerontology
- Association of Klotho with physical performance and frailty in middle-aged and older adults: A systematic reviewFrancesca Veronesi, Veronica Borsari, Antonio Cherubini, Milena Fini · 2021 · Experimental Gerontology
- T cell aging as a risk factor for autoimmunityQingxiang Liu, Yanyan Zheng, Jörg J. Goronzy, Cornelia M. Weyand · 2022 · Journal of Autoimmunity
- Unveiling the epigenetic impact of vegan vs. omnivorous diets on aging: insights from the Twins Nutrition Study (TwiNS)Varun Bhamidipati Dwaraka, Lucia Aronica, Natàlia Carreras-Gallo, Jennifer L. Robinson, Tayler Hennings, Matthew M. Carter, Michael J. Corley, Aaron Lin, Logan Turner, Ryan C. Smith et al. · 2024 · BMC Medicine
- Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein responseSayaka Sobue, Chisato Inoue, Fumiko Hori, Shanlou Qiao, Takashi Murate, Masatoshi Ichihara · 2017 · Biochemical and Biophysical Research Communications
- Discovery of a Highly Selective Cell‐Active Inhibitor of the Histone Lysine Demethylases KDM2/7Philip A. Gerken, Jamie R. Wolstenhulme, Anthony Tumber, Stephanie B. Hatch, Yijia Zhang, Susanne Müller, Shane A. Chandler, Barbara Mair, Fengling Li, Sebastian M. B. Nijman et al. · 2017 · Angewandte Chemie International Edition
- Multi-level remodeling of transcriptional landscapes in aging and longevityRochelle W. Lai, Ryan J. Lu, Prakroothi S. Danthi, Juan I. Bravo, Alexandre Goumba, Nirmal Kumar Sampathkumar, Bérénice Anath Benayoun · 2019 · BMB Reports
- The Aging Stress Response and Its Implication for AMD PathogenesisJanusz Błasiak, Elżbieta Pawłowska, Anna Sobczuk, Joanna Szczepańska, Kai Kaarniranta · 2020 · International Journal of Molecular Sciences
- Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathologyLasse Pihlstrøm, Gemma L. Shireby, Hanneke Geut, Sandra Pilar Henriksen, Annemieke J.M. Rozemüller, Jon‐Anders Tunold, Eilis J. Hannon, Paul T. Francis, Alan J. Thomas, Seth Love et al. · 2022 · Nature Communications
- Epigenetic signature in neural plasticity: the journey so far and journey aheadNayak, Madhusmita, Das, Diptimayee, Pradhan, Jyotsnarani, Ahmed, R.G., Laureano-Melo, Roberto, Dandapat, Jagneshwar · 2022 · Heliyon
- Muscle-Specific Histone H3K36 Dimethyltransferase SET-18 Shortens Lifespan of Caenorhabditis elegans by Repressing daf-16a ExpressionLiangping Su, Hongyuan Li, Cheng Huang, Tingting Zhao, Yongjun Zhang, Xueqing Ba, Zhongwei Li, Yu Zhang, Baiqu Huang, Jun Lü et al. · 2018 · Cell Reports
- UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genesSera, Yasuyuki, Nakata, Yuichiro, Ueda, Takeshi, Yamasaki, Norimasa, Koide, Shuhei, Kobayashi, Hiroshi, Ikeda, Ken-ichiro, Kobatake, Kohei, Iwasaki, Masayuki, Oda, Hideaki et al. · 2021 · Blood
- Early‐onset aging and mitochondrial defects associated with loss of histone acetyltransferase 1 (Hat1)Nagarajan, Prabakaran, Agudelo Garcia, Paula A., Iyer, Chitra C., Popova, Liudmila V., Arnold, William D., Parthun, Mark R. · 2019 · Aging Cell
- Reprogramming neurons for regeneration: The fountain of youthShuguang Yang, Xuewei Wang, Cheng Qian, Feng‐Quan Zhou · 2022 · Progress in Neurobiology
- Bazi Bushen mitigates epigenetic aging and extends healthspan in naturally aging miceXinjing Mao, Yunlong Hou, Chao Fang, Kun Ma, Shixiong Zhang, Zhifang Guo, Ning Kang, Kunxu Niu, Xiaogang Shen, Yawen Li et al. · 2023 · Biomedicine & Pharmacotherapy
- Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With AgingGen Shinozaki, Patricia Braun, Benjamin Wen Qing Hing, Andrew D. Ratanatharathorn, Mason J. Klisares, Gabrielle N. Duncan, Sydney S. Jellison, Jonathan T. Heinzman, Yasunori Nagahama, Liesl N. Close et al. · 2018 · Frontiers in Aging Neuroscience
- Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine ExpansionAnna Niewiadomska-Cimicka, Antoine Hache, Yvon Trottier · 2020 · Frontiers in Neuroscience
- The ageing lung under stressMartina Korfei, BreAnne MacKenzie, Silke Meiners · 2020 · European Respiratory Review
- Potential of Caenorhabditis elegans as an antiaging evaluation model for dietary phytochemicals: A reviewYongli Ye, Qingyin Gu, Xiulan Sun · 2020 · Comprehensive Reviews in Food Science and Food Safety
- Integrated multi-omics approach revealed cellular senescence landscapeQiao Song, Yuli Hou, Yiyin Zhang, Jing Liu, Yaqi Wang, Jingxuan Fu, Chi Zhang, Min Cao, Yuting Cui, Xiaomin Zhang et al. · 2022 · Nucleic Acids Research
- Reversing age: dual species measurement of epigenetic age with a single clockSteve Horvath, Kavita Singh, Ken Raj, Shraddha I. Khairnar, Akshay Sanghavi, Agnivesh Shrivastava, Joseph Alan Zoller, Caesar Z. Li, Claudia Beatriz Hereñú, Martina Canatelli-Mallat et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Epigenetic modulators provide a path to understanding disease and therapeutic opportunityMadison A. Honer, Benjamin I. Ferman, Zach H. Gray, Elena A. Bondarenko, Johnathan R. Whetstine · 2024 · Genes & Development
- DNA methylation regulator-mediated modification patterns and risk of intracranial aneurysm: a multi-omics and epigenome-wide association study integrating machine learning, Mendelian randomization, eQTL and mQTL dataAierpati Maimaiti, Mirzat Turhon, Aimitaji Abulaiti, Yilidanna Dilixiati, Fujunhui Zhang, Aximujiang Axier, Kaheerman Kadeer, Yisen Zhang, Aisha Maimaitili, Xinjian Yang · 2023 · Journal of Translational Medicine
- METTL3 promotes cellular senescence of colorectal cancer via modulation of CDKN2B transcription and mRNA stabilityZhuojia Chen, Jiawang Zhou, You Wu, Feng Chen, Jianing Li, Lijun Tao, Yifan Tian, Haoran Wang, Zigang Li, Zigang Li et al. · 2024 · Oncogene
- Epigenetic predictors of species maximum life span and other life-history traits in mammalsCaesar Z. Li, Amin Haghani, T.R. Robeck, D. Villar, A.T. Lu, J. Zhang, C.G. Faulkes, X. William Yang, J. Ablaeva, D.M. Adams et al. · 2024 · Science Advances
- The histone variant H3.3 claims its place in the crowded scene of epigeneticsDaniele Bano, Antonia Piazzesi, Paolo Salomoni, Pierluigi Nicotera · 2017 · Aging
- Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress responseSeunghee Oh, Tamaki Suganuma, Madelaine Gogol, Jerry L. Workman · 2018 · eLife
- Ubiquitylome study identifies increased histone 2A ubiquitylation as an evolutionarily conserved aging biomarkerYang Lü, Zaijun Ma, Han Wang, Kongyan Niu, Ye Cao, Le Sun, Yang Geng, Bo Yang, Feng Gao, Zuolong Chen et al. · 2019 · Nature Communications
- Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: a role for Wnt/β-catenin signalingRicardo Gómez-Oliva, Noelia Geribaldi-Doldán, Samuel Domínguez-García, Livia Carrascal, Cristina Verástegui, Pedro Nunez-Abades, Carmen Castro · 2020 · Aging
- Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inferencePaul J. Hop, René Luijk, Lucia Daxinger, Maarten van Iterson, Koen F. Dekkers, Rick Jansen, Bastiaan T. Heijmans, Peter A.C. ’t Hoen, Joyce B. J. van Meurs, Rick Jansen et al. · 2020 · Genome biology
- HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevitySurojit Sural, Chung‐Yi Liang, Feng‐Yung Wang, Tsui‐Ting Ching, Ao‐Lin Hsu · 2020 · Science Advances
- Age as a risk factor in vasculitisAndrea D. Gloor, Gerald J. Berry, Jörg J. Goronzy, Cornelia M. Weyand · 2022 · Seminars in Immunopathology
- Insights into the biochemical and biophysical mechanisms mediating the longevity of the transparent optics of the eye lensRoy A. Quinlan, John I. Clark · 2022 · Journal of Biological Chemistry
- Influence of human gut microbiome on the healthy and the neurodegenerative agingAlejandro Borrego-Ruiz, Juan José Borrego · 2024 · Experimental Gerontology
- Epigenetic Regulation of Aging and its RejuvenationYongpan An, Qian Wang, Ke Gao, Chi Zhang, Yanan Ouyang, Ruixiao Li, Ma Zhou, Tong Wu, Lifan Zhou, Zhengwei Xie et al. · 2025 · MedComm
- Angiotensin II Type 1 Receptor‐Associated Protein Regulates Kidney Aging and Lifespan Independent of AngiotensinKazushi Uneda, Hiromichi Wakui, Akinobu Maeda, Kengo Azushima, Ryu Kobayashi, Sona Haku, Kohji Ohki, Kotaro Haruhara, Sho Kinguchi, Miyuki Matsuda et al. · 2017 · Journal of the American Heart Association
- KDM2A/B lysine demethylases and their alternative isoforms in development and diseaseTomáš Vacı́k, Dijana Lađinović, Ivan Raška · 2018 · Nucleus
- Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of LongevityAlexey Moskalev, Mikhail Vyacheslavovich Shaposhnikov, Nadezhda Vladimirovna Zemskaya, Liubov A. Koval, Eugenia V. Schegoleva, Zulfiya G. Guvatova, George Sergeevich Krasnov, Ilya A. Solovev, Maksim A. Sheptyakov, Alex A. Zhavoronkov et al. · 2019 · Scientific Reports
- Aryl hydrocarbon receptor (AhR) impairs circadian regulation: Impact on the aging processAntero Salminen · 2023 · Ageing Research Reviews
- KMT2A regulates the autophagy-GATA4 axis through METTL3-mediated m6A modification of ATG4a to promote NPCs senescence and IVDD progressionOuqiang Wu, Yuxin Jin, Zhiguang Zhang, Hao Zhou, Wenbin Xu, Linjie Chen, Morgan E. B. Jones, Kenny Yat-Hong Kwan, Jianyuan Gao, Kai Zhang et al. · 2024 · Bone Research
- Analysis of DNA modifications in aging researchDustin R. Masser, Niran Hadad, Hunter L. Porter, Michael B. Stout, Archana Unnikrishnan, David R. Stanford, Willard M. Freeman · 2018 · GeroScience
- CRL4DCAF8 dependent opposing stability control over the chromatin remodeler LSH orchestrates epigenetic dynamics in ferroptosisDaoyuan Huang, Qian Li, Xinpei Sun, Xiwen Sun, Yunyi Tang, Yanan Qu, Dawei Liu, Tingting Yu, Guodong Li, Tanjun Tong et al. · 2020 · Cell Death and Differentiation
- Epigenetic dysregulation in cardiovascular aging and diseaseAllison B. Herman, James R. Occean, Payel Sen · 2021 · The Journal of Cardiovascular Aging
- Anti-aging effects of dietary phytochemicals: From Caenorhabditis elegans , Drosophila melanogaster , rodents to clinical studiesJu-Chi Chen, Reuben Wang, Chia‐Cheng Wei · 2023 · Critical Reviews in Food Science and Nutrition
- The role of dietary strategies in the modulation of hallmarks of agingNatasha Aparecida Grande de França, Yves Rolland, Sophie Guyonnet, Philipe de Souto Barreto · 2023 · Ageing Research Reviews
- Multimodal Omics Approaches to Aging and Age-Related DiseasesQian-Zhao Ji, Xiao-Yu Jiang, Min-Xian Wang, Zi-Juan Xin, Wei-Qi Zhang, J. Qu, Guang-Hui Liu · 2024 · Phenomics
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- The impact of ageing mechanisms on musculoskeletal system diseases in the elderlyYijin Cai, Zhongyu Han, Hong Cheng, Hongpeng Li, Ke Wang, Jia Chen, Zhixiang Liu, Yu‐Long Xie, Yumeng Lin, Shuwei Zhou et al. · 2024 · Frontiers in Immunology
- Epigenetic Clock: Just a Convenient Marker or an Active Driver of Aging?Vasily V. Ashapkin, Lyudmila I. Kutueva, B. F. Vanyushin · 2019 · Advances in experimental medicine and biology
- Spurious intragenic transcription is a feature of mammalian cellular senescence and tissue agingPayel Sen, Greg Donahue, Catherine Y. Li, Gabor Egervári, Na Yang, Yemin Lan, Neil Robertson, Parisha P. Shah, Erik Kerkhoven, D. Schultz et al. · 2023 · Nature Aging
- The Molecular Mechanisms in Senescent Cells Induced by Natural Aging and Ionizing RadiationMilana Ibragimova, Assiya Kussainova, Akmaral Aripova, Rakhmetkazhi I. Bersimbaev, Olga Bulgakova · 2024 · Cells
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- Aging extension and modifications of lipid metabolism in the monogonont rotifer Brachionus koreanus under chronic caloric restrictionMin‐Chul Lee, Jun Chul Park, Deok-Seo Yoon, Jeonghoon Han, Sujin Kang, Shohei Kamizono, Ae‐Son Om, Kyung‐Hoon Shin, Atsushi Hagiwara, Jae‐Seong Lee · 2018 · Scientific Reports
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- Epigenetic treatment of behavioral and physiological deficits in a tauopathy mouse modelWei Wang, Qing Cao, Tao Tan, Fengwei Yang, Jamal B. Williams, Zhen Yan · 2021 · Aging Cell
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