Epigenetic mechanisms of longevity and aging
Sen, Payel, Shah, Parisha P., Nativio, Raffaella, Berger, Shelley L.·2016·Cell
Cited by (962)
Items 101–200 of 962
- The loss of heterochromatin is associated with multiscale three-dimensional genome reorganization and aberrant transcription during cellular senescenceXiang-Lin Zhang, Xue-Hui Liu, Zhenhai Du, Lei Wei, Huan Fang, Qiongye Dong, Jing Niu, Yan-Da Li, Juntao Gao, Michael Q. Zhang et al. · 2021 · Genome Research
- Abnormal Epigenetic Regulation of Immune System during AgingMiriam Galvonas Jasiulionis · 2018 · Frontiers in Immunology
- Epigenomic analysis of Parkinson’s disease neurons identifies Tet2 loss as neuroprotectiveLee L. Marshall, Bryan A. Killinger, Elizabeth Ensink, Peipei Li, Katie X. Li, Wei Cui, Noah Lubben, Matthew J. Weiland, Xinhe Wang, Juozas Gordevičius et al. · 2020 · Nature Neuroscience
- Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegansQin-Li Wan, Xiao Meng, Chongyang Wang, Wenyu Dai, Zhenhuan Luo, Zhinan Yin, Zhenyu Ju, Xiaodie Fu, Jing Yang, Qunshan Ye et al. · 2022 · Nature Communications
- HDAC inhibitors: A new promising drug class in anti-aging researchPasyukova, Elena G., Vaiserman, Alexander M. · 2017 · Mechanisms of Ageing and Development
- Sex Differences in Aging: Genomic InstabilityKathleen E. Fischer, Nicole C. Riddle · 2017 · The Journals of Gerontology Series A
- Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?Alexander M. Vaiserman, Alexander K. Koliada · 2017 · Human Genomics
- The mitochondrial unfolded protein response: A multitasking giant in the fight against human diseasesZixin Zhou, Yumei Fan, Ruikai Zong, Ke Tan · 2022 · Ageing Research Reviews
- Small-molecule induction of Aβ-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypesSerena Pavoni, Rafika Jarray, Férid Nassor, Anne-Cécile Guyot, Steve Cottin, Jessica Rontard, Jacqueline Mikol, Aloïse M Mabondzo, Jean‐Philippe Deslys, Frank Yates · 2018 · PLoS ONE
- Epigenetic clocks, aging, and cancerSarah E. Johnstone, Vadim N. Gladyshev, Martin J. Aryee, B Bernstein · 2022 · Science
- An Overview of the Epigenetic Modifications in the Brain under Normal and Pathological ConditionsLaura Lossi, Claudia Castagna, Adalberto Merighi · 2024 · International Journal of Molecular Sciences
- Epigenetic Mechanisms Impacting Aging: A Focus on Histone Levels and TelomeresShufei Song, F Brad Johnson · 2018 · Genes
- Biological ageing with HIV infection: evaluating the geroscience hypothesisMonty A Montano, Krisann K. Oursler, Ke Xu, Yan V. Sun, Vincent C. Marconi · 2022 · The Lancet Healthy Longevity
- Cellular senescence in cancer: clinical detection and prognostic implicationsDomen, Andreas, Deben, Christophe, Verswyvel, Jasper, Flieswasser, Tal, Prenen, Hans, Peeters, Marc, Lardon, Filip, Wouters, An · 2022 · Journal of Experimental & Clinical Cancer Research
- Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brainZhang, Yanxiao, Amaral, Maria Luisa, Zhu, Chenxu, Grieco, Steven Francis, Hou, Xiaomeng, Lin, Lin, Buchanan, Justin, Tong, Liqi, Preissl, Sebastian, Xu, Xiangmin et al. · 2022 · Cell Research
- Nutrition and longevity—From mechanisms to uncertaintiesEkmekcioglu, Cem · 2020 · Critical Reviews in Food Science and Nutrition
- Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer’s disease mouse modelChristian Griñán‐Ferré, Laura Marsal-García, Aina Bellver‐Sanchís, Shukkoor Muhammed Kondengaden, Ravi Chakra Turaga, Santiago Vázquez, Mercè Pallàs · 2019 · Aging
- ATF3 drives senescence by reconstructing accessible chromatin profilesZhang, Chao, Zhang, Xuebin, Huang, Li, Guan, Yiting, Huang, Xiaoke, Tian, Xiao‐Li, Zhang, Lijun, Tao, Wei · 2021 · Aging Cell
- Genetic and epigenetic dependencies in colorectal cancer developmentSehej Parmar, Hariharan Easwaran · 2022 · Gastroenterology report
- Chromatin Architectural Changes during Cellular Senescence and AgingLuyang Sun, Ruofan Yu, Weiwei Dang · 2018 · Genes
- Improvements to Healthspan Through Environmental Enrichment and Lifestyle Interventions: Where Are We Now?Nicholas J. Queen, Quais N. Hassan, Lei Cao · 2020 · Frontiers in Neuroscience
- Transcriptional elongation control in developmental gene expression, aging, and diseaseYuki Aoi, Ali Shilatifard · 2023 · Molecular Cell
- CISD2 maintains cellular homeostasisZhao‐Qing Shen, Yi‐Long Huang, Yuan‐Chi Teng, Tai-Wen Wang, Cheng‐Heng Kao, Chi‐Hsiao Yeh, Ting‐Fen Tsai · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosisSakiko Honda, Koji Ikeda, Ryota Urata, Ekura Yamazaki, Noriaki Emoto, Satoaki Matoba · 2021 · Scientific Reports
- Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigeneticsMartin Sebastian Denzel, Louis R. Lapierre, Hildegard I. D. Mack · 2018 · Mechanisms of Ageing and Development
- DNA Methylation in Epidermal Differentiation, Aging, and CancerFlorian Köhler, Manuel Rodríguez‐Paredes · 2019 · Journal of Investigative Dermatology
- Tissue-specific impacts of aging and genetics on gene expression patterns in humansRyo Yamamoto, Ryan Chung, Juan Manuel Vázquez, Huanjie Sheng, Philippa L. Steinberg, Nilah M. Ioannidis, Peter H. Sudmant · 2022 · Nature Communications
- Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic AnalysisShcherbina, Anna, Larouche, Jacqueline, Fraczek, Paula, Yang, Benjamin A., Brown, Lemuel A., Markworth, James F., Chung, Carolina H., Khaliq, Mehwish, de Silva, Kanishka, Choi, Jeongmoon J. et al. · 2020 · Cell Reports
- Mechanistic Insights Into the Interaction Between Transcription Factors and Epigenetic Modifications and the Contribution to the Development of ObesityHuang, Qi, Ma, Chaoyang, Chen, Li, Luo, Dan, Chen, Rui, Liang, Fengxia · 2018 · Frontiers in Endocrinology
- A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageingYuxuan Lu, Jennifer C. Regan, Jacqueline Eßer, Lisa F. Drews, Thomas Weinseis, Julia Stinn, Oliver Hahn, Richard A. Miller, Sebastian Grönke, Linda Partridge · 2021 · eLife
- Epigenomic drivers of immune dysfunction in agingChristine R. Keenan, Rhys S. Allan · 2018 · Aging Cell
- Epigenetic mechanisms related to cognitive decline during agingMaría Florencia Harman, Mauricio G. Martín · 2019 · Journal of Neuroscience Research
- Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue RegenerationMailyn A. Nishiguchi, Casey A. Spencer, Denis H. Y. Leung, Thomas Leung · 2018 · Cell Reports
- Ergothioneine and its congeners: anti-ageing mechanisms and pharmacophore biosynthesisLi Chen, Liping Zhang, Xujun Ye, Zixin Deng, Changming Zhao · 2023 · Protein & Cell
- Opening up the DNA methylome of dementiaRaúl Delgado‐Morales, Manel Esteller · 2017 · Molecular Psychiatry
- Interaction between epigenetic and metabolism in aging stem cellsAnne Brunet, Thomas A. Rando · 2017 · Current Opinion in Cell Biology
- The senescent cell epigenomeNa Yang, Payel Sen · 2018 · Aging
- Histone Methyltransferase EZH2: A Potential Therapeutic Target for Kidney DiseasesTingting Li, Chao Yu, Shougang Zhuang · 2021 · Frontiers in Physiology
- Exploring the Communication of the SASP: Dynamic, Interactive, and Adaptive Effects on the MicroenvironmentJoëlle Giroud, Inès Bouriez, Hugo Paulus, Albin Pourtier, Florence Debacq‐Chainiaux, Olivier Pluquet · 2023 · International Journal of Molecular Sciences
- Kidney and epigenetic mechanisms of salt-sensitive hypertensionWakako Kawarazaki, Toshiro Fujita · 2021 · Nature Reviews Nephrology
- Environmental Impact on the Epigenetic Mechanisms Underlying Parkinson’s Disease Pathogenesis: A Narrative ReviewEfthalia Angelopoulou, Yam Nath Paudel, Sokratis G. Papageorgiou, Christina Piperi · 2022 · Brain Sciences
- Sex differences in antioxidant defence and the regulation of redox homeostasis in physiology and pathologyJessica Tiberi, Valeriana Cesarini, Roberta Stefanelli, Sonia Canterini, Maria Teresa Fiorenza, Piergiorgio La Rosa · 2023 · Mechanisms of Ageing and Development
- The Aging Thyroid: A Reappraisal Within the Geroscience Integrated PerspectiveClaudio Franceschi, Rita Ostan, Stefano Mariotti, Daniela Monti, Giovanni Vitale · 2019 · Endocrine Reviews
- m6A hypomethylation of DNMT3B regulated by ALKBH5 promotes intervertebral disc degeneration via E4F1 deficiencyGaocai Li, Rongjin Luo, Weifeng Zhang, Shujie He, Bingjin Wang, Huaizhen Liang, Yu Song, Wencan Ke, Yunsong Shi, Xiaobo Feng et al. · 2022 · Clinical and Translational Medicine
- Repetitive elements in aging and neurodegenerationCopley, Katie E., Shorter, James · 2023 · Trends in Genetics
- Sexually divergent DNA methylation patterns with hippocampal agingDustin R. Masser, Niran Hadad, Hunter L. Porter, Colleen A. Mangold, Archana Unnikrishnan, Matthew M. Ford, Cory B. Giles, Constantin Georgescu, Mikhail G. Dozmorov, Jonathan D. Wren et al. · 2017 · Aging Cell
- Epigenetic mechanisms underlying nervous system diseasesIrfan Qureshi, Mark F. Mehler · 2018 · Handbook of clinical neurology
- How to Measure Population Aging? The Answer Is Less than Obvious: A ReviewVegard Skirbekk, Ursula M. Staudinger, Joel E. Cohen · 2018 · Gerontology
- Aging of the Retina: Molecular and Metabolic Turbulences and Potential InterventionsLaura Campello, Nivedita Singh, Jayshree Advani, Anupam K. Mondal, Ximena Corso‐Díaz, Anand Swaroop · 2021 · Annual Review of Vision Science
- Pan-cancer analysis reveals molecular patterns associated with ageYajas Shah, Akanksha Verma, Andrew R. Marderstein, Jessica B. White, Bhavneet Bhinder, J. Sebastian Garcia Medina, Olivier Elemento · 2021 · Cell Reports
- Cardiomyocyte ageing and cardioprotection: consensus document from the ESC working groups cell biology of the heart and myocardial functionRuiz-Meana, Marisol, Bou-Teen, Diana, Ferdinandy, Péter, Gyongyosi, Mariann, Pesce, Maurizio, Perrino, Cinzia, Schulz, Rainer, Sluijter, Joost P G, Tocchetti, Carlo G, Thum, Thomas et al. · 2020 · Cardiovascular Research
- A hyper-quiescent chromatin state formed during aging is reversed by regenerationNa Yang, James R. Occean, Daniël P. Melters, Changyou Shi, Lin Wang, Stephanie Stransky, Maı̀re E. Doyle, Chang‐Yi Cui, Michael R. Delannoy, Jinshui Fan et al. · 2023 · Molecular Cell
- Vascular senescence and aging: mechanisms, clinical implications, and therapeutic prospectsAitor Picos, Nuria Seoane, Manuel Campos‐Toimil, Dolores Viña · 2025 · Biogerontology
- Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative DiseasesZsolt Kovács, Brigitta Brunner, Csilla Ari · 2021 · Nutrients
- Altered chromatin states drive cryptic transcription in aging mammalian stem cellsBrenna S. McCauley, Luyang Sun, Ruofan Yu, Minjung Lee, Haiying Liu, Dena S. Leeman, Yun Huang, Ashley E. Webb, Weiwei Dang · 2021 · Nature Aging
- Nutrients and Pathways that Regulate Health Span and Life SpanCarla Pignatti, Stefania D’Adamo, Claudio Stefanelli, Flavio Flamigni, Silvia Cetrullo · 2020 · Geriatrics
- The Mechanism of Bone Remodeling After Bone AgingHuankun Fang, Zhiqin Deng, Jianquan Liu, Siyu Chen, Zhenhan Deng, Wencui Li · 2022 · Clinical Interventions in Aging
- AP ‐1 is a regulatory transcription factor of inflammaging in the murine kidney and liverXiaojie Yu, Yuting Wang, Yifan Song, Xianda Gao, Hongkui Deng · 2023 · Aging Cell
- The role of patient-specific variables in protein corona formation and therapeutic efficacy in nanomedicineEthan P. Cisneros, Brinkley A. Morse, Ani Savk, Khyati Malik, Nicholas A. Peppas, Olivia L. Lanier · 2024 · Journal of Nanobiotechnology
- Advantages and disadvantages of apoptosis in the aging processSandro Argüelles, Angélica Guerrero‐Castilla, Mercedes Cano, Mario Muñoz, Antonio Ayala · 2019 · Annals of the New York Academy of Sciences
- Shared genetic and epigenetic changes link aging and cancerDaniel J. Zabransky, Elizabeth M. Jaffee, Ashani T. Weeraratna · 2022 · Trends in Cell Biology
- Metabolic regulation of lifespan from a C. elegans perspectiveKathrine B. Dall, Nils Joakim Færgeman · 2019 · Genes & Nutrition
- A DNA methylation age predictor for zebrafishBenjamin T. Mayne, Darren J. Korbie, Lisa M Kenchington, Ben J Ezzy, Oliver Berry, Simon Jarman · 2020 · Aging
- The role of the microbiota in sedentary lifestyle disorders and ageing: lessons from the animal kingdomPaul William O’Toole, Paul G. Shiels · 2020 · Journal of Internal Medicine
- Targeting Sirtuin1 to treat aging-related tissue fibrosis: From prevention to therapyXin Han, Chuan Ding, Xianan Sang, Mengyun Peng, Qiao Yang, Yan Ning, Qiang Lv, Qiyuan Shan, Min Hao, Kui-Long Wang et al. · 2021 · Pharmacology & Therapeutics
- Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogrammingAndrea Cipriano, Mahdi Moqri, Sun Y. Maybury‐Lewis, Ryan Rogers-Hammond, Tineke Anna de Jong, Alexander Parker, Sajede Rasouli, Hans Robert Schöler, David A. Sinclair, Vittorio Sebastiano · 2023 · Nature Aging
- Cellular Senescence in Human Skin Aging: Leveraging SenotherapeuticsSaranya P. Wyles, JEAN D. A. CARRUTHERS, Parisa Dashti, Grace Yu, Jane Q. Yap, Anne Gingery, Tamar Tchkonia, James L. Kirkland · 2023 · Gerontology
- MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain agingJason R. Kennerdell, Nan Liu, Nancy M. Bonini · 2018 · Nature Communications
- A novel strategy for the diagnosis, prognosis, treatment, and chemoresistance of hepatocellular carcinoma: DNA methylationAimei Liu, Qinghua Wu, Dapeng Peng, Irma Arés, Arturo Anadón, Bernardo López-Torres, María‐Rosa Martínez‐Larrañaga, Xu Wang, María‐Aránzazu Martínez · 2020 · Medicinal Research Reviews
- Metabolomic signature associated with reproduction-regulated aging in Caenorhabditis elegansQin-Li Wan, Xiaohuo Shi, Jiangxin Liu, Ai-Jun Ding, Yuan-Zhu Pu, Zhigang Li, Gui-Sheng Wu, Huai‐Rong Luo · 2017 · Aging
- Osthole improves function of periodontitis periodontal ligament stem cells via epigenetic modification in cell sheets engineeringJin Sun, Zhiwei Dong, Yang Zhang, Xiaoning He, Dongdong Fei, Fang Jin, Lin Yuan, Bei Li, Yan J. Jin · 2017 · Scientific Reports
- Epigenetics of T cell agingGoronzy, Jörg J, Hu, Bin, Kim, Chulwoo, Jadhav, Rohit R, Weyand, Cornelia M · 2018 · Journal of Leukocyte Biology
- The complex activities of the SET1/MLL complex core subunits in development and diseaseHao Jiang · 2020 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- The Jekyll and Hyde of Cellular Senescence in CancerDilara Demirci, Bengisu Dayanc, Fatma Aybuke Mazi, Şerif Şentürk · 2021 · Cells
- Interaction Among Sex, Aging, and Epigenetic Processes Concerning Visceral Fat, Insulin Resistance, and DyslipidaemiaAna Arpón, Fermin Ignacio Milagro, José Luis Santos, Marta García‐Granero, José Ignacio Riezu‐Boj, José Alfredo Martínez · 2019 · Frontiers in Endocrinology
- What have we learned on aging from omics studies?Alessandro Cellerino, Alessandro Ori · 2017 · Seminars in Cell and Developmental Biology
- Successful generation of epigenetic disease model mice by targeted demethylation of the epigenomeTakuro Horii, Sumiyo Morita, Shinjiro Hino, Mika Kimura, Yuko Hino, Hiroshi Kogo, Mitsuyoshi Nakao, Izuho Hatada · 2020 · Genome biology
- Age-related memory decline, dysfunction of the hippocampus and therapeutic opportunities.L. Dahan, C. Rampon, C. Florian · 2020 · Progress in Neuro-psychopharmacology and Biological Psychiatry
- Senescence-Induced Chemoresistance in Triple Negative Breast Cancer and Evolution-Based Treatment StrategiesAnindita Chakrabarty, Shayantani Chakraborty, Ranjini Bhattacharya, Goutam Chowdhury · 2021 · Frontiers in Oncology
- How to Slow down the Ticking Clock: Age-Associated Epigenetic Alterations and Related Interventions to Extend Life SpanAnne-Marie Galow, Shahaf Peleg · 2022 · Cells
- Biogerontology: research status, challenges and opportunities.Suresh I. S. Rattan · 2018 · Acta bio-medica dell'Ateneo parmense/Acta biomedica
- Immunosenescence and Altered Vaccine Efficiency in Older Subjects: A Myth Difficult to ChangeTamàs Fülöp, Anis Larbi, Graham Pawelec, Alan Arthur Cohen, Guillaume Provost, Abdelouahed Khalil, Guy Lacombe, Serafim Rodrigues, Mathieu Desroches, Katsuiku Hirokawa et al. · 2022 · Vaccines
- Mettl3-dependent m6A modification attenuates the brain stress response in DrosophilaAlexandra E. Perlegos, Emily J. Shields, Hui Shen, Kathy Fange Liu, Nancy M. Bonini · 2022 · Nature Communications
- Dynamic Regulation of DNA Methylation and Brain FunctionsJiaxiang Xie, Leijie Xie, Huixian Wei, Xiao‐Jiang Li, Lin Li · 2023 · Biology
- Chromatin and MetabolismTamaki Suganuma, Jerry L. Workman · 2018 · Annual Review of Biochemistry
- Above the Epitranscriptome: RNA Modifications and Stem Cell IdentityFrancesco Morena, Chiara Argentati, Martina Bazzucchi, Carla Emiliani, Sabata Martino · 2018 · Genes
- The epigenetics of inflammaging: The contribution of age-related heterochromatin loss and locus-specific remodelling and the modulation by environmental stimuliChristine Nardini, Jean‐François Moreau, Noémie Gensous, Francesco Ravaioli, Paolo Garagnani, Maria Giulia Bacalini · 2018 · Seminars in Immunology
- Untitled work2023 · 10.1016/j.celrep.2023.112593
- Cardiac Aging Is Promoted by Pseudohypoxia Increasing p300-Induced GlycolysisSimone Serio, Christina Pagiatakis, Elettra Musolino, Arianna Felicetta, Pierluigi Carullo, Javier Laura Francés, Laura Papa, Giacomo Rozzi, Nicolò Salvarani, Michele Miragoli et al. · 2023 · Circulation Research
- Genome-wide transcriptomics of aging in the rotifer Brachionus manjavacas, an emerging model systemKristin Elizabeth Gribble, David B. Mark Welch · 2017 · BMC Genomics
- Slowing Down Ageing: The Role of Nutrients and Microbiota in Modulation of the EpigenomeAgnieszka Gadecka, Anna Bielak-Żmijewska · 2019 · Nutrients
- Epigenetic N6-methyladenosine modification of RNA and DNA regulates cancerZhixian Liang, Reilly L. Kidwell, Haijing Deng, Qi Xie · 2020 · Cancer Biology and Medicine
- Oxysterols are potential physiological regulators of ageingPhilippe de Médina, Sandrine Silvente‐Poirot, Marc Poirot · 2022 · Ageing Research Reviews
- Dietary Polyphenols as Anti-Aging Agents: Targeting the Hallmarks of AgingYing Liu, Minglv Fang, Xiaohui Tu, Xueying Mo, Lu Zhang, Binrui Yang, Feijie Wang, Young‐Bum Kim, Cheng Huang, Liang Chen et al. · 2024 · Nutrients
- Stabilization of telomere by the antioxidant property of polyphenols: Anti-aging potentialMasomeh Maleki, Nafiseh Khelghati, Forough Alemi, Mahtab Bazdar, Zatollah Asemi, Maryam Majidinia, Alireza Sadeghpoor, Ata Mahmoodpoor, Farhad Jadidi‐Niaragh, Nilofar Targhazeh et al. · 2020 · Life Sciences
- The aging proteostasis decline: From nematode to humanAnatoly Meller, Reut Shalgi · 2021 · Experimental Cell Research
- Elevated H3K27ac in aged skeletal muscle leads to increase in extracellular matrix and fibrogenic conversion of muscle satellite cellsJiajian Zhou, Karl Kam Hei So, Yuying Li, Yang Li, Jie Yuan, Yingzhe Ding, Fengyuan Chen, Yile Huang, Jin Liu, Wayne Lee et al. · 2019 · Aging Cell
- Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in miceJung Eun Lee, Hye‐Jin Kwon, Juli Choi, Ji-Seon Seo, Pyung‐Lim Han · 2020 · Communications Biology
- Senescence Elicits Stemness: A Surprising Mechanism for Cancer RelapseZhixun Dou, Shelley L. Berger · 2018 · Cell Metabolism
- The role and molecular mechanism of epigenetics in cardiac hypertrophyHao Chuan Lei, Jiahui Hu, Kaijun Sun, Danyan Xu · 2020 · Heart Failure Reviews