Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

Baar, Marjolein P., Brandt, Renata M.C., Putavet, Diana A., Klein, Julian D.D., Derks, Kasper W.J., Bourgeois, Benjamin R.M., Stryeck, Sarah, Rijksen, Yvonne +13 more·2017·Cell
DOI 10.1016/j.cell.2017.02.031

Cited by (1,000)

Items 601–700 of 1,000

  1. Nano-Based Theranostic Tools for the Detection and Elimination of Senescent Cells
    Jagoda Adamczyk‐Grochala, Anna Lewińska · 2020 · Cells
  2. Can Blood-Circulating Factors Unveil and Delay Your Biological Aging?
    Natalia Rybtsova, Tatiana Nikolaevna Berezina, Alexander Kagansky, Рыбцов Станислав Александрович · 2020 · Biomedicines
  3. Anti-Aging Effects of Anthocyanin Extracts of Sambucus canadensis Caused by Targeting Mitochondrial-Induced Oxidative Stress
    Xiaoqing Hu, Yimeng Yang, Shi Tang, Qiuyan Chen, Meiyu Zhang, Jiaoyan Ma, Jianchun Qin, Huimei Yu · 2023 · International Journal of Molecular Sciences
  4. Knockdown of angiopoietin-like 2 induces clearance of vascular endothelial senescent cells by apoptosis, promotes endothelial repair and slows atherogenesis in mice
    Laurie Caland, Pauline Labbé, Maya Mamarbachi, Louis Robert Villeneuve, Gerardo Ferbeyre, Pierre‐Emmanuel Noly, Michel Carrier, Nathalie Thorin‐Trescases, Éric Thorin · 2019 · Aging
  5. Regulation of cellular senescence by microRNAs
    Ma, Xingjie, Zheng, Qingbin, Zhao, Guangming, Yuan, Wenjie, Liu, Weili · 2020 · Mechanisms of Ageing and Development
  6. Approaches towards Longevity: Reprogramming, Senolysis, and Improved Mitotic Competence as Anti-Aging Therapies
    Sofia Melo Pereira, Rui Ribeiro, Elsa Logarinho · 2019 · International Journal of Molecular Sciences
  7. Age-related dysfunction of the DNA damage response in intestinal stem cells
    Koichiro Watanabe, Yasuaki Ikuno, Yumi Kakeya, Shinsuke Ikeno, Hitomi Taniura, Masayoshi Kurono, Keito Minemori, Yu Katsuyama, Hayato Naka-Kaneda · 2019 · Inflammation and Regeneration
  8. SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs
    Heike Fuhrmann‐Stroissnigg, Fernando Enrique Santiago, Diego Grassi, Yuanyuan Ling, Laura J. Niedernhofer, Paul D. Robbins · 2019 · Journal of Visualized Experiments
  9. Innate Immune Signaling Contributes to Tubular Cell Senescence in the Glis2 Knockout Mouse Model of Nephronophthisis
    Heng Jin, Yan Zhang, Dingxiao Liu, Shan Shanshan Wang, Qiong J. Ding, Prerna Rastogi, Madison Purvis, Angela Wang, Sarah El-Hadi, Chongyu Ren et al. · 2019 · American Journal Of Pathology
  10. Fate of Hematopoiesis During Aging. What Do We Really Know, and What are its Implications?
    Hal E. Broxmeyer, Yan Liu, Reuben Kapur, Christie M. Orschell, Arafat Aljoufi, James P. Ropa, Thao Le Phuong Trinh, Sarah S. Burns, Maegan L. Capitano · 2020 · Stem Cell Reviews and Reports
  11. Distinct types of stem cell divisions determine organ regeneration and aging in hair follicles
    Hiroyuki Matsumura, Nan Liu, Daisuke Nanba, Shizuko Ichinose, Aki Takada, Sotaro Kurata, Hironobu Morinaga, Yasuaki Mohri, Adèle De Arcangelis, Shigeo Ohno et al. · 2021 · Nature Aging
  12. Promises and challenges of senolytics in skin regeneration, pathology and ageing
    Vera Pils, Nadja Ring, Karla Valdivieso, Ingo Lämmermann, Флориан Грубер, Markus Schosserer, Johannes Grillari, Mikolaj B. Ogrodnik · 2021 · Mechanisms of Ageing and Development
  13. Senotherapeutic-like effect of Silybum marianum flower extract revealed on human skin cells
    Jieun Woo, Seoungwoo Shin, Eunae Cho, Dehun Ryu, David Garandeau, Hanane Chajra, Mathilde Fréchet, Deokhoon Park, Eunsun Jung · 2021 · PLoS ONE
  14. Therapeutic Antiaging Strategies
    Shailendra Kumar Mishra, Vyshnavy Balendra, Josephine Esposto, Ahmad A. Obaid, Ricardo Benjamin Maccioni, Niraj Kumar Jha, George L. Perry, Mahmoud Moustafa, Mohammed Al-Shehri, Mahendra Pratap Singh et al. · 2022 · Biomedicines
  15. The Power Behind the Throne: Senescence and the Hallmarks of Cancer
    Matthew Hoare, Masashi Narita · 2017 · Annual Review of Cancer Biology
  16. Aging as a loss of morphostatic information: A developmental bioelectricity perspective
    Léo Pio‐Lopez, Michael G. Levin · 2024 · Ageing Research Reviews
  17. Hypoxia and aging: molecular mechanisms, diseases, and therapeutic targets
    Ayesha Nisar, Sawar Khan, Wen Li, Li Hu, Priyadarshani Nadeeshika Samarawickrama, Naheemat Modupeola Gold, Meiting Zi, Sardar Azhar Mehmood, Jiarong Miao, Yonghan He · 2024 · MedComm
  18. Senolytics: charting a new course or enhancing existing anti-tumor therapies?
    Konrad Czajkowski, Mariola Herbet, Marek Murias, Iwona Piątkowska‐Chmiel · 2024 · Cellular Oncology
  19. Replicative senescent human cells possess altered circadian clocks with a prolonged period and delayed peak-time
    Rezwana Ahmed, Atsushige Ashimori, Satoshi Iwamoto, Takaaki Matsui, Yasukazu Nakahata, Yasumasa Bessho · 2019 · Aging
  20. Hepatic flow is an intraoperative predictor of early allograft dysfunction in whole-graft deceased donor liver transplantation: An observational cohort study
    Pablo Lozano Lominchar, Maitane Igone Orue-Echebarria, Lorena Martín, Cristina Julia Lisbona, María Magdalena Salcedo, Luis Olmedilla, Hemant Sharma, Jose Manuel Asencio, José Ángel López-Baena · 2019 · World Journal of Hepatology
  21. Rising from the ashes: cellular senescence in regeneration
    Hannah Walters, Maximina Hee Yun · 2020 · Current Opinion in Genetics & Development
  22. Cellular communication network 2 (connective tissue growth factor) aggravates acute DNA damage and subsequent DNA damage response-senescence-fibrosis following kidney ischemia reperfusion injury
    Floris A. Valentijn, Sebastiaan N. Knoppert, Laura Márquez‐Expósito, Raúl R. Rodrigues-Díez, Georgios Pissas, Jiaqi Tang, Lucía Tejedor-Santamaria, Roel Broekhuizen, Rohan Samarakoon, Theodoros Eleftheriadis et al. · 2022 · Kidney International
  23. YTHDF2 Regulates Macrophage Polarization through NF-κB and MAPK Signaling Pathway Inhibition or p53 Degradation
    Luhui Cai, Di Li, Zhihui Feng, Xiaofei Gu, Qiong Xu, Qimeng Li · 2022 · Disease Markers
  24. Metformin ameliorates 5-fluorouracil-induced intestinal injury by inhibiting cellular senescence, inflammation, and oxidative stress
    Jing Xia, Jun Chen, Manoj Kumar Vashisth, Yuchen Ge, Qianlong Dai, Siyue He, Yi-ling Shi, Xiaobo Wang · 2022 · International Immunopharmacology
  25. Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease
    Tinka Vidović, Collin Y. Ewald · 2022 · Frontiers in Aging
  26. Disrupted Binding of Cystathionine γ-Lyase to p53 Promotes Endothelial Senescence
    Jiong Hu, Matthias S. Leisegang, Mario Looso, Maria-Kyriaki Drekolia, Janina Wittig, Janina Mettner, Christina Karantanou, Anastasia Kyselova, Gabrijela Dumbović, Xiaoming Li et al. · 2023 · Circulation Research
  27. Targeting DNA damage in ageing: towards supercharging DNA repair
    Arturo Bujarrabal-Dueso, George A. Garinis, Paul D. Robbins, Jan Vijg, Björn Schumacher · 2025 · Nature Reviews Drug Discovery
  28. Immunopharmacology of senescence: targeting the senescence-associated secretory phenotype (SASP)—a mechanism-based review
    Poonam Sahu, Trilochan Satapathy · 2025 · Inflammopharmacology
  29. The role of cellular senescence in cardiovascular disease
    Chengying Xu, Zhimei Qiu, Qing Guo, Yuerong Huang, Yongchao Zhao, Ranzun Zhao · 2025 · Cell Death Discovery
  30. Antiaging Vaccines Targeting Senescent Cells
    Andrew R. Mendelsohn, James W. Larrick · 2022 · Rejuvenation Research
  31. Cellular senescence induction leads to progressive cell death via the INK4a‐RB pathway in naked mole‐rats
    Yoshimi Kawamura, Kaori Oka, Takashi Semba, Mayuko Takamori, Yuki Sugiura, Riyo Yamasaki, Yusuke Suzuki, Takeshi Chujo, Mari Nagase, Yuki Oiwa et al. · 2023 · The EMBO Journal
  32. Mechanistic regulation of FOXO transcription factors in the nucleus
    Xiaowei Guo, Kai Peng, Yanwen He, Lei Xue · 2024 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  33. Anti-senescence therapies: a new concept to address cardiovascular disease
    Stevan D. Stojanović, Thomas Thum, Johann K Bauersachs · 2025 · Cardiovascular Research
  34. Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT 1 activity and antioxidant gene expression in mouse cells
    Fiqri Dizar Khaidizar, Yasukazu Nakahata, Akira Kume, Kyosuke Sumizawa, Kenji Kohno, Takaaki Matsui, Yasumasa Bessho · 2017 · Genes to Cells
  35. Recent insights into the cellular and molecular determinants of aging
    Linhao Ruan, Xi Zhang, Rong Li · 2018 · Journal of Cell Science
  36. SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells
    Claudio A. Valenzuela, Ricardo Quintanilla, Alexandra Olate‐Briones, Whitney Venturini, Daniel Mancilla, Ángel Cayo, Rodrigo Moore‐Carrasco, Nelson E. Brown · 2019 · International Journal of Molecular Sciences
  37. Cell senescence: basic mechanisms and the need for computational networks in vascular ageing
    Véronique Regnault, Pascal Challande, Florence Pinet, Zhenlin Li, Patrick J. Lacolley · 2020 · Cardiovascular Research
  38. Kidney inflammaging is promoted by CCR2+ macrophages and tissue-derived micro-environmental factors
    Lise Lefèvre, Jason S. Iacovoni, Hélène Martini, Julie Bellière, Damien Maggiorani, Marianne Dutaur, Dimitri J. Marsal, Pauline Decaunes, Nathalie Pizzinat, Jeanne Mialet‐Perez et al. · 2020 · Cellular and Molecular Life Sciences
  39. Revelations About Aging and Disease from Unconventional Vertebrate Model Organisms
    Yang Zhao, Andrei Seluanov, Vera A. Gorbunova · 2021 · Annual Review of Genetics
  40. Senescence in HBV-, HCV- and NAFLD- Mediated Hepatocellular Carcinoma and Senotherapeutics: Current Evidence and Future Perspective
    Vassilis G. Giannakoulis, Peter Dubovan, Eleni Papoutsi, Agapi Kataki, John S. Koskinas · 2021 · Cancers
  41. Apoptotic vesicles rejuvenate mesenchymal stem cells via Rab7-mediated autolysosome formation and alleviate bone loss in aging mice
    Fangcao Lei, Zhiqing Huang, Qianmin Ou, Jiaqi Li, Manqing Liu, Lan Ma, Lingping Tan, Zhengmei Lin, Xiaoxing Kou · 2022 · Nano Research
  42. From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs
    Valentin L’Hôte, Carl Mann, Jean‐Yves Thuret · 2022 · Open Biology
  43. Counteracting Immunosenescence—Which Therapeutic Strategies Are Promising?
    Christoph Hieber, Stephan Grabbe, Matthias Bros · 2023 · Biomolecules
  44. Methyl-CpG Binding Protein 2 in Alzheimer Dementia
    Baeksun Kim, Yunjung Choi, Hye-Sun Kim, Heh‐In Im · 2019 · International Neurourology Journal
  45. Revolutionizing Diabetic Foot Ulcer Care: The Senotherapeutic Approach
    Guiqin Zhang, Priyadarshani Nadeeshika Samarawickrama, Li Gui, Yuan Ma, Mei Cao, Hong Zhu, Wei Li, Honglin Yang, Kecheng Li, Yang Yang et al. · 2024 · Aging and Disease
  46. A Senomorphlytic Three‐Drug Combination Discovered in Salsola collina for Delaying Aging Phenotypes and Extending Healthspan
    Jiqun Wang, Wenwen Liu, Yunyuan Huang, Guangwei Wang, Xiaobo Guo, Donglei Shi, Tianyue Sun, Chao‐Jiang Xiao, Chao Zhang, Bei Jiang et al. · 2024 · Advanced Science
  47. The dual role of cellular senescence in human tumor progression and therapy
    Liang Ma, Jie Yu, Yidian Fu, Xiaoyu He, Shengfang Ge, Renbing Jia, Ai Zhuang, Zhi Hua Yang, Xianqun Fan · 2024 · MedComm
  48. Understanding and targeting senescence in kidney disease
    Lucie Chanvillard, Tilly Mason, David A. Ferenbach · 2025 · Clinical Kidney Journal
  49. Pharmacological effects, molecular mechanisms and strategies to improve bioavailability of curcumin in the treatment of neurodegenerative diseases
    Gang Wang, Xueyuan Zhou, Xiaoyan Pang, Ke Ma, Lü Li, Yuexin Song, Dongxia Hou, Xiaohua Wang · 2025 · Frontiers in Pharmacology
  50. Remodeling of senescent macrophages in synovium alleviates trauma- and aging-induced osteoarthritis
    Yuhang Liu, Jianan Duan, Yifan Dang, Ruihan Hao, Hui Wang, Echuan Tan, Ruijue Wang, Yuhan Li, Song Zhang, Yuanchi Wang et al. · 2025 · Bioactive Materials
  51. c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors
    Kevin C. Flanagan, Elise Alspach, Ermira Pazolli, Shankar Prasad Parajuli, Qihao Ren, Laura Arthur, ROBERTO C. TAPIA-CONYER, Sheila A. Stewart · 2017 · Oncotarget
  52. Overcoming Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutated Tumours
    Emily L. Paton, Jacqueline A. Turner, Isabel R. Schlaepfer · 2020 · Journal of Oncology
  53. Senolytics: Targeting Senescent Cells for Age-Associated Diseases
    Iman M. Al‐Naggar, George A. Kuchel, Ming Xu · 2020 · Current Molecular Biology Reports
  54. Recent advances in targeting protein kinases and pseudokinases in cancer biology
    Kristina Riegel, Parthiban Vijayarangakannan, Petros Kechagioglou, Katarzyna Bogucka, Krishnaraj Rajalingam · 2022 · Frontiers in Cell and Developmental Biology
  55. Role of Forkhead Box O Transcription Factors in Oxidative Stress-Induced Chondrocyte Dysfunction: Possible Therapeutic Target for Osteoarthritis?
    Rikang Wang, Shuai Zhang, Rahul Previn, Di Chen, Yi Jin, Guangqian Zhou · 2018 · International Journal of Molecular Sciences
  56. Out with the old, in with the new: senescence in development
    Czarkwiani, Anna, Yun, Maximina H · 2018 · Current Opinion in Cell Biology
  57. Understanding cellular senescence: pathways involved, therapeutics and longevity aiding
    Ashish Kumar, Kavitha Thirumurugan · 2023 · Cell Cycle
  58. SKN‐1/NRF2 upregulation by vitamin A is conserved from nematodes to mammals and is critical for lifespan extension in Caenorhabditis elegans
    Chaweewan Sirakawin, Dongfa Lin, Ziyue Zhou, Xiaoxin Wang, Rhianne Kelleher, Shangyuan Huang, Weimiao Long, Andre Pires‐daSilva, Yu Liu, Jingjing Wang et al. · 2023 · Aging Cell
  59. The Potential Role and Therapeutic Relevance of Cellular Senescence in Skeletal Pathophysiology
    Bo Li, Ping Lyu, Jinru Tang, Jingya Li, Takehito Ouchi, Yi Fan, Zhihe Zhao, Longjiang Li · 2024 · The Journals of Gerontology Series A
  60. Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases
    Said Ali Ozdemir, Md Imam Faizan, Gagandeep Kaur, Sadiya Bi Shaikh, Khursheed Ul Islam, Irfan Rahman · 2025 · International Journal of Molecular Sciences
  61. Still Living Better through Chemistry: An Update on Caloric Restriction and Caloric Restriction Mimetics as Tools to Promote Health and Lifespan
    Carla Almendáriz-Palacios, Darrell D. Mousseau, Christopher H. Eskiw, Zoe E. Gillespie · 2020 · International Journal of Molecular Sciences
  62. Senescence: A program in the road to cell elimination and cancer
    Moiseeva, Olga, Guillon, Jordan, Ferbeyre, Gerardo · 2022 · Seminars in Cancer Biology
  63. Anti-aging effects of chlorpropamide depend on mitochondrial complex-II and the production of mitochondrial reactive oxygen species
    Zhifan Mao, Wenwen Liu, Yunyuan Huang, Tianyue Sun, Keting Bao, Jiali Feng, Alexey Moskalev, Zelan Hu, Jian Li · 2021 · Acta Pharmaceutica Sinica B
  64. A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells
    Rupesh S. Patel, Rodrigo Romero, Emma V. Watson, Anthony C. T. Liang, Megan L. Burger, Peter M.K. Westcott, Kim L. Mercer, Roderick Terry Bronson, Eric C. Wooten, Arjun J. Bhutkar et al. · 2022 · Nature Communications
  65. The aging of the immune system and its implications for transplantation
    Kathryn E. McGovern, Sandip Ashok Sonar, Makiko Watanabe, Christopher P. Coplen, Christine M. Bradshaw, Janko Nikolich‐Žugich · 2023 · GeroScience
  66. Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells
    Ana Lázaro-Carrillo, Macarena Calero, Antonio Aires, Aitziber L. Cortajarena, Bruno M. Simões, Alfonso Latorre, Álvaro Somoza, Robert B. Clarke, Rodolfo Miranda, Ángeles Villanueva · 2020 · Cancers
  67. Extension of Maximal Lifespan and High Bone Marrow Chimerism After Nonmyeloablative Syngeneic Transplantation of Bone Marrow From Young to Old Mice
    Kovina, Marina V., Karnaukhov, Alexey V., Krasheninnikov, Mikhail E., Kovin, Artem L., Gazheev, Sarul T., Sergievich, Larisa A., Karnaukhova, Elena V., Bogdanenko, Elena V., Balyasin, Maxim V., Khodarovich, Yury M. et al. · 2019 · Frontiers in Genetics
  68. Exploiting pivotal mechanisms behind the senescence-like cell cycle arrest in cancer
    Seyede Nazanin Zarneshan, Sajad Fakhri, Gabrielle Bachtel, Anupam Bishayee · 2023 · Advances in protein chemistry and structural biology
  69. Beetroot (Beta vulgaris) extract exerts an antibacterial effect by inducing apoptosis-like death in Bacillus cereus
    Shaoying Gong, Chaoqin Jiao, Biqi Liu, Wenxuan Qu, Ling Jun Guo, Yujun Jiang · 2023 · Journal of Functional Foods
  70. Cellular senescence and frailty: a comprehensive insight into the causal links
    Serena Marcozzi, Giorgia Bigossi, Maria Elisa Giuliani, Robertina Giacconi, Francesco Piacenza, Maurizio Cardelli, Dario Brunetti, Agnese Segala, Alessandra Valerio, Enzo Nisoli et al. · 2023 · GeroScience
  71. Non‐canonical ATM/MRN activities temporally define the senescence secretory program
    Nicolas Malaquin, Audrey Carrier-Leclerc, Aurélie Martinez, Mireille Dessureault, Sabrina Ghadaouia, Jean‐Philippe Coppé, Stéphanie Nadeau, Guillaume Cardin, Judith Campisi, Françis Rodier · 2020 · EMBO Reports
  72. FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase
    Jessica Voisin, Francesca Farina, Swati B. Naphade, Morgane Fontaine, Kizito‐Tshitoko Tshilenge, Carlos Galicia Aguirre, Alejandro Lopez‐Ramirez, Julia Dancourt, Aurélie Ginisty, Satish Sasidharan Nair et al. · 2020 · Aging Cell
  73. Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence‐associated secretory phenotype
    Ryan Wallis, Nataša Josipović, Hannah Mizen, Arturo Robles‐Tenorio, Eleanor J. Tyler, Argyris Papantonis, Cleo L. Bishop · 2021 · Journal of Extracellular Vesicles
  74. The tumor suppression theory of aging
    Alexander Martin Wolf · 2021 · Mechanisms of Ageing and Development
  75. Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging
    Jian Chen, Zhexiang Fan, Decong Zhu, Yilong Guo, Ke Ye, Damao Dai, Zhi Jian Guo, Zhiqi Hu, Yong Miao, Qian Qu · 2021 · Frontiers in Cell and Developmental Biology
  76. Integrin β3 Induction Promotes Tubular Cell Senescence and Kidney Fibrosis
    Li Shen, Song Jiang, Qingyan Zhang, Bo Ram Jin, Daoyuan Lv, Wenju Li, Min Zhao, Chunming Jiang, Chunsun Dai, Zhihong Liu · 2021 · Frontiers in Cell and Developmental Biology
  77. Senotherapeutics in Cancer and HIV
    Laura Sánchez-Díaz, Asunción Espinosa-Sánchez, José Ramón Blanco, Amancio Carnero · 2022 · Cells
  78. Telomere Maintenance and the cGAS-STING Pathway in Cancer
    Hiroshi Ebata, Tze Mun Loo, Akiko Takahashi · 2022 · Cells
  79. Senotherapeutics for mesenchymal stem cell senescence and rejuvenation
    Pooi‐Fong Wong, Dharmani Devi Murugan, Thamil Selvee Ramasamy · 2022 · Drug Discovery Today
  80. Mechanisms of Senescence and Anti-Senescence Strategies in the Skin
    Evangelia K. Konstantinou, Eliane Longange, Gürkan Kaya · 2024 · Biology
  81. Senescence chips for ultrahigh‐throughput isolation and removal of senescent cells
    Yuchao Chen, Pan Mao, Antoine M. Snijders, Daojing Wang · 2018 · Aging Cell
  82. Raman fingerprints as promising markers of cellular senescence and aging
    Lisa Liendl, Johannes Grillari, Markus Schosserer · 2019 · GeroScience
  83. Therapy-Induced Senescence: Novel Approaches for Markers Identification
    Francesco Pacifico, Fulvio Magni, Antonio Leonardi, Elvira Crescenzi · 2024 · International Journal of Molecular Sciences
  84. FOXOs and their roles in acute and chronic neurological disorders
    Yasin Asadi, Rozenn K. Moundounga, Anand Chakroborty, Augustina Potokiri, Hongmin Wang · 2025 · Frontiers in Molecular Biosciences
  85. The use of geroprotectors to prevent multimorbidity: Opportunities and challenges
    Samir Morsli, Ilaria Bellantuono · 2020 · Mechanisms of Ageing and Development
  86. The role of alternative oxidase in plant hypersensitive response
    Muhammad Suleman, M. Ma, G. Ge, D. Hua, H. Li · 2021 · Plant Biology
  87. High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice
    Jamil Nehme, Dengbao Yang, Abdullah Altulea, Marta Varela-Eirín, Lu Wang, Sumei Hu, Yingga Wu, Jacques Togo, Chaoqun Niu, John Roger Speakman et al. · 2021 · FEBS Journal
  88. The interaction between cellular senescence and chronic kidney disease as a therapeutic opportunity
    Jing-Li Zhao, Xiao-Hui Qiao, Jianhua Mao, Fei Liu, Haidong Fu · 2022 · Frontiers in Pharmacology
  89. SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer
    Aravinda‐Bharathi Ramakrishnan, Peter E. Burby, Kavya Adiga, Ken M. Cadigan · 2022 · Journal of Biological Chemistry
  90. Peptide mediated therapy in fibrosis: Mechanisms, advances and prospects
    Xun Ye, Jinhu Li, Zibo Liu, Xue Sun, Daneng Wei, Linjiang Song, Chunjie Wu · 2022 · Biomedicine & Pharmacotherapy
  91. New Insights into the Genetics and Epigenetics of Aging Plasticity
    Jie Zhang, Shixiao Wang, Baohua Liu · 2023 · Genes
  92. Involvement of Bcl-2 Family Proteins in Tetraploidization-Related Senescence
    Daniel Barriuso, Lucia Alvarez-Frutos, Lucía G. Gutiérrez, Omar Motiño, Guido Kroemer, Roberto Palacios, Laura Senovilla · 2023 · International Journal of Molecular Sciences
  93. New Horizons in cellular senescence for clinicians
    Miles D. Witham, Antoneta Granic, Satomi Miwa, João F. Passos, Gavin David Richardson, Avan Aihie Sayer · 2023 · Age and Ageing
  94. Quercetin induces senolysis of doxorubicin-induced senescent fibroblasts by reducing autophagy, preventing their pro-tumour effect on osteosarcoma cells
    Elisa Bientinesi, Sara Ristori, Matteo Lulli, Daniela Monti · 2024 · Mechanisms of Ageing and Development
  95. Rejuvenation by Therapeutic Elimination of Senescent Cells
    Paul Krimpenfort, Anton J. M. Berns · 2017 · Cell
  96. Jumonji C Demethylases in Cellular Senescence
    Kelly E. Leon, Katherine M. Aird · 2019 · Genes
  97. Senescent cells: A new Achilles’ heel to exploit for cancer medicine?
    Boyi Zhang, Eric W.‐F. Lam, Yu Sun · 2018 · Aging Cell
  98. LncRNA GUARDIN suppresses cellular senescence through a LRP130‐PGC1α‐FOXO4‐p21‐dependent signaling axis
    Xuedan Sun, Rick Francis Thorne, Xu Dong Zhang, Miao He, Jinming Li, Shanshan Feng, Xiaoying Liu, Mian Wu · 2020 · EMBO Reports
  99. Transcription Blockage by DNA Damage in Nucleotide Excision Repair-Related Neurological Dysfunctions
    Kajitani, Gustavo Satoru, Nascimento, Livia Luz de Souza, Neves, Maira Rodrigues de Camargo, Leandro, Giovana da Silva, Garcia, Camila Carrião Machado, Menck, Carlos Frederico Martins · 2021 · Seminars in Cell & Developmental Biology
  100. Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders
    Tábatha de Oliveira Silva, Guilherme Lunardon, Caroline Antunes Lino, Amanda De Almeida Silva, Shiju Zhang, Maria Cláudia Irigoyen, Yao Wei Lu, John D. Mably, Maria Luiza Morais Barreto‐Chaves, Dazhi Wang et al. · 2024 · Molecular Metabolism