The Human Transcription Factors

Cited by (135)

Items 101–135 of 135

  1. High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer
    Pierce, Sarah E., Granja, Jeffrey M., Greenleaf, William J. · 2021 · Nature Communications
  2. The Role of Nutrition in COVID-19 Susceptibility and Severity of Disease: A Systematic Review
    James, Philip T, Ali, Zakari, Armitage, Andrew E, Bonell, Ana, Cerami, Carla, Drakesmith, Hal, Jobe, Modou, Jones, Kerry S, Liew, Zara, Moore, Sophie E et al. · 2021 · The Journal of Nutrition
  3. Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis
    Gillespie, Mark A., Palii, Carmen G., Sanchez-Taltavull, Daniel, Shannon, Paul, Longabaugh, William J.R., Downes, Damien J., Sivaraman, Karthi, Espinoza, Herbert M., Hughes, Jim R., Price, Nathan D. et al. · 2020 · Molecular Cell
  4. SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks
    González-Blas, Carmen Bravo, De Winter, Seppe, Hulselmans, Gert, Hecker, Nikolai, Matetovici, Irina, Christiaens, Valerie, Poovathingal, Suresh, Wouters, Jasper, Aibar, Sara, Aerts, Stein · 2022
  5. A prenatal skin atlas reveals immune regulation of human skin morphogenesis
    Gopee, Nusayhah Hudaa, Winheim, Elena, Olabi, Bayanne, Admane, Chloe, Foster, April Rose, Huang, Ni, Botting, Rachel A., Torabi, Fereshteh, Sumanaweera, Dinithi, Le, Anh Phuong et al. · 2024 · Nature
  6. Hold out the genome: a roadmap to solving the cis-regulatory code
    de Boer, Carl G., Taipale, Jussi · 2024 · Nature
  7. Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer
    Klomp, Jennifer E., Diehl, J. Nathaniel, Klomp, Jeffrey A., Edwards, A. Cole, Yang, Runying, Morales, Alexis J., Taylor, Khalilah E., Drizyte-Miller, Kristina, Bryant, Kirsten L., Schaefer, Antje et al. · 2024 · Science
  8. Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs
    Janssens, Derek H., Wu, Steven J., Sarthy, Jay F., Meers, Michael P., Myers, Carrie H., Olson, James M., Ahmad, Kami, Henikoff, Steven · 2018 · Epigenetics & Chromatin
  9. Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk
    Reshef, Yakir A., Finucane, Hilary K., Kelley, David R., Gusev, Alexander, Kotliar, Dylan, Ulirsch, Jacob C., Hormozdiari, Farhad, Nasser, Joseph, O’Connor, Luke, van de Geijn, Bryce et al. · 2018 · Nature Genetics
  10. Development of compact transcriptional effectors using high-throughput measurements in diverse contexts
    Tycko, Josh, Van, Mike V., Aradhana, DelRosso, Nicole, Ye, Hanrong, Yao, David, Valbuena, Raeline, Vaughan-Jackson, Alun, Xu, Xiaoshu, Ludwig, Connor et al. · 2025 · Nature Biotechnology
  11. Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation
    Lin, Lin, DeMartino, Jeff, Wang, Daisong, van Son, Gijs J. F., van der Linden, Reinier, Begthel, Harry, Korving, Jeroen, Andersson-Rolf, Amanda, van den Brink, Stieneke, Lopez-Iglesias, Carmen et al. · 2023 · Science
  12. Improving prediction performance of general protein language model by domain-adaptive pretraining on DNA-binding protein
    Zeng, Wenwu, Dou, Yutao, Pan, Liangrui, Xu, Liwen, Peng, Shaoliang · 2024 · Nature Communications
  13. Identification of AP-1 as a Critical Regulator of Glutathione Peroxidase 4 (GPX4) Transcriptional Suppression and Acinar Cell Ferroptosis in Acute Pancreatitis
    Ma, Xiaojie, Dong, Xiaowu, Xu, Yao, Ma, Nan, Wei, Mei, Xie, Xiaochun, Lu, Yingying, Cao, Wangsen, Lu, Guotao, Li, Weiqin · 2022 · Antioxidants
  14. T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system
    Mohan, Rajiv A., Bosada, Fernanda M., van Weerd, Jan H., van Duijvenboden, Karel, Wang, Jianan, Mommersteeg, Mathilda T. M., Hooijkaas, Ingeborg B., Wakker, Vincent, de Gier-de Vries, Corrie, Coronel, Ruben et al. · 2020 · Proceedings of the National Academy of Sciences
  15. Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells
    Shan, Feng, Cillo, Anthony R., Cardello, Carly, Yuan, Daniel Y., Kunning, Sheryl R., Cui, Jian, Lampenfeld, Caleb, Williams, Asia M., McDonough, Alexandra P., Pennathur, Arjun et al. · 2023 · Science Immunology
  16. Design principles of cell-state-specific enhancers in hematopoiesis
    Frömel, Robert, Rühle, Julia, Bernal Martinez, Aina, Szu-Tu, Chelsea, Pacheco Pastor, Felix, Martinez-Corral, Rosa, Velten, Lars · 2025 · Cell
  17. Pharmacological Restriction of Genomic Binding Sites Redirects PU.1 Pioneer Transcription Factor Activity
    Taylor, Samuel J., Stauber, Jacob, Bohorquez, Oliver, Tatsumi, Goichi, Kumari, Rajni, Chakraborty, Joyeeta, Bartholdy, Boris A., Schwenger, Emily, Sundaravel, Sriram, Farahat, Abdelbasset A. et al. · 2024 · Nature Genetics
  18. A proteomic platform to identify off-target proteins associated with therapeutic modalities that induce protein degradation or gene silencing
    Liu, Xin, Zhang, Ye, Ward, Lucas D., Yan, Qinghong, Bohnuud, Tanggis, Hernandez, Rocio, Lao, Socheata, Yuan, Jing, Fan, Fan · 2021 · Scientific Reports
  19. Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif
    Ru, Wenwen, Koga, Tomoyuki, Wang, Xiaoyang, Guo, Qiong, Gearhart, Micah D., Zhao, Shidong, Murphy, Mark, Kawakami, Hiroko, Corcoran, Dylan, Zhang, Jiahai et al. · 2022 · Journal of Biological Chemistry
  20. Canalizing cell fate by transcriptional repression
    Lim, Bryce, Domsch, Katrin, Mall, Moritz, Lohmann, Ingrid · 2024 · Molecular Systems Biology
  21. Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
    Viner, Coby, Ishak, Charles A., Johnson, James, Walker, Nicolas J., Shi, Hui, Sjöberg-Herrera, Marcela K., Shen, Shu Yi, Lardo, Santana M., Adams, David J., Ferguson-Smith, Anne C. et al. · 2016
  22. Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis
    Lim, Bryce, Kamal, Aryan, Gomez Ramos, Borja, Adrian Segarra, Juan M., Ibarra, Ignacio L., Dignas, Lennart, Kindinger, Tim, Volz, Kai, Rahbari, Mohammad, Rahbari, Nuh et al. · 2025 · Nature Genetics
  23. Revisiting Epigenetics Fundamentals and Its Biomedical Implications
    Meza-Menchaca, Thuluz, Albores-Medina, Arnulfo, Heredia-Mendez, Alma Jaqueline, Ruíz-May, Eliel, Ricaño-Rodríguez, Jorge, Gallegos-García, Verónica, Esquivel, Adriana, Vettoretti-Maldonado, Giancarlo, Campos-Parra, Alma D. · 2024 · International Journal of Molecular Sciences
  24. Phosphorylated ATF1 at Thr184 promotes metastasis and regulates MMP2 expression in gastric cancer
    Li, Tong, Cao, Huiyuan, Wu, Sa, Zhong, Peimin, Ding, Jie, Wang, Jing, Wang, Fangfang, He, Zhiwei, Huang, Guo-Liang · 2022 · Journal of Translational Medicine
  25. Engineered retrons generate genome-independent protein-binding DNA for cellular control
    Lee, Geonhu, Kim, Jongmin · 2023
  26. 20E-induced Kr-h1 expression facilitates developmental transitions depending on chromosome accessibility of BR-C enhancers
    Long, Shihui, Qiu, Yongyu, Lin, Tong, Huang, Shumin, Zhang, Wenhao, Liu, Suning, Tian, Ling, Palli, Subba R., Li, Sheng, Li, Kang · 2025 · Proceedings of the National Academy of Sciences
  27. A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform
    Jain, Siddhant U., Williamson, Kaylyn E., Ying, Alexander W., Turner, Aasha M., Jiang, Ruidong Jerry, Raval, Shaunak, So, Kevin, Allison, Maxwell J., Sankar, Akshay, Sáme Guerra, Daniel D. et al. · 2026 · Science
  28. Cardiac differentiation roadmap for analysis of plasticity and balanced lineage commitment
    Snabel, Rebecca R., Cofiño-Fabrés, Carla, Baltissen, Marijke, Schwach, Verena, Passier, Robert, Veenstra, Gert Jan C. · 2025 · Stem Cell Reports
  29. Transcriptome‐wide analysis reveals GYG2 as a mitochondria‐related aging biomarker in human subcutaneous adipose tissue
    Ham, Mira, Cho, Yeonju, Kang, Tae‐Wook, Oh, Taeyun, Kim, Hyoung‐June, Kim, Kyu‐Han · 2024 · Aging Cell
  30. Harnessing the power of single-cell large language models with parameter-efficient fine-tuning using scPEFT
    He, Fei, Fei, Ruixin, Krull, Jordan E., Yu, Yang, Zhang, Xinyu, Wang, Xianyu, Cheng, Hao, Gao, Mingyue, Su, Li, Chen, Yibo et al. · 2025 · Nature Machine Intelligence
  31. A longitudinal analysis of function annotations of the human proteome reveals consistently high biases
    Phan, An, Joshi, Parnal, Kadelka, Claus, Friedberg, Iddo · 2025 · Database
  32. Tetramerisation governs SALL transcription factor function in development and disease
    Giuliani, Sara, Chhatbar, Kashyap, Wear, Martin, Guy, Jacky, Mathieson, Tricia, Burdett, Hayden, George, Lisa, Alston, Grace, Spanos, Christos, McHugh, Toni et al. · 2025 · bioRxiv
  33. Targeting Microglial Transcriptional Reprogramming as a Therapy Strategy for Alzheimer's Disease
    Kim, Byungwook, Wang, Selena S., Kim, Justin R., Kim, Jungsu · 2026 · BioEssays
  34. scTraitReg: a single-cell multi-omic database of trait-relevant transcription factor eRegulons
    Chen, Haoran, Liu, Yin, Rui, Xue, Li, Shengxian, Sun, Lingna, Xiao, Guoli, Tang, Haozhe, Sun, Yanqun, Guan, Xiang, Cao, Chen · 2026 · Nucleic Acids Research
  35. DNA-BFN: Bayesian Flow Networks for Generative Modeling of Regulatory DNA Sequences
    Yu, Han, Du, Qixiu, Wei, Lei, Wang, Xiaowo · 2026 · Bioinformatics