100 years of the Warburg effect: A cancer metabolism endeavor

On the origin of cancer cells

Warburg, O. (1956) · Science · doi:10.1126/science.123.3191.309 · Cited by 13,425

Ferroptosis: mechanisms, biology and role in disease

Jiang, X., Stockwell, B. R., & Conrad, M. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00324-8 · Cited by 7,973

Mutation and cancer: statistical study of retinoblastoma

Knudson, A. G. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.4.820 · Cited by 7,612

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

Engelman, J. A., Luo, J., & Cantley, L. C. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1879 · Cited by 3,330

Aerobic glycolysis: Meeting the metabolic requirements of cell proliferation

Lunt, S. Y., & Vander Heiden, M. G. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154237 · Cited by 3,057

Metabolic reprogramming and cancer progression

Faubert, B., Solmonson, A., & DeBerardinis, R. J. (2020) · Science · doi:10.1126/science.aaw5473 · Cited by 2,740

T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

Kalos, M. D., Levine, B. L., Porter, D. L., Katz, S. I., Grupp, S. A., Bagg, A., & June, C. H. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3002842 · Cited by 2,417

Metabolic Pathways in Immune Cell Activation and Quiescence

Pearce, E. L., & Pearce, E. J. (2013) · Immunity · doi:10.1016/j.immuni.2013.04.005 · Cited by 1,692

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

Kochenderfer, J. N., Wilson, W. H., Janik, J. E., Dudley, M. E., Stetler-Stevenson, M., Feldman, S. A., Maric, I., Raffeld, M., Nathan, D.-A. N., Lanier, B. J., et al. (2010) · Blood · doi:10.1182/blood-2010-04-281931 · Cited by 1,337

Connecting copper and cancer: from transition metal signalling to metalloplasia

Ge, E. J., Bush, A. I., Casini, A., Cobine, P. A., Cross, J. R., DeNicola, G. M., Dou, Q. P., Franz, K. J., Gohil, V. M., Gupta, S. K., et al. (2021) · Nature reviews. Cancer · doi:10.1038/s41568-021-00417-2 · Cited by 1,332

Energy metabolism in health and diseases

Liu, H., Wang, S., Wang, J., Guo, X., Song, Y., Fu, K., Gao, Z., Liu, D., He, W., & Yang, L. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02141-x · Cited by 484

Mitochondrial metabolism and cancer therapeutic innovation

Du, H., Xu, T., Yu, S., Wu, S., & Zhang, J. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02311-x · Cited by 283

Cross-priming in cancer immunology and immunotherapy

Luri‐Rey, C., Teijeira, Á., Wculek, S. K., de Andrea, C. E., Herrero, C., López‐Janeiro, Á., Rodriguez-Ruiz, M. E., Heras‐Murillo, I., Aggelakopoulou, M., Berraondo, P., et al. (2025) · Nature reviews. Cancer · doi:10.1038/s41568-024-00785-5 · Cited by 150

Metabolic interplays between the tumour and the host shape the tumour macroenvironment

Altea‐Manzano, P., Decker-Farrell, A. R., Janowitz, T., & Erez, A. (2025) · Nature reviews. Cancer · doi:10.1038/s41568-024-00786-4 · Cited by 138

Cancer stem cells and niches: challenges in immunotherapy resistance

Pan, Y., Yuan, C., Zeng, C., Sun, C., Xia, L., Wang, G., Chen, X., Zhang, B., Liu, J., & Ding, Z. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02265-2 · Cited by 117

Clinical approaches to overcome PARP inhibitor resistance

Zou, Y., Zhang, H., Chen, P., Tang, J., Yang, S., Nicot, C., Guan, Z., Li, X., & Tang, H. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02355-1 · Cited by 118

The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy

Ma, Q., Zhang, W., Wu, K., & Shi, L. (2025) · Molecular Cancer · doi:10.1186/s12943-024-02218-1 · Cited by 101

mTOR signaling networks: mechanistic insights and translational frontiers in disease therapeutics

Zhang, H., Xiao, X., Pan, Z., & Dokudovskaya, S. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02493-4 · Cited by 94

Tumor-induced metabolic immunosuppression: Mechanisms and therapeutic targets

Ricci, J. (2025) · Cell Reports · doi:10.1016/j.celrep.2024.115206 · Cited by 73

Oncometabolites at the crossroads of genetic, epigenetic and ecological alterations in cancer

Lanzetti, L. (2024) · Cell Death and Differentiation · doi:10.1038/s41418-024-01402-6 · Cited by 57

Acidosis orchestrates adaptations of energy metabolism in tumors

Groessl, S., Kalis, R., Snaebjornsson, M. T., Wambach, L., Haider, J., Andersch, F., Schulze, A., Palm, W., & Zuber, J. A. (2025) · Science · doi:10.1126/science.adp7603 · Cited by 58

Targeting metabolic-epigenetic-immune axis in cancer: molecular mechanisms and therapeutic implications

Wang, X., Luo, X., Xiao, R., Liu, X., Zhou, F., Jiang, D., Bai, J., Cui, M., You, L., & Yupei, Z. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02334-4 · Cited by 59

Decoding the metabolic dialogue in the tumor microenvironment: from immune suppression to precision cancer therapies

Wang, R., Zhuang, J., Zhang, Q., Wu, W., Yu, X., Zhang, H., & Xie, Z. (2025) · Experimental Hematology and Oncology · doi:10.1186/s40164-025-00689-6 · Cited by 52

Lactate and lactylation in cancer: drivers of immune suppression and microenvironmental reprogramming

Ji, X., & Xia, L. (2025) · Experimental Hematology and Oncology · doi:10.1186/s40164-025-00719-3 · Cited by 57

The role and mechanism of fatty acid oxidation in cancer drug resistance

Lei, Y., Cai, S., Zhang, J., Ding, S., Zhang, Z.-H., Zhang, C., Dai, D., & Li, Y. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02554-1 · Cited by 51

IDH Mutations in Glioma: Molecular, Cellular, Diagnostic, and Clinical Implications

Choate, K. A., Pratt, E. P. S., Jennings, M. J., Winn, R. J., & Mann, P. B. (2024) · Biology · doi:10.3390/biology13110885 · Cited by 49

The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome

Luo, L., Zhuang, X., Fu, L., Dong, Z., Yi, S., Wang, K., Jiang, Y., Zhao, J., Yang, X., & Hei, F. (2024) · Clinical and Translational Medicine · doi:10.1002/ctm2.70098 · Cited by 38

Mitochondria-targeting natural product rhein conjugated with dichloroacetate as the dual inhibitor of glycolysis and oxidative phosphorylation to off energize cancer cells and induce ROS storm

Zhang, Z., Tang, S., Qi, M., Zhao, H., Wu, M., & Huang, S. (2025) · Theranostics · doi:10.7150/thno.107812 · Cited by 30

Lactylation in cancer biology: Unlocking new avenues for research and therapy

Hou, X., Hong, Z., Zeng, H., Zhang, C., Zhang, P., Ma, D., & Han, Z. (2025) · 癌症：英文版 · doi:10.1002/cac2.70054 · Cited by 39

Glioma stem cells: drivers of tumor progression and recurrence

He, J., Yan, X., & Hu, S. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04352-z · Cited by 34

Epitranscriptomic control of cancer hallmarks: Functions, mechanisms, and therapeutics of RNA modifications

Deng, X., Wu, D., Zhao, Y., Qing, Y., Wu, H., & Chen, J. (2025) · Cancer Cell · doi:10.1016/j.ccell.2025.12.001 · Cited by 28

Metabolic adaptations in cancer progression

Peng‐Winkler, Y., & Fendt, S. (2025) · Physiological Reviews · doi:10.1152/physrev.00037.2024 · Cited by 25

MPC-mediated lactate production drives histone lactylation in dendritic cells to affect tumor progression and immunotherapy

Zhang, B., Xu, A., Wang, H., Yan, W., Zhang, Q., & Wang, S. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05881-9 · Cited by 27

Advances in the understanding of the role and mechanism of action of PFKFB3‑mediated glycolysis in liver fibrosis (Review)

Liu, Q., Li, J., Li, X., Zhang, L., Yao, S., Wang, Y., Tuo, B., & Jin, H. (2024) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2024.5429 · Cited by 24

SLC7A5/E2F1/PTBP1/PKM2 axis mediates progression and therapy effect of triple-negative breast cancer through the crosstalk of amino acid metabolism and glycolysis pathway.

Jiang, C.-F., Qian, Y.-C., Bai, X., Li, S., Zhang, L., Xie, Y.-X., Lu, Y.-F., Lu, Z.-M., Liu, B., & Jiang, B. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217612 · Cited by 22

Cancer Stem Cells Connecting to Immunotherapy: Key Insights, Challenges, and Potential Treatment Opportunities

Mathan, S. V., & Singh, R. P. (2025) · Cancers · doi:10.3390/cancers17132100 · Cited by 24

Metabolic reprogramming in cancer: signaling pathways and therapeutic targets

Dong, S., & Lei, X. (2026) · Molecular Cancer · doi:10.1186/s12943-026-02582-0 · Cited by 31

Metabolic reprogramming promotes apoptosis resistance in acute lymphoblastic leukemia through CASP3 lactylation

Lin, Z., Long, F., Liu, J., Kang, R., Klionsky, D. J., Kroemer, G., Tang, D., & Yang, M. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02392-w · Cited by 24

Role of gut microbiome in suppression of cancers

Xu, Y., Gao, Z., Liu, J., Yang, Q., & Xu, S. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2495183 · Cited by 21

Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer

Yuan, Q., Sha, Y., Ye, R., Hao, Y., Ni, L., Han, J., & Lin, D. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-07555-3 · Cited by 19

Unraveling the nexus: Genomic instability and metabolism in cancer

Gujar, V. V., Li, H., Paull, T. T., Neumann, C. A., & Weyemi, U. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115540 · Cited by 21

Exploiting metabolic vulnerabilities in cancer: From mechanisms to therapeutic opportunities

Xue, Z.-R., Xin, Y.-Y., & Jin, W. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.218067 · Cited by 21

Targeting mitochondrial structure and dynamics for therapeutic intervention in cancer

Iwata, W., Haggerty, N., Sesaki, H., & Iijima, M. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003453 · Cited by 19

LDHA facilitates immune escape in bladder cancer through H4K5 lactylation-dependent upregulation of PD-L1

Tang, S., Liu, Y., Jin, B., Zhang, T., Wang, X., Zhao, J., Xu, Z., Zhao, W., Bian, H., Li, K., et al. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.117553 · Cited by 18

The impact of glycolysis on ischemic stroke: from molecular mechanisms to clinical applications

Liu, Y., Hu, P., Cheng, H., Xu, F., & Ye, Y. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1514394 · Cited by 17

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Lin, Z., Zheng, Y., Zhong, Y., & Wang, H. (2026) · Advanced Science · doi:10.1002/advs.202510758 · Cited by 13

Lactylation enhances YTHDF3 stability to promote cisplatin resistance via m6A-dependent KDM6B decay in bladder cancer

Yu, K., Sun, J., Zhang, J., Shi, Y., Wang, J., Wu, Y., Lu, D., Niu, X., Li, Y., Huang, S., et al. (2026) · Cancer Letters · doi:10.1016/j.canlet.2026.218282 · Cited by 13

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

Wang, Z., Li, B., Tang, P., Yan, F., Wang, S., Leng, G., Dawa, P., Chen, Y., Guo, Y., Yang, P., et al. (2026) · MedComm – Oncology · doi:10.1002/mog2.70068 · Cited by 14

Endoplasmic reticulum stress on glioblastoma: Tumor growth promotion and immunosuppression

Yang, L., Xue, R., Yang, C., Lv, Y., Li, S., Xiang, W., Guo, X., & Zhou, J. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114806 · Cited by 12

Emerging roles of angiopoietin‑like 4 in human tumors (Review)

Liu, R., Fu, M., Chen, P., Liu, Y., Huang, W., Sun, X., Zhu, P., Wen, Z., & Cheng, Y. (2024) · International Journal of Oncology · doi:10.3892/ijo.2024.5715 · Cited by 12

Metabolite to Modifier: Lactate and Lactylation in the Evolution of Tumors

Zhao, L., Cui, H., Li, Y., Ye, Y., & Shen, Z. (2025) · MedComm · doi:10.1002/mco2.70413 · Cited by 11

Immunosenescence: Molecular Mechanisms, Diseases, and Therapeutic Innovations

Gong, N., Pan, X., Deng, Y., Che, J., Bao, J., Wang, M., Xu, C., Liu, X., & Shi, Y. (2025) · MedComm · doi:10.1002/mco2.70515 · Cited by 14

Nanomedicine-mediated modulation of tumor metabolism for enhanced immunotherapy

Liu, Y., Sun, D., Li, W., Zhang, Z., Li, C., Che, X., & Zhang, S. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114587 · Cited by 10

Intranuclear TCA and mitochondrial overload: The nascent sprout of tumors metabolism

Yuan, W., Lu, G., Zhao, Y., He, X., Liao, S., Wang, Z., Lei, X., Xie, Z., Yang, X., Tang, S., et al. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217527 · Cited by 13

Glutamine metabolism and ammonia death: targeted modulation for enhanced cancer immunotherapy

Du, F., Xiao, L., Guojun, W., Dai, Q., Li, J., Zhao, X., Zhang, Q., Yang, L., Liu, Y., Hu, Y., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1643017 · Cited by 9

Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production

Huggler, K. S., Flickinger, K. M., Forsberg, M. H., Fritz, C. M., Chang, G. R., McGuire, M. F., Capitini, C. M., & Cantor, J. R. (2026) · Nature Metabolism · doi:10.1038/s42255-025-01428-1 · Cited by 10

Comorbidity of hypertension and lung cancer: interplay of genetics and environment

Zeng, J., Shi, D., He, D., Dong, W., Yang, Z., & Chen, Y. (2025) · Discover Oncology · doi:10.1007/s12672-025-03323-3 · Cited by 8

Targeting Metabolic Reprogramming in Tumor: From Mechanisms to Precision Immunotherapies

Zhang, T., Gao, P., & Sun, L. (2025) · MedComm – Oncology · doi:10.1002/mog2.70045 · Cited by 10

Lactate and lactylation in intervertebral disc degeneration

Liu, Y., Yang, J., Wang, Z., Fu, J. H., Liu, H., Lu, Z., Dong, J., Li, Z., Mao, Q., Li, C., et al. (2025) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2025.1685975 · Cited by 9

Regulatory T cells in cancer and inflammation

Yang, H., Zhang, H., Xia, N., & Cheng, X. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-026-02584-w · Cited by 8

Metabolic control of replisome plasticity in genome surveillance

Petersen, M. B., Chhetri, G., & Somyajit, K. (2025) · Trends in Cell Biology · doi:10.1016/j.tcb.2025.01.006 · Cited by 7

Design, Optimization, and Biological Evaluation of a Novel Quinoline-Based POLRMT Inhibitor for Prostate Cancer Therapy

Li, X., Liu, L., Feng, D., Shi, Y., Huang, L., Yu, M., Fu, X., Deng, L., Nie, X., Chen, C., et al. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c00130 · Cited by 8

m6A demethylase FTO drives pancreatic ductal adenocarcinoma tumorigenesis and metastasis through remodeling PFKM mediated glycolysis

Tan, Z., Yang, J., Chen, Y., Zhu, H., Liu, X., He, X., Meng, Q., Xiao, M., Tang, R., Rong, Z., et al. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-08049-2 · Cited by 7

Emerging roles of the metabolic regulator 3-hydroxy-3-methylglutaryl coenzyme-CoA reductase in human cancers: From biology to therapeutics

Li, W.-F., Xu, J., Long, Y., Zhang, H., Rong, X.-J., & Su, Z. (2025) · Genes and Diseases · doi:10.1016/j.gendis.2025.101945 · Cited by 8

Mitochondrial VHL rewires cell metabolism in hypoxia

Li, G., Pan, W., Wu, L., Cai, Z., Chen, H., Wu, X., Yu, T., Liao, K., Zhang, H., 温星桥, et al. (2025) · Cell Metabolism · doi:10.1016/j.cmet.2025.11.013 · Cited by 10

The Spatiotemporal Heterogeneity of Tumor-Associated Stromal Cells: Reprogramming Plasticity to Unlock Precision Cancer Immunotherapy

Lv, Y., Duan, T., Song, J., Liu, S., Zhou, Z., Ba, Y., Weng, S., Zuo, A., Xu, H., Luo, P., et al. (2026) · 癌症：英文版 · doi:10.34133/cancomm.0002 · Cited by 7

Lactylation and acetylation: parallel paths, divergent deeds, and research dilemmas

Jiang, W., Chen, Y., Lin, S., Liu, Y., & Liao, X. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-07877-w · Cited by 8

USP27 promotes glycolysis and hepatocellular carcinoma progression by stabilizing PFKFB3 through deubiquitination

Xie, L., Song, D., Ouyang, Z., Ning, Y., Liu, X., Li, L., Xia, W., & Yang, Y. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111585 · Cited by 7

Lactylation-related molecular subtyping reveals the immune heterogeneity and clinical characteristics in ulcerative colitis

Zhai, J., Fu, R., Luo, S., Liu, X., Xie, Y., Cao, K., Ge, W., & Chen, Y. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.151584 · Cited by 6

An Energy Metabolism Nanoblocker for Cutting Tumor Cell Respiration and Inhibiting Mitochondrial Hijacking from Cytotoxic T Lymphocyte

Leng, X., Yang, Y., Jiang, T., Zheng, J., Zhang, L., Huang, J., Han, X., Fang, M., Li, X., Wang, Z., et al. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202405174 · Cited by 7

Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysis

Lu, Y., Ma, H., Xiong, X., Du, Y., Liu, L., Wang, J., & Zhao, W. (2025) · Scientific Reports · doi:10.1038/s41598-025-94319-0 · Cited by 6

USPs and non-coding RNAs: Unraveling their interplay within tumor microenvironment for targeted cancer therapy

Xu, Y., Wang, J., Deng, X., Gao, H., Xing, F., Ding, H., Qu, L., & Xi, Z. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107853 · Cited by 6

Determining the Biological Features of Aggressive Meningioma Growth with Transcriptomic Profiling

Baluszek, S., Kober, P., Myśliwy, I., Oziȩbło, A., Mandat, T. S., Jezewski, M., & Bujko, M. (2025) · Cancers · doi:10.3390/cancers17203324 · Cited by 8

MUC1 promotes NSCLC progression by regulating ICAM-1-mediated mitochondria transfer from tCAFs to cancer cells

Ji, F., Wang, D., Jin, J., Zhang, J., & Guan, L. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04672-0 · Cited by 6

Microwave-responsive, energy-metabolism-regulating nanosystem for tumor treatment through co-promotion of cuproptosis/ferroptosis

Liu, N., Ren, X., Guo, W., Huang, L., Tan, L., Wu, Q., Fu, C., Zhang, R., Ye, Y., Wu, L., et al. (2025) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2025.139424 · Cited by 6

The Role of Lactate Metabolism in Tumors

Tian, Z., Zhang, K., Sheng, S., Kan, C., Han, F., & Sun, X. (2025) · American Journal of Clinical Oncology · doi:10.1097/coc.0000000000001276 · Cited by 7

Energy metabolism, nutrition and cancer

Camajani, E., Gorini, S., Feraco, A., Armani, A., & Caprio, M. (2026) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2026.01.005 · Cited by 6

Multifunctional copper-based nanoparticles potentiate colorectal cancer immunotherapy via synergistic metabolic remodeling and cGAS-STING pathway activation

Tu, M., Deng, X., Zhou, Z., Li, X., Mao, S., Lai, B., Pang, L., Zhong, Q., Cao, J., Liu, H., et al. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04267-8 · Cited by 8

A machine learning-based glycolysis and fatty acid metabolism-related prognostic signature is constructed and identified ACSL5 as a novel marker inhibiting the proliferation of breast cancer

Liang, M.-Z., Huang, X.-F., Zhu, J., Bao, J., Chen, C., Wang, X., Lou, Y.-W., Pan, Y.-T., & Dai, Y. (2025) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2025.108507 · Cited by 5

Histone lactylation: A new frontier in laryngeal cancer research (Review)

Tong, Q., Huang, C., Tong, Q., & Zhang, Z. (2025) · Oncology Letters · doi:10.3892/ol.2025.15167 · Cited by 5

Aerobic exercise-induced lactate production: a novel opportunity for remodeling the tumor microenvironment

Zhou, X., Jiang, J., Liu, J., Wang, Q., Luo, Y., & Wu, L. (2025) · Frontiers in Genetics · doi:10.3389/fgene.2025.1620723 · Cited by 5

BIX01294 suppresses PDAC growth through inhibition of glutaminase-mediated glutathione dynamics

Im, S. S., Seo, J., You, J., Bang, H. W., Kim, Y., Kweon, J., Kim, Y., Shin, D., & Son, J. (2025) · Molecular Metabolism · doi:10.1016/j.molmet.2025.102113 · Cited by 4

Multimodal therapeutic strategies against gastric cancer: from conventional treatments to tumor microenvironment targeting

Yuan, X., Chen, C., Pang, Y., Wang, X., Yang, T., Long, A., Liang, N., Yang, Y., & Li, C. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1623588 · Cited by 4

Redox‐Active Nanozymes in Metabolic Modulation for Precision Therapeutics

Zhang, W., Wang, M., Ma, P., & Lin, J. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202502110 · Cited by 6

Metabolic reprogramming in diabetes and other endocrine and metabolic disorders: exploring the Warburg effect, ketones, and SGLT2 inhibitors

Carrera‐Bastos, P., Muskiet, M. H. A., Ordóñez, F. M., Pruimboom, L., Lucía, A., Luque, R. M., & Muskiet, F. A. J. (2025) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-025-09996-z · Cited by 5

Discovery of novel chalcone derivatives containing benzimidazole possessing anti-tumor potential in vitro and in vivo

Wang, Q., Qiao, H., Yuan, W., Deng, X., Xie, Z., Lei, X., Yang, X., Tang, G., & Wang, Z. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118912 · Cited by 4

Irisin targets the HK1–glycolysis–NLRP3 pyroptosis axis to prevent chronic kidney disease-associated vascular calcification

Xu, W., Wang, P., Zhu, X., Zhang, Z., Dong, X., An, R., Pang, Q., & Zhang, A. (2025) · Renal Failure · doi:10.1080/0886022x.2025.2610545 · Cited by 4

Downregulation of NFIA facilitates glycolysis, histone lactylation, and activation of the FN1–integrin α5β1 pathway in pancreatic cancer

Zhang, X., Liu, Y., Liu, X., Tan, J., Yuan, L., Wu, W., Li, X., Xi, P., Li, G., & Song, Z. (2026) · APOPTOSIS · doi:10.1007/s10495-025-02218-6 · Cited by 4

A novel microprotein MUCP1 promotes colorectal cancer metabolic reprogramming by regulating mitochondrial succinate transport

Nie, J., Liu, X., Xu, M., Gu, X., Hu, S., Sun, H., Zhou, L., Xu, T., Pan, Y., & Wang, S. (2026) · Neoplasia · doi:10.1016/j.neo.2026.101287 · Cited by 4

The rapamycin sTORy: 50-year journey from Easter Island to the frontiers of biology and medicine

Xiao, X., & Dokudovskaya, S. (2026) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2026.02.004 · Cited by 4

Current research status of the reverse Warburg effect in cancer-associated fibroblasts of solid tumors

Xiao, L., Na, J., Dang, F., Shao, J., Su, J., Zhong, L., & Zhao, Y. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.116586 · Cited by 4

Lactate metabolism-driven lactylation: paradoxical modulation of intestinal inflammation and malignancy

Liu, J. W., Liu, Y., Zhang, H., Li, Z., Fang, X., He, Z., & Bai, Y. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-08041-0 · Cited by 4

Metabolites in the extracellular tumor microenvironment and the shaping of macrophage function

Lamorte, S., Bianca, M., Liu, Z. Q., & McGaha, T. L. (2025) · Molecular Cell · doi:10.1016/j.molcel.2025.09.016 · Cited by 4

Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges

Li, X., Chen, Y., Li, X., Yang, X., Zhou, L., Cheng, Y., Hou, H., Yang, D., Gong, Y., Xiao, H., et al. (2025) · Current Oncology Reports · doi:10.1007/s11912-025-01635-9 · Cited by 6

Heterogeneous protein dynamics links to mitochondrial activity, glucose transporter, and ALDH cancer stem cell properties

Krkoška, M., Tylichová, Z., Zatloukalová, P., Müller, P., Vojtěšek, B., & Coates, P. J. (2025) · BMC Cancer · doi:10.1186/s12885-025-14460-x · Cited by 3

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Unspliced XBP1 enhences metabolic reprogramming in colorectal cancer cells by interfering with the mitochondrial localization of MGME1

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The Impact of IGFBP6 Knockdown on Cholesterol Metabolism in Breast Cancer Cells

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Advances in lipid-based nanosystems for mitochondrial metabolism modulation: strategies, mechanisms, and applications

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Targeting the Warburg Effect for Cancer Therapy: A Long and Winding Road

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Microreviews in Cell and Molecular Biology 2012 Current Findings in Cancer Cell Metabolism

(2016)

Current Findings in Cancer Cell Metabolism

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