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The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System

Zhao, Kexin, Ridgway, Neale D.·2017·Cell Reports
DOI 10.1016/j.celrep.2017.05.028
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  • Other studies provide evidence that cholesterol moves directly from lysosomes to the ER and other membranes.

    “Other studies have provided evidence indicating that cholesterol moves directly from lysosomes to the ER and other membranes (9–12).”

    From Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine (2020) · cites this paper as [10]

    The Discussion identifies a cholesterol transport pathway from late endosomes/lysosomes to the ER at membrane contacts, supporting the ER portion of the claim. It says export to other organelles is poorly understood and does not establish direct transfer to other membranes. (LLM, conf=0.84)

    Experimental — accuracy not yet measured

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Citations

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Research works printed but not linked: 35

  1. Adams, 2004, Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs, J. Biol. Chem., 279, 52772, 10.1074/jbc.M410302200 · DOI
  2. Brown, 2009, Cholesterol feedback: from Schoenheimer’s bottle to Scap’s MELADL, J. Lipid Res., 50, S15, 10.1194/jlr.R800054-JLR200 · DOI · Paper page
  3. Brown, 1978, Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase, J. Biol. Chem., 253, 1121, 10.1016/S0021-9258(17)38120-6 · DOI
  4. Charman, 2014, Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival, J. Biol. Chem., 289, 15705, 10.1074/jbc.M114.571216 · DOI
  5. Chung, 2015, INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts, Science, 349, 428, 10.1126/science.aab1370 · DOI
  6. Cianciola, 2017, Adenovirus modulates toll-like receptor 4 signaling by reprogramming ORP1L-VAP protein contacts for cholesterol transport from endosomes to the endoplasmic reticulum, J. Virol., 91, e01904, 10.1128/JVI.01904-16 · DOI
  7. de Saint-Jean, 2011, Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers, J. Cell Biol., 195, 965, 10.1083/jcb.201104062 · DOI
  8. Dong, 2016, Endosome-ER contacts control actin nucleation and retromer function through VAP-dependent regulation of PI4P, Cell, 166, 408, 10.1016/j.cell.2016.06.037 · DOI · Paper page
  9. Du, 2011, A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking, J. Cell Biol., 192, 121, 10.1083/jcb.201004142 · DOI
  10. Galmes, 2016, ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function, EMBO Rep., 17, 800, 10.15252/embr.201541108 · DOI
  11. Gehrig, 2008, Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha, Mol. Biol. Cell, 19, 237, 10.1091/mbc.e07-02-0179 · DOI
  12. Goldstein, 1983, Receptor-mediated endocytosis of low-density lipoprotein in cultured cells, Methods Enzymol., 98, 241, 10.1016/0076-6879(83)98152-1 · DOI
  13. Goto, 2012, Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis, Mol. Biol. Cell, 23, 3624, 10.1091/mbc.e12-04-0283 · DOI
  14. Infante, 2008, NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes, Proc. Natl. Acad. Sci. USA, 105, 15287, 10.1073/pnas.0807328105 · DOI
  15. Johansson, 2003, The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinct, Mol. Biol. Cell, 14, 903, 10.1091/mbc.e02-08-0459 · DOI
  16. Johansson, 2005, The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments, Mol. Biol. Cell, 16, 5480, 10.1091/mbc.e05-03-0189 · DOI
  17. Kwon, 2009, Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol, Cell, 137, 1213, 10.1016/j.cell.2009.03.049 · DOI · Paper page
  18. Li, 2015, Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells, Proc. Natl. Acad. Sci. USA, 112, 14876, 10.1073/pnas.1520490112 · DOI
  19. Maeda, 2013, Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins, Nature, 501, 257, 10.1038/nature12430 · DOI
  20. Maekawa, 2015, Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol, J. Cell Sci., 128, 1422, 10.1242/jcs.164715 · DOI
  21. Mesmin, 2013, A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP, Cell, 155, 830, 10.1016/j.cell.2013.09.056 · DOI
  22. Ngo, 2009, Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function, Mol. Biol. Cell, 20, 1388, 10.1091/mbc.e08-09-0905 · DOI
  23. Olkkonen, 2013, Oxysterol-binding proteins: sterol and phosphoinositide sensors coordinating transport, signaling and metabolism, Prog. Lipid Res., 52, 529, 10.1016/j.plipres.2013.06.004 · DOI
  24. Ouimet, 2016, miRNA targeting of oxysterol-binding protein-like 6 regulates cholesterol trafficking and efflux, Arterioscler. Thromb. Vasc. Biol., 36, 942, 10.1161/ATVBAHA.116.307282 · DOI
  25. Radhakrishnan, 2007, Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig, Proc. Natl. Acad. Sci. USA, 104, 6511, 10.1073/pnas.0700899104 · DOI · Paper page
  26. Radhakrishnan, 2008, Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance, Cell Metab., 8, 512, 10.1016/j.cmet.2008.10.008 · DOI · Paper page
  27. Rocha, 2009, Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning, J. Cell Biol., 185, 1209, 10.1083/jcb.200811005 · DOI
  28. Russell, 1984, Domain map of the LDL receptor: sequence homology with the epidermal growth factor precursor, Cell, 37, 577, 10.1016/0092-8674(84)90388-X · DOI · Paper page
  29. Sarkar, 2013, Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease, Cell Rep., 5, 1302, 10.1016/j.celrep.2013.10.042 · DOI
  30. Takizawa, 1993, Complete vesiculation of Golgi membranes and inhibition of protein transport by a novel sea sponge metabolite, ilimaquinone, Cell, 73, 1079, 10.1016/0092-8674(93)90638-7 · DOI
  31. van der Kant, 2014, Small regulators, major consequences - Ca2+ and cholesterol at the endosome-ER interface, J. Cell Sci., 127, 929
  32. van der Kant, 2013, Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L, J. Cell Sci., 126, 3462
  33. Vihervaara, 2011, Sterol binding by OSBP-related protein 1L regulates late endosome motility and function, Cell. Mol. Life Sci., 68, 537, 10.1007/s00018-010-0470-z · DOI
  34. Wijdeven, 2016, Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway, Nat. Commun., 7, 11808, 10.1038/ncomms11808 · DOI
  35. Xu, 2008, Regulation of sterol transport between membranes and NPC2, Biochemistry, 47, 11134, 10.1021/bi801328u · DOI

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Metadata

Authors
Zhao, K., & Ridgway, N. D.
Venue
Cell Reports
Publisher
Elsevier BV
Published
2017-05
Volume
19
Issue
9
Pages
1807-1818
ISSN
2211-1247
DOI
10.1016/j.celrep.2017.05.028
Cited by
155
References
4
Language
en
Licence
Funders
  • Canadian Institutes of Health Research (MOP-15284)
  • Bernard and Winnifred Mary Lockwood Endowment

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