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Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P
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The retromer complex interacts with VAP-B, and this interaction occurs in regions where the ER makes contacts with endosomes.
“The retromer complex interacts with VAP-B and such interaction occurs in regions in which the ER makes contacts with endosomes71.”
From Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis (2020) · cites this paper as [71]
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The BioPlex network: a systematic exploration of the human interactome
Huttlin, E. L., Ting, L., Bruckner, R. J., Gebreab, F., Gygi, M. P., Szpyt, J., Tam, S., Zarraga, G., Colby, G., Baltier, K., et al. (2015) · Cell · doi:10.1016/j.cell.2015.06.043 · Cited by 1,425 · cited 1×
“Inspection of a high-throughput VAP interactome (Huttlin et al., 2015) revealed as one of the top hits SNX2, a component of the membrane deformation subcomplex of the retromer (Bonifacino and Rojas, 2006).”
Lipid landscapes and pipelines in membrane homeostasis
Holthuis, J. C. M., & Menon, A. K. (2014) · Nature · doi:10.1038/nature13474 · Cited by 901
Retromer: A Master Conductor of Endosome Sorting
Burd, C., & Cullen, P. J. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016774 · Cited by 435
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Metadata
- Authors
- Dong, R., Saheki, Y., Swarup, S., Lucast, L., Harper, J. W., & De Camilli, P.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2016-07
- Volume
- 166
- Issue
- 2
- Pages
- 408-423
- ISSN
- 0092-8674
- PMC
- PMC4963242
- Cited by
- 398
- References
- 3
- Language
- en
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