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let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7
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“The highly conserved let-7b, one of the most abundant miRNAs in the human brain (20, 21), is released from dying CNS cells and triggers neuroinflammation and neurodegeneration through direct activation of TLR7 (5, 6).”
From UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b (2021) · cites this paper as [6]
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“In addition, TLR7 was recently discovered to detect extracellular microRNA (miRNA), such as let-7 (5, 6).”
From UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b (2021) · cites this paper as [6]
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Cites
Kettenmann, H., Hanisch, U.-K., Noda, M., & Verkhratsky, A. (2011) · Physiological Reviews · doi:10.1152/physrev.00011.2010 · Cited by 3,547
Self-citationInnate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
Diebold, S. S., Kaisho, T., Hemmi, H., Akira, S., & Reis e Sousa, C. (2004) · Science · doi:10.1126/science.1093616 · Cited by 3,444
Cell Signalling by MicroRNA165/6 Directs Gene Dose-Dependent Root Cell Fate
Carlsbecker, A., Lee, J.-Y., Roberts, C. J., Dettmer, J., Lehesranta, S., Zhou, J., Lindgren, O., Moreno-Risueno, M. A., Vatén, A., Thitamadee, S., et al. (2010) · Nature · doi:10.1038/nature08977 · Cited by 861
Saederup, N., Cardona, A. E., Croft, K., Mizutani, M., Cotleur, A. C., Tsou, C.-L., Ransohoff, R. M., & Charo, I. F. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013693 · Cited by 599
Wlodarczyk, A., Løbner, M., Cédile, O., & Owens, T. (2014) · Journal of Neuroinflammation · doi:10.1186/1742-2094-11-57 · Cited by 149
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Sorted by citations
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O’Brien, K., Breyne, K., Ughetto, S., Laurent, L. C., & Breakefield, X. O. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0251-y · Cited by 1,811
Klammer, M. G., Dzaye, O., Wallach, T., Krüger, C., Gaessler, D., Buonfiglioli, A., Derkow, K., Kettenmann, H., Brinkmann, M. M., & Lehnardt, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.715774 · Cited by 6
Self-citation
Metadata
- Authors
- Buonfiglioli, A., Efe, I. E., Guneykaya, D., Ivanov, A., Huang, Y., Orlowski, E., Krüger, C., Deisz, R. A., Markovic, D., Flüh, C., Newman, A. G., Schneider, U. C., Beule, D., Wolf, S. A., Dzaye, O., Gutmann, D. H., Semtner, M., Kettenmann, H., & Lehnardt, S.
- Venue
- Cell Reports
- Publisher
- Elsevier BV
- Published
- 2019-12
- Volume
- 29
- Issue
- 11
- Pages
- 3460-3471.e7
- ISSN
- 2211-1247
- Cited by
- 86
- References
- 5
- Language
- en
- Licence
- Funders
- Alexander von Humboldt-Stiftung
- Deutsche Forschungsgemeinschaft (LE 2420/2-1, SFB-TRR167/B3)
- Berlin Institute of Health
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