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Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

Lie, Pearl P.Y., Yang, Dun-Sheng, Stavrides, Philip, Goulbourne, Chris N., Zheng, Ping, Mohan, Panaiyur S., Cataldo, Anne M., Nixon, Ralph A.·2021·Cell Reports

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  1. Abeliovich, 2016, Defects in trafficking bridge Parkinson’s disease pathology and genetics, Nature, 539, 207, 10.1038/nature20414 · DOI · Paper page
  2. Andrä, 1996, Expression of APP in transgenic mice: a comparison of neuron-specific promoters, Neurobiol. Aging, 17, 183, 10.1016/0197-4580(95)02066-7 · DOI
  3. Authier, 1996, Endosomal proteolysis of internalized proteins, FEBS Lett., 389, 55, 10.1016/0014-5793(96)00368-7 · DOI
  4. Bagh, 2017, Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model, Nat. Commun., 8, 14612, 10.1038/ncomms14612 · DOI
  5. Banting, 1997, TGN38 and its orthologues: roles in post-TGN vesicle formation and maintenance of TGN morphology, Biochim. Biophys. Acta, 1355, 209, 10.1016/S0167-4889(96)00146-2 · DOI
  6. Benes, 2008, Cathepsin D--many functions of one aspartic protease, Crit. Rev. Oncol. Hematol., 68, 12, 10.1016/j.critrevonc.2008.02.008 · DOI · Paper page
  7. Boland, 2008, Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer’s disease, J. Neurosci., 28, 6926, 10.1523/JNEUROSCI.0800-08.2008 · DOI · Paper page
  8. Bomati, 2014, Spectral and structural comparison between bright and dim green fluorescent proteins in Amphioxus, Sci. Rep., 4, 5469, 10.1038/srep05469 · DOI
  9. Broadwell, 1984, The neuronal endoplasmic reticulum: its cytochemistry and contribution to the endomembrane system. II. Axons and terminals, J. Comp. Neurol., 230, 231, 10.1002/cne.902300208 · DOI
  10. Carlsson, 1992, The lysosomal membrane glycoprotein lamp-1 is transported to lysosomes by two alternative pathways, Arch. Biochem. Biophys., 296, 630, 10.1016/0003-9861(92)90619-8 · DOI
  11. Cataldo, 1990, Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer’s disease: evidence for a neuronal origin, Brain Res., 513, 181, 10.1016/0006-8993(90)90456-L · DOI
  12. Cataldo, 1991, Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease, Proc. Natl. Acad. Sci. USA, 88, 10998, 10.1073/pnas.88.24.10998 · DOI
  13. Cataldo, 2004, Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology, J. Neuropathol. Exp. Neurol., 63, 821, 10.1093/jnen/63.8.821 · DOI
  14. Chen, 2017, Segregation in the Golgi complex precedes export of endolysosomal proteins in distinct transport carriers, J. Cell Biol., 216, 4141, 10.1083/jcb.201707172 · DOI · Paper page
  15. Cheng, 2015, Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes, J. Cell Biol., 209, 377, 10.1083/jcb.201412046 · DOI
  16. Cheng, 2018, Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons, J. Cell Biol., 217, 3127, 10.1083/jcb.201711083 · DOI · Paper page
  17. Colacurcio, 2016, Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease, Ageing Res. Rev., 32, 75, 10.1016/j.arr.2016.05.004 · DOI · Paper page
  18. Damme, 2015, Autophagy in neuronal cells: general principles and physiological and pathological functions, Acta Neuropathol., 129, 337, 10.1007/s00401-014-1361-4 · DOI
  19. De Luca, 2015, RILP regulates vacuolar ATPase through interaction with the V1G1 subunit, J. Cell Sci., 128, 2565, 10.1242/jcs.175323 · DOI
  20. Deinhardt, 2006, Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway, Neuron, 52, 293, 10.1016/j.neuron.2006.08.018 · DOI
  21. Demaurex, 1998, Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface, J. Biol. Chem., 273, 2044, 10.1074/jbc.273.4.2044 · DOI
  22. Farfel-Becker, 2019, Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity, Cell Rep., 28, 51, 10.1016/j.celrep.2019.06.013 · DOI · Paper page
  23. Farías, 2017, BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon, Proc. Natl. Acad. Sci. USA, 114, E2955, 10.1073/pnas.1616363114 · DOI · Paper page
  24. Ghosh, 2016, VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8, Nat. Commun., 7, 10489, 10.1038/ncomms10489 · DOI
  25. Gowrishankar, 2015, Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques, Proc. Natl. Acad. Sci. USA, 112, E3699, 10.1073/pnas.1510329112 · DOI · Paper page
  26. Gowrishankar, 2017, Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology, J. Cell Biol., 216, 3291, 10.1083/jcb.201612148 · DOI · Paper page
  27. Han, 2020, Mitophagy regulates integrity of mitochondria at synapses and is critical for synaptic maintenance, EMBO Rep., 21, e49801, 10.15252/embr.201949801 · DOI
  28. Hara, 2006, Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice, Nature, 441, 885, 10.1038/nature04724 · DOI · Paper page
  29. Holcomb, 1998, Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes, Nat. Med., 4, 97, 10.1038/nm0198-097 · DOI · Paper page
  30. Janvier, 2005, Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins, Mol. Biol. Cell, 16, 4231, 10.1091/mbc.e05-03-0213 · DOI
  31. Jin, 2018, Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals, Curr. Biol., 28, 1027, 10.1016/j.cub.2018.02.032 · DOI
  32. Komatsu, 2006, Loss of autophagy in the central nervous system causes neurodegeneration in mice, Nature, 441, 880, 10.1038/nature04723 · DOI · Paper page
  33. Kornbrot, 2018, Quality science from quality measurement: The role of measurement type with respect to replication and effect size magnitude in psychological research, PLoS ONE, 13, e0192808, 10.1371/journal.pone.0192808 · DOI
  34. Kuijpers, 2020, The axonal endolysosomal and autophagic systems, J. Neurochem.
  35. Lalli, 2002, Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR, J. Cell Biol., 156, 233, 10.1083/jcb.200106142 · DOI
  36. Lee, 2010, Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations, Cell, 141, 1146, 10.1016/j.cell.2010.05.008 · DOI · Paper page
  37. Lee, 2011, Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer’s-like axonal dystrophy, J. Neurosci., 31, 7817, 10.1523/JNEUROSCI.6412-10.2011 · DOI
  38. Lee, 2019, Transgenic expression of a ratiometric autophagy probe specifically in neurons enables the interrogation of brain autophagy in vivo, Autophagy, 15, 543, 10.1080/15548627.2018.1528812 · DOI
  39. Li, 2014, The signaling lipid PI(3,5)P2 stabilizes V1-V(o) sector interactions and activates the V-ATPase, Mol. Biol. Cell, 25, 1251, 10.1091/mbc.e13-10-0563 · DOI
  40. Li, 2019, Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles, Cell Rep., 28, 1015, 10.1016/j.celrep.2019.06.006 · DOI
  41. Lie, 2019, Lysosome trafficking and signaling in health and neurodegenerative diseases, Neurobiol. Dis., 122, 94, 10.1016/j.nbd.2018.05.015 · DOI
  42. Liu, 2017, WDR91 is a Rab7 effector required for neuronal development, J. Cell Biol., 216, 3307, 10.1083/jcb.201705151 · DOI
  43. Luini, 2008, Morphogenesis of post-Golgi transport carriers, Histochem. Cell Biol., 129, 153, 10.1007/s00418-007-0365-8 · DOI
  44. Meyer, 2000, mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors, EMBO J., 19, 2193, 10.1093/emboj/19.10.2193 · DOI · Paper page
  45. Miedel, 2006, Posttranslational cleavage and adaptor protein complex-dependent trafficking of mucolipin-1, J. Biol. Chem., 281, 12751, 10.1074/jbc.M511104200 · DOI
  46. Millet, 2007, Microfluidic devices for culturing primary mammalian neurons at low densities, Lab Chip, 7, 987, 10.1039/b705266a · DOI
  47. Nakata, 1998, Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons, J. Cell Biol., 140, 659, 10.1083/jcb.140.3.659 · DOI
  48. Nixon, 2013, The role of autophagy in neurodegenerative disease, Nat. Med., 19, 983, 10.1038/nm.3232 · DOI · Paper page
  49. Nixon, 1984, Degradation of neurofilament proteins by purified human brain cathepsin D, J. Neurochem., 43, 507, 10.1111/j.1471-4159.1984.tb00928.x · DOI
  50. Nixon, 2005, Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study, J. Neuropathol. Exp. Neurol., 64, 113, 10.1093/jnen/64.2.113 · DOI · Paper page
  51. Overly, 1996, Dynamic organization of endocytic pathways in axons of cultured sympathetic neurons, J. Neurosci., 16, 6056, 10.1523/JNEUROSCI.16-19-06056.1996 · DOI
  52. Overly, 1995, Quantitative measurement of intraorganelle pH in the endosomal-lysosomal pathway in neurons by using ratiometric imaging with pyranine, Proc. Natl. Acad. Sci. USA, 92, 3156, 10.1073/pnas.92.8.3156 · DOI
  53. Parton, 1992, Axonal and dendritic endocytic pathways in cultured neurons, J. Cell Biol., 119, 123, 10.1083/jcb.119.1.123 · DOI
  54. Pols, 2013, hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins, Nat. Commun., 4, 1361, 10.1038/ncomms2360 · DOI
  55. Pu, 2015, BORC, a multisubunit complex that regulates lysosome positioning, Dev. Cell, 33, 176, 10.1016/j.devcel.2015.02.011 · DOI · Paper page
  56. Pu, 2017, A Ragulator-BORC interaction controls lysosome positioning in response to amino acid availability, J. Cell Biol., 216, 4183, 10.1083/jcb.201703094 · DOI
  57. Saftig, 2009, Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function, Nat. Rev. Mol. Cell Biol., 10, 623, 10.1038/nrm2745 · DOI · Paper page
  58. Sankaranarayanan, 2000, The use of pHluorins for optical measurements of presynaptic activity, Biophys. J., 79, 2199, 10.1016/S0006-3495(00)76468-X · DOI
  59. Shim, 2006, CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis, J. Cell Biol., 172, 1045, 10.1083/jcb.200509041 · DOI
  60. Snouwaert, 2018, A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice, Cell Rep., 24, 1254, 10.1016/j.celrep.2018.06.118 · DOI · Paper page
  61. Tammineni, 2017, Impaired retrograde transport of axonal autophagosomes contributes to autophagic stress in Alzheimer’s disease neurons, eLife, 6, e21776, 10.7554/eLife.21776 · DOI
  62. Tanida, 2014, A super-ecliptic, pHluorin-mKate2, tandem fluorescent protein-tagged human LC3 for the monitoring of mammalian autophagy, PLoS ONE, 9, e110600, 10.1371/journal.pone.0110600 · DOI
  63. Tsukita, 1980, The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles, J. Cell Biol., 84, 513, 10.1083/jcb.84.3.513 · DOI
  64. Urwin, 2010, Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations, Hum. Mol. Genet., 19, 2228, 10.1093/hmg/ddq100 · DOI
  65. Vukoja, 2018, Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles, Neuron, 99, 1216, 10.1016/j.neuron.2018.08.004 · DOI
  66. Xu, 2015, Lysosomal physiology, Annu. Rev. Physiol., 77, 57, 10.1146/annurev-physiol-021014-071649 · DOI
  67. Yang, 2008, Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer’s disease, Am. J. Pathol., 173, 665, 10.2353/ajpath.2008.071176 · DOI
  68. Yang, 2009, Monitoring autophagy in Alzheimer’s disease and related neurodegenerative diseases, Methods Enzymol., 453, 111, 10.1016/S0076-6879(08)04006-8 · DOI
  69. Yap, 2018, Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes, J. Cell Biol., 217, 3141, 10.1083/jcb.201711039 · DOI
  70. Yasuda, 1999, Characterization of new fluorogenic substrates for the rapid and sensitive assay of cathepsin E and cathepsin D, J. Biochem., 125, 1137, 10.1093/oxfordjournals.jbchem.a022396 · DOI
  71. Zheng, 2019, Somatic autophagy of axonal mitochondria in ischemic neurons, J. Cell Biol., 218, 1891, 10.1083/jcb.201804101 · DOI

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Metadata

Authors
Lie, P. P. Y., Yang, D.-S., Stavrides, P., Goulbourne, C. N., Zheng, P., Mohan, P. S., Cataldo, A. M., & Nixon, R. A.
Venue
Cell Reports
Publisher
Elsevier BV
Published
2021-04
Volume
35
Issue
4
Pages
109034
ISSN
2211-1247
Cited by
97
References
14
Language
en
Funders
National Institutes of Health (P01AG017617, R01AG062376)

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