Arthritis flares mediated by tissue-resident memory T cells in the joint

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2009) · Nature Protocols · doi:10.1038/nprot.2008.211 · Cited by 35,890 · see citing works

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkn923 · Cited by 14,108 · see citing works

A global double-fluorescent Cre reporter mouse

Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L., & Luo, L. (2007) · genesis · doi:10.1002/dvg.20335 · Cited by 3,491 · see citing works

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

Zhang, F., Wei, K., Slowikowski, K., Fonseka, C. Y., Rao, D. A., Kelly, S., Goodman, S. M., Tabechian, D. A., Hughes, L. B., Salomon-Escoto, K., et al. (2019) · Nature Immunology · doi:10.1038/s41590-019-0378-1 · Cited by 1,380 · see citing works

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

Mackay, L. K., Rahimpour, A., Ma, J. Z., Collins, N., Stock, A. T., Hafon, M.-L., Vega-Ramos, J., Lauzurica, P., Mueller, S. N., Stefanovic, T., et al. (2013) · Nature Immunology · doi:10.1038/ni.2744 · Cited by 1,331 · see citing works

The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study

Cross, M., Smith, E. U. R., Hoy, D. G., Carmona, L., Wolfe, F., Vos, T., Williams, B., Gabriel, S. E., Lassere, M. N., Johns, N. E., et al. (2014) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2013-204627 · Cited by 1,157 · see citing works

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

Rao, D. A., Gurish, M. F., Marshall, J. L., Slowikowski, K., Fonseka, C. Y., Liu, Y., Donlin, L. T., Henderson, L. A., Wei, K., Mizoguchi, F., et al. (2017) · Nature · doi:10.1038/nature20810 · Cited by 1,125 · see citing works

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

Kumar, B. V., Ma, W., Miron, M., Granot, T., Guyer, R. S., Carpenter, D. J., Senda, T., Sun, X., Ho, S.-H., Lerner, H., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.08.078 · Cited by 1,068 · see citing works

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

Mackay, L. K., Minnich, M., Kragten, N. A. M., Liao, Y., Nota, B., Seillet, C., Zaid, A., Man, K., Preston, S., Freestone, D., et al. (2016) · Science · doi:10.1126/science.aad2035 · Cited by 1,010 · see citing works

Distinct fibroblast subsets drive inflammation and damage in arthritis

Croft, A. P., Campos, J., Jansen, K., Turner, J. D., Marshall, J., Attar, M., Savary, L., Wehmeyer, C., Naylor, A. J., Kemble, S., et al. (2019) · Nature · doi:10.1038/s41586-019-1263-7 · Cited by 976 · see citing works

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

Raychaudhuri, S., Sandor, C., Stahl, E. A., Freudenberg, J., Lee, H. S., Jia, X., Alfredsson, L. S., Padyukov, L., Klareskog, L., Worthington, J., et al. (2012) · Nature Genetics · doi:10.1038/ng.1076 · Cited by 947 · see citing works

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

Jiang, X., Clark, R. A., Liu, L., Wagers, A. J., Fuhlbrigge, R. C., & Kupper, T. S. (2012) · Nature · doi:10.1038/nature10851 · Cited by 883 · see citing works

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

Schenkel, J. M., Fraser, K. A., Beura, L. K., Pauken, K. E., Vezys, V., & Masopust, D. (2014) · Science · doi:10.1126/science.1254536 · Cited by 731 · see citing works

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

Pan, Y., Tian, T., Park, C. O., Lofftus, S. Y., Mei, S., Liu, X., Luo, C., O’Malley, J. T., Gehad, A. E., Teague, J. E., et al. (2017) · Nature · doi:10.1038/nature21379 · Cited by 718 · see citing works

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

Cheuk, S., Schlums, H., Gallais Sérézal, I., Martini, E., Chiang, S. C., Marquardt, N., Gibbs, A., Detlofsson, E., Introini, A., Forkel, M., et al. (2017) · Immunity · doi:10.1016/j.immuni.2017.01.009 · Cited by 678 · see citing works

Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours

Milner, J. J., Toma, C., Yu, B., Zhang, K., Omilusik, K., Phan, A. T., Wang, D., Getzler, A. J., Nguyen, T., Crotty, S., et al. (2017) · Nature · doi:10.1038/nature24993 · Cited by 677 · see citing works

Location, location, location: Tissue resident memory T cells in mice and humans

Szabo, P. A., Miron, M., & Farber, D. L. (2019) · Science Immunology · doi:10.1126/sciimmunol.aas9673 · Cited by 651 · see citing works

Sensing and alarm function of resident memory CD8+ T cells

Schenkel, J., Fraser, K. A., Vezys, V., & Masopust, D. (2013) · Nature Immunology · doi:10.1038/ni.2568 · Cited by 648 · see citing works

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

Watanabe, R., Gehad, A., Yang, C., Scott, L. L., Teague, J. E., Schlapbach, C., Elco, C. P., Huang, V., Matos, T. R., Kupper, T. S., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.3010302 · Cited by 569 · see citing works

Spontaneous Development of Psoriasis in a New Animal Model Shows an Essential Role for Resident T Cells and Tumor Necrosis Factor-α

Boyman, O., Hefti, H. P., Conrad, C., Nickoloff, B. J., Suter, M., & Nestle, F. O. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031482 · Cited by 521 · see citing works

The emerging role of resident memory T cells in protective immunity and inflammatory disease

Park, C. O., & Kupper, T. S. (2015) · Nature Medicine · doi:10.1038/nm.3883 · Cited by 514 · see citing works

Cutting Edge: CD69 Interference with Sphingosine-1-Phosphate Receptor Function Regulates Peripheral T Cell Retention

Mackay, L. K., Braun, A., Macleod, B. L., Collins, N., Tebartz, C., Bedoui, S., Carbone, F. R., & Gebhardt, T. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402256 · Cited by 503 · see citing works

Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells

Sénéschal, J., Clark, R. A., Gehad, A. E., Baecher‐Allan, C., & Kupper, T. S. (2012) · Immunity · doi:10.1016/j.immuni.2012.03.018 · Cited by 454 · see citing works

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

Barber, E. K., Dasgupta, J. D., Schlossman, S. F., Trevillyan, J. M., & Rudd, C. E. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.9.3277 · Cited by 452 · see citing works

Resident memory T cells in human health and disease

Clark, R. A. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.3010641 · Cited by 445 · see citing works

Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

Lewis, M., Barnes, M. R., Blighe, K., Goldmann, K., Rana, S., Hackney, J. A., Ramamoorthi, N., John, C. R., Watson, D., Kummerfeld, S., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.07.091 · Cited by 425 · see citing works

Cadherin-11 in Synovial Lining Formation and Pathology in Arthritis

Lee, D. M., Kiener, H. P., Agarwal, S. K., Noss, E. H., Watts, G. F. M., Chisaka, O., Takeichi, M., & Brenner, M. B. (2007) · Science · doi:10.1126/science.1137306 · Cited by 415 · see citing works

Skin Effector Memory T Cells Do Not Recirculate and Provide Immune Protection in Alemtuzumab-Treated CTCL Patients

Clark, R. A., Watanabe, R., Teague, J. E., Schlapbach, C., Tawa, M. C., Adams, N., Dorosario, A. A., Chaney, K. S., Cutler, C. S., LeBoeuf, N. R., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003008 · Cited by 367 · see citing works

Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice

Misharin, A. V., Cuda, C. M., Saber, R., Turner, J. D., Gierut, A. K., Haines, G. K., Berdnikovs, S., Filer, A. D., Clark, A. R., Buckley, C. D., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.09.032 · Cited by 326 · see citing works

Resident Memory T Cells (TRM) Are Abundant in Human Lung: Diversity, Function, and Antigen Specificity

Purwar, R., Campbell, J. J., Murphy, G. F., Richards, W. G., Clark, R. A., & Kupper, T. S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016245 · Cited by 286 · see citing works

Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation

Woetzel, D., Huber, R., Kupfer, P., Pohlers, D., Pfaff, M., Driesch, D., Häupl, T., Koczan, D., Stiehl, P., Guthke, R., et al. (2014) · Arthritis Research & Therapy · doi:10.1186/ar4526 · Cited by 278 · see citing works

A High-Dimensional Atlas of Human T Cell Diversity Reveals Tissue-Specific Trafficking and Cytokine Signatures

Wong, M. T., Ong, D. E. H., Lim, F. S. H., Teng, K. W. W., McGovern, N. N., Narayanan, S., Ho, W. Q., Cerny, D., Tan, H. K. K., Anicete, R., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.07.007 · Cited by 244 · see citing works

Tissue‐resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance

Gebhardt, T., Palendira, U., Tscharke, D. C., & Bedoui, S. (2018) · Immunological Reviews · doi:10.1111/imr.12650 · Cited by 199 · see citing works

Transcriptional Regulation of Tissue-Resident Lymphocytes

Mackay, L. K., & Kallies, A. (2016) · Trends in Immunology · doi:10.1016/j.it.2016.11.004 · Cited by 196 · see citing works

Adeno-associated virus effectively mediates conditional gene modification in the brain

Kaspar, B. K., Vissel, B., Bengoechea, T. G., Crone, S. A., Randolph‐Moore, L., Müller, R., Brandon, E. P., Schaffer, D. V., Verma, I. M., Lee, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.042678699 · Cited by 195 · see citing works

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes

Ai, R., Laragione, T., Hammaker, D. R., Boyle, D. L., Wildberg, A., Maeshima, K., Palescandolo, E., Krishna, V., Pocalyko, D. J., Whitaker, J. W., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04310-9 · Cited by 192 · see citing works

CD8 T Cells Are Required for the Formation of Ectopic Germinal Centers in Rheumatoid Synovitis

Kang, Y. M., Zhang, X., Wagner, U. G., Yang, H., Beckenbaugh, R. D., Kurtin, P. J., Goronzy, J. J., & Weyand, C. M. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011565 · Cited by 186 · see citing works

Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity

Han, B., Diogo, D., Eyre, S., Källberg, H., Zhernakova, A., Bowes, J., Padyukov, L., Okada, Y., González-Gay, M. Á., Rantapää‐Dahlqvist, S., et al. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2014.02.013 · Cited by 180 · see citing works

E-cadherin promotes accumulation of a unique memory CD8 T-cell population in murine salivary glands

Hofmann, M., & Pircher, H. (2011) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1107200108 · Cited by 173 · see citing works

Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis

Ungethuem, U., Haeupl, T., Witt, H., Koczan, D., Krenn, V., Huber, H., Helversen, T. V., Drungowski, M., Seyfert, C., Zacher, J., et al. (2010) · Physiological Genomics · doi:10.1152/physiolgenomics.00004.2010 · Cited by 150 · see citing works

Review: Genetics and the Classification of Arthritis in Adults and Children

Nigrovic, P. A., Raychaudhuri, S., & Thompson, S. D. (2017) · Arthritis & Rheumatology · doi:10.1002/art.40350 · Cited by 150 · see citing works

Supplementation of diet with krill oil protects against experimental rheumatoid arthritis

Ierna, M. X., Kerr, A., Scales, H. E., Berge, K., & Griinari, M. (2010) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-11-136 · Cited by 147 · see citing works

Biological classification of childhood arthritis: roadmap to a molecular nomenclature

Nigrovic, P. A., Colbert, R. A., Holers, V. M., Özen, S., Ruperto, N., Thompson, S. D., Wedderburn, L. R., Yeung, R. S. M., & Martini, A. (2021) · Nature Reviews Rheumatology · doi:10.1038/s41584-021-00590-6 · Cited by 138 · see citing works

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation

Petrelli, A., Mijnheer, G., van Konijnenburg, D. P. H., van der Wal, M. M., Giovannone, B., Mocholi, E., Vazirpanah, N., Broen, J. C., Hijnen, D., Oldenburg, B., et al. (2018) · Journal of Clinical Investigation · doi:10.1172/jci96107 · Cited by 126 · see citing works

Direct Evidence for Interferon-γ Production by Effector-Memory-Type Intraepidermal T Cells Residing at an Effector Site of Immunopathology in Fixed Drug Eruption

Mizukawa, Y., Yamazaki, Y., Teraki, Y., Hayakawa, J., Hayakawa, K., Nuriya, H., Kohara, M., & Shiohara, T. (2002) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64410-0 · Cited by 125 · see citing works

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells

Akitsu, A., Ishigame, H., Kakuta, S., Chung, S.-H., Ikeda, S., Shimizu, K., Kubo, S., Liu, Y., Umemura, M., Matsuzaki, G., et al. (2015) · Nature Communications · doi:10.1038/ncomms8464 · Cited by 121 · see citing works

Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses

Low, J. S., Farsakoglu, Y., Vesely, M. C. A., Sefik, E., Kelly, J. B., Harman, C. C. D., Jackson, R. P., Shyer, J. A., Jiang, X., Cauley, L. S., et al. (2020) · The Journal of Experimental Medicine · doi:10.1084/jem.20192291 · Cited by 117 · see citing works

Local immunity by tissue-resident CD8+ memory T cells

Gebhardt, T., & Mackay, L. K. (2012) · Front. Immun. · doi:10.3389/fimmu.2012.00340 · Cited by 103 · see citing works

Cutting Edge: Regulator of G Protein Signaling-1 Selectively Regulates Gut T Cell Trafficking and Colitic Potential

Gibbons, D. L., Abeler‐Dörner, L., Raine, T., Hwang, I., Jandke, A., Wencker, M., Deban, L., Rudd, C. E., Irving, P. M., Kehrl, J. H., et al. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1100833 · Cited by 102 · see citing works

The role of osteoprotegerin and receptor activator of nuclear factor ?B ligand in the pathogenesis and treatment of rheumatoid arthritis

Hofbauer, L. C., & Heufelder, A. E. (2001) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200102)44:2 · Cited by 100 · see citing works

Sustained rheumatoid arthritis remission is uncommon in clinical practice

Prince, F. H. M., Bykerk, V. P., Shadick, N. A., Lü, B., Cui, J., Frits, M. L., Iannaccone, C. K., Weinblatt, M. E., & Solomon, D. H. (2012) · Arthritis Research & Therapy · doi:10.1186/ar3785 · Cited by 99 · see citing works

Bone Marrow T Cells and the Integrated Functions of Recirculating and Tissue-Resident Memory T Cells

Rosa, F. D., & Gebhardt, T. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00051 · Cited by 84 · see citing works

Integrin and transcriptomic profiles identify a distinctive synovial CD8+ T cell subpopulation in spondyloarthritis

Qaiyum, Z., Gracey, E., Yao, Y., & Inman, R. D. (2019) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2019-215349 · Cited by 80 · see citing works

Induction of an acute erosive monarticular arthritis in mice by interleukin‐1 and methylated bovine serum albumin

Staite, N. D., Richard, K. A., Aspar, D. G., Franz, K. A., Galinet, L. A., & Dunn, C. J. (1990) · Arthritis & Rheumatism · doi:10.1002/art.1780330215 · Cited by 72 · see citing works

Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells

Pharoah, D. S., Varsani, H., Tatham, R. W., Newton, K. R., de Jager, W., Prakken, B. J., Klein, N. J., & Wedderburn, L. R. (2006) · Arthritis Research & Therapy · doi:10.1186/ar1913 · Cited by 67 · see citing works

Antibody-dependent and -independent mechanisms of inflammatory arthritis

Chang, M. H., & Nigrovic, P. A. (2019) · JCI Insight · doi:10.1172/jci.insight.125278 · Cited by 55 · see citing works

Murine Antigen-Induced Arthritis

van den Berg, W. B., Joosten, L. A. B., & van Lent, P. L. E. M. (2007) · Methods in molecular medicine · doi:10.1007/978-1-59745-402-5_18 · Cited by 53 · see citing works

Tissue Exit: a Novel Control Point in the Accumulation of Antigen-Specific CD8 T Cells in the Influenza A Virus-Infected Lung

Jennrich, S., Lee, M. H., Lynn, R. C., Dewberry, K., & Debes, G. F. (2012) · Journal of Virology · doi:10.1128/jvi.07025-11 · Cited by 41 · see citing works

Assessment of hazard risk associated with the intravenous use of viral vectors in rodents.

Reuter, J. D., Fang, X., Ly, C. S., Suter, K. K., & Gibbs, D. (2012) · Europe PMC (PubMed Central) · Cited by 22 · see citing works

Stability of normal joint findings in persistent classic rheumatoid arthritis

Roberts, W. N., Daltroy, L. H., & Anderson, R. J. (1988) · Arthritis & Rheumatism · doi:10.1002/art.1780310215 · Cited by 22 · see citing works

AB0218 CORRELATION BETWEEN IMMUNOLOGICAL PARAMETERS AND PULMONARY FUNCTION PARAMETERS IN THE PATIENTS WITH SSC AND ILD OVER 5 YEARFOLLOW UP STUDY

Ovsyannikova, O. B., Ananyeva, L. P., Koneva, O., GARZANOVA, L., Starovoytova, M., & Desinova, O. (2019) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2019-eular.7932 · Cited by 2 · see citing works

The pathogenesis of rheumatoid arthritis

Alivernini, S., Firestein, G. S., & McInnes, I. B. (2022) · Immunity · doi:10.1016/j.immuni.2022.11.009 · Cited by 739 · see citing works

Mechanisms of joint destruction in rheumatoid arthritis — immune cell–fibroblast–bone interactions

Komatsu, N., & Takayanagi, H. (2022) · Nature Reviews Rheumatology · doi:10.1038/s41584-022-00793-5 · Cited by 554 · see citing works

Energy metabolism in health and diseases

Liu, H., Wang, S., Wang, J., Guo, X., Song, Y., Fu, K., Gao, Z., Liu, D., He, W., & Yang, L. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02141-x · Cited by 438 · see citing works

Classification of human chronic inflammatory skin disease based on single-cell immune profiling

Liu, Y., Wang, H., Taylor, M. A., Cook, C. P., Martínez‐Berdeja, A., North, J. P., Harirchian, P., Hailer, A., Zhao, Z., Ghadially, R., et al. (2022) · Science Immunology · doi:10.1126/sciimmunol.abl9165 · Cited by 176 · see citing works

Clinical and translational attributes of immune-related adverse events

Suijkerbuijk, K. P. M., van Eijs, M. J. M., van Wijk, F., & Eggermont, A. M. M. (2024) · Nature Cancer · doi:10.1038/s43018-024-00730-3 · Cited by 128 · see citing works

Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis

Moon, J., Younis, S., Ramadoss, N. S., Iyer, R., Sheth, K., Sharpe, O., Rao, N. L., Bécart, S., Carman, J., James, E. A., et al. (2023) · Nature Communications · doi:10.1038/s41467-022-35264-8 · Cited by 110 · see citing works

Contextual AI models for single-cell protein biology

Li, M. M., Huang, Y., Sumathipala, M. G., Liang, M. Q., Valdeolivas, A., Ananthakrishnan, A. N., Liao, K. P., Marbach, D., & Žitnik, M. (2024) · Nature Methods · doi:10.1038/s41592-024-02341-3 · Cited by 77 · see citing works

Sequential immunotherapy: towards cures for autoimmunity

Ramírez‐Valle, F., Maranville, J., Roy, S., & Plenge, R. M. (2024) · Nature Reviews Drug Discovery · doi:10.1038/s41573-024-00959-8 · Cited by 80 · see citing works

Tissue-resident immune cells: from defining characteristics to roles in diseases

Li, J., Chu, X., Li, C., & He, J. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02050-5 · Cited by 80 · see citing works

Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium

Dunlap, G. S., Wagner, A., Meednu, N., Wang, R. H., Zhang, F., Ekabe, C. J., Jonsson, A. H., Wei, K. S., Sakaue, S., Nathan, A., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49186-0 · Cited by 72 · see citing works

Immune checkpoint receptors in autoimmunity

Burke, K. P., Patterson, D. G., Liang, D., & Sharpe, A. H. (2023) · Current Opinion in Immunology · doi:10.1016/j.coi.2023.102283 · Cited by 70 · see citing works

Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis

MacDonald, L., Elmesmari, A., Somma, D., Frew, J., Mario, C. D., Madhu, R., Paoletti, A., Simakou, T., Hardy, O. M., Tolusso, B., et al. (2024) · Immunity · doi:10.1016/j.immuni.2024.11.004 · Cited by 65 · see citing works

Psoriatic and rheumatoid arthritis joints differ in the composition of CD8+ tissue-resident memory T cell subsets

Povoleri, G. A. M., Durham, L. E., Gray, E. H., Lalnunhlimi, S., Kannambath, S., Pitcher, M. J., Dhami, P., Leeuw, T., Ryan, S. E., Steel, K. J. A., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112514 · Cited by 58 · see citing works

TCR-sequencing in cancer and autoimmunity: barcodes and beyond

Pauken, K. E., Lagattuta, K. A., Lu, B. Y., Lucca, L. E., DAUD, A. I., Hafler, D. A., Kluger, H. M., Raychaudhuri, S., & Sharpe, A. H. (2022) · Trends in Immunology · doi:10.1016/j.it.2022.01.002 · Cited by 59 · see citing works

Regulation of activated T cell survival in rheumatic autoimmune diseases

Rosetti, F., Madera-Salcedo, I. K., Rodríguez‐Rodríguez, N., & Crispín, J. C. (2022) · Nature Reviews Rheumatology · doi:10.1038/s41584-021-00741-9 · Cited by 53 · see citing works

Autoimmune Myocarditis, Old Dogs and New Tricks.

Won, T., Song, E. J., Kalinoski, H. M., Moslehi, J. J., & Čiháková, D. (2024) · Circulation Research · doi:10.1161/circresaha.124.323816 · Cited by 51 · see citing works

Metabolic dysregulation of lymphocytes in autoimmune diseases

Wang, S., Yang, N., & Zhang, H. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.01.005 · Cited by 48 · see citing works

Mortality and immune-related adverse events after immune checkpoint inhibitor initiation for cancer among patients with pre-existing rheumatoid arthritis: a retrospective, comparative, cohort study

McCarter, K. R., Wolfgang, T., Arabelovic, S., Wang, X., Yoshida, K., Banasiak, E., Qian, G., Kowalski, E. N., Vanni, K. M. M., LeBoeuf, N. R., et al. (2023) · The Lancet Rheumatology · doi:10.1016/s2665-9913(23)00064-4 · Cited by 44 · see citing works

Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission

Baker, K. F., McDonald, D., Hulme, G., Hussain, R., Coxhead, J. M., Swan, D. J., Schulz, A. R., Mei, H. E., MacDonald, L., Pratt, A. G., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45213-2 · Cited by 48 · see citing works

Tissue-resident memory T cells in epicardial adipose tissue comprise transcriptionally distinct subsets that are modulated in atrial fibrillation

Vyas, V. S., Sandhar, B. S., Keane, J. M., Wood, E. G., Blythe, H. C., Jones, A. R. C., Shahaj, E., Fanti, S., Williams, J. L., Metic, N., et al. (2024) · Nature Cardiovascular Research · doi:10.1038/s44161-024-00532-x · Cited by 38 · see citing works

Distinct immune-effector and metabolic profile of CD8+ T cells in patients with autoimmune polyarthritis induced by therapy with immune checkpoint inhibitors

Benesova, K., Kraus, F. V., Carvalho, R. A., Lorenz, H., Hoerth, C. H., Günther, J., Klika, K. D., Graf, J., Diekmann, L., Schank, T. E., et al. (2022) · Annals of the Rheumatic Diseases · doi:10.1136/ard-2022-222451 · Cited by 35 · see citing works

Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis

Chang, M. H., Fuhlbrigge, R. C., & Nigrovic, P. A. (2024) · Nature Reviews Rheumatology · doi:10.1038/s41584-024-01107-7 · Cited by 35 · see citing works

Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis

Stavre, Z., Kim, J., Yang, Y.-S., Nündel, K., Chaugule, S. R., Sato, T., Park, K. H., Gao, G., Gravallese, E. M., & Shim, J. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2218019120 · Cited by 29 · see citing works

From PsO to PsA: the role of TRM and Tregs in psoriatic disease, a systematic review of the literature

Lobão, B., Lourenço, D., Giga, A., & Mendes‐Bastos, P. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1346757 · Cited by 30 · see citing works

Memory Cells in Infection and Autoimmunity: Mechanisms, Functions, and Therapeutic Implications

Giri, S., & Batra, L. (2025) · Vaccines · doi:10.3390/vaccines13020205 · Cited by 27 · see citing works

Remodeling of T-cell mitochondrial metabolism to treat autoimmune diseases

Lin, L., Ren, R., Xiong, Q., Zheng, C., Yang, B., & Wang, H. (2024) · Autoimmunity Reviews · doi:10.1016/j.autrev.2024.103583 · Cited by 27 · see citing works

Resident cutaneous memory T cells: a clinical review of their role in chronic inflammatory dermatoses and potential as therapeutic targets

Pham, J. P., Wark, K. J. L., Woods, J. A., & Frew, J. W. (2023) · British Journal of Dermatology · doi:10.1093/bjd/ljad303 · Cited by 26 · see citing works

Inflammatory tissue priming: novel insights and therapeutic opportunities for inflammatory rheumatic diseases

Hoffmann, M. H., Kirchner, H., Krönke, G., Riemekasten, G., & Bonelli, M. M. (2024) · Annals of the Rheumatic Diseases · doi:10.1136/ard-2023-224092 · Cited by 24 · see citing works

Irradiated tumor cell-released microparticles enhance the therapeutic efficacy of PD-1 inhibitors by promoting M1-TAMs polarization in NSCLC brain metastases

Li, J., Bai, M., Jia, W., Zhai, X., Wang, M., Yu, J., & Zhu, H. Q. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.217133 · Cited by 22 · see citing works

CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjögren’s Syndrome

Hinrichs, A. C., Blokland, S. L. M., Kruize, A. A., Lafeber, F. P. J. G., Leavis, H. L., & van Roon, J. A. G. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.887972 · Cited by 21 · see citing works

Tissue-resident memory T cells: The key frontier in local synovitis memory of rheumatoid arthritis

Gao, A., Zhao, W., Wu, R., Su, R. J., Jin, R., Luo, J., Gao, C., Li, X., & Wang, C. (2022) · Journal of Autoimmunity · doi:10.1016/j.jaut.2022.102950 · Cited by 22 · see citing works

T Cell Dysregulation in Rheumatoid Arthritis: from Genetic Susceptibility to Established Disease

Chin, A., Small, A., Wong, S. W., & Wechalekar, M. D. (2025) · Current Rheumatology Reports · doi:10.1007/s11926-025-01180-1 · Cited by 19 · see citing works

Immunocyte lipid metabolic reprogramming: a novel pathway for targeted intervention in autoimmune diseases

Cui, Y.-Y., Feng, Z.-D., Zhao, Q.-H., Dai, H., Zheng, Y., Rui, H.-L., & Liu, B.-L. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1713148 · Cited by 17 · see citing works

Exosomal Osteoclast-Derived miRNA in Rheumatoid Arthritis: From Their Pathogenesis in Bone Erosion to New Therapeutic Approaches

Pascual-García, S., Martínez-Peinado, P., Pujalte-Satorre, C., Navarro‐Sempere, A., Esteve-Girbés, J., López-Jaén, A. B., Javaloyes-Antón, J., Cobo, R., Navarro-Blasco, F. J., & Sempere-Ortells, J. M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031506 · Cited by 19 · see citing works

Novel approach to alleviate lupus nephritis: targeting the NLRP3 inflammasome in CD8+CD69+CD103+ TRM cells

Lai, Y., Zhuang, L., Zhu, J., Wang, S., Guo, C., Chen, B., Li, J., Shi, J., Li, M., Yang, N., et al. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05951-9 · Cited by 18 · see citing works

Characteristics of the (Auto)Reactive T Cells in Rheumatoid Arthritis According to the Immune Epitope Database

Carlé, C., Degboé, Y., Ruyssen‐Witrand, A., Arleevskaya, M. I., Clavel, C., & Renaudineau, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054296 · Cited by 18 · see citing works

Joint‐Specific Memory and Sustained Risk for New Joint Accumulation in Autoimmune Arthritis

Chang, M. H., Bocharnikov, A. V., Case, S., Todd, M., Laird, J., Baumgartner, M. A., & Nigrovic, P. A. (2022) · Arthritis & Rheumatology · doi:10.1002/art.42240 · Cited by 18 · see citing works

Insights Into the Concept of Rheumatoid Arthritis Flare

Cassione, E. B., Grignaschi, S., Xoxi, B., Luvaro, T., Greco, M. I., Mazzucchelli, I., Bugatti, S., Montecucco, C., & Manzo, A. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.852220 · Cited by 17 · see citing works

Immunomodulatory Nanoparticles for Modulating Arthritis Flares

Johnson, W. T., McBride, D. A., Kerr, M., Nguyen, A., Zoccheddu, M., Bollmann, M., Wei, X., Jones, R. M., Wang, W., Svensson, M. N. D., et al. (2023) · ACS Nano · doi:10.1021/acsnano.3c05298 · Cited by 17 · see citing works

Resident Memory T Cells in the Atherosclerotic Lesion Associate With Reduced Macrophage Content and Increased Lesion Stability

de Jong, M. J. M., Depuydt, M. A. C., Schaftenaar, F. H., Liu, K., Maters, D., Wezel, A., Smeets, H. J., Kuiper, J., Bot, I., van Gisbergen, K. P. J. M., et al. (2024) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.123.320511 · Cited by 17 · see citing works

Identification of biomarkers associated with CD8+ T cells in rheumatoid arthritis and their pan-cancer analysis

Zhao, Z.-Y., Ren, J., Xie, S.-P., Zou, L., Zhao, Q.-Y., Zeng, S., & Zha, D.-S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1044909 · Cited by 8 · see citing works

Effectiveness of Yishen Tongbi decoction versus methotrexate in patients with active rheumatoid arthritis: A double-blind, randomized, controlled, non-inferiority trial

Xu, J., Zhang, L., Xu, Y., Yu, J., Zhao, L., Deng, H., Li, M., Zhang, M., Lei, X., Hu, C., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154704 · Cited by 15 · see citing works

Substantive Similarities Between Synovial Fluid and Synovial Tissue T cells in Inflammatory Arthritis Via Single‐Cell RNA and T Cell Receptor Sequencing

Durham, L. E., Humby, F., Ng, N., Ryan, S. E., Nuamah, R. A., Fung, K., Kallayil, A. M., Dhami, P., Kirkham, B. W., & Taams, L. S. (2024) · Arthritis & Rheumatology · doi:10.1002/art.42949 · Cited by 14 · see citing works

Vaccines prevent reinduction of rheumatoid arthritis symptoms in collagen-induced arthritis mouse model

Thumsi, A., Swaminathan, S. J., Mangal, J. L., Suresh, A. P., & Acharya, A. P. (2023) · Drug Delivery and Translational Research · doi:10.1007/s13346-023-01333-8 · Cited by 12 · see citing works

T cell trafficking in human chronic inflammatory diseases

Giovenzana, A., Codazzi, V., Pandolfo, M., & Petrelli, A. (2024) · iScience · doi:10.1016/j.isci.2024.110528 · Cited by 11 · see citing works

Lipid droplet-induced T cell death sustains autoimmune tissue inflammation

Kumar, J., Takashima, Y., Morales, J., Wong, B. H. S., Werner, L., Goronzy, I. N., Rubino, S., Trousdale, R. T., Berry, G. J., Goronzy, J. J., et al. (2026) · Cell Metabolism · doi:10.1016/j.cmet.2026.01.014 · Cited by 10 · see citing works

Patterns and determinants of response to novel therapies in juvenile and adult-onset polyarthritis

Triaille, C., Quartier, P., Somer, L. D., Durez, P., Lauwerys, B. R., Verschueren, P., Taylor, P. C., & Wouters, C. H. (2023) · Lara D. Veeken · doi:10.1093/rheumatology/kead490 · Cited by 10 · see citing works

Rheumatoid arthritis synovial fibroblasts modulate T cell activation

Romoff, M. R., Periyakoil, P. K., DiCarlo, E. F., Ramirez, D. C., Goodman, S. M., Leslie, C. S., Rudensky, A. Y., Donlin, L. T., & Smith, M. H. (2025) · JCI Insight · doi:10.1172/jci.insight.193054 · Cited by 10 · see citing works

T H 17 cells converted into exT H 17 cells sustain rheumatoid-like IL-17–independent inflammatory arthritis

Zoccheddu, M., Suga, K., Seng, A., Svensson, M. N. D., Dutta, P., Panahandeh, S., Makinde, H. M., Ro, M., Wang, Y., Kim, H., et al. (2025) · Science Immunology · doi:10.1126/sciimmunol.adm7800 · Cited by 10 · see citing works

Patterns of clinical joint inflammation in juvenile idiopathic arthritis

Heckert, S. L., Muller, P. C. E. H., van den Berg, J. M., Schonenberg‐Meinema, D., van Suijlekom‐Smit, L. W. A., van Rossum, M. A. J., Koopman-Keemink, Y., Cate, R. T., Brinkman, D. M. C., Huizinga, T. W. J., et al. (2023) · RMD Open · doi:10.1136/rmdopen-2022-002941 · Cited by 10 · see citing works

Distinct mast cell subpopulations within and around lymphatic vessels regulate lymph flow and progression of inflammatory-erosive arthritis in TNF-transgenic mice

Peng, Y. H., Kenney, H. M., Bentley, K. L. D. M., Xing, L., Ritchlin, C. T., & Schwarz, E. M. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1275871 · Cited by 12 · see citing works

Tissue‐resident memory T cells in immunotherapy and immune‐related adverse events by immune checkpoint inhibitor

Xiong, H., & Shen, Z. (2024) · International Journal of Cancer · doi:10.1002/ijc.34940 · Cited by 9 · see citing works

Metabolic regulation of tissue-resident immune cells: Molecular mechanisms and therapeutic implications

Chen, Z.-X., Xiao, F., Zhu, X., Zhou, W., Rui, K., Lu, L., & Tian, J. (2025) · Metabolism · doi:10.1016/j.metabol.2025.156349 · Cited by 9 · see citing works

Tissue-Resident Memory T Cells in Rheumatoid Immune Diseases: Pathogenic Mechanisms and Therapeutic Strategies

Tian, Y., Zhang, J., Wu, L., Zhang, C., Zheng, F., Yang, Y., Lu, G., & Xie, D. (2025) · Biomedicines · doi:10.3390/biomedicines13122945 · Cited by 9 · see citing works

The clinical and experimental treatment of Juvenile Idiopathic Arthritis

Nijhuis, L., Swart, J. F., Prakken, B. J., van Loosdregt, J., & Vastert, S. J. (2023) · Clinical & Experimental Immunology · doi:10.1093/cei/uxad045 · Cited by 8 · see citing works

Identification of CD8+ T cell-related biomarkers and immune infiltration characteristic of rheumatoid arthritis

Wang, Q., Li, Q., Wang, R., Li, Y., Wang, J., Guo, Z., Li, F., Chen, B., Xiang, H., Wang, T., et al. (2024) · Aging · doi:10.18632/aging.205435 · Cited by 8 · see citing works

Progression of pre-rheumatoid arthritis to clinical disease of joints: Potential role of mesenchymal stem cells

Sardana, Y., Bhatti, G. K., Singh, C., Sharma, P. K., Reddy, P. H., & Bhatti, J. S. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.121641 · Cited by 7 · see citing works

Higher densities of T-lymphocytes in the subsynovial connective tissue of people with carpal tunnel syndrome

Sandy-Hindmarch, O. P., Álvarez, M. M., Wiberg, A., Furniss, D., & Schmid, A. B. (2024) · PLoS ONE · doi:10.1371/journal.pone.0300046 · Cited by 6 · see citing works

Mitophagy drives maldifferentiation of tissue-resident memory T cells in patients with rheumatoid arthritis

Liu, T., Wang, M., Li, L., Wu, T., Ji, H., Zheng, M., Tang, L., Gan, W.-J., Wen, Z., & Yuan, F. (2024) · Scandinavian Journal of Rheumatology · doi:10.1080/03009742.2024.2420432 · Cited by 6 · see citing works

Tissue resident memory T cells populate the human uveal tract

Foers, A. D., Reekie, I. R., Wickramasinghe, L. C., Ward, A., Buckley, T. M. W., Attar, M., Aguilar-Munoa, S., Pilapil, Q., Elsayed, M. E. A. A., Pledger, S., et al. (2026) · Scientific Reports · doi:10.1038/s41598-025-33444-2 · Cited by 6 · see citing works

Deciphering the molecular landscape of rheumatoid arthritis offers new insights into the stratified treatment for the condition

Chang, M., Feng, Q.-F., Hao, J.-W., Zhang, Y., Zhao, R., Li, N., Zhao, Y., Han, Z., He, P. F., & Wang, C. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1391848 · Cited by 6 · see citing works

Unveiling the crucial role of CD8+ T cell and endothelial cell interaction in rheumatoid arthritis through the integrated analysis of spatial transcriptomics and bulk/single-cell RNA-seq

Lai, Y., Zhong, Z., Li, R., Liang, T., He, X., Liu, Y., Yu, H., Zhang, C., Xiao, Y., Liu, L., et al. (2025) · Journal of Translational Autoimmunity · doi:10.1016/j.jtauto.2025.100285 · Cited by 5 · see citing works

Adipose tissue harbors pathogenic T cells in obesity that exacerbate inflammatory arthritis

Faust, H. J., Chang, M. H., Jonsson, A. H., Theisen, E., LaMarche, N. M., Trim, W. V., Lynch, L., Nigrovic, P. A., & Brenner, M. B. (2025) · The Journal of Experimental Medicine · doi:10.1084/jem.20240677 · Cited by 5 · see citing works

Tissue-Resident Memory T Cells in Gastrointestinal Cancers: Prognostic Significance and Therapeutic Implications

Sato, H., Meng, S., Hara, T., Tsuji, Y., Arao, Y., Sasaki, K., Kobayashi, S., di Luccio, E., Hirotsu, T., Satoh, T., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12061342 · Cited by 5 · see citing works

Erasing the memory of arthritis in joints

Onuora, S. (2021) · Nature Reviews Rheumatology · doi:10.1038/s41584-021-00730-y · Cited by 5 · see citing works

Restoring Immunological Tolerance via Dendritic Cells in Rheumatoid Arthritis

Costello, H., Woodcock, A., & Canavan, M. (2026) · European Journal of Immunology · doi:10.1002/eji.70136 · Cited by 4 · see citing works

Emerging biochemical, microbial and immunological evidence in the search for why HLA-B∗27 confers risk for spondyloarthritis

Brown, E., Nguyen, P. N. U., & Xavier, R. J. (2024) · Cell chemical biology · doi:10.1016/j.chembiol.2024.07.012 · Cited by 4 · see citing works

Polymorphic Analysis of Genes PADI4 (rs2240340, rs1748033) and HLA-DRB1 (rs2395175) in Arthritis Patients in Pakistani Population

Bashir, K., Chaudhary, A., Aslam, M., Fatima, I., & Sarwar, R. (2023) · Biochemical Genetics · doi:10.1007/s10528-023-10513-7 · Cited by 4 · see citing works

Inflammatory arthritis immune related adverse events represent a unique autoimmune disease entity primarily driven by T cells, but likely not autoantibodiesPreprint

Zhu, X., Yu, Y., Li, Y., Wang, P., Li, Y., McCabe, C. E., Chen, S., Langenfeld, H. E., Hanson, A. C., Sharp, B. E., et al. (2025) · medRxiv · doi:10.1101/2025.06.06.25328991 · Cited by 4 · see citing works

Is psoriatic arthritis a dissemination of cutaneous psoriatic TRM cells? Role of tissue-resident memory T cells (TRM) in psoriatic disease

Raychaudhuri, S. P., & Raychaudhuri, S. K. (2025) · Current Opinion in Immunology · doi:10.1016/j.coi.2025.102702 · Cited by 3 · see citing works

Inflammatory arthritis irAE may represent a unique autoimmune disease primarily driven by T cells but likely not autoantibodies

Zhu, X., Yu, Y., Chen, S., Langenfeld, H. E., Li, Y., Wang, P., Li, Y., McCabe, C. E., Hanson, A. C., Sharp, B., et al. (2026) · Science Advances · doi:10.1126/sciadv.aea4262 · Cited by 3 · see citing works

Characterization of pathogenic synovial IL-17A-producing CD8+ T cell subsets in collagen-induced arthritis

Zhang, S., Zhou, Y., Yang, P., Jia, S., Peng, C. M., Hu, H., & Liu, W. (2022) · Cellular Immunology · doi:10.1016/j.cellimm.2022.104655 · Cited by 3 · see citing works

Emerging synovial cell states in rheumatoid arthritis as potential therapeutic targets

Mantel, I., Fein, M. R., & Donlin, L. T. (2023) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000940 · Cited by 3 · see citing works

Effect of Integrin Blockade on Experimental Spondyloarthritis

Yau, E., Lim, M., Qaiyum, Z., Foroozan-Boroojeni, S., Tang, M., Pacheco, A., Tavasolian, F., & Inman, R. D. (2024) · Biomolecules · doi:10.3390/biom14111386 · Cited by 2 · see citing works

The joint accumulation model of arthritis

Nigrovic, P. A. (2025) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2025.152685 · Cited by 2 · see citing works

Comprehensive and advanced T cell cluster analysis for discriminating seropositive and seronegative rheumatoid arthritis

Maeda, S., Hashimoto, H., Maeda, T., Tamechika, S., Naniwa, T., & Niimi, A. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1491041 · Cited by 2 · see citing works

Immunomodulatory Nanoparticles Enable Combination Therapies To Enhance Disease Prevention and Flare Control in Rheumatoid Arthritis

Johnson, W. T., Wilkinson, E. L., Iyer, N., Dolmat, M., Bollmann, M., Dada, N., Wei, X., Yang, S., Zhang, T. X., Yoo, G., et al. (2025) · ACS Central Science · doi:10.1021/acscentsci.5c00723 · Cited by 2 · see citing works

Navigating the Hurdles of Intra-Articular AAV Gene Therapy

Li, W., Thornton, O. R., Feng, S. L., & Li, C. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262010123 · Cited by 2 · see citing works

Tissue‐Resident Memory T Cells: Pioneering New Avenues in Cancer Immunotherapy

Xiao, Y., Yang, Q., & Sun, Z. (2025) · Cancer Medicine · doi:10.1002/cam4.71429 · Cited by 3 · see citing works

Understanding the Inflammatory Aspect of Osteoarthritis: Lessons from Immune Checkpoint Inhibitors

Portnoy, D. M., Paiola, M., Tymm, C. C., WINCHESTER, R. J., Mor, A., & Gartshteyn, Y. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15020658 · Cited by 3 · see citing works

Synovial lymphatic system structure and function in rheumatoid arthritis: lymphatic phases, telocytes, and therapeutic modulation through Eexercise

Peng, Y. H., Belcher, D. J., Kobryn, A., Cole, C. L., & Schwarz, E. (2026) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000001151 · Cited by 2 · see citing works

Fat bursts T cells to drive joint inflammation

Li, W., & Tsokos, G. C. (2026) · Cell Metabolism · doi:10.1016/j.cmet.2026.02.007 · Cited by 2 · see citing works

Immunopathological mechanisms and targeted intervention strategies for chronic chikungunya arthritis: from viral persistence to autoimmunity

Zeng, L., Lai, W. P., Li, Y. P., Yang, M., Liang, J., Li, M., Mo, Z., Li, Y. P., Liu, Y., Li, X., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1775493 · Cited by 2 · see citing works

Tissue‐Resident Memory T Cells in the Heart: An Emerging Role in Chronic Inflammation

Manandhar, P., Yan, A., & Moslehi, J. J. (2026) · Immunological Reviews · doi:10.1111/imr.70134 · Cited by 2 · see citing works

All fibroblasts are equal, but some are more equal than others

Bolton, C., & Croft, A. P. (2024) · Nature Reviews Rheumatology · doi:10.1038/s41584-024-01097-6 · Cited by 2 · see citing works

Please don’t go: retinoic acid ‘retains’ tissue-specific memory

Stanczak, M. A., & Pearce, E. L. (2024) · Trends in Immunology · doi:10.1016/j.it.2024.11.005 · Cited by 2 · see citing works

Risk of knee osteoarthritis in patients with multiple atopic conditions: a nationwide study

Park, D., Choi, Y., Han, K., Koh, H.-S., & Koh, H. S. (2025) · Scientific Reports · doi:10.1038/s41598-025-92247-7 · Cited by 2 · see citing works

Computational estimation of clonal diversity in autoimmunity

Tuong, Z. K., van der Merwe, R., Cañete, P. F., & Roco, J. A. (2024) · Immunology and Cell Biology · doi:10.1111/imcb.12801 · Cited by 2 · see citing works

A stitch of CD9 saves nine: CD9+ tissue-resident memory T cells in Sjogren's syndrome and autoimmunity

Li, D., & Zhang, S. (2023) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiad096 · Cited by 2 · see citing works

A Potential CD8 + T‐Cell‐Related Biomarker IFIT3 for Rheumatoid Arthritis

Tian, K., Guo, J., Yan, Q., & Wang, N. (2025) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.70385 · Cited by 1 · see citing works

The likelihood of joint inflammation recurrence in previously affected joints during psoriatic arthritis disease course

Berman, M., Elkayam, O., & Capelusnik, D. (2025) · Annals of the Rheumatic Diseases · doi:10.1016/j.ard.2025.08.020 · Cited by 1 · see citing works

Using mass cytometry to probe the STAT signaling landscape in circulating immune cells in Rheumatoid Arthritis uncovers signaling dysregulation and correlation with disease activity

Macaubas, C., Bayram, B., Hussein, N. A., Jager, A., Davis, K. L., Graf, J. D., Nakamura, M. C., Zisman, D., & Mellins, E. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1622537 · Cited by 1 · see citing works

Exploring perinatal mesenchymal stromal cells as a potential therapeutic strategy for rheumatoid arthritis

Alivernini, S., Masserdotti, A., Magatti, M., Cargnoni, A., Papait, A., Silini, A. R., Romoli, J., Ficai, S., Mario, C. D., Gremese, E., et al. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e41438 · Cited by 1 · see citing works

Reply to Tilotta and Bongiorno: Considering the role of resident cutaneous memory T‐cell suppression in providing durable atopic dermatitis remission

Pham, J. P., & Frew, J. W. (2023) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.19179 · Cited by 1 · see citing works

The role of CCR9-expressing T cell subsets in the immunopathology of primary Sjögren's syndrome

Hinrichs, A. C. (2023) · doi:10.33540/756

Screening for central targets and the commonalities between rheumatoid arthritis and idiopathic pulmonary fibrosis based on bioinformaticsPreprint

wu, Y., Lei, K.-T., Wang, Z., Lu, Y., Zhu, W. T., & Wang, Y. (2024) · Research Square · doi:10.21203/rs.3.rs-3804234/v1

ABCD of IA: A multi-scale agent-based model of T cell activation in inflammatory arthritis

McBride, D. A., Wang, J. S., Johnson, W. T., Bottini, N., & Shah, N. J. (2024) · Biomaterials Science · doi:10.1039/d3bm01674a

Characterization of Immune Checkpoint Inhibitor-Associated Arthritis: Insights from the Two Global Pharmacovigilance Databases of FAERS and VigiBasePreprint

Lin, A., Jiang, A., Tang, B., Liu, Y., Wang, L., Liu, Z., Cheng, Q., Zhang, J., & Luo, P. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4854762

Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid ArthritisPreprint

MacDonald, L., Elmesmari, A., Somma, D., Frew, J., Mario, C. D., Madhu, R., Paoletti, A., Simakou, T., Hardy, O. M., Tolusso, B., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.17.600758

Recirculating and Resident Memory CD8+ T Cells

Gebhardt, T., Newland, L. G. M., & Bedoui, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-12-824465-4.00285-4

Erasing the memory of arthritis in joints

Onuora, S. (2021) · Nature Reviews Rheumatology · doi:10.1038/s41584-021-00730-y · Cited by 5 · see citing works

Tissue-resident memory T cells: The key frontier in local synovitis memory of rheumatoid arthritis

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