The role of cholesterol in membrane fusion

Functional rafts in cell membranes

Simons, K., & Ikonen, E. (1997) · Nature · doi:10.1038/42408 · Cited by 9,757 · cited 3× · see citing works

Membrane lipids: where they are and how they behave

van Meer, G., Voelker, D. R., & Feigenson, G. W. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2330 · Cited by 7,157 · see citing works

Lipid rafts as a membrane-organizing principle

Lingwood, D., & Simons, K. (2010) · Science · doi:10.1126/science.1174621 · Cited by 4,417 · see citing works

Evidence for the Formation of Symmetric and Asymmetric DLPC-DAPC Lipid Bilayer Domains

Ritter, M., Schmidt, S., Jakab, M., Paulmichl, M., & Henderson, R. M. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350122 · Cited by 3,923 · see citing works

Functions of lipid rafts in biological membranes.

Brown, D. A., & London, E. (1998) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.14.1.111 · Cited by 3,027 · see citing works

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

Srimaroeng, C., Cecile, J. P., Walden, R., & Pritchard, J. B. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350077 · Cited by 2,989 · see citing works

Membrane Fusion

Wilschut, J. (1990) · Cited by 2,407 · see citing works

Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension

Baumgart, T., Hess, S. T., & Webb, W. W. (2003) · Nature · doi:10.1038/nature02013 · Cited by 1,601 · see citing works

Viral membrane fusion

Harrison, S. C. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1456 · Cited by 1,191 · see citing works

Entropy-driven tension and bending elasticity in condensed-fluid membranes

Evans, E., & Rawicz, W. (1990) · Physical Review Letters · doi:10.1103/physrevlett.64.2094 · Cited by 1,129 · see citing works

Lipid rafts: at a crossroad between cell biology and physics

Jacobson, K., Mouritsen, O. G., & Anderson, R. G. W. (2007) · Nature Cell Biology · doi:10.1038/ncb0107-7 · Cited by 1,105 · see citing works

Mechanics of membrane fusion

Chernomordik, L. V., & Kozlov, M. M. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1455 · Cited by 1,037 · see citing works

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

Hanson, M. A., Cherezov, V., Griffith, M. T., Roth, C., Jaakola, V., Chien, E. Y. T., Velasquez, J., Kühn, P., & Stevens, R. C. (2008) · Structure · doi:10.1016/j.str.2008.05.001 · Cited by 935 · see citing works

Protein-lipid interplay in fusion and fission of biological membranes.

Chernomordik, L., & Kozlov, M. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161504 · Cited by 793 · see citing works

Seeing spots: Complex phase behavior in simple membranes

Veatch, S. L., & Keller, S. L. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2005.06.010 · Cited by 767 · see citing works

SNAREs are concentrated in cholesterol‐dependent clusters that define docking and fusion sites for exocytosis

Lang, T., Bruns, D., Wenzel, D., Riedel, D., Holroyd, P., Thiele, C., & Jahn, R. (2001) · The EMBO Journal · doi:10.1093/emboj/20.9.2202 · Cited by 686 · see citing works

HIV-1 assembly, release and maturation

Freed, E. O. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3490 · Cited by 654 · see citing works

Interaction of influenza virus haemagglutinin with sphingolipid–cholesterol membrane domains via its transmembrane domain

Scheiffele, P., Roth, M. G., & Simons, K. (1997) · The EMBO Journal · doi:10.1093/emboj/16.18.5501 · Cited by 638 · see citing works

How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains

Fantini, J., & Barrantes, F. J. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00031 · Cited by 532 · see citing works

Influenza Virus M2 Protein Mediates ESCRT-Independent Membrane Scission

Rossman, J. S., Jing, X., Leser, G. P., et al. (2010) · Cell · doi:10.1016/j.cell.2010.08.029 · Cited by 517 · see citing works

Probing Lipid Mobility of Raft-exhibiting Model Membranes by Fluorescence Correlation Spectroscopy

Kahya, N., Scherfeld, D., Bacia, K., Poolman, B., & Schwille, P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302969200 · Cited by 499 · see citing works

Pathogens: raft hijackers

Mañes, S., del Real, G., & Martínez‐A, C. (2003) · Nature reviews. Immunology · doi:10.1038/nri1129 · Cited by 478 · see citing works

The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

Barrett, P. J., Song, Y., Horn, W. D. V., Hustedt, E. J., Schafer, J. M., Hadziselimovic, A., Beel, A. J., & Sanders, C. R. (2012) · Science · doi:10.1126/science.1219988 · Cited by 472 · see citing works

Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster

Sieber, J. J., Willig, K. I., Kutzner, C., Gerding‐Reimers, C., Harke, B., Donnert, G., Rammner, B., Eggeling, C., Hell, S. W., Grubmüller, H., et al. (2007) · Science · doi:10.1126/science.1141727 · Cited by 462 · see citing works

Cholesterol as Modulator of Receptor Function

Gimpl, G., Bürger, K., & Fahrenholz, F. (1997) · Biochemistry · doi:10.1021/bi963138w · Cited by 454 · see citing works

Influenza Viruses Select Ordered Lipid Domains during Budding from the Plasma Membrane

Scheiffele, P., Rietveld, A. G., Wilk, T., & Simons, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.4.2038 · Cited by 448 · see citing works

The influence of cholesterol on phospholipid membrane curvature and bending elasticity

Chen, Z., & Rand, R. P. (1997) · Biophysical Journal · doi:10.1016/s0006-3495(97)78067-6 · Cited by 433 · see citing works

SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis

Chamberlain, L. H., Burgoyne, R. D., & Gould, G. W. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.091502398 · Cited by 432 · see citing works

Effect of Line Tension on the Lateral Organization of Lipid Membranes

García‐Sáez, A. J., Chiantia, S., & Schwille, P. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706162200 · Cited by 386 · see citing works

Lipid Rafts and HIV Pathogenesis: Host Membrane Cholesterol Is Required for Infection by HIV Type 1

Liao, Z., Cimakasky, L. M., Hampton, R. A., Nguyen, D., & Hildreth, J. E. K. (2001) · AIDS Research and Human Retroviruses · doi:10.1089/088922201300343690 · Cited by 354 · see citing works

Domain-induced budding of vesicles

Jülicher, F., & Lipowsky, R. (1993) · Physical Review Letters · doi:10.1103/physrevlett.70.2964 · Cited by 352 · see citing works

Effect of cholesterol on structural and mechanical properties of membranes depends on lipid chain saturation

Pan, J., Tristram‐Nagle, S., & Nagle, J. F. (2009) · Physical Review E · doi:10.1103/physreve.80.021931 · Cited by 342 · see citing works

Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes

Sezgin, E., Levental, I., Grzybek, M., Schwarzmann, G. O. H., Mueller, V., Honigmann, A., Belov, V. N., Eggeling, C., Coskun, Ü., Simons, K., et al. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.03.007 · Cited by 335 · see citing works

Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide

Li, H., Yao, Z.-X., Degenhardt, B., Teper, G., & Papadopoulos, V. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.3.1267 · Cited by 317 · see citing works

Role of Cholesterol in the Formation and Nature of Lipid Rafts in Planar and Spherical Model Membranes

Crane, J. M., & Tamm, L. K. (2004) · Biophysical Journal · doi:10.1016/s0006-3495(04)74347-7 · Cited by 309 · see citing works

Observation of a Membrane Fusion Intermediate Structure

Yang, L., & Huang, H. W. (2002) · Science · doi:10.1126/science.1074354 · Cited by 307 · see citing works

Lateral diffusion in binary mixtures of cholesterol and phosphatidylcholines.

Rubenstein, J. L. R., Smith, B. A., & McConnell, H. M. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.15 · Cited by 300 · see citing works

Structure of Dipalmitoylphosphatidylcholine/Cholesterol Bilayer at Low and High Cholesterol Concentrations: Molecular Dynamics Simulation

Smondyrev, A. M., & Berkowitz, M. L. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77049-9 · Cited by 288 · see citing works

Cholesterol Perturbs Lipid Bilayers Nonuniversally

Pan, J., Mills, T. T., Tristram‐Nagle, S., et al. (2008) · Physical Review Letters · doi:10.1103/physrevlett.100.198103 · Cited by 287 · see citing works

Tuning lipid mixtures to induce or suppress domain formation across leaflets of unsupported asymmetric bilayers

Collins, M. D., & Keller, S. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702970105 · Cited by 274 · see citing works

Fusion peptides and the mechanism of viral fusion

Epand, R. M. (2003) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(03)00169-x · Cited by 270 · see citing works

Characterization of the Cholesterol Recognition Amino Acid Consensus Sequence of the Peripheral-Type Benzodiazepine Receptor

Jamin, N., Neumann, J., Ostuni, M. A., Vu, T. K. N., Yao, Z., Murail, S., Robert, J., Giatzakis, C., Papadopoulos, V., & Lacapère, J.-J. (2004) · Molecular Endocrinology · doi:10.1210/me.2004-0308 · Cited by 254 · see citing works

Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor

Baier, C. J., Fantini, J., & Barrantes, F. J. (2011) · Scientific Reports · doi:10.1038/srep00069 · Cited by 245 · see citing works

Modulation of phospholipid acyl chain order by cholesterol. A solid-state deuterium nuclear magnetic resonance study

Sankaram, M. B., & Thompson, T. E. (1990) · Biochemistry · doi:10.1021/bi00499a015 · Cited by 238 · see citing works

Membrane Fusion

Blumenthal, R., Clague, M. J., Durell, S. R., & Epand, R. M. (2002) · Chemical Reviews · doi:10.1021/cr000036+ · Cited by 226 · see citing works

Role for Influenza Virus Envelope Cholesterol in Virus Entry and Infection

Sun, X., & Whittaker, G. R. (2003) · Journal of Virology · doi:10.1128/jvi.77.23.12543-12551.2003 · Cited by 224 · see citing works

Transbilayer Effects of Raft-Like Lipid Domains in Asymmetric Planar Bilayers Measured by Single Molecule Tracking

Kiessling, V., Crane, J. M., & Tamm, L. K. (2006) · Biophysical Journal · doi:10.1529/biophysj.106.091421 · Cited by 221 · see citing works

Domain coupling in asymmetric lipid bilayers

Kiessling, V., Wan, C., & Tamm, L. K. (2008) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2008.09.003 · Cited by 217 · see citing works

Cholesterol reduction impairs exocytosis of synaptic vesicles

Linetti, A., Fratangeli, A., Taverna, E., Valnegri, P., Francolini, M., Cappello, V., Matteoli, M., Passafaro, M., & Rosa, P. (2010) · Journal of Cell Science · doi:10.1242/jcs.060681 · Cited by 209 · see citing works

Cholesterol Depletion of Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus with β-Cyclodextrin Inactivates and Permeabilizes the Virions: Evidence for Virion-Associated Lipid Rafts

Graham, D. R. M., Chertova, E. N., Hilburn, J. M., Arthur, L. O., & Hildreth, J. E. K. (2003) · Journal of Virology · doi:10.1128/jvi.77.15.8237-8248.2003 · Cited by 205 · see citing works

Mechanisms of Membrane Fusion

Zimmerberg, J. J., Vogel, S. S., & Chernomordik, L. (1993) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.bb.22.060193.002245 · Cited by 203 · see citing works

HIV gp41–mediated membrane fusion occurs at edges of cholesterol-rich lipid domains

Yang, S., Kiessling, V., Simmons, J. A., White, J. M., & Tamm, L. K. (2015) · Nature Chemical Biology · doi:10.1038/nchembio.1800 · Cited by 197 · see citing works

Membrane Cholesterol in the Function and Organization of G-Protein Coupled Receptors

Paila, Y. D., & Chattopadhyay, A. (2010) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-90-481-8622-8_16 · Cited by 195 · see citing works

Energetics of stalk intermediates in membrane fusion are controlled by lipid composition

Aeffner, S., Reusch, T., Weinhausen, B., & Salditt, T. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1119442109 · Cited by 185 · see citing works

Membrane fusion: a structural perspective on the interplay of lipids and proteins

Tamm, L. K., Crane, J. M., & Kiessling, V. (2003) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(03)00107-6 · Cited by 180 · see citing works

Cholesterol facilitates the native mechanism of Ca2+-triggered membrane fusion

Churchward, M. A., Rogasevskaia, T. P., Höfgen, J., Bau, J. T., & Coorssen, J. R. (2005) · Journal of Cell Science · doi:10.1242/jcs.02601 · Cited by 178 · see citing works

Proteins and cholesterol-rich domains

Epand, R. M. (2008) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2008.03.016 · Cited by 175 · see citing works

Identification of cholesterol recognition amino acid consensus (CRAC) motif in G-protein coupled receptors

Jafurulla, M., Tiwari, S., & Chattopadhyay, A. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.12.031 · Cited by 174 · see citing works

SNAREs Prefer Liquid-disordered over “Raft” (Liquid-ordered) Domains When Reconstituted into Giant Unilamellar Vesicles

Bacia, K., Schuette, C. G., Kahya, N., Jahn, R., & Schwille, P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407020200 · Cited by 171 · see citing works

Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains

Milovanović, D., Honigmann, A., Koike, S., Göttfert, F., Pähler, G., Junius, M., Müllar, S., Diederichsen, U., Janshoff, A., Grubmüller, H., et al. (2015) · Nature Communications · doi:10.1038/ncomms6984 · Cited by 168 · see citing works

Lipids and membrane microdomains in HIV-1 replication

Waheed, A. A., & Freed, E. O. (2009) · Virus Research · doi:10.1016/j.virusres.2009.04.007 · Cited by 164 · see citing works

An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic β cells

Sturek, J. M., Castle, J. D., Trace, A. P., PAGE, L. C., Castle, A. M., Evans‐Molina, C., Parks, J. S., Mirmira, R. G., & Hedrick, C. C. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41280 · Cited by 163 · see citing works

Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion

Yang, S., Kiessling, V., & Tamm, L. K. (2016) · Nature Communications · doi:10.1038/ncomms11401 · Cited by 159 · see citing works

Specific Lipids Supply Critical Negative Spontaneous Curvature—An Essential Component of Native Ca2+-Triggered Membrane Fusion

Churchward, M. A., Rogasevskaia, T. P., Brandman, D. M., Khosravani, H., Nava, P., Atkinson, J. K., & Coorssen, J. R. (2008) · Biophysical Journal · doi:10.1529/biophysj.107.123984 · Cited by 156 · see citing works

Cholesterol‐dependent balance between evoked and spontaneous synaptic vesicle recycling

Wasser, C. R., Ertunç, M., Liu, X., & Kavalali, E. T. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.123133 · Cited by 150 · see citing works

Measuring Lipid Asymmetry in Planar Supported Bilayers by Fluorescence Interference Contrast Microscopy

Crane, J. M., Kiessling, V., & Tamm, L. K. (2005) · Langmuir · doi:10.1021/la047654w · Cited by 148 · see citing works

Phase behavior of lipid mixtures

Feigenson, G. W. (2006) · Nature Chemical Biology · doi:10.1038/nchembio1106-560 · Cited by 146 · see citing works

The Principle of Membrane Fusion in the Cell (Nobel Lecture)

Rothman, J. E. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201402380 · Cited by 146 · see citing works

Manipulation of Cholesterol Levels in Rod Disk Membranes by Methyl-β-cyclodextrin

Niu, S., Mitchell, D. C., & Litman, B. J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200594200 · Cited by 140 · see citing works

Theory of thermal anomalies in the specific heat of lipid bilayers containing cholesterol

Ipsen, J. H., Mouritsen, O. G., & Zuckermann, M. J. (1989) · Biophysical Journal · doi:10.1016/s0006-3495(89)82713-4 · Cited by 137 · see citing works

SNARE proteins and ‘membrane rafts’

Lang, T. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.134346 · Cited by 130 · see citing works

Molecular Basis for the Glycosphingolipid-Binding Specificity of α-Synuclein: Key Role of Tyrosine 39 in Membrane Insertion

Fantini, J., & Yahi, N. (2011) · Journal of Molecular Biology · doi:10.1016/j.jmb.2011.03.009 · Cited by 129 · see citing works

Domain Registration in Raft-Mimicking Lipid Mixtures Studied Using Polymer-Tethered Lipid Bilayers

Garg, S., Rühe, J., Lüdtke, K., Jordan, R., & Naumann, C. A. (2006) · Biophysical Journal · doi:10.1529/biophysj.106.091082 · Cited by 127 · see citing works

Asymmetric GUVs Prepared by MβCD-Mediated Lipid Exchange: An FCS Study

Chiantia, S., Schwille, P., Klymchenko, A. S., et al. (2011) · Biophysical Journal · doi:10.1016/j.bpj.2010.11.051 · Cited by 125 · see citing works

Clustering of Syntaxin-1A in Model Membranes Is Modulated by Phosphatidylinositol 4,5-Bisphosphate and Cholesterol

Murray, D. H., & Tamm, L. K. (2009) · Biochemistry · doi:10.1021/bi9003217 · Cited by 121 · see citing works

Cholesterol as stabilizer of the oxytocin receptor

Gimpl, G., & Fahrenholz, F. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(02)00475-3 · Cited by 121 · see citing works

Single secretory granules of live cells recruit syntaxin-1 and synaptosomal associated protein 25 (SNAP-25) in large copy numbers

Knowles, M. K., Barg, S., Wan, L., Midorikawa, M., Chen, X., & Almers, W. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1014840107 · Cited by 117 · see citing works

The role of the lipid matrix for structure and function of the GPCR rhodopsin

Soubias, O., & Gawrisch, K. (2011) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2011.08.034 · Cited by 115 · see citing works

Fusion Activity of HIV gp41 Fusion Domain Is Related to Its Secondary Structure and Depth of Membrane Insertion in a Cholesterol-Dependent Fashion

Lai, A. L., Moorthy, A. M. E., Li, Y., et al. (2012) · Journal of Molecular Biology · doi:10.1016/j.jmb.2012.02.010 · Cited by 113 · see citing works

Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules

Kruit, J. K., Wijesekara, N., Fox, J. E. M., Dai, X.-Q., Brunham, L. R., Searle, G. J., Morgan, G. P., Costin, A. J., Tang, R., Bhattacharjee, A., et al. (2011) · Diabetes · doi:10.2337/db11-0081 · Cited by 113 · see citing works

A scissors mechanism for stimulation of SNARE-mediated lipid mixing by cholesterol

Tong, J., Borbat, P. P., Freed, J. H., & Shin, Y. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813138106 · Cited by 111 · see citing works

Roles of Cholesterol in Vesicle Fusion and Motion

Zhang, J., Xue, R., Ong, W., et al. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2009.06.025 · Cited by 107 · see citing works

Coupling of Cholesterol-Rich Lipid Phases in Asymmetric Bilayers

Wan, C., Kiessling, V., & Tamm, L. K. (2008) · Biochemistry · doi:10.1021/bi7021552 · Cited by 106 · see citing works

Impact of cholesterol on voids in phospholipid membranes

Falck, E., Patra, M., Karttunen, M., et al. (2004) · The Journal of Chemical Physics · doi:10.1063/1.1824033 · Cited by 105 · see citing works

Functional characterization of putative cholesterol binding sequence (CRAC) in human type‐1 cannabinoid receptor

Oddi, S., Dainese, E., Fezza, F., Lanuti, M., Barcaroli, D., Laurenzi, V. D., Centonze, D., & Maccarrone, M. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07041.x · Cited by 103 · see citing works

Impact of cholesterol on voids in phospholipid membranes

Falck, E., Patra, M., Karttunen, M. M., et al. (2004) · TU/e Research Portal · Cited by 102 · see citing works

Preparation of Artificial Plasma Membrane Mimicking Vesicles with Lipid Asymmetry

Lin, Q., & London, E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087903 · Cited by 96 · see citing works

Synaptic proteins and SNARE complexes are localized in lipid rafts from rat brain synaptosomes

Gil, C., Soler-Jover, A., Blasi, J., & Aguilera, J. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.01.111 · Cited by 90 · see citing works

In Situ Determination of Structure and Fluctuations of Coexisting Fluid Membrane Domains

Heftberger, P., Kollmitzer, B., Rieder, A. A., et al. (2015) · Biophysical Journal · doi:10.1016/j.bpj.2014.11.3488 · Cited by 89 · see citing works

Structure and function of membrane fusion peptides

Tamm, L. K., Han, X., Li, Y., & Lai, A. L. (2002) · Biopolymers · doi:10.1002/bip.10261 · Cited by 89 · see citing works

Cholesterol Promotes Hemifusion and Pore Widening in Membrane Fusion Induced by Influenza Hemagglutinin

Biswas, S., Yin, S., Blank, P. S., et al. (2008) · The Journal of General Physiology · doi:10.1085/jgp.200709932 · Cited by 80 · see citing works

Membrane cholesterol stabilizes the human serotonin1A receptor

Saxena, R., & Chattopadhyay, A. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.07.032 · Cited by 74 · see citing works

Membranes are not just rafts

Shaikh, S. R., & Edidin, M. A. (2006) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2006.06.017 · Cited by 73 · see citing works

Role of cholesterol in SNARE-mediated trafficking on intracellular membranes

Enrich, C., Rentero, C., Hierro, A., & Grewal, T. (2015) · Journal of Cell Science · doi:10.1242/jcs.164459 · Cited by 71 · see citing works

Molecular Mechanism of Cholesterol- and Polyphosphoinositide-Mediated Syntaxin Clustering

Murray, D. H., & Tamm, L. K. (2011) · Biochemistry · doi:10.1021/bi201307u · Cited by 66 · see citing works

Cholesterol Increases the Openness of SNARE-Mediated Flickering Fusion Pores

Stratton, B. S., Warner, J. M., Wu, Z., Nikolaus, J., Wei, G., Wagnon, E., Baddeley, D., Karatekin, E., & O’Shaughnessy, B. (2016) · Biophysical Journal · doi:10.1016/j.bpj.2016.02.019 · Cited by 63 · see citing works

Cholesterol Regulates Glucose-stimulated Insulin Secretion through Phosphatidylinositol 4,5-Bisphosphate

Hao, M., & Bogan, J. S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.038034 · Cited by 61 · see citing works

High Cholesterol Obviates a Prolonged Hemifusion Intermediate in Fast SNARE-Mediated Membrane Fusion

Kreutzberger, A. J. B., Kiessling, V., & Tamm, L. K. (2015) · Biophysical Journal · doi:10.1016/j.bpj.2015.06.022 · Cited by 57 · see citing works

Regulation of Membrane Proteins by Dietary Lipids: Effects of Cholesterol and Docosahexaenoic Acid Acyl Chain-Containing Phospholipids on Rhodopsin Stability and Function

Bennett, M. P., & Mitchell, D. C. (2008) · Biophysical Journal · doi:10.1529/biophysj.107.122788 · Cited by 50 · see citing works

Influence of Cholesterol on Catecholamine Release from the Fusion Pore of Large Dense Core Chromaffin Granules

Wang, N., Kwan, C., Gong, X., Chaves, E., Tse, A., & Tse, F. W. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4000-09.2010 · Cited by 47 · see citing works

Structural Influences: Cholesterol, Drug, and Proton Binding to Full-Length Influenza A M2 Protein

Ekanayake, E. V., Fu, R., & Cross, T. A. (2016) · Biophysical Journal · doi:10.1016/j.bpj.2015.11.3529 · Cited by 44 · see citing works

Hydrophobic Substitutions in the First Residue of the CRAC Segment of the gp41 Protein of HIV

Vishwanathan, S. A., Thomas, A., Brasseur, R., Epand, R. F., Hunter, E., & Epand, R. M. (2007) · Biochemistry · doi:10.1021/bi7018892 · Cited by 43 · see citing works

Fluorescence Microscopy to Study Domains in Supported Lipid Bilayers

Crane, J. M., & Tamm, L. K. (2007) · Methods in molecular biology · doi:10.1007/978-1-59745-519-0_32 · Cited by 40 · see citing works

Critical Role of Membrane Cholesterol in Exocytosis Revealed by Single Platelet Study

Ge, S., White, J. G., & Haynes, C. L. (2010) · ACS Chemical Biology · doi:10.1021/cb100130b · Cited by 39 · see citing works

Multiphasic Effects of Cholesterol on Influenza Fusion Kinetics Reflect Multiple Mechanistic Roles

Domańska, M. K., Wrona, D., & Kasson, P. M. (2013) · Biophysical Journal · doi:10.1016/j.bpj.2013.08.003 · Cited by 36 · see citing works

Counting the SNAREs needed for membrane fusion

van den Bogaart, G., & Jahn, R. (2011) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjr004 · Cited by 34 · see citing works

Vesicle fusion to planar membranes is enhanced by cholesterol and low temperature

Lee, D. E., Lew, M. G., & Woodbury, D. J. (2012) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2012.11.004 · Cited by 33 · see citing works

Identification of the LWYIK Motif Located in the Human Immunodeficiency Virus Type 1 Transmembrane gp41 Protein as a Distinct Determinant for Viral Infection

Chen, S. S.-L., Yang, P., Ke, P., et al. (2008) · Journal of Virology · doi:10.1128/jvi.01088-08 · Cited by 32 · see citing works

The SNARE Motif of Synaptobrevin Exhibits an Aqueous–Interfacial Partitioning That Is Modulated by Membrane Curvature

Liang, B., Dawidowski, D., Ellena, J. F., Tamm, L. K., & Cafiso, D. S. (2014) · Biochemistry · doi:10.1021/bi401638u · Cited by 30 · see citing works

Supported Lipid Bilayers as Models for Studying Membrane Domains

Kiessling, V., Yang, S., & Tamm, L. K. (2015) · Current topics in membranes · doi:10.1016/bs.ctm.2015.03.001 · Cited by 29 · see citing works

Protein-Lipid Interactions

Mateo, C. R., Gómez, J., Villalaín, J., et al. (2006) · Springer series in biophysics · doi:10.1007/3-540-28435-4 · Cited by 28 · see citing works

Where Biology Meets Physics—A Converging View on Membrane Microdomain Dynamics

Destainville, N., Schmidt, T. H., & Lang, T. (2015) · Current topics in membranes · doi:10.1016/bs.ctm.2015.10.004 · Cited by 28 · see citing works

Cholesterol effects on vesicle pools in chromaffin cells revealed by carbon-fiber microelectrode amperometry

Koseoglu, S., Love, S. A., & Haynes, C. L. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-011-5002-7 · Cited by 25 · see citing works

A cholesterol consensus motif is required for efficient intracellular transport and raft association of a group 2 HA from influenza virus

de Vries, M., Herrmann, A., & Veit, M. (2014) · Biochemical Journal · doi:10.1042/bj20141114 · Cited by 24 · see citing works

Hemagglutinin Spatial Distribution Shifts in Response to Cholesterol in the Influenza Viral Envelope

Domańska, M. K., Dunning, R. A., Dryden, K. A., et al. (2015) · Biophysical Journal · doi:10.1016/j.bpj.2015.09.014 · Cited by 21 · see citing works

Platelet membrane variations and their effects on δ-granule secretion kinetics and aggregation spreading among different species

Gruba, S. M., Koseoglu, S., Meyer, A. F., et al. (2015) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2015.04.006 · Cited by 19 · see citing works

Interplay of Proteins and Lipids in Virus Entry by Membrane Fusion

Lai, A. L., Li, Y., & Tamm, L. K. (2005) · doi:10.1002/3527606769.ch12 · Cited by 18 · see citing works

Capturing Glimpses of an Elusive HIV Gp41 Prehairpin Fusion Intermediate

Tamm, L. K., Lee, J., & Liang, B. (2014) · Structure · doi:10.1016/j.str.2014.08.010 · Cited by 14 · see citing works

Partitioning of Synaptotagmin I C2 Domains between Liquid-Ordered and Liquid-Disordered Inner Leaflet Lipid Phases

Wan, C., Kiessling, V., Cafiso, D. S., et al. (2011) · Biochemistry · doi:10.1021/bi101864k · Cited by 14 · see citing works

Variations in Fusion Pore Formation in Cholesterol-Treated Platelets

Finkenstaedt-Quinn, S. A., Gruba, S. M., & Haynes, C. L. (2016) · Biophysical Journal · doi:10.1016/j.bpj.2015.12.034 · Cited by 11 · see citing works

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

Chaudhary, N., Weissman, D., & Whitehead, K. A. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00283-5 · Cited by 1,555 · see citing works

Advances in COVID-19 mRNA vaccine development

Fang, E., Liu, X., Li, M., Zhang, Z., Song, L., Zhu, B., Wu, X., Liu, J., Zhao, D., & Li, Y. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00950-y · Cited by 601 · see citing works

Can Cholesterol Metabolism Modulation Affect Brain Function and Behavior?

Cartocci, V., Servadio, M., Trezza, V., & Pallottini, V. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.25488 · Cited by 77 · see citing works

Molecular‐scale structure of a high‐curvature membrane

Frost, A. S., Moss, F. R., Lincoff, J., et al. (2022) · The FASEB Journal · doi:10.1096/fasebj.2022.36.s1.0i126

The Language of Shape: Biological Reactions are Dramatically Affected by the Shape of Lipid Membranes

Stamou, D. G. (2010) · Biophysical Journal · doi:10.1016/j.bpj.2009.12.3378

Membrane shape as determinant of protein properties

Bozelli, J. C., Aulakh, S. S., & Epand, R. M. (2021) · Biophysical Chemistry · doi:10.1016/j.bpc.2021.106587 · Cited by 36 · see citing works

Interplay between Curvature and Lateral Organization of Lipids and Peptides/Proteins in Model Membranes

Wu, Q.-Y., & Liang, Q. D. (2014) · Langmuir · doi:10.1021/la4039123 · Cited by 23 · see citing works

Curvature and spatial organization in biological membranes

Parthasarathy, R., & Groves, J. T. (2006) · Soft Matter · doi:10.1039/b608631d · Cited by 125 · see citing works