Association between dietary fiber intake and risk of coronary heart disease: A meta-analysis
Abstract
Background & aims The association between coronary heart disease (CHD) and dietary fiber intake is not consistent, especially for the subtypes of dietary fiber. The aim of our study was to conduct a meta-analysis of existing cohort published studies assessing the association between dietary fiber intake and risk of CHD, and quantitatively estimating their dose-response relationships.Methods We searched PubMed and EMBASE before May 2013. Random-effect model was used to calculate the pool relative risk (RRs) for the incidence and mortality of CHD. Dose-response, subgroup analyses based on fiber subtypes, heterogeneity and publication bias were also carried out.Results Eighteen studies involving 672,408 individuals were finally included in the present study. The pooled-adjusted RRs of coronary heart disease for the highest versus lowest category of fiber intake were 0.93 (95% confidence interval (CI), 0.91-0.96, P < 0.001) for incidence of all coronary events and 0.83 (95% CI, 0.76-0.91, P < 0.001) for mortality. Further subgroup analyses based on fiber subtypes (cereal, fruit, and vegetable fiber), indicated that RRs were 0.92 (95% CI, 0.85-0.99, P = 0.032), 0.92 (95% CI, 0.86-0.98, P = 0.01), 0.95 (95% CI, 0.89-1.01, P = 0.098) respectively for all coronary event and 0.81 (95% CI, 0.72-0.92, P = 0.001), 0.68 (95% CI, 0.43-1.07, P = 0.094), 0.91 (95% CI, 0.74-1.12, P = 0.383) for mortality. In addition, a significant dose-response relationship was observed between fiber intake and the incidence and mortality of CHD (P < 0.001).Conclusions Our results indicate that consumption of dietary fiber is inversely associated with risk of coronary heart disease, especially for fiber from cereals and fruits. Besides, soluble and insoluble fibers have the similar effect. A significant dose-response relationship is also observed between fiber intake and CHD risk.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The quality of carbohydrate-rich foods is linked to cardiometabolic risk.
“the quality of carbohydrate-rich foods is linked to risk (Figure 6, Figure 7).152-160”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [159]
The quality of carbohydrate-rich foods is linked to cardiometabolic risk.
“the quality of carbohydrate-rich foods is linked to risk (Figure 6, Figure 7).152-160”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [160]
Total carbohydrate consumption has little relation to cardiometabolic health.
“While total carbohydrate consumption has little relation to cardiometabolic health, the quality of carbohydrate-rich foods is linked to risk (Figure 6, Figure 7).152-160”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [160]
Total carbohydrate consumption has little relation to cardiometabolic health.
“While total carbohydrate consumption has little relation to cardiometabolic health, the quality of carbohydrate-rich foods is linked to risk (Figure 6, Figure 7).152-160”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [159]
Poor quality carbohydrates are associated with long-term weight gain, diabetes, and CVD.
“Consistent with this constellation of adverse effects, poor quality carbohydrates are associated with long-term weight gain, diabetes, and CVD.29, 89, 158, 167”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [160]
Poor quality carbohydrates are associated with long-term weight gain, diabetes, and CVD.
“Consistent with this constellation of adverse effects, poor quality carbohydrates are associated with long-term weight gain, diabetes, and CVD.29, 89, 158, 167”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [159]
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · see citing works
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859 · see citing works
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763 · see citing works
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.005 · Cited by 19,575 · see citing works
Stang, A. (2010) · European Journal of Epidemiology · doi:10.1007/s10654-010-9491-z · Cited by 17,396 · see citing works
Cholesterol-lowering effects of dietary fiber: a meta-analysis
Brown, L., Rosner, B., Willett, W. W., & Sacks, F. M. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.1.30 · Cited by 1,857 · see citing works
WHO MONICA Project Principal Invest (1988) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(88)90084-4 · Cited by 1,798 · see citing works
Low Density Lipoprotein Oxidation and Its Pathobiological Significance
Steinberg, D. H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.34.20963 · Cited by 1,643 · see citing works
Optimal Diets for Prevention of Coronary Heart Disease
Hu, F. B. (2002) · JAMA · doi:10.1001/jama.288.20.2569 · Cited by 1,503 · see citing works
Kornitzer, M., Berghmans, L., Wilmet, M. D., Darquennes, H., Lagasse, R., & Payen, R. (1988) · Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) · Cited by 1,270 · see citing works
Generalized Least Squares for Trend Estimation of Summarized Dose–response Data
Orsini, N., Bellocco, R., & Greenland, S. (2006) · The Stata Journal Promoting communications on statistics and Stata · doi:10.1177/1536867x0600600103 · Cited by 1,245 · see citing works
Liu, S., Willett, W. C., Stampfer, M. J., Hu, F. B., Franz, M., Sampson, L., Hennekens, C. H., & Manson, J. E. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.6.1455 · Cited by 1,166 · see citing works
Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus.
Chandalia, M., Garg, A., Lütjohann, D., von Bergmann, K., Grundy, S., & Brinkley, L. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005113421903 · Cited by 1,158 · see citing works
Dietary Antioxidant Vitamins and Death from Coronary Heart Disease in Postmenopausal Women
Kushi, L. H., Folsom, A. R., Prineas, R. J., Mink, P. J., Wu, Y. G., & Bostick, R. M. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605023341803 · Cited by 959 · see citing works
Self-citationVegetable, Fruit, and Cereal Fiber Intake and Risk of Coronary Heart Disease Among Men
Rimm, E. B. (1996) · JAMA · doi:10.1001/jama.1996.03530300031036 · Cited by 889 · see citing works
A Possible Protective Effect of Nut Consumption on Risk of Coronary Heart Disease
Fraser, G. E. (1992) · Archives of Internal Medicine · doi:10.1001/archinte.152.7.1416 · Cited by 730 · see citing works
Fraser, G., Sabaté, J., Beeson, W., & Strahan, T. (1992) · Archives of Internal Medicine · doi:10.1001/archinte.1992.00400190054010 · Cited by 727 · see citing works
Antioxidant Vitamin Intake and Coronary Mortality in a Longitudinal Population Study
Knekt, P., Reunanen, A., Jävinen, R., Seppänen, R., Heliövaara, M., & Aromaa, A. J. (1994) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116964 · Cited by 635 · see citing works
Dietary Fiber and Risk of Coronary Heart Disease: A Pooled Analysis of Cohort Studies
Pereira, M. A., O'Reilly, E., Augustsson, K., Fraser, G. E., Goldbourt, U., Heitmann, B. L., Hallmans, G., Knekt, P., Liu, S., Pietinen, P., et al. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.4.370 · Cited by 630 · see citing works
Liu, S., Manson, J. E., Buring, J. E., Stampfer, M. J., Willett, W. C., & Ridker, P. M. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/75.3.492 · Cited by 594 · see citing works
Long-term Intake of Dietary Fiber and Decreased Risk of Coronary Heart Disease Among Women
Wolk, A. (1999) · JAMA · doi:10.1001/jama.281.21.1998 · Cited by 432 · see citing works
Intake of Dietary Fiber and Risk of Coronary Heart Disease in a Cohort of Finnish Men
Pietinen, P., Rimm, E. B., Korhonen, P. A., Hartman, A. M., Willett, W. C., Albanes, D., & Virtamo, J. R. K. (1996) · Circulation · doi:10.1161/01.cir.94.11.2720 · Cited by 345 · see citing works
Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men
Jensen, M. K., Koh-Banerjee, P., Hu, F. B., FRANZ, M. M., Sampson, L., Grønbæk, M., & Rimm, E. B. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.6.1492 · Cited by 338 · see citing works
Glycemic Exposure Is Associated With Reduced Pulmonary Function in Type 2 Diabetes
Davis, W. A., Knuiman, M. W., Kendall, P. A., Grange, V., & Davis, T. M. E. (2004) · Diabetes Care · doi:10.2337/diacare.27.3.752 · Cited by 323 · see citing works
Barefoot, J. C., Larsen, S., von der Lieth, L., & Schroll, M. (1995) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a117663 · Cited by 285 · see citing works
A prospective study of dietary fiber intake and risk of cardiovascular disease among women
Liu, S., Buring, J. E., Sesso, H. D., Rimm, E. B., Willett, W. C., & Manson, J. E. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01695-3 · Cited by 272 · see citing works
Dietary Fiber Intake and Reduced Risk of Coronary Heart Disease in US Men and Women
Bazzano, L., He, J., Ogden, L. G., Loria, C. M., & Whelton, P. K. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.16.1897 · Cited by 262 · see citing works
Association between Glycemic State and Lung Function: The Framingham Heart Study
Walter, R. E., Beiser, A., Givelber, R. J., O’Connor, G. T., & Gottlieb, D. J. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2203022 · Cited by 254 · see citing works
A strategy for modelling the effect of a continuous covariate in medicine and epidemiology.
Royston, P. (2000) · Statistics in Medicine · doi:10.1002/1097-0258(20000730)19:14 · Cited by 234 · see citing works
Physical activity and incidence of coronary heart disease in middle-aged women and men
FOLSOM, A. R., Arnett, D. K., Hutchinson, R. G., LIAO, F., Clegg, L. X., & COOPER, L. S. (1997) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199707000-00009 · Cited by 231 · see citing works
Interaction of dietary antioxidants in vivo: how fruit and vegetables prevent disease?
Eastwood, M. A. (1999) · QJM · doi:10.1093/qjmed/92.9.527 · Cited by 219 · see citing works
Streppel, M. T., Ocké, M. C., Boshuizen, H. C., Kok, F. J., & Kromhout, D. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.4.1119 · Cited by 170 · see citing works
Cholesterol-lowering Effects of Dietary Fiber
Ikemoto, S. (2000) · Journal of Japanese Association for Dietary Fiber Research · doi:10.11217/jjdf1997.4.1 · Cited by 162 · see citing works
Eshak, E. S., Iso, H., Date, C., Kikuchi, S., Watanabe, Y., Wada, Y., Wakai, K., & Tamakoshi, A. (2010) · Journal of Nutrition · doi:10.3945/jn.110.122358 · Cited by 159 · see citing works
Triglycerides and Risk for Coronary Heart Disease
McBride, P. E. (2007) · JAMA · doi:10.1001/jama.298.3.336 · Cited by 134 · see citing works
Effects of Whole Grains on Coronary Heart Disease Risk
Harris, K. A., & Kris‐Etherton, P. M. (2010) · Current Atherosclerosis Reports · doi:10.1007/s11883-010-0136-1 · Cited by 134 · see citing works
Major Cereal Grain Fibers and Psyllium in Relation to Cardiovascular Health
Bernstein, A., Titgemeier, B., Kirkpatrick, K., Golubić, M., & Roizen, M. F. (2013) · Nutrients · doi:10.3390/nu5051471 · Cited by 109 · see citing works
Nutrition Protocols for the Prevention of Cardiovascular Disease
Retelny, V. S., Neuendorf, A., & Roth, J. L. (2008) · Nutrition in Clinical Practice · doi:10.1177/0884533608323425 · Cited by 70 · see citing works
Kokubo, Y., Iso, H., Saito, I., Yamagishi, K., Ishihara, J., Inoue, M., Tsugane, S., & for the JPHC Study Group (2011) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2011.100 · Cited by 69 · see citing works
Wallström, P., Sonestedt, E., Hlebowicz, J., Ericson, U., Drake, I., Persson, M., Gullberg, B., Hedblad, B., & Wirfält, E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031637 · Cited by 68 · see citing works
Leander, K., Wiman, B., Hallqvist, J., Andersson, T., Ahlbom, A., & Fairé, U. D. (2007) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e328012e3cc · Cited by 45 · see citing works
Dietary fibre and cardiovascular disease mortality in the UK Women’s Cohort Study
Threapleton, D. E., Greenwood, D. C., Burley, V. J., Aldwairji, M. A., & Cade, J. E. (2013) · European Journal of Epidemiology · doi:10.1007/s10654-013-9799-6 · Cited by 35 · see citing works
Dietary fiber and coronary disease: Does the evidence support an association?
Lupton, J. R., & Turner, N. D. (2003) · Current Atherosclerosis Reports · doi:10.1007/s11883-003-0041-y · Cited by 31 · see citing works
Srimahachota, S., Wunsuwan, R., Siritantikorn, A., Boonla, C., Chaiwongkarjohn, S., & Tosukhowong, P. (2010) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2010.04.056 · Cited by 27 · see citing works
Implications of cost in treatment selection for patients with coronary heart disease
Mark, D. B. (1996) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(95)01077-7 · Cited by 26 · see citing works
Nutrition and Cardiovascular Disease
Michael M., M. J. (2014) · CRC Press eBooks · doi:10.1201/b17616-14 · Cited by 24 · see citing works
Ward, H. A., Keogh, R. H., Lentjes, M. A. H., Luben, R., Wareham, N. J., & Khaw, K. (2011) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2011.184 · Cited by 20 · see citing works
Nutrition and Cardiovascular Disease.
(1977) · Annals of Internal Medicine · doi:10.7326/0003-4819-86-6-836_3 · Cited by 18 · see citing works
Percutaneous coronary intervention versus medical therapy for coronary heart disease
Maron, D. J. (2000) · Current Atherosclerosis Reports · doi:10.1007/s11883-000-0061-9 · Cited by 12 · see citing works
Risk management of coronary heart disease – prevention
Dorner, T. E., & Rieder, A. (2004) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-004-0073-0 · Cited by 12 · see citing works
Coronary Heart Disease in the Elderly: Management Considerations.
Friesinger, G. C. (1994) · PubMed · Cited by 5 · see citing works
Glycaemic and insulinaemic index of meals in stable obstructive pulmonary disease subjects.
Eliraz, A., Sternfeld, M., & Madar, Z. (1994) · PubMed · Cited by 5 · see citing works
Flagged first, then by citations
1 of the 55 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Mozaffarian, D. (2016) · Circulation · doi:10.1161/circulationaha.115.018585 · Cited by 2,216 · see citing works
Dietary fiber and health outcomes: an umbrella review of systematic reviews and meta-analyses
Veronese, N., Solmi, M., Caruso, M. G., Giannelli, G., Osella, A. R., Evangelou, E., Maggi, S., Fontana, L., Stubbs, B., & Tzoulaki, I. (2018) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqx082 · Cited by 536 · see citing works
Gordillo‐Bastidas, E., & Díaz‐Rizzolo, D. A. (2016) · Journal of Nutrition & Food Sciences · doi:10.4172/2155-9600.1000497 · Cited by 227 · see citing works
Kim, Y., & Je, Y. (2016) · Archives of Cardiovascular Diseases · doi:10.1016/j.acvd.2015.09.005 · Cited by 212 · see citing works
McRae, M. P. (2017) · Journal of Chiropractic Medicine · doi:10.1016/j.jcm.2017.05.005 · Cited by 184 · see citing works
Impact of plant extracts upon human health: A review
Veiga, M., Costa, E. M., Silva, S., & Pintado, M. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1540969 · Cited by 177 · see citing works
Partula, V., Deschasaux, M., Druesne-Pecollo, N., Latino-Martel, P., Desmetz, E., Chazelas, E., Kesse-Guyot, E., Julia, C., Fezeu, L. K., Galan, P., et al. (2020) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa063 · Cited by 133 · see citing works
McKeown, N. M., Fahey, G. C., Jr., Slavin, J. L., & van der Kamp, J. W. (2022) · BMJ · doi:10.1136/bmj-2020-054370 · Cited by 133 · see citing works
Dietary fiber intake and risk of metabolic syndrome: A meta-analysis of observational studies
Wei, B., Liu, Y., Lin, X., Fang, Y., Cui, J., & Wan, J. (2017) · Clinical Nutrition · doi:10.1016/j.clnu.2017.10.019 · Cited by 112 · see citing works
Potential Impact of Time Trend of Life-Style Factors on Cardiovascular Disease Burden in China
Li, Y., Wang, D. D., Ley, S. H., Howard, A. G., He, Y., Lu, Y., Danaei, G., & Hu, F. B. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.06.011 · Cited by 107 · see citing works
Wu, L., Sun, D., & He, Y. (2016) · Journal of Human Hypertension · doi:10.1038/jhh.2016.44 · Cited by 105 · see citing works
Bergeron, N., Williams, P. T., Lamendella, R., Faghihnia, N., Grube, A., Li, X., Wang, Z., Knight, R. D., Jansson, J. K., Hazen, S. L., et al. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114516004165 · Cited by 101 · see citing works
Diet and Cardiovascular Disease: Advances and Challenges in Population-Based Studies
Pan, A., Lin, X., Hemler, E. C., & Hu, F. B. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.02.017 · Cited by 96 · see citing works
Dietary Fibre as a Unifying Remedy for the Whole Spectrum of Obesity-Associated Cardiovascular Risk
Bozzetto, L., Costabile, G., Pepa, G. D., Ciciola, P., Vetrani, C., Vitale, M., Rivellese, A. A., & Annuzzi, G. (2018) · Nutrients · doi:10.3390/nu10070943 · Cited by 93 · see citing works
Role of diet and exercise in aging, Alzheimer’s disease, and other chronic diseases
Khemka, S., Reddy, A., Garcia, R. I., Jacobs, M., Reddy, R. P., Roghani, A. K., Pattoor, V., Basu, T., Sehar, U., & Reddy, P. H. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102091 · Cited by 88 · see citing works
Mäkinen, O. E., Sözer, N., Ercili-Cura, D., & Poutanen, K. S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802778-3.00006-8 · Cited by 86 · see citing works
Yan, Z., Zhang, X., Li, C., Jiao, S., & Dong, W. (2017) · European Journal of Preventive Cardiology · doi:10.1177/2047487316686441 · Cited by 82 · see citing works
Antioxidant Activity of Oat Proteins Derived Peptides in Stressed Hepatic HepG2 Cells
Du, Y., Esfandi, R., Willmore, W. G., & Tsopmo, A. (2016) · Antioxidants · doi:10.3390/antiox5040039 · Cited by 74 · see citing works
Ramezani, F., Pourghazi, F., Eslami, M., Gholami, M., Khonsari, N. M., Ejtahed, H., Larijani, B. A., & Qorbani, M. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.11.005 · Cited by 80 · see citing works
Dietary Fiber and Telomere Length in 5674 U.S. Adults: An NHANES Study of Biological Aging
Tucker, L. A. (2018) · Nutrients · doi:10.3390/nu10040400 · Cited by 69 · see citing works
Technological Evaluation of Fiber Effects in Wheat-Based Dough and Bread
Verbeke, C., Debonne, E., Versele, S., Bockstaele, F. V., & Eeckhout, M. (2024) · Foods · doi:10.3390/foods13162582 · Cited by 72 · see citing works
Ahmed, I. A. M., Juhaimi, F. A., & Özcan, M. M. (2021) · International Journal of Food Science & Technology · doi:10.1111/ijfs.15011 · Cited by 64 · see citing works
Origen, componentes y posibles mecanismos de acción de la dieta mediterránea
Urquiaga, I., Echeverría, G., Catalina Dussaillant, K., & Rigotti, A. (2017) · Revista médica de Chile · doi:10.4067/s0034-98872017000100012 · Cited by 61 · see citing works
Protein From Oat: Structure, Processes, Functionality, and Nutrition
Mäkinen, O. E., Ercili-Cura, D., Poutanen, K. S., Holopainen‐Mantila, U., Lehtinen, P., & Sözer, N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-91652-3.00006-x · Cited by 56 · see citing works
A Heart-Healthy Diet: Recent Insights and Practical Recommendations
Dinu, M., Pagliai, G., & Sofi, F. (2017) · Current Cardiology Reports · doi:10.1007/s11886-017-0908-0 · Cited by 51 · see citing works
Dietary Patterns, Alcohol Consumption and Risk of Coronary Heart Disease in Adults: A Meta-Analysis
Zhang, X., Shu, L., Si, C., Yu, X., Liao, D., Gao, W., Zhang, L., & Zheng, P.-F. (2015) · Nutrients · doi:10.3390/nu7085300 · Cited by 51 · see citing works
Li, B., Zhang, G., Tan, M., Zhao, L., Jin, L., Tang, X., Jiang, G., & Zhong, K. (2016) · Medicine · doi:10.1097/md.0000000000004229 · Cited by 51 · see citing works
Utilization of Plant Dietary Fibers to Reinforce Low-Calorie Dairy Dessert Structure
Staffolo, M. D., Sato, A. C. K., & Cunha, R. L. (2017) · Food and Bioprocess Technology · doi:10.1007/s11947-017-1872-9 · Cited by 48 · see citing works
Veronese, N., Gianfredi, V., Solmi, M., Barbagallo, M., Dominguez, L. J., Mandalà, C., Palermo, C. D., Carruba, L., Solimando, L., Stubbs, B., et al. (2025) · Clinical Nutrition · doi:10.1016/j.clnu.2025.06.021 · Cited by 47 · see citing works
Influence of Bioactive Nutrients on the Atherosclerotic Process: A Review
Casas, R. M., Estruch, R., & Sacanella, E. (2018) · Nutrients · doi:10.3390/nu10111630 · Cited by 44 · see citing works
Phillips, K. M., Haytowitz, D. B., & Pehrsson, P. R. (2019) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2019.103253 · Cited by 44 · see citing works
Bioactives in Cocoa: Novel Findings, Health Benefits, and Extraction Techniques
Tušek, K., Valinger, D., Jurina, T., Cvetnić, T. S., Kljusurić, J. G., & Benković, M. (2024) · Separations · doi:10.3390/separations11040128 · Cited by 43 · see citing works
Moreno‐Franco, B., Latre, M. L., Esteban, E. M. A., Ordovás, J. M., Casasnovas, J. A., & Peñalvo, J. L. (2014) · PubMed · doi:10.3305/nh.2014.30.6.7778 · Cited by 39 · see citing works
Zhao, J., Cheng, W., Lu, H., Shan, A., Zhang, Q., Sun, X., Kang, L., Xie, J., & Xu, B. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1046912 · Cited by 36 · see citing works
Aoe, S., Yamanaka, C., Ohtoshi, H., Nakamura, F., & Fujiwara, S. (2021) · Marine Drugs · doi:10.3390/md19070352 · Cited by 32 · see citing works
Menezes, E. G. T., Oliveira, É. R., Carvalho, G. R., Guimarães, I. C., & Queiroz, F. (2019) · Food Science and Technology · doi:10.1590/fst.22918 · Cited by 30 · see citing works
Verdú, S., Baviera, J. M. B., & Grau, R. (2017) · LWT · doi:10.1016/j.lwt.2017.06.007 · Cited by 30 · see citing works
The Effect of Diet on Cardiovascular Disease and Lipid and Lipoprotein Levels
Feingold, K. R. (2021) · Europe PMC (PubMed Central) · Cited by 30 · see citing works
Dominguez, L. J., Bes‐Rastrollo, M., Toledo, E., Gea, A., Fresán, U., Barbagallo, M., & Martínez‐González, M. Á. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1846-3 · Cited by 28 · see citing works
Gustafson, C. R., & Rose, D. J. (2022) · Nutrients · doi:10.3390/nu14112341 · Cited by 28 · see citing works
Buil‐Cosiales, P., Martínez‐González, M. Á., Ruiz‐Canela, M., Díez‐Espino, J., García‐Arellano, A., & Toledo, E. (2017) · Nutrients · doi:10.3390/nu9030295 · Cited by 27 · see citing works
Zavala, G. A., Ainscough, T., & Jimenez‐Moreno, C. (2022) · Nutrition Bulletin · doi:10.1111/nbu.12568 · Cited by 25 · see citing works
Lim, S. H., Kim, Y., Yun, K. N., Kim, J. Y., Jang, J., Han, M., & Lee, J. (2016) · Scientific Reports · doi:10.1038/srep38728 · Cited by 25 · see citing works
Lim, S. H. (2017) · Journal of Medicinal Food · doi:10.1089/jmf.2016.3886 · Cited by 25 · see citing works
Barrett, E. M., Amoutzopoulos, B., Batterham, M. J., Ray, S., & Beck, E. J. (2020) · Public Health Nutrition · doi:10.1017/s1368980019004221 · Cited by 25 · see citing works
Perez‐Cornago, A., Crowe, F. L., Appleby, P. N., Bradbury, K. E., Wood, A., Jakobsen, M. U., Johnson, L., Sacerdote, C., Steur, M., Weiderpass, E., et al. (2020) · International Journal of Epidemiology · doi:10.1093/ije/dyaa155 · Cited by 24 · see citing works
Effects of cereal soluble dietary fibres on hydrolysis of p-nitrophenyl laurate by pancreatin
Zhai, H., Gunness, P., & Gidley, M. J. (2016) · Food & Function · doi:10.1039/c6fo00383d · Cited by 23 · see citing works
Navaei, N., Pourafshar, S., Akhavan, N. S., Litwin, N. S., Foley, E., George, K. S., Hartley, S. C., Elam, M. L., Rao, S., Arjmandi, B. H., et al. (2019) · Food & Function · doi:10.1039/c8fo01890a · Cited by 24 · see citing works
Mann, K. D., Pearce, M. S., & Seal, C. J. (2016) · Proceedings of The Nutrition Society · doi:10.1017/s0029665116000793 · Cited by 22 · see citing works
Noguti, J., Chan, A. A., Bandera, B. C., Brislawn, C., Protić, M., Sim, M., Jansson, J. K., Bilchik, A. J., & Lee, D. J. (2018) · Oncotarget · doi:10.18632/oncotarget.25276 · Cited by 21 · see citing works
Mirrafiei, A., Jayedi, A., & Shab‐Bidar, S. (2023) · Food & Function · doi:10.1039/d2fo04024g · Cited by 18 · see citing works
Physicochemical properties and microstructure of corn flour–cellulose fiber extrudates
Zhao, Y., Zhao, C., Tang, X., Zhou, J., Li, H., Zhang, H., & Liu, J. (2021) · Food Science & Nutrition · doi:10.1002/fsn3.2195 · Cited by 19 · see citing works
Anthropometrics, diet, and resting energy expenditure in Norwegian adults with achondroplasia
Madsen, A., Fredwall, S. O., Månum, G., Henriksen, C., & Slettahjell, H. B. (2019) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.61272 · Cited by 19 · see citing works
Kenney, E., Adebiyi, V. O., Seligman, H. K., Ehmke, M. D., Guthrie, J. F., Coleman‐Jensen, A., & Frongillo, E. A. (2024) · Current Nutrition Reports · doi:10.1007/s13668-024-00547-7 · Cited by 17 · see citing works
Egg, S., Erler, J., Perktold, B., Hasenegger, V., Rust, P., Ramoner, R. E., König, J. S., & Purtscher, A. E. (2018) · Public Health Nutrition · doi:10.1017/s1368980018003270 · Cited by 17 · see citing works
Application of nutrient essentiality criteria to dietary carbohydrates
Tondt, J., Yancy, W. S., & Westman, E. C. (2020) · Nutrition Research Reviews · doi:10.1017/s0954422420000050 · Cited by 17 · see citing works
Jabbari, M., Eini‐Zinab, H., Safaei, E., Poursoleiman, F., Amini, B., Babashahi, M., Barati, M., & Hekmatdoost, A. (2022) · Nutrition Research · doi:10.1016/j.nutres.2022.12.011 · Cited by 16 · see citing works
Models to Evaluate the Prebiotic Potential of Foods
Aquino, J. D. S., Batista, K. S., Menezes, F. N. D. D., Lins, P. P., Gomes, J. A. D. S., & da Silva, L. A. (2017) · InTech eBooks · doi:10.5772/intechopen.69174 · Cited by 16 · see citing works
Verdú, S., Baviera, J. M. B., & Grau, R. (2019) · Food Control · doi:10.1016/j.foodcont.2019.02.004 · Cited by 14 · see citing works
Song, S., & Song, Y. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1871-2 · Cited by 13 · see citing works
Figueroa, L. E., & Genovese, D. B. (2019) · Journal of Food Science and Technology · doi:10.1007/s13197-019-04199-2 · Cited by 11 · see citing works
Muñoz-Cabrejas, A., Laclaustra, M., Guallar‐Castillón, P., Casasnovas, J. A., Jarauta, E., Sandoval‐Insausti, H., Donat‐Vargas, C., & Moreno‐Franco, B. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.04.049 · Cited by 11 · see citing works
ANALISIS KANDUNGAN GIZI DAN AKTIVITAS ANTIOKSIDAN ES KRIM NANAS MADU
Chauliyah, A. I. N., & Murbawani, E. A. (2015) · Journal of Nutrition College · doi:10.14710/jnc.v4i4.10172 · Cited by 11 · see citing works
Mono- and disaccharides: Selected physicochemical and functional aspects
Jouppila, K. (2017) · Cited by 11 · see citing works
Overview of the Health Benefits of Adequate Fiber Intake
Dreher, M. L. (2017) · Springer eBooks · doi:10.1007/978-3-319-50557-2_2 · Cited by 11 · see citing works
Wang, W., Wang, Y., Gao, X., Zhao, Z., Li, L., Yu, B., Liu, G., & Lin, P. (2020) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2020.08.027 · Cited by 11 · see citing works
Harris, R. M., Rose, A. M., Forouhi, N. G., & Unwin, N. C. (2020) · Food Science & Nutrition · doi:10.1002/fsn3.1363 · Cited by 11 · see citing works
Park, Y. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802972-5.00020-2 · Cited by 11 · see citing works
Dietary interventions in cardiac rehabilitation – The gap between guidelines and clinical practice
Kristensen, M. B., Dieperink, K. B., Rossau, H. K., Egholm, C. L., Viggers, L., Bertelsen, B. M., & Zwisler, A. (2018) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2018.05.007 · Cited by 10 · see citing works
Diet, inflammation, and cardiovascular disease
Vahid, F., Chiriboga, D. E., Bohn, T., & Hébert, J. R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822130-3.00015-6 · Cited by 9 · see citing works
de Córdoba, U. N., Marchiori, G. N., González, A. L., de Córdoba, U. N., Perovic, N. R., de Córdoba, U. N., Defagó, M. D., & de Córdoba, U. N. (2017) · Perspectivas en Nutrición Humana · doi:10.17533/udea.penh.v19n1a07 · Cited by 7 · see citing works
Engineering and Health Benefits of Fruits and Vegetables Beverages
Veiga, M., Costa, E. M., Voss, G. B., Silva, S., & Pintado, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815270-6.00012-8 · Cited by 7 · see citing works
Pigmented Pseudocereals: Chemistry, Functionality, and Technological Aspects in Food Systems
Mehany, T., Taha, A., Olawoye, B. T., Korma, S. A., Popoola-Akinola, O. O., Esua, O. J., & Manzoor, M. F. (2023) · Royal Society of Chemistry eBooks · doi:10.1039/9781837670291-00144 · Cited by 6 · see citing works
da Silva, F. M. O., Pimenta, A. M., Juvanhol, L. L., Hermsdorff, H. H. M., & Bressan, J. (2025) · Nutrition · doi:10.1016/j.nut.2025.112711 · Cited by 6 · see citing works
Zhang, H., Lin, Z., Chen, J., Gan, D., Zhou, H., Ma, Z., Zeng, X., Xue, Y., Wang, X., Zhan, Q., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.893436 · Cited by 6 · see citing works
Aoe, S., Kawano, T., Naito, J., Nishida, N., & Takahashi, M. (2022) · Food Science & Nutrition · doi:10.1002/fsn3.3130 · Cited by 6 · see citing works
Dietary Fiber and Hyperlipidemia and Cardiovascular Disease
Tovar, A. R., Guevara‐Cruz, M., Serralde-Zúñiga, A. E., & Torres, N. (2020) · Food engineering series · doi:10.1007/978-3-030-38654-2_10 · Cited by 7 · see citing works
Ganbat, K., Ulzii, B. N., & Shin, S. (2024) · Epidemiology and Health · doi:10.4178/epih.e2024035 · Cited by 5 · see citing works
Wijaya, H., Hirata, Y., Tjan, L. H., Tjahjono, Y., Foe, K., Caroline, C., Setiadi, D. A., Wihadmadyatami, H., Novita, B. D., Jong, F. H. H., et al. (2022) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2022.101049 · Cited by 5 · see citing works
do Carmo, C. S., Costa, L., Serra, T., Knutsen, S. H., Sahlstrøm, S., & Bronze, M. R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821470-1.00010-0 · Cited by 5 · see citing works
Deciphering the Riddles in Nutrition and Cardiovascular Disease
Carro, A., & Panisello, J. M. (2019) · European Cardiology Review · doi:10.15420/ecr.2019.07 · Cited by 5 · see citing works
Magdy, M., Elsaeidy, S., & El-Nemr, M. (2023) · Zagazig Journal of Agricultural Research · doi:10.21608/zjar.2023.322980 · Cited by 4 · see citing works
Basnet, T. B., Srijana, G. C., Basnet, R., & Neupane, B. (2020) · PLoS ONE · doi:10.1371/journal.pone.0243063 · Cited by 4 · see citing works
Barb, J. J., King, L. C., Yang, S. B., Turner, S., Vizioli, C., Tyler, R. E., Chen, K. Y., Farokhnia, M., Wallen, G. R., & Leggio, L. (2025) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.70140 · Cited by 3 · see citing works
Effects of nutrition education on cardio-metabolic outcomes: A randomised clinical trial
Santos, H. D., Beeson, W. L., Segovia‐Siapco, G., Koranda, B., & Jehi, T. (2019) · Health Education Journal · doi:10.1177/0017896919887221 · Cited by 3 · see citing works
Factors associated with hypertension in women of child-bearing age in Abeokuta
Akinbule, O. O., Lovely, O. K., Omidiran, A. T., Adenusi, S. A., Lasabi, O. T., & Oladoyinbo, C. A. (2022) · Human Nutrition & Metabolism · doi:10.1016/j.hnm.2022.200160 · Cited by 3 · see citing works
Blake, R., Lating, J. M., & Everly, G. S. (2012) · Springer eBooks · doi:10.1007/978-1-4614-5538-7_18 · Cited by 3 · see citing works
Abdolghaffari, A. H., Farzaei, M. H., Lashgari, N., Roudsari, N. M., Haddadi, N., Singh, A. K., Rana, H. K., Pandey, A. K., & Momtaz, S. (2020) · Springer eBooks · doi:10.1007/978-981-15-3552-9_6 · Cited by 3 · see citing works
Night shift work, dietary patterns, and coronary heart disease
Nôga, D. A., Meth, E. M. S., Pacheco, A. P., Cedernaes, J., Xue, P., & Benedict, C. (2026) · European Journal of Epidemiology · doi:10.1007/s10654-026-01362-w · Cited by 2 · see citing works
Hartopo, A. B., Inggriani, M. P., Jhundy, B. W., Fachiroh, J., Rosha, P. T., Wardani, R. K., & Dewi, F. S. T. (2023) · Cardiovascular Prevention and Pharmacotherapy · doi:10.36011/cpp.2023.5.e3 · Cited by 2 · see citing works
Physiologic Effects of Isolated or Synthetic Dietary Fiber in Children: A Scoping Review
Chen, L., Avendano, E. E., Valderrama, A. V., Lan, J. J., Tye, D., Morin, R. A., Livingston, K. A., McKeown, N. M., & Nirmala, N. (2024) · Current Developments in Nutrition · doi:10.1016/j.cdnut.2023.102074 · Cited by 2 · see citing works
Jin, Q., Chen, S., & Ji, X. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1467889 · Cited by 2 · see citing works
Traditional versus Commercial Apple Varieties: Chemical Composition and Implications for Processing
Akagić, A., & Oras, A. (2025) · IntechOpen eBooks · doi:10.5772/intechopen.1008508 · Cited by 2 · see citing works
Fiber and Coronary Heart Disease
Dreher, M. L. (2017) · Springer eBooks · doi:10.1007/978-3-319-50557-2_13 · Cited by 2 · see citing works
Dietary fiber intake and the Mediterranean population
Dominguez, L. J., & Barbagallo, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818649-7.00023-0 · Cited by 2 · see citing works
Lipid profile in Polish women following lacto-ovo-vegetarian and vegan diets – preliminary study.
Gogga, P., Śliwińska, A., Aleksandrowicz‐Wrona, E., & Małgorzewicz, S. (2021) · Acta Biochimica Polonica · doi:10.18388/abp.2020_5653 · Cited by 2 · see citing works
Uses of multigrain for functional ice cream cone
Patil, U., & Singh, S. P. (2022) · International Journal of Horticulture and Food Science · doi:10.33545/26631067.2022.v4.i2c.121 · Cited by 1 · see citing works
Association between ischemic heart disease and dietary intake of lycopene: a case–control study
Amjadi, A., Alami, F., Mohammadian, M. K., Mirshafaei, S. R., Azaryan, F., Houshiarrad, A., Esmaeili, M., Shekari, S., Abdollahi, M., Khoshdooz, S., et al. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1281539 · Cited by 1 · see citing works
Dreher, M. L. (2017) · Springer eBooks · doi:10.1007/978-3-319-50557-2_16 · Cited by 1 · see citing works
Moore, R., Lating, J. M., & Everly, G. S. (2019) · Springer eBooks · doi:10.1007/978-1-4939-9098-6_22 · Cited by 1 · see citing works
- Authors
- Wu, Y., Qian, Y., Pan, Y., Li, P., Yang, J., Ye, X., & Xu, G.
- Affiliations
- Zhejiang University (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Corresponding author
- Ye, Xianhua
- Xu, Geng
- Venue
- Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2015-08
- Volume
- 34
- Issue
- 4
- Pages
- 603-611
- ISSN
- 0261-5614 (ISSN-L)
- OpenAlex
- W2143938233
- Cited by
- 128
- References
- 55
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 10 · 2023: 6 · 2022: 12 · 2021: 9 · 2020: 15 · 2019: 13 · 2018: 14 · 2017: 18 · 2016: 16 · 2015: 4 · 2014: 2 · 2012: 1
- FWCI
- 2.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (81302455)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- dietary fiber, coronary artery disease, cardiovascular risk, cereal fiber, fruit fiber, plant fibers, soluble dietary fiber, insoluble dietary fiber, dose-response relationship, coronary heart disease mortality, coronary heart disease incidence, cohort studies, publication bias, study heterogeneity, cardiovascular disease prevention, nutrition and disease prevention
- MeSH terms
- Edible Grain, Coronary Artery Disease, Dietary Fiber, Fruit, Humans, Risk Factors, Vegetables, Incidence, Databases, Factual
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
