Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Sarbassov, D. D., Guertin, D. A., Ali, S. M., & Sabatini, D. M. (2005) · Science · doi:10.1126/science.1106148 · Cited by 6,216

TOR signaling in growth and metabolism

Wullschleger, S., Loewith, R., & Hall, M. N. (2006) · Cell · doi:10.1016/j.cell.2006.01.016 · Cited by 5,787

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy.

Sandri, M., Sandri, C., Gilbert, A., Skurk, C., Calabria, E., Picard, A., Walsh, K., Schiaffino, S., Lecker, S. H., & Goldberg, A. L. (2004) · Cell · doi:10.1016/s0092-8674(04)00400-3 · Cited by 3,012

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

Alessi, D. R., James, S. R., Downes, C. P., Holmes, A. B., Gaffney, P. R. J., Reese, C. B., & Cohen, P. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00122-9 · Cited by 2,874

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Bodine, S. C., Stitt, T. N., Gonzalez, M., Kline, W. O., Stover, G. L., Bauerlein, R., Zlotchenko, E., Scrimgeour, A., Lawrence, J. C., Glass, D. J., et al. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-1014 · Cited by 2,752

Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Sarbassov, D. D., Ali, S. M., Kim, D.-H., Guertin, D. A., Latek, R. R., Erdjument-Bromage, H., Tempst, P., & Sabatini, D. M. (2004) · Current Biology · doi:10.1016/j.cub.2004.06.054 · Cited by 2,665

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

Lin, J., Wu, H., Tarr, P. T., Zhang, C.-Y., Wu, Z., Boss, O., Michael, L. F., Puigserver, P., Isotani, E., Olson, E. N., et al. (2002) · Nature · doi:10.1038/nature00904 · Cited by 2,546

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Jacinto, E., Loewith, R., Schmidt, A., Lin, S., Rüegg, M. A., Hall, A., & Hall, M. N. (2004) · Nature Cell Biology · doi:10.1038/ncb1183 · Cited by 2,097

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

Heitman, J., Movva, N. R., & Hall, M. N. (1991) · Science · doi:10.1126/science.1715094 · Cited by 2,010

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.

Stitt, T. N., Drujan, D., Clarke, B. A., Panaro, F., Timofeyva, Y., Kline, W. O., Gonzalez, M., Yancopoulos, G. D., & Glass, D. J. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00211-4 · Cited by 1,964

Therapeutic targeting of GDF11 in muscle atrophy: Insights and strategies

Wang, C., Liu, X., Hu, X., Wu, T., & Duan, R. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135321 · Cited by 6

Rapamycin administration causes a decrease in muscle contractile function and systemic glucose intolerance concomitant with reduced skeletal muscle Rictor, the mTORC2 component, expression independent of energy intake in young rats

Ato, S., Oya, C., & Ogasawara, R. (2024) · PLoS ONE · doi:10.1371/journal.pone.0312859 · Cited by 6

mTORC1 in the Control of Myogenesis and Adult Skeletal Muscle Mass

Wallace, M. A., Hughes, D. C., & Baar, K. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802733-2.00025-6 · Cited by 9

Phosphorylation of AMPKα at Ser485/491 Is Dependent on Muscle Contraction and Not Muscle-Specific IGF-I Overexpression

Chou, C., & Barton, E. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241511950 · Cited by 6

TORC1 mediated regulation of mitochondrial integrity and calcium ion homeostasis by Wat1/mLst8 in S. pombe

Anjum, S., Srivastava, S., Panigrahi, L., Ansari, U. A., Trivedi, A. K., & Ahmed, S. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.126907 · Cited by 6

Alterations in molecular muscle mass regulators after 8 days immobilizing Special Forces mission

Jespersen, J. G., Mikkelsen, U. R., Nedergaard, A., Thorlund, J. B., Schjerling, P., Suetta, C., Christensen, P. A., & Aagaard, P. (2014) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.12170 · Cited by 6

mTOR as a Marker of Exercise and Fatigue in Octopus vulgaris Arm

Maiole, F., Giachero, S., Fossati, S. M., Rocchi, A., & Zullo, L. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01161 · Cited by 7

mTOR Ser1261 is an AMPK ‐dependent phosphosite in mouse and human skeletal muscle not required for mTORC2 activity

Li, J., Madsen, A. B., Knudsen, J. R., Henríquez‐Olguín, C., Persson, K. W., Li, Z., Raun, S. H., Li, T., Kiens, B., Wojtaszewski, J. F. P., et al. (2025) · The FASEB Journal · doi:10.1096/fj.202402064r · Cited by 6

Alterations in Skeletal Muscle Insulin Signaling DNA Methylation: A Pilot Randomized Controlled Trial of Olanzapine in Healthy Volunteers

Burghardt, K., Burghardt, P. R., Howlett, B. H., Dass, S. E., Zahn, B., Imam, A., Mallisho, A., Msallaty, Z., Seyoum, B., & Yi, Z.-P. (2024) · Biomedicines · doi:10.3390/biomedicines12051057 · Cited by 4

Role of Mammalian Target of Rapamycin (mTOR) in Muscle Growth

Panzhinskiy, E., Culver, B. W., Ren, J. T., Bagchi, D., & Nair, S. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-396454-0.00022-9 · Cited by 5

Effects of a traditional Chinese medicine formula and its extraction on muscle fiber characteristics in finishing pigs, porcine cell proliferation and isoforms of myosin heavy chain gene expression in myocytes

Yu, Q. P., Feng, D. Y., He, X. J., Wu, F., Xia, M. H., Dong, T., Liu, Y. H., Tan, H. Z., Zou, S. G., Zheng, T., et al. (2017) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.16.0872 · Cited by 5

Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes

Kretschmar, C., Peña‐Oyarzún, D., Hernando, C., Hernández, N., Molina‐Berríos, A., Hernández‐Cáceres, M. P., Lavandero, S., Budini, M., Morselli, E., Parra, V., et al. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00280 · Cited by 5

The mTOR Signaling Pathway and Regulation of Pancreatic Function

Williams, M. D. S. A. J. A. (2017) · doi:10.3998/panc.2017.08 · Cited by 4

The Role of mTOR in Amyotrophic Lateral Sclerosis

Nogueira-Machado, J. A., Rocha-Silva, F., & Gomes, N. A. (2025) · Biomedicines · doi:10.3390/biomedicines13040952 · Cited by 4

Autophagy as a therapeutic linchpin in metabolic diseases and obesity-associated diabetes

Vakili, O., Klionsky, D. J., Reiter, R. J., Ren, J., Deshpande, A., Ahn, K. S., Cho, W., Hushmandi, K., & Kumar, A. P. (2026) · Autophagy · doi:10.1080/15548627.2026.2636096 · Cited by 7

Physiological Regulation of Skeletal Muscle Mass

Pérez‐Schindler, J., & Handschin, C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-810422-4.00011-7 · Cited by 4

Long-term administration of sirolimus does not affect the physical development of children with tuberous sclerosis complex

Chen, J., He, W., Wang, Y., Zhang, M., Lu, Q., Wang, Q., Luo, X., Wang, B., & Zou, L. (2022) · Child s Nervous System · doi:10.1007/s00381-022-05446-2 · Cited by 4

Molecular basis of muscle hypertrophy and atrophy: Potential therapy for muscular dystrophy

Ito, N., Miyagoe‐Suzuki, Y., & Takeda, S. (2013) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.2.179 · Cited by 4

8-Weeks of β-GPA Treatment Reduces Body Mass While Positively Altering Translation Initiation in Obese Skeletal Muscle

Drake, J. C., Benninger, L. A., & Williamson, D. L. (2011) · Journal of Obesity & Weight loss Therapy · doi:10.4172/2165-7904.1000101 · Cited by 4

Nano branched-chain amino acids enhance the effect of uphill (concentric) and downhill (eccentric) treadmill exercise on muscle gene expression of Akt and mTOR on aged rats

Sadri, S., Sharifi, G., & Dehkordi, K. J. (2021) · Sport Sciences for Health · doi:10.1007/s11332-021-00828-6 · Cited by 4

Evaluation of mTOR function by a gain-of-function approach

Ohne, Y., Takahara, T., & Maeda, T. (2009) · Cell Cycle · doi:10.4161/cc.8.4.7660 · Cited by 4

Raptor Swoops in on Metabolism

Shaw, R. J. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.10.007 · Cited by 4

Full-length PGC-1α salvages the phenotype of a mouse model of human neuropathy through mitochondrial proliferation

Ròna-Vörös, K., Eschbach, J., Vernay, A., Wiesner, D., Schwalenstöcker, B., Geniquet, P., de Camaret, B. M., Echaniz‐Laguna, A., Loeffler, J., Ludolph, A. C., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt359 · Cited by 4

Longevity as a Complex Genetic Trait

Sutphin, G. L., & Korstanje, R. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-411596-5.00001-0 · Cited by 4

Reduced mTORC1 ‐signaling in retinal ganglion cells leads to vascular retinopathy

Jones, I., Hägglund, A., & Carlsson, L. (2021) · Developmental Dynamics · doi:10.1002/dvdy.389 · Cited by 4

Systematic Exploration of Molecular Mechanisms and Natural Herbal Therapeutic Strategies for Cancer Cachexia

Han, P., Zhou, X., Dong, G., Ma, L., Han, X., Liu, D., Zheng, J., & Zhang, J. (2025) · Cancers · doi:10.3390/cancers18010104 · Cited by 2

Metabolomic and Lipidomic Signature of Skeletal Muscle with Constitutively Active Mechanistic Target of Rapamycin Complex 1

Maroto, R., Graber, T. G., Romsdahl, T. B., Kudlicki, A. S., Russell, W. K., & Rasmussen, B. B. (2023) · Journal of Nutrition · doi:10.1016/j.tjnut.2023.10.016 · Cited by 4

The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation

Yao, Y., Hong, S., Yoshida, S., Swaroop, V., Curtin, B., & Inoki, K. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.115101 · Cited by 3

Role of Mammalian Target of Rapamycin in Muscle Growth

Panzhinskiy, E., Culver, B. W., Ren, J. T., Bagchi, D., & Nair, S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813922-6.00022-9 · Cited by 3

Insulin and Growth Factor Signaling Pathways

Kyriakis, J. M., & Avruch, J. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00004-6 · Cited by 3

AGC Kinases in mTOR Signaling

Jacinto, E. (2010) · The Enzymes · doi:10.1016/s1874-6047(10)27007-5 · Cited by 3

mTORC1 and mTORC2 in Energy Homeostasis

Cornu, M., & Hall, M. N. (2010) · The Enzymes · doi:10.1016/s1874-6047(10)28013-7 · Cited by 3

Translational and Post-translational Control of Leptin Production by Fat Cells

Kandror, K. V. (2015) · Springer eBooks · doi:10.1007/978-3-319-25124-0_10 · Cited by 3

Modeling and analysis of the signaling crosstalk of PI3K, AMPK and MAPK with Timed Hybrid Petri Nets approach

Bibi, Z., Ahmad, J., Paracha, R. Z., & Siddiqa, A. (2017) · International Conference on Computational Science and Its Applications · doi:10.1109/iccsa.2017.8000019 · Cited by 3

Skeletal Muscle mTORC1 Activation Increases Energy Expenditure and Reduces Longevity in MicePreprint

Stephenson, E. J., Redd, J. R., Snyder, D., Tran, Q. T., Lu, B., Peloquin, M., Mulcahy, M. C., Harvey, I. C., Fisher, K., Han, J. C., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/720540 · Cited by 4

Interplay between mTORC1 signaling and iron homeostasis in muscle atrophy

Jee, E., Ouf, W., Kim, J., & Kim, Y. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.10.257 · Cited by 2

Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity

Grahammer, F., Dumoulin, B., Gulieva, R. E., Wu, H., Xu, Y., Sulaimanov, N., Arnold, F., Sandner, L., Cordts, T., Todkar, A., et al. (2024) · Kidney International · doi:10.1016/j.kint.2024.08.021 · Cited by 2

Skeletal Muscle Homeostasis and Aging in Drosophila

Puppa, M., & Demontis, F. (2015) · Healthy ageing and longevity · doi:10.1007/978-3-319-18326-8_5 · Cited by 2

mTOR Signaling in Cortical Network Development

Lin, T. V., & Bordey, A. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-415804-7.00015-0 · Cited by 1

Getting to the finish line with mTORC1-targeted therapy

Henske, E. P. (2012) · Journal of Clinical Investigation · doi:10.1172/jci64227 · Cited by 2

Targeting tissue-specific metabolic signaling pathways in aging: the promise and limitations

Hu, F., & Liu, F. (2013) · Protein & Cell · doi:10.1007/s13238-013-3077-y · Cited by 2

IGF-1 Regulation of Skeletal Muscle Hypertrophy and Atrophy

Glass, D. J. (2009) · Research and perspectives in endocrine interactions · doi:10.1007/978-3-642-04302-4_7 · Cited by 2

mTOR in Metabolic and Endocrine Disorders

Swierczynska, M. M., & Hall, M. N. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802733-2.00008-6 · Cited by 2

Dietary protein governs the role of insulin signaling in the postprandial regulation of hepatic mTORC1

Kalafut, K. C., Cormerais, Y., Cissé, M. Y., Lapp, S. C., Inouye, K., Hotamışlıgil, G. S., & Manning, B. D. (2026) · Nature Communications · doi:10.1038/s41467-026-77216-6 · Cited by 2

Lactate metabolism–related differentially expressed genes reveal biological mechanisms underlying sarcopenia

Li, Y., & Xu, Z. (2025) · Scientific Reports · doi:10.1038/s41598-025-25525-z · Cited by 1

Endocrine Late Effects of Targeted and Immune-Based Therapies in Pediatric Oncology

Ferrari, V. D., Ranieri, A., Ruggi, A., Lanari, M., Melchionda, F., Prete, A., & Baronio, F. (2026) · Cells · doi:10.3390/cells15080676 · Cited by 2

Dysregulation of the ubiquitin–proteasome system in aging skeletal muscle

Song, G., Lee, B.-Y., & Baek, K. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119504 · Cited by 2

Organelle Stress and mTOR in Aging-Associated Inflammation

Pani, G. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397803-5.00014-9 · Cited by 1

Inhibitory Effect of the Glycerophosphate Moiety of Lipoteichoic Acid from Lactic Acid Bacteria on Dexamethasone-Induced Atrogin-1 Expression in C2C12 Myotubes

KATSUKI, R., Shiraishi, T., SAKATA, S., Hirota, T., Nakamura, Y., & Yokota, S. (2021) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.67.351 · Cited by 1

Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics.

Li, H., Cotton, J. L., & Guertin, D. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-430-8_21 · Cited by 1

Skeletal muscle atrophy

Pierre-Jerome, C. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13328-2.00008-8 · Cited by 1

Role of mTOR Signaling in Cardioprotection

Das, A., & Kukreja, R. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802733-2.00003-7 · Cited by 1

The PI3K-mTOR Pathway

Thomas, H. E., Veiga, S. R., Thomas, G., & Kozma, S. C. (2015) · Springer eBooks · doi:10.1007/978-2-8178-0492-7_2 · Cited by 1

mTOR Inhibitor Therapy for Tuberous Sclerosis Complex: Longitudinal Study of Muscle Mass Determined by Abdominal Cross-sectional Imaging with CT and MRI

Raab, C., Gilligan, L. A., Trout, A. T., Krueger, D. A., Franz, D. N., Zhang, B., & Towbin, A. J. (2020) · Radiology Imaging Cancer · doi:10.1148/rycan.2020190091 · Cited by 1

Role of Map4k4 in Skeletal Muscle Differentiation: A Dissertation

Wang, M. (2013) · eScholarship@UMassChan · doi:10.13028/m2cw28 · Cited by 1

Insulin Resistance in Obesity

Qi, Y., Guo, X., & Guo, S. (2015) · Springer eBooks · doi:10.1007/978-3-319-12125-3_28-1 · Cited by 1

Understanding the mechanisms of dietary restriction to extend healthy lifespan in Drosophila melanogaster.

Emran, S. (2015) · UCL Discovery (University College London) · Cited by 1

The mTOR Signaling Pathway and Regulation of Pancreatic Function (Version 2.0

Williams, M. D. S. A. J. A. (2021) · doi:10.3998/panc.2021.15 · Cited by 1

Leucine and exercise improve skeletal muscle function in the mdx mouse

Voelker, K. A. (2010) · VTechWorks (Virginia Tech)

Endotoxin induced muscle wasting in avian and murine skeletal muscle

Tarabees, R. (2011) · Nottingham ePrints (University of Nottingham)

mTORC2 controls neuron size and Purkinje cell morphology independent of mTORC1

Thomanetz, V. (2012) · edoc (University of Basel) · doi:10.5451/unibas-005976915

mTOR Pathway is Up-regulated by Both Acute Endurance Exercise and Chronic Muscle Contraction in Rat Skeletal Muscle

Edgett, B. A. (2012) · QSpace (Queen's University Library)

Inflammation: Where Does It All Go Wrong? mTor Signaling in Skeletal Muscle During Sepsis and

Puppa, M., Gao, S., Narsale, A. A., Carson, J. A., Ramsey, M. W., Stone, M. H., Stuart, C. A., Howell, M. E. A., Cartwright, B. M., McCurry, M. P., et al. (2015)

Influence of Insulin Resistance on Contractile Activity-Induced Anabolic Response of Skeletal Muscle

Nilsson, M. I. (2011) · OakTrust (Texas A&M University Libraries)

Obesity dyslipidemia: the effect of central nervous system neuropeptide Y on hepatic lipoprotein metabolism

Rojas, J. M. (2013)

mTORC2

Treins, C., & Downward, J. (2010) · The Enzymes · doi:10.1016/s1874-6047(10)28005-8

Big vs powerful : molecular signalling responses to hypertrophic and power resistance exercise modalities

Loh, R. (2015)

Ein hoher Mitochondriengehalt korreliert mit der Progression des Prostatakarzinoms

Jedrzejewska, K. (2016)

Function of mTOR complex 1 and 2 in Skeletal Muscle

Fakultät, P.-N. (2009)

Mtor-Fanconi Anemia DNA Damage Repair Pathway in Cancer Keywords: mTOR; Fanconi anemia pathway; FANCD2; DNA repair;

Guo, F. (2014)

Activation of mTORC1 Improves Cone Cell Metabolism and Extends Vision in Retinitis Pigmentosa Mice: A Dissertation

Venkatesh, A. (2016) · eScholarship@UMassChan · doi:10.13028/m2nc7g

Unraveling Mechanisms of Insulin Resistance in Type 2 Diabetes in Human Adipocytes : Role of extracellular signal regulated kinase 1/2 (ERK1/2) and forkhead box protein 01 (FOX01)

Rajan, M. R. (2016) · Linköping University medical dissertations · doi:10.3384/doss.diva-131421

Vascular Aging: from Smooth Muscle Cell Differentiation to Polyploidization

Zhan, S. (2016) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/28633

The regulation of cancer cachexia and colorectal carcinogenesis by myostatin

Wijesoma, I. W. (2017) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/72527

mTORC1 activates PASK-Wdr5 signaling to epigenetically connect the nutrient status with myogenesisPreprint

Kikani, C. K., Wu, X., Fogarty, S., Kang, S. A. W., Dephoure, N., Gygi, S. P., Sabatini, D. M., & Rutter, J. P. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/232173

Molecular Regulation of Muscle Protein Synthesis at Rest and Following Endurance Exercise

Sawan, S. A. (2017) · TSpace (University of Toronto)

The role of mTORC2 in mammary morphogenesis and HER2-mediated tumorigenesis

Morrison, M. M. (2015)

Burn-Induced Muscle Wasting: Changes in Muscle Progenitor Cells

Yousuf, Y. (2018) · TSpace (University of Toronto)

Molecular Mechanisms of Postmeal Regulation of Muscle Anabolism

Bacquer, O. L. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-810422-4.00003-8

Efeitos de diferentes glicocorticoides sobre as vias moleculares de regulação do trofismo muscular em ratos e o efeito do EPA/DHA na atrofia muscular induzida pela dexametasona

Fappi, A. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2018.tde-14082018-103310

mTORC1 signaling is not essential for the maintenance of muscle mass and function in adult sedentary micePreprint

Ham, A. S., Chojnowska, K., Tintignac, L. A. J., Lin, S., Schmidt, A., Ham, D. J., Sinnreich, M., & Rüegg, M. A. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/738294

Deciphering the crosstalk of the mTORC1 and MAPK networks in cancer

Navas, P. R. (2020) · doi:10.33612/diss.123822961

Mammalian target of rapamycin complexes

Querfurth, H. W., & Lee, H. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815868-5.00021-9

Roles of autophagy & mitophagy in the regulation of skeletal muscle function

Leduc‐Gaudet, J. (2021) · eScholarship@McGill (McGill) · doi:10.82308/1594

Влияние ограничения питания на старение: исправление проблем с «сенсорами питания» у постмитотических клеток?

Васильевна, М. Г., Шиловский, Г. А., & Khokhlov, A. N. (2021) · Biochemistry (Moscow) · doi:10.31857/s0320972521100092

La gestion prévisionnelle des emplois et des compétences: un défi social, économique et juridique. Les sanctions de la GPEC.

Neau-Leduc, C. (2007) · HAL

The Effect of Cancer Cachexia Progression on the Feeding Regulation of Skeletal Muscle Protein Turnover

Counts, B. R. (2021) · doi:10.21007/etd.cghs.2021.0559

Insulin Resistance in Obesity

Qi, Y., Guo, X., & Guo, S. (2015) · Springer eBooks · doi:10.1007/978-3-319-12125-3_28-2

Longevity as a complex genetic trait

Sutphin, G. L., & Korstanje, R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-815962-0.00001-9

mTORC1 activity is essential for disease progression in chronic lymphocytic leukemiaPreprint

Malik, N., Hay, J., Dunn, K. M., Nakagawa, R., Sansom, O. J., & Michie, A. M. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.19.488778

Long term AMPK activation limits obesity induced muscle atrophy

Drake, J. C. (2010) · doi:10.33915/etd.2992

References

(2013) · Elsevier eBooks · doi:10.1016/b978-0-12-388425-1.00023-3

Faculty Opinions recommendation of The muscle fiber type-fiber size paradox: hypertrophy or oxidative metabolism?

Lynch, G. S. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.726397925.793563870

Molecular mechanism of sarcopenia

井上愛子, 憲武, 成., 大貴, 五., & 葛谷, 雅. (2018) · Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics · doi:10.3143/geriatrics.55.13

Molecular Architecture of Androgen Receptor Pathways Amplifying Glucagon-Like Peptide-1 Insulinotropic Action in Male Pancreatic β-CellsPreprint

Xu, W., Qadir, F., Nasteska, D., de Sa, P. M., Gorvin, C. M., Blandino-Rosano, M., Evans, C. R., Ashford, F. B., Bitsi, S., Fan, J., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4114953

Loss of PTPMT1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout micePreprint

Zheng, H., Li, Q., Li, S., Li, Z., Brotto, M. A. P., Weiss, D., Prosdocimo, D. A., Xu, C., Reddy, A., Puchowicz, M., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.09.523031

Wat1/mLst8, a TOR complex protein regulates mitochondrial integrity and calcium ion homeostasis in fission yeast S. pombePreprint

Anjum, S., Srivastava, S., Panigrahi, L., Ansari, U. A., Trivedi, A. K., & Ahmed, S. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.27.534337

Data from mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer

Driscoll, D. R., Karim, S. A., Sano, M., Gay, D. M., Jacob, W., Yu, J. Q., Mizukami, Y., Gopinathan, A., Jodrell, D. I., Evans, T. R. J., et al. (2023) · doi:10.1158/0008-5472.c.6508418.v1

Reviewer #1 (Public Review): Loss of PTPMT1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure

Zheng, H., Li, Q., Li, S., et al. (2023) · eLife · doi:10.7554/elife.86944.1.sa1

Loss of PTPMT1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failurePreprint

Zheng, H., Li, Q., Li, S., Li, Z., Brotto, M. A. P., Weiss, D., Prosdocimo, D. A., Xu, C., Reddy, A., Puchowicz, M., et al. (2023) · eLife · doi:10.7554/elife.86944.1

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

Risson, V., Mazelin, L., Roceri, M., Sanchez, H., Moncollin, V., Corneloup, C., Richard-Bulteau, H., Vignaud, A., Baas, D., Defour, A., et al. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200903131 · Cited by 381

The role of mTOR complex 1 in skeletal muscle

Romanino, K. (2012) · edoc (University of Basel) · doi:10.5451/unibas-006041355

Function of mTOR complex 1 and 2 in skeletal muscle

Bentzinger, C. F. (2009) · edoc (University of Basel) · doi:10.5451/unibas-004780718 · Cited by 1

Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function

Romanino, K., Mazelin, L., Albert, V., Conjard‐Duplany, A., Lin, S., Bentzinger, C. F., Handschin, C., Puigserver, P., Zorzato, F., Schaeffer, L., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1111448109 · Cited by 44

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy

Bentzinger, C. F., Lin, S., Romanino, K., Castets, P., Guridi, M., Summermatter, S., Handschin, C., Tintignac, L. A., Hall, M. N., & Rüegg, M. A. (2013) · Skeletal Muscle · doi:10.1186/2044-5040-3-6 · Cited by 153