Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
Palsson-McDermott, Eva M., Curtis, Anne M., Goel, Gautam, Lauterbach, Mario A.R., Sheedy, Frederick J., Gleeson, Laura E., van den Bosch, Mirjam W.M., Quinn, Susan R., Domingo-Fernandez, Raquel, Johnston, Daniel G.W., Jiang, Jian-kang, Israelsen, William J., Keane, Joseph, Thomas, Craig, Clish, Clary, Vander Heiden, Matthew, Xavier, Ramnik J., O’Neill, Luke A.J.·2015·Cell Metabolism
Cited by (1,001)
Items 201–300 of 1,001
- PD-L1 blockade liberates intrinsic antitumourigenic properties of glycolytic macrophages in hepatocellular carcinomaLi-Gong Lu, Zhi-Ling Zhou, Xu-Yan Wang, Boyuan Liu, Jin-Zhi Lu, Shuai Liu, Guang-Bo Zhang, Mei-Xiao Zhan, Yun Chen · 2022 · Gut
- Glucose metabolism of TAMs in tumor chemoresistance and metastasisJuan Liu, Xuetao Cao · 2023 · Trends in Cell Biology
- The Dynamic Inflammatory Tissue Microenvironment: Signality and Disease Therapy by BiomaterialsRani Mata, Yuejun Yao, Wangbei Cao, Jie Ding, Tong Zhou, Zihe Zhai, Changyou Gao · 2021 · Research
- Role of Metabolic Reprogramming in Pulmonary Innate Immunity and Its Impact on Lung DiseasesCharalambos Michaeloudes, Pankaj Kumar Bhavsar, Sharon E. Mumby, Bingling Xu, Christopher Hui, Kian Fan Chung, Ian Michael Adcock · 2019 · Journal of Innate Immunity
- A novel PINK1- and PARK2-dependent protective neuroimmune pathway in lethal sepsisRui Kang, Ling Zeng, Yangchun Xie, Zhengwen Yan, Bo Zhou, Lizhi Cao, Daniel J. Klionsky, Kevin J. Tracey, Jianhua Li, Haichao Wang et al. · 2016 · Autophagy
- Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic ReprogrammingAngelo D’Alessandro, Karim Christian El Kasmi, Lydie Plecitá‐Hlavatá, Petr Ježek, Min Li, Hui Zhang, Sachin A. Gupte, Kurt R. Stenmark · 2017 · Antioxidants and Redox Signaling
- The role of metabolic reprogramming in tubular epithelial cells during the progression of acute kidney injuryZhenzhen Li, Shan Lu, Xiaobing Li · 2021 · Cellular and Molecular Life Sciences
- Succinate/NLRP3 Inflammasome Induces Synovial Fibroblast Activation: Therapeutical Effects of Clematichinenoside AR on ArthritisYi Li, Jia‐Yi Zheng, Jianqun Liu, Jie Yang, Yang Liu, Chen Wang, Xiaonan Ma, Baolin Liu, Gui-Zhong Xin, Lifang Liu · 2016 · Frontiers in Immunology
- Biochemistry of proinflammatory macrophage activationYannic Nonnenmacher, Karsten Hiller · 2018 · Cellular and Molecular Life Sciences
- Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategiesDivya Tiwari, Adrian R. Martineau · 2022 · Seminars in Immunology
- PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinomaJiao Feng, Liwei Wu, Jie Ji, Kan Chen, Qiang Yu, Jie Zhang, Jiaojiao Chen, Yuqing Mao, Fan Wang, Weiqi Dai et al. · 2019 · Journal of Experimental & Clinical Cancer Research
- Immunometabolism in TuberculosisLanbo Shi, Eliseo A. Eugenín, Selvakumar Subbian · 2016 · Frontiers in Immunology
- Glycine Exhibits Neuroprotective Effects in Ischemic Stroke in Rats through the Inhibition of M1 Microglial Polarization via the NF-κB p65/Hif-1α Signaling PathwayRui Liu, Xinyu Liao, Meng‐Xian Pan, Jun‐Chun Tang, Songfeng Chen, Ya Zhang, Peixin Lu, Long Jason Lu, Yingying Zou, Xingping Qin et al. · 2019 · The Journal of Immunology
- Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunitySamuel Martins Gonçalves, Cláudio Duarte‐Oliveira, Cláudia F. Campos, Vishukumar Aimanianda, Rob ter Horst, Luis Leite, Toine Mercier, Paulo N. G. Pereira, Miguel Fernández-García, Daniela Antunes et al. · 2020 · Nature Communications
- A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19Oliver J. McElvaney, Brian D. Hobbs, Dandi Qiao, Oisín F. McElvaney, Matthew R. Moll, Natalie L. McEvoy, Jennifer Clarke, Eoin O’Connor, Seán Walsh, Michael H. Cho et al. · 2020 · EBioMedicine
- Aerobic glycolysis is a metabolic requirement to maintain the M2-like polarization of tumor-associated macrophagesNatália Mesquita de Brito, Julia Duncan Moretti, Hayandra Cunha da-Costa, Roberta Ferreira Gomes Saldanha-Gama, Heitor A. Paula-Neto, Gabriel G. Dorighello, Rafael Loureiro Simões, Christina Barja‐Fidalgo · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effectPiao Luo, Qian Zhang, Tianyu Zhong, Jia-Yun Chen, Junzhe Zhang, Ya Tian, Liuhai Zheng, Fan Yang, Lingyun Dai, Chang Zou et al. · 2022 · Military Medical Research
- Glycolysis drives STING signaling to facilitate dendritic cell antitumor functionZhilin Hu, Xiaoyan Yu, Rui Ding, Ben Liu, Chuanjia Gu, Xiuwu Pan, Qiaoqiao Han, Yuerong Zhang, Jie Wan, Xingang Cui et al. · 2023 · Journal of Clinical Investigation
- TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsisThierry Gauthier, Chen Yao, Tyrone Dowdy, Wenwen Jin, Yun-Ji Lim, Liliana Catherine Patiño, Na Liu, Shannon I. Ohlemacher, Andrew Bynum, Rida Kazmi et al. · 2023 · Science Signaling
- Macrophage-driven cardiac inflammation and healing: insights from homeostasis and myocardial infarctionWenjie Zuo, Renhua Sun, Zhenjun Ji, Genshan Ma · 2023 · Cellular & Molecular Biology Letters
- Lactate and lactylation in cardiovascular diseases: current progress and future perspectivesWengen Zhu, Siyu Guo, Junyi Sun, Yudan Zhao, Chen Liu · 2024 · Metabolism
- Covalent inhibition of pyruvate kinase M2 reprograms metabolic and inflammatory pathways in hepatic macrophages against non-alcoholic fatty liver diseaseFan, Ni, Zhang, Xiuying, Zhao, Wei, Zhao, Jia, Luo, Dan, Sun, Yilu, Li, Ding, Zhao, Chenliang, Wang, Yu, Zhang, Hongjie et al. · 2022 · International Journal of Biological Sciences
- Vitamin D endocrinology on the cross-road between immunity and metabolismAn-Sofie Vanherwegen, Conny A. Gysemans, Chantal Mathieu · 2017 · Molecular and Cellular Endocrinology
- PKM2, a potential target for regulating cancerYuhuan Li, Xiaofeng Li, Jiatao Liu, Hua Wang, Lulu Fan, Jun Li, Guoping Sun · 2018 · Gene
- The PKM2 activator TEPP‐46 suppresses kidney fibrosis via inhibition of the EMT program and aberrant glycolysis associated with suppression of HIF‐1α accumulationHaijie Liu, Yuta Takagaki, Asako Kumagai, Keizo Kanasaki, Daisuke Koya · 2020 · Journal of Diabetes Investigation
- Lactate and lactylation in macrophage metabolic reprogramming: current progress and outstanding issuesBangjun Xu, Yi Liu, Ning Li, Qing Geng · 2024 · Frontiers in Immunology
- Cancer-associated adipocytes as immunomodulators in cancerWu, Qi, Li, Bei, Li, Juanjuan, Sun, Si, Yuan, Jingping, Sun, Shengrong · 2021 · Biomarker Research
- Metabolic Inflammation-Differential Modulation by Dietary ConstituentsClaire L. Lyons, Elaine B. Kennedy, Helen M. Roche · 2016 · Nutrients
- The PD-1/PD-L1 axis contributes to immune metabolic dysfunctions of monocytes in chronic lymphocytic leukemiaMirjeta Qorraj, Heiko Bruns, Martin Böttcher, Luise Weigand, Domenica Saul, Andréas Mackensen, Regina Jitschin, Dimitrios Mougiakakos · 2016 · Leukemia
- MiR-186 inhibited aerobic glycolysis in gastric cancer via HIF-1α regulationL Liu, Y Wang, Rubing Bai, Keda Yang, Zhong Tian · 2016 · Oncogenesis
- Targeting Metabolism as a Novel Therapeutic Approach to Autoimmunity, Inflammation, and TransplantationIan A. Bettencourt, Jonathan D. Powell · 2017 · The Journal of Immunology
- Origins and diversity of macrophages in health and diseaseGopalkrishna Sreejit, Andrew J. Fleetwood, Andrew James Murphy, Prabhakara R. Nagareddy · 2020 · Clinical & Translational Immunology
- A past and present overview of macrophage metabolism and functional outcomesRui Curi, Renata de Siqueira Mendes, Luiz Aurélio de Campos Crispin, Giuseppe Danilo Norata, Sandra Coccuzzo Sampaio, Philip Newsholme · 2017 · Clinical Science
- Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertensionKurt R. Stenmark, Rubin M. Tuder, Karim Christian El Kasmi · 2015 · Journal of Applied Physiology
- Metabolic characterization and RNA profiling reveal glycolytic dependence of profibrotic phenotype of alveolar macrophages in lung fibrosisNa Xie, Huachun Cui, Jing Ge, Sami Banerjee, Sijia Guo, Shubham Dubey, Edward H Abraham, Rui-Ming Liu, Gang Liu · 2017 · American Journal of Physiology-Lung Cellular and Molecular Physiology
- Regulations of Glycolytic Activities on Macrophages Functions in Tumor and Infectious InflammationQing Yu, Yufei Wang, Dong Lin, Ying He, Ruichen Liu, Qiuli Yang, Yejin Cao, Yuexin Wang, Anna Jia, Yujing Bi et al. · 2020 · Frontiers in Cellular and Infection Microbiology
- Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanismMengwen Zhang, Xingyi Pan, Kenji Fujiwara, Noelle R. Jurcak, Stephen T. Muth, Jiaojiao Zhou, Qian Xiao, Anqi Li, Xu Che, Zihai Li et al. · 2021 · Signal Transduction and Targeted Therapy
- Commitment to Aerobic Glycolysis Sustains Immunosuppression of Human Mesenchymal Stem CellsYijun Liu, Xuegang Yuan, Nathalie Munoz Munoz, Timothy M. Logan, Teng Ma · 2018 · Stem Cells Translational Medicine
- Is Retinal Metabolic Dysfunction at the Center of the Pathogenesis of Age-related Macular Degeneration?Thierry Léveillard, Nancy J. Philp, Florian Sennlaub · 2019 · International Journal of Molecular Sciences
- Protein kinase function of pyruvate kinase M2 and cancerXun Chen, Shangwu Chen, Dongsheng Yu · 2020 · Cancer Cell International
- Hypoxia/HIF Modulates Immune ResponsesYuling Chen, Timo Gaber · 2021 · Biomedicines
- Mitochondrial metabolism mediated macrophage polarization in chronic lung diseasesTing Dong, Xinyi Chen, Haochuan Xu, Yaxin Song, Huirui Wang, Yinghui Gao, Jingcheng Wang, Ruiqing Du, Hongxiang Lou, Ting Dong · 2022 · Pharmacology & Therapeutics
- Macrophage Polarization Mediated by Mitochondrial Dysfunction Induces Adipose Tissue Inflammation in ObesityLong Xu, Xiaoyu Yan, Yuanxin Zhao, Jian Song, Buhan Liu, Sihang Yu, Jiaying Fu, Yanan Liu, Jing Su · 2022 · International Journal of Molecular Sciences
- PKM2 is involved in neuropathic pain by regulating ERK and STAT3 activation in rat spinal cordBinbin Wang, Siyuan John Liu, Bingbing Fan, Xingguo Xu, Yonglin Chen, Rongxiang Lu, Zhongling Xu, Xiaojuan Liu · 2018 · The Journal of Headache and Pain
- Regulation of Immune Cell Functions by Metabolic ReprogrammingJaehong Kim · 2018 · Journal of Immunology Research
- Trained immunity is induced in humans after immunization with an adenoviral vector COVID-19 vaccineDearbhla M Murphy, Donal J Cox, Sarah A. Connolly, Eamon P. Breen, Aenea AI Brugman, James Joseph Phelan, Joseph Keane, Sharee A. Basdeo · 2022 · Journal of Clinical Investigation
- Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2Kaustav Das Gupta, Melanie R. Shakespear, James E. B. Curson, Ambika M. V. Murthy, Abishek Iyer, Mark P. Hodson, Divya Ramnath, Vikas A. Tillu, Jessica B. von Pein, Robert C. Reid et al. · 2020 · Cell Reports
- Enhanced glycolysis, regulated by HIF-1α via MCT-4, promotes inflammation in arsenite-induced carcinogenesisFei Luo, Zhonglan Zou, Xinlu Liu, Min Ling, Qingling Wang, Qi Wang, Lu Lu, Le Shi, Yonglian Liu, Qizhan Liu et al. · 2017 · Carcinogenesis
- miR675 upregulates long noncoding RNA H19 through activating EGR1 in human liver cancerHaiyan Li, Jiao Li, Song Jia, Mengying Wu, Jiahui An, Qidi Zheng, Wei Zhang, Dongdong Lu · 2015 · Oncotarget
- The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2 ProductionZbigniew Zasłona, Eva M. Pålsson‐McDermott, Deepthi Menon, Moritz Haneklaus, Ewelina Flis, Hannah Prendeville, Sarah E. Corcoran, Marc L. Peters-Golden, Luke A.J. O'Neill · 2017 · The Journal of Immunology
- Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunityRyu Watanabe, Tsuyoshi Shirai, Hong Namkoong, Hui Zhang, Gerald J. Berry, Barbara B. Wallis, Benedikt Schaefgen, David Glenn Harrison, Jennifer A. Tremmel, John C. Giacomini et al. · 2017 · Journal of Clinical Investigation
- Metabolic features of macrophages in inflammatory diseases and cancerYi Rang Na, Sungmo Je, Seung Hyeok Seok · 2017 · Cancer Letters
- The NLRP3 inflammasome: Role in metabolic disorders and regulation by metabolic pathwaysDanlu Jiang, Sheng Chen, Ruyu Sun, Xue Zhang, Di Wang · 2018 · Cancer Letters
- Endothelial pyruvate kinase M2 maintains vascular integrityBoa Kim, Cholsoon Jang, Harita Dharaneeswaran, Jian Li, Mohit Bhide, Steven Hoseong Yang, Kristina Li, Zoltan Pierre Arany · 2018 · Journal of Clinical Investigation
- Specific Inhibition of the NLRP3 Inflammasome as an Antiinflammatory Strategy in Cystic FibrosisOliver J. McElvaney, Zbigniew Zasłona, Katrin Anne Becker-Flegler, Eva M. Pålsson‐McDermott, Fiona Boland, Cedric Gunaratnam, Erich Gulbins, Luke A.J. O'Neill, Emer P. Reeves, Noel Gerard McElvaney · 2019 · American Journal of Respiratory and Critical Care Medicine
- Cinnamaldehyde suppresses NLRP3 derived IL-1β via activating succinate/HIF-1 in rheumatoid arthritis rats.Panwang Liu, Jie Wang, Wen Wen, Ting Pan, Huan Chen, Ying Fu, Fu-Shun Wang, Jason H. Huang, Shi-Jun Xu · 2020 · International Immunopharmacology
- Metabolic reprograming of tumor-associated macrophagesAbhishek Puthenveetil, Shweta Dubey · 2020 · Annals of Translational Medicine
- The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAsDexter L. Puckett, Mohammed Ibrahim Alquraishi, Winyoo Chowanadisai, Ahmed Bettaieb · 2021 · International Journal of Molecular Sciences
- The Regulatory Role of α‐Ketoglutarate Metabolism in MacrophagesShaojuan Liu, Jie Yang, Zhenfang Wu · 2021 · Mediators of Inflammation
- Epigenetics and Immunometabolism in Diabetes and AgingTomasz Jan Guzik, Francesco Cosentino · 2017 · Antioxidants and Redox Signaling
- Metabolic regulation of macrophages in tissuesJan Van den Bossche, Doina L. Saraber · 2018 · Cellular Immunology
- Immunometabolism of Macrophages in Bacterial InfectionsGaël Galli, Maya Saleh · 2021 · Frontiers in Cellular and Infection Microbiology
- Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responsesMimmi L. E. Lundahl, Morgane Mitermite, Dylan G. Ryan, Sarah Case, Niamh C. Williams, Ming Hui Yang, Roisin I. Lynch, Eimear Lagan, Filipa Lebre, Aoife L. Gorman et al. · 2022 · eLife
- The injured sciatic nerve atlas (iSNAT), insights into the cellular and molecular basis of neural tissue degeneration and regenerationXiaofeng Zhao, Lucas D. Huffman, Hannah Hafner, Mitre Athaiya, Matthew C. Finneran, Ashley L. Kalinski, Rafi Kohen, Corey G. K. Flynn, Ryan Passino, Craig N. Johnson et al. · 2022 · eLife
- The role of immunometabolism in macrophage polarization and its impact on acute lung injury/acute respiratory distress syndromeLian Wang, Dongguang Wang, Tianli Zhang, Yao Ma, Xiang Tong, Hong Fan · 2023 · Frontiers in Immunology
- Lipopolysaccharide promotes Drp1‐dependent mitochondrial fission and associated inflammatory responses in macrophagesRonan Kapétanovic, Syeda Farhana Afroz, Divya Ramnath, Grace M. E. P. Lawrence, Takashi Okada, James E. B. Curson, Jost de Bruin, David P. Fairlie, Kate Schroder, Justin C. St. John et al. · 2020 · Immunology and Cell Biology
- Mitohormesis reprogrammes macrophage metabolism to enforce toleranceGreg A. Timblin, Kevin M. Tharp, Breanna Ford, Janet Winchester, Jerome Wang, Stella Zhu, Rida I. Khan, Shannon K. Louie, Anthony T. Iavarone, Johanna ten Hoeve et al. · 2021 · Nature Metabolism
- Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic NephropathyDaniel Gordin, Hetal Shah, Takanori Shinjo, Ronald St-Louis, Weier Qi, Kyoungmin Park, Samantha Megan Paniagua, DAVID M. POBER, I‐Hsien Wu, Vanessa Bahnam et al. · 2019 · Diabetes Care
- PKM2 Drives Hepatocellular Carcinoma Progression by Inducing Immunosuppressive MicroenvironmentTian‐En Li, Shun Wang, Xiaotian Shen, Ze Zhang, Mo Chen, Hao Wang, Ying Zhu, Da Xu, Beiyuan Hu, Ran Wei et al. · 2020 · Frontiers in Immunology
- Glutaminase in microglia: A novel regulator of neuroinflammationLu Ding, Xiaonan Xu, Congcong Li, Yi Wang, Xiaohuan Xia, Jialin Zheng · 2020 · Brain Behavior and Immunity
- The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a β-thalassemia mouse modelAlessandro Mattè, Enrica Federti, Charles K.-H. Kung, Penelope A. Kosinski, Rohini Narayanaswamy, Roberta Russo, Giorgia Federico, Francesca Carlomagno, María Andrea Desbats, Leonardo Salviati et al. · 2021 · Journal of Clinical Investigation
- Biodegradable Hollow‐Structured Nanozymes Modulate Phenotypic Polarization of Macrophages and Relieve Hypoxia for Treatment of OsteoarthritisHao Xiong, Yongzheng Zhao, Qinyuan Xu, Xue Xie, Jianrong Wu, Bing Quan Hu, Shuai Chen, Xiaojun Cai, Yuanyi Zheng, Cunyi Fan · 2022 · Small
- Mitochondria as Molecular Platforms Integrating Multiple Innate Immune SignalingsMarie Monlun, Caroline Hyernard, Patrick Blanco, Lydia Lartigue, Benjamin Faustin · 2016 · Journal of Molecular Biology
- Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid ArthritisTrudy McGarry, Monika Biniecka, Wei Gao, Deborah Cluxton, Mary Canavan, Siobhan C. Wade, Sarah M. Wade, Lorna Gallagher, Carl Kieran Orr, Douglas James Veale et al. · 2017 · Scientific Reports
- Can the emerging field of immunometabolism provide insights into neuroinflammation?Marina A. Lynch · 2019 · Progress in Neurobiology
- Pyruvate Kinase M2 Modulates the Glycolysis of Chondrocyte and Extracellular Matrix in OsteoarthritisXiaobo Yang, Weiping Chen, Xiang Zhao, Linwei Chen, Wanli Li, Jisheng Ran, Lidong Wu · 2018 · DNA and Cell Biology
- A sweet spot for macrophages: Focusing on polarizationDepeng Yang, Lijun Yang, Jialing Cai, Xibo Hu, Huaxin Li, Xiaoqing Zhang, Xiaohan Zhang, Xinghe Chen, Haiyang Dong, Huan Nie et al. · 2021 · Pharmacological Research
- Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responsesPranvera Sadiku, Joseph A. Willson, Rebecca S. Dickinson, Fiona A Murphy, A.J. Harris, Amy Lewis, David Sammut, Ananda S. Mirchandani, Eilíse M. Ryan, Emily Watts et al. · 2017 · Journal of Clinical Investigation
- Extracellular glucose is crucially involved in the fate decision of LPS-stimulated RAW264.7 murine macrophage cellsToshihiko Aki, Takeshi Funakoshi, Kanako Noritake, Kana Unuma, Koichi Uemura · 2020 · Scientific Reports
- The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophilsJuliana Escher Toller-Kawahisa, Carlos Hiroji Hiroki, Camila Meirelles Souza Silva, Daniele C. Nascimento, Gabriel Azevedo Públio, Timna Varela Martins, Luis Eduardo Alves Damasceno, Flavio Protasio Veras, Paula Ramos Viacava, Fábio Yuji Sukesada et al. · 2023 · Nature Communications
- Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 PhenotypeByong-Keol Min, Sungmi Park, Hyeon‐Ji Kang, Dong Wook Kim, Hye Jin Ham, Chae‐Myeong Ha, Byung-Jun Choi, Jung Yi Lee, Chang Joo Oh, Eun Kyung Yoo et al. · 2019 · Frontiers in Immunology
- SGLT2 inhibitor counteracts NLRP3 inflammasome via tubular metabolite itaconate in fibrosis kidneyQingqing Ke, Caifeng Shi, Yunhui Lv, Lulu Wang, Jing Luo, Lei Jiang, Junwei Yang, Yang Zhou · 2021 · The FASEB Journal
- Palmitoleic acid reduces the inflammation in LPS ‐stimulated macrophages by inhibition of NF κB, independently of PPAR sCamila Oliveira de Souza, Alexandre Abílio de Souza Teixeira, Luana Amorim Biondo, Loreana Sanches Silveira, Philip C. Calder, José Cesar Rosa Neto · 2017 · Clinical and Experimental Pharmacology and Physiology
- Cell-Autonomous Metabolic Reprogramming in HypoxiaLuana Schito, Sergio Rey · 2017 · Trends in Cell Biology
- Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiationQi Yuan, Jiao Miao, Qianqian Yang, Li Fang, Yi Fang, Hao Ding, Yang Zhou, Lei Jiang, Chunsun Dai, Ke Zen et al. · 2020 · Cell Death and Disease
- Immunometabolism and Sepsis: A Role for HIF?Susan F. Fitzpatrick · 2019 · Frontiers in Molecular Biosciences
- The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognitionGareth A. Prosser, Julius Brandenburg, Norbert Reiling, Clifton E. Barry, Robert John Wilkinson, Katalin Andrea Wilkinson · 2016 · Microbes and Infection
- The immunoinhibitory PD-1/PD-L1 pathway in inflammatory blood vessel diseaseCornelia M. Weyand, Gerald J. Berry, Jörg J. Goronzy · 2017 · Journal of Leukocyte Biology
- Flavonoid-mediated immunomodulation of human macrophages involves key metabolites and metabolic pathwaysLuís Mendes, Vítor M. Gaspar, Tiago Conde, João Filipe Mano, Iola F. Duarte · 2019 · Scientific Reports
- Metabolic Reprogramming in Mitochondria of Myeloid CellsHao Zuo, Yihong Wan · 2019 · Cells
- Targeting Cancer Cells and Tumor Microenvironment in Preclinical and Clinical Models of Hodgkin Lymphoma Using the Dual PI3Kδ/γ Inhibitor RP6530Silvia L. Locatelli, Giuseppa Careddu, Simone Serio, Francesca Maria Consonni, Akihiro Maeda, Srikant Viswanadha, Swaroop V.S. Vakkalanka, Luca Castagna, Armando Santoro, Paola Allavena et al. · 2018 · Clinical Cancer Research
- Immunometabolism: A novel perspective of liver cancer microenvironment and its influence on tumor progressionQi Zhang, Yu Lou, Xueli Bai, Tingbo Liang · 2018 · World Journal of Gastroenterology
- Pyruvate Kinase M2 Tetramerization Protects against Hepatic Stellate Cell Activation and Liver FibrosisDandan Zheng, Yuchuan Jiang, Chen Qu, Hui Yuan, Kaishun Hu, Lu He, Peng Chen, Jinying Li, Mengxian Tu, Lehang Lin et al. · 2020 · American Journal Of Pathology
- Protective Effect of Mitochondria-Targeted Antioxidants against Inflammatory Response to Lipopolysaccharide Challenge: A ReviewEkaterina M. Fock, Rimma G. Parnova · 2021 · Pharmaceutics
- Lactate-mediated metabolic reprogramming of tumor-associated macrophages: implications for tumor progression and therapeutic potentialXiaohan Jin, Ni Zhang, Tinghao Yan, Jingyang Wei, Lingli Hao, Changgang Sun, Haibo Zhao, Shulong Jiang · 2025 · Frontiers in Immunology
- The Macrophage Response Is Driven by Mesenchymal Stem Cell-Mediated Metabolic ReprogrammingLuque-Campos, Noymar, Bustamante-Barrientos, Felipe A., Pradenas, Carolina, García, Cynthia, Araya, María Jesús, Bohaud, Candice, Contreras-López, Rafael, Elizondo-Vega, Roberto, Djouad, Farida, Luz-Crawford, Patricia et al. · 2021 · Frontiers in Immunology
- Lactate and Lactylation in the Brain: Current Progress and PerspectivesRuobing Li, Yi Yang, Haoyu Wang, Tingting Zhang, Fangfang Duan, Kaidi Wu, Siyu Yang, Ke Xu, Xicheng Jiang, Xiaowei Sun · 2023 · Cellular and Molecular Neurobiology
- Post-translational protein lactylation modification in health and diseases: a double-edged swordHang Gong, Huang Zhong, Long Cheng, Liangping Li, Dekui Zhang · 2024 · Journal of Translational Medicine
- Peroxidase-Mimicking Nanoassembly Mitigates Lipopolysaccharide-Induced Endotoxemia and Cognitive Damage in the Brain by Impeding Inflammatory Signaling in MacrophagesSanthosh Kalash Rajendrakumar, Vishnu Revuri, Manikandan Samidurai, Adityanarayan Mohapatra, Jae Hyuk Lee, Palanivel Ganesan, Jihoon Jo, Yong-Kyu Lee, In‐Kyu Park · 2018 · Nano Letters
- Multistability in Macrophage Activation Pathways and Metabolic ImplicationsCarsten Geiß, Elvira Salas, Jose Andres Guevara-Coto, Anne Régnier‐Vigouroux, Rodrigo Antonio Mora-Rodríguez · 2022 · Cells