Role of obstructive sleep apnea in metabolic risk in PCOS
Open accessAbstract
Women with polycystic ovary syndrome (PCOS) have a substantially increased risk for diabetes and cardiovascular disease. Obstructive sleep apnea (OSA) is the most common sleep disorder in PCOS. Recent population-based studies indicate a high incidence of OSA among adult women with PCOS. Obesity and increasing age are the main factors for this association. There is strong evidence indicating that OSA is an important modulator of metabolic risk in the general population. There is also some evidence to suggest that OSA may contribute to insulin resistance and glucose intolerance among women PCOS, and thus increase their metabolic risk. The potential mechanisms for adverse metabolic consequences of OSA are likely to be multiple. Whether treatment of OSA in PCOS improves metabolic outcomes requires further rigorous research.
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- Authors
- Sam, S., & Tasali, E.
- Affiliations
- University of Chicago (US)
- Corresponding author
- Tasali, Esra
- Venue
- Current Opinion in Endocrine and Metabolic Research
- Publisher
- Elsevier BV
- Published
- 2021-04
- Volume
- 17
- Pages
- 46-51
- ISSN
- 2451-9650 (ISSN-L)
- PMC
- PMC8341449
- OpenAlex
- W3127015768
- Cited by
- 21
- References
- 67
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 4 · 2023: 4 · 2022: 1
- FWCI
- 0.30
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Current Opinion in Endocrine and Metabolic Research (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- University of Chicago
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- obstructive sleep apnea, polycystic ovary syndrome, metabolic risk, insulin resistance, impaired glucose tolerance, diabetes risk, cardiovascular risk, obesity, sleep disorders, OSA treatment
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