Cytokines and growth factors in airway remodeling in asthma

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

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A Critical Role for Eosinophils in Allergic Airways Remodeling

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Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics

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Interleukin‐13 in asthma pathogenesis

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Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung

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The mechanisms, diagnosis, and management of severe asthma in adults

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Inhibition of airway remodeling in IL-5–deficient mice

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Airway remodeling contributes to the progressive loss of lung function in asthma: An overview

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Mast cells can promote the development of multiple features of chronic asthma in mice

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Manipulation of Allergen-Induced Airway Remodeling by Treatment with Anti-TGF-β Antibody: Effect on the Smad Signaling Pathway

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Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology

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A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation

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Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology

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Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling

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Increased expression of ADAM33 and ADAM8 with disease progression in asthma

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Allergen-induced peribronchial fibrosis and mucus production mediated by IκB kinase β-dependent genes in airway epithelium

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Inhibition of Allergen-Induced Airway Remodeling in Smad 3-Deficient Mice

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Mechanisms of induction of airway smooth muscle hyperplasia by transforming growth factor-β

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Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

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IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells

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Persistent Effects Induced by IL-13 in the Lung

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The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts

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IL-4 Receptor Signaling in Clara Cells Is Required for Allergen-Induced Mucus Production

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Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice

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Effects of a Low-Molecular-Weight CCR-3 Antagonist on Chronic Experimental Asthma

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Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice

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Reversal of airway inflammation and remodeling in asthma by a bispecific antibody fragment linking CCR3 to CD300a

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Eosinophils and CCR3 Regulate Interleukin-13 Transgene-Induced Pulmonary Remodeling

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Chronic exposure to TNF-α increases airway mucus gene expression in vivo

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ADAM33 Is Not Essential for Growth and Development and Does Not Modulate Allergic Asthma in Mice

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Therapeutic administration of Budesonide ameliorates allergen‐induced airway remodelling

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Immunostimulatory DNA inhibits allergen-induced peribronchial angiogenesis in mice

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The development of allergic inflammation

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Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

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Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

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The airway epithelium: soldier in the fight against respiratory viruses

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Commonality of the IL-4/IL-13 pathway in atopic diseases

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Remodeling in asthma

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Role of Transforming Growth Factor–β in Airway Remodeling in Asthma

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Regulatory T Cells in Asthma

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Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance

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Inhaled Multiwalled Carbon Nanotubes Potentiate Airway Fibrosis in Murine Allergic Asthma

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Eosinophils in innate immunity: an evolving story

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The potential of biologics for the treatment of asthma

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Th9 and allergic disease

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Remodeling in Asthma

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Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity

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T helper cytokines in dry eye disease

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Airway remodeling in asthma

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STAT6 and lung inflammation

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Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease

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Foxa3 Induces Goblet Cell Metaplasia and Inhibits Innate Antiviral Immunity

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The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation

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Proinflammatory and Profibrotic Mediators: Principal Effectors of Leiomyoma Development as a Fibrotic Disorder

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Diagnosis and management of eosinophilic asthma: a US perspective

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Pathogenic memory type Th2 cells in allergic inflammation

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Anti-IgE treatment, airway inflammation and remodelling in severe allergic asthma: current knowledge and future perspectives

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Lactobacillus paracasei feeding improves immune control of influenza infection in mice

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Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung

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Interleukin-13–Induced Mucous Metaplasia Increases Susceptibility of Human Airway Epithelium to Rhinovirus Infection

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Dual Transcriptomic Profiling of Host and Microbiota during Health and Disease in Pediatric Asthma

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Adoptive Transfer of Induced-Treg Cells Effectively Attenuates Murine Airway Allergic Inflammation

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Interactions of airway epithelium with protease allergens in the allergic response

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Stem cells and lung regeneration

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Epigenetic regulation of T‐helper cell differentiation, memory, and plasticity in allergic asthma

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The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice

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Pulmonary vascular changes in asthma and COPD

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Brain‐derived neurotrophic factor induces proliferation of human airway smooth muscle cells

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Allergen-Induced Airway Remodeling Is Impaired in Galectin-3–Deficient Mice

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FOXM1 Promotes Allergen-Induced Goblet Cell Metaplasia and Pulmonary Inflammation

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Leptin Enhances TH2 and ILC2 Responses in Allergic Airway Disease

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Cell Cycle Arrest by Transforming Growth Factor β1 Enhances Replication of Respiratory Syncytial Virus in Lung Epithelial Cells

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The Role of Transforming Growth Factor-β (TGF-β) in Asthma and Chronic Obstructive Pulmonary Disease (COPD)

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Natural history of asthma: Persistence versus progression—does the beginning predict the end?

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Acute Severe Asthma in Adolescent and Adult Patients: Current Perspectives on Assessment and Management

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Biological Therapies of Severe Asthma and Their Possible Effects on Airway Remodeling

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Active ingredients from Chinese medicine plants as therapeutic strategies for asthma: Overview and challenges

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Developing a tissue-engineered model of the human bronchiole

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Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma

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PI3Kγ-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling

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Airway innate lymphoid cells in the induction and regulation of allergy

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DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma

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Review: Tissue remodeling and angiogenesis in asthma: the role of the eosinophil

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Leptin Promotes Allergic Airway Inflammation through Targeting the Unfolded Protein Response Pathway

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Anoctamin 1 in secretory epithelia

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The Other T Helper Cells in Asthma Pathogenesis

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Vitamin D as an adjunctive therapy in asthma. Part 1: A review of potential mechanisms

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MAPK Regulation of IL-4/IL-13 Receptors Contributes to the Synergistic Increase in CCL11/Eotaxin-1 in Response to TGF-β1 and IL-13 in Human Airway Fibroblasts

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Inhibition of airway remodeling and inflammatory response by Icariin in asthma

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Severe Persistent Allergic Rhinitis. Inflammation but No Histologic Features of Structural Upper Airway Remodeling

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Immunomodulatory role of oral microbiota in inflammatory diseases and allergic conditions

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Vitamin D Attenuates Cytokine‐Induced Remodeling in Human Fetal Airway Smooth Muscle Cells

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Deficiency of Endothelial Heparan Sulfates Attenuates Allergic Airway Inflammation

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Th9: A New Player in Asthma Pathogenesis?

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Long-Term Efficacy and Clinical Remission After Benralizumab Treatment in Patients with Severe Eosinophilic Asthma: A Retrospective Study

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Inflammatory Response Mechanisms Exacerbating Hypoxemia in Coexistent Pulmonary Fibrosis and Sleep Apnea

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Molecular changes during TGFβ-mediated lung fibroblast-myofibroblast differentiation: implication for glucocorticoid resistance

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Eosinophils in Fungus-Associated Allergic Pulmonary Disease

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Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice

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Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Regulates Hallmark Features of Airways Remodeling in Allergic Airways Disease

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IL-5 antagonism reverses priming and activation of eosinophils in severe eosinophilic asthma

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Beneficial effects of ursodeoxycholic acid via inhibition of airway remodelling, apoptosis of airway epithelial cells, and Th2 immune response in murine model of chronic asthma

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Cordycepin inhibits airway remodeling in a rat model of chronic asthma

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Role of vascular endothelial growth factor antagonism on airway remodeling in asthma

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Bioprinting stem cells: building physiological tissues one cell at a time

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Nasal and bronchial airway epithelial cell mediator release in children

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Mechanisms of BDNF regulation in asthmatic airway smooth muscle

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Systemic and exhaled cytokine and chemokine profiles are associated with the development of bronchiolitis obliterans syndrome

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l-2-Oxothiazolidine-4-Carboxylic Acid or α-Lipoic Acid Attenuates Airway Remodeling: Involvement of Nuclear Factor-κB (NF-κB), Nuclear Factor Erythroid 2p45-Related Factor-2 (Nrf2), and Hypoxia-Inducible Factor (HIF)

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A 3D epithelial–mesenchymal co-culture model of human bronchial tissue recapitulates multiple features of airway tissue remodeling by TGF-β1 treatment

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Orchestration of epithelial-derived cytokines and innate immune cells in allergic airway inflammation

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Anti‑VEGF treatment suppresses remodeling factors and restores epithelial barrier function through the E‑cadherin/β‑catenin signaling axis in experimental asthma models

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Type 2-High Severe Asthma with and without Bronchiectasis: A Prospective Observational Multicentre Study

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Therapeutic Potential of Combining IL-6 and TNF Blockade in a Mouse Model of Allergic Asthma

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Effects of antenatal lipopolysaccharide and postnatal hyperoxia on airway reactivity and remodeling in a neonatal mouse model

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Sevoflurane Prevents Airway Remodeling via Downregulation of VEGF and TGF-β1 in Mice with OVA-Induced Chronic Airway Inflammation

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In vitro human cell-based models to study airway remodeling in asthma

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Mega-dose vitamin C attenuated lung inflammation in mouse asthma model

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Pathological axes of wound repair: Gastrulation revisited

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Role of Innate Lymphoid Cells in Lung Disease.

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The leukotriene receptor antagonist pranlukast attenuates airway remodeling by suppressing TGF-β signaling

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Cell-Free Biological Approach for Corneal Stromal Wound Healing

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The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice

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IFN‐γ elevates airway hyper‐responsiveness via up‐regulation of neurokinin A/neurokinin‐2 receptor signaling in a severe asthma model

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Administration of Pigment Epithelium-Derived Factor Inhibits Airway Inflammation and Remodeling in Chronic OVA-Induced Mice via VEGF Suppression

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Sex Steroids Influence Brain-Derived Neurotropic Factor Secretion From Human Airway Smooth Muscle Cells

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Elevated levels of NO are localized to distal airways in asthma

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Cigarette Smoke Extract-induced Reduction in Migration and Contraction in Normal Human Bronchial Smooth Muscle Cells

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Immunologic and inflammatory mechanisms that drive asthma progression to remodeling

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Bronchial cytokines and growth factors augment fibroblast-induced airway remodeling in adult asthmatics

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Role of Transforming Growth Factor–β in Airway Remodeling in Asthma

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Reasearch progress of airway remodeling in bronchial asthma

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