Cited by 132Influenza Virus Research StudiesImmune Response and InflammationRespiratory viral infections research

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The immunology of influenza virus-associated bacterial pneumonia.

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Robinson, Keven M, Kolls, Jay K, Alcorn, John F·2015·Current Opinion in Immunology

DOI 10.1016/j.coi.2015.02.002PMC PMC4444379

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Abstract

Infection with influenza virus has been a significant cause of morbidity and mortality for more than a hundred years. Severe disease and increased mortality often results from bacterial super-infection of patients with influenza virus infection. Preceding influenza infection alters the host's innate and adaptive immune responses, allowing increased susceptibility to secondary bacterial pneumonia. Recent advances in the field have helped to define how influenza alters the immune response to bacteria through the dysregulation of phagocytes, antimicrobial peptides, and lymphocytes. Viral-induced interferons play a key role in altering the phenotype of the immune response. Potential genetic modifiers of disease will help to define additional immunologic mechanisms that predispose to viral, bacterial super-infection with the overarching goal of developing effective therapeutic strategies to prevent and treat disease.

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Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D. S., Weinrauch, Y., & Zychlinsky, A. (2004) · Science · doi:10.1126/science.1092385 · Cited by 10,268
Novel cell death program leads to neutrophil extracellular traps
Fuchs, T. A., Abed, U., Goosmann, C., Hurwitz, R., Schulze, I., Wahn, V., Weinrauch, Y., Brinkmann, V., & Zychlinsky, A. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200606027 · Cited by 3,197
Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness
Morens, D. M., Taubenberger, J. K., & Fauci, A. S. (2008) · The Journal of Infectious Diseases · doi:10.1086/591708 · Cited by 1,625 · cited 1×
“During the 1918 pandemic of influenza A virus H1N1, more than 50 million people died from influenza and bacterial super-infection [1].”
Background
Extracellular histones are major mediators of death in sepsis
Xu, J., Zhang, X., Pelayo, R., Monestier, M., Ammollo, C. T., Semeraro, F., Taylor, F. B., Esmon, N. L., Lupu, F., & Esmon, C. T. (2009) · Nature Medicine · doi:10.1038/nm.2053 · Cited by 1,540
Community-associated meticillin-resistant Staphylococcus aureus
DeLeo, F. R., Otto, M. J., Kreiswirth, B. N., & Chambers, H. F. “. (2010) · The Lancet · doi:10.1016/s0140-6736(09)61999-1 · Cited by 1,534
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
Monticelli, L. A., Sonnenberg, G. F., Abt, M. C., Alenghat, T., Ziegler, C. G. K., Doering, T. A., Angelosanto, J., Laidlaw, B. J., Yang, C. Y., Sathaliyawala, T., et al. (2011) · Nature Immunology · doi:10.1038/ni.2131 · Cited by 1,327
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
Monticelli (2011) · PubMed · doi:10.1031/ni.2131 · Cited by 1,286
STAT3 Mutations in the Hyper-IgE Syndrome
Holland, S. M., DeLeo, F. R., Elloumi, H. Z., Hsu, A. P., Uzel, G., Brodsky, N. N., Freeman, A. F., Demidowich, A. P., Davis, J., Turner, M. L. C., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa073687 · Cited by 1,233
Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis
Narasaraju, T., Yang, E., Samy, R. P., Ng, H. H., Poh, W. P., Liew, A.-A., Phoon, M. C., van Rooijen, N., & Chow, V. T. K. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2011.03.013 · Cited by 918
Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection
Sun, K., & Metzger, D. W. (2008) · Nature Medicine · doi:10.1038/nm1765 · Cited by 587
Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice
Shahangian, A., Chow, E. K., Tian, X., Kang, J. R., Ghaffari, A., Liu, S. Y., Belperio, J. A., Cheng, G., & Deng, J. C. (2009) · Journal of Clinical Investigation · doi:10.1172/jci35412 · Cited by 479
2009 Pandemic Influenza A (H1N1)
Shieh, W.-J., Blau, D. M., Denison, A. M., DeLeon-Carnes, M., Adem, P., Bhatnagar, J., Sumner, J., Liu, L., Patel, M., Batten, B., et al. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.100115 · Cited by 429
Pulmonary Pathologic Findings of Fatal 2009 Pandemic Influenza A/H1N1 Viral Infections
Gill, J. R., Sheng, Z.-M., Ely, S. F., Guinee, D. G., Beasley, M. B., Suh, J., Deshpande, C., Mollura, D. J., Morens, D. M., Bray, M., et al. (2010) · Archives of Pathology & Laboratory Medicine · doi:10.5858/134.2.235 · Cited by 426
Infectious Diseases in Patients with IRAK-4, MyD88, NEMO, or IκBα Deficiency
Pïcard, C., Casanova, J., & Puel, A. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00001-11 · Cited by 408
Global epidemiology of community-associated methicillin resistant Staphylococcus aureus (CA-MRSA)
Mediavilla, J. R., Chen, L., Mathema, B., & Kreiswirth, B. N. (2012) · Current Opinion in Microbiology · doi:10.1016/j.mib.2012.08.003 · Cited by 400
Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection
Didierlaurent, A., Goulding, J., Patel, S., Snelgrove, R., Low, L., Bebien, M., Lawrence, T., van Rijt, L. S., Lambrecht, B. N., Sirard, J.-C., et al. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20070891 · Cited by 399
Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections
Ghoneim, H. E., Thomas, P. G., & McCullers, J. A. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300014 · Cited by 394
Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States.
Rice, T. W., Rubinson, L., Uyeki, T. M., Vaughn, F. L., John, B. B., Miller, R. R., Higgs, E., Randolph, A. G., Smoot, B. E., & Thompson, B. T. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182416f23 · Cited by 391
Influenza A inhibits Th17-mediated host defense against bacterial pneumonia in mice.
Kudva, A., Scheller, E. V., Robinson, K. M., Crowe, C. R., Choi, S. M., Slight, S. R., Khader, S. A., Dubin, P. J., Enelow, R. I., Kolls, J. K., et al. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1002194 · Cited by 346
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IL-10 Is an Important Mediator of the Enhanced Susceptibility to Pneumococcal Pneumonia after Influenza Infection
van der Sluijs, K. F., van Elden, L. J. R., Nijhuis, M., Schuurman, R., Pater, J. M., Florquin, S., Goldman, M., Jansen, H. M., Lutter, R., & van der Poll, T. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.12.7603 · Cited by 338
Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice
Nakamura, S., Davis, K. M., & Weiser, J. N. (2011) · Journal of Clinical Investigation · doi:10.1172/jci57762 · Cited by 280
Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza
Palacios, G., Hornig, M., Cisterna, D., Savji, N., Bussetti, A. V., Kapoor, V., Hui, J., Tokarz, R., Briese, T., Baumeister, E., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008540 · Cited by 275
Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome
Minegishi, Y., Saitō, M., Nagasawa, M., Takada, H., Hara, T., Tsuchiya, S., Agematsu, K., Yamada, M., Kawamura, N., Ariga, T., et al. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20082767 · Cited by 249
Both Influenza-Induced Neutrophil Dysfunction and Neutrophil-Independent Mechanisms Contribute to Increased Susceptibility to a Secondary Streptococcus pneumoniae Infection
McNamee, L. A., & Harmsen, A. G. (2006) · Infection and Immunity · doi:10.1128/iai.00789-06 · Cited by 233
Critically Ill Children During the 2009–2010 Influenza Pandemic in the United States
Randolph, A. G., Vaughn, F., Sullivan, R., Rubinson, L., Thompson, B. T., Yoon, G., Smoot, E., Rice, T. W., Loftis, L. L., Helfaer, M., et al. (2011) · Pediatrics · doi:10.1542/peds.2011-0774 · Cited by 222
Surveillance for pediatric deaths associated with 2009 pandemic influenza A (H1N1) virus infection - United States, April-August 2009.
Shannon, S., Louie, J. K., Siniscalchi, A. J., Rico, E., Richter, D., Hernandez, R. G., Lynfield, R., McHugh, L., Waters, C., Lee, E.-A. K., et al. (2009) · MMWR Morbidity and Mortality Weekly Report · Cited by 217
Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung
Small, C.-L., Shaler, C. R., McCormick, S., Jeyanathan, M., Damjanovic, D., Brown, E. G., Arck, P., Jordana, M., Kaushic, C., Ashkar, A. A., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902772 · Cited by 216
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Li, W., Moltedo, B., & Moran, T. M. (2012) · Journal of Virology · doi:10.1128/jvi.01269-12 · Cited by 191
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Wang, W., Levy, D. E., & Lee, C. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1004128 · Cited by 179
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Ivanov, S., Renneson, J., Fontaine, J., Barthélémy, A., Paget, C., Fernandez, É. M., Blanc, F., Trez, C. D., Maele, L. V., Dumoutier, L., et al. (2013) · Journal of Virology · doi:10.1128/jvi.02943-12 · Cited by 169
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Schliehe, C., Flynn, E. K., Vilagos, B., Richson, U., Swaminathan, S., Bošnjak, B., Bauer, L., Kandasamy, R. K., Griesshammer, I. M., Kosack, L., et al. (2014) · Nature Immunology · doi:10.1038/ni.3046 · Cited by 147
Influenza A Virus Exacerbates Staphylococcus aureus Pneumonia in Mice by Attenuating Antimicrobial Peptide Production
Robinson, K. M., McHugh, K. J., Mandalapu, S., Clay, M. E., Lee, B., Scheller, E. V., Enelow, R. I., Chan, Y. R., Kolls, J. K., & Alcorn, J. F. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit527 · Cited by 131
Self-citation
Surveillance for pediatric deaths associated with 2009 pandemic influenza A (H1N1) virus infection - United States, April-August 2009.
(2009) · PubMed · Cited by 130
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Robinson, K. M., Choi, S. M., McHugh, K. J., Mandalapu, S., Enelow, R. I., Kolls, J. K., & Alcorn, J. F. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1301237 · Cited by 126
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In vivo and in vitro studies on the roles of neutrophil extracellular traps during secondary pneumococcal pneumonia after primary pulmonary influenza infection
Moorthy, A. N., Narasaraju, T., Rai, P., Perumalsamy, R., Tan, K. B., Wang, S., Engelward, B. P., & Chow, V. T. K. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00056 · Cited by 125
Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice
Albiger, B., Sandgren, A., Katsuragi, H., Meyer‐Hoffert, U., Beiter, K., Wartha, F., Hornef, M. W., Normark, S. J., & Normark, B. H. (2005) · Cellular Microbiology · doi:10.1111/j.1462-5822.2005.00578.x · Cited by 118
The impact of bacterial and viral co‐infection in severe influenza
Blyth, C. C., Webb, S. A. R., Kok, J., Dwyer, D. E., van Hal, S. J., Foo, H., Ginn, A. N., Kesson, A. M., Seppelt, I., Iredell, J. R., et al. (2013) · Influenza and Other Respiratory Viruses · doi:10.1111/j.1750-2659.2012.00360.x · Cited by 117
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Choi, S.-M., McAleer, J. P., Zheng, M., Pociask, D. A., Kaplan, M. H., Qin, S., Reinhart, T. A., & Kolls, J. K. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20120260 · Cited by 116
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Goulding, J., Godlee, A., Vekaria, S., Hilty, M., Snelgrove, R. J., & Hussell, T. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir467 · Cited by 115
Influenza‐Induced Expression of Indoleamine 2,3‐Dioxygenase Enhances Interleukin‐10 Production and Bacterial Outgrowth during Secondary Pneumococcal Pneumonia
van der Sluijs, K. F., Nijhuis, M., Levels, J. H. M., Florquin, S., Mellor, A. L., Jansen, H. M., der Poll, T. V., & Lutter, R. (2006) · The Journal of Infectious Diseases · doi:10.1086/498911 · Cited by 111
MyD88 Signaling Is Indispensable for Primary Influenza A Virus Infection but Dispensable for Secondary Infection
Seo, S., Kwon, H.-J., Song, J.-H., Byun, Y.-H., Seong, B. L., Kawai, T., Akira, S., & Kweon, M. (2010) · Journal of Virology · doi:10.1128/jvi.01675-10 · Cited by 101
CCR2-Antagonist Prophylaxis Reduces Pulmonary Immune Pathology and Markedly Improves Survival during Influenza Infection
Lin, K. L., Sweeney, S., Kang, B. D., Ramsburg, E. A., & Gunn, M. D. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001002 · Cited by 92
Activation of IL‐27 signalling promotes development of postinfluenza pneumococcal pneumonia
Cao, J., Wang, D., Xu, F., Gong, Y., Wang, H., Song, Z., Li, D., Zhang, H., Li, D., Zhang, L., et al. (2013) · EMBO Molecular Medicine · doi:10.1002/emmm.201302890 · Cited by 87
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Karlström, Å., Heston, S. M., Boyd, K. L., TUOMANEN, E. I., & McCullers, J. A. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir522 · Cited by 85
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Niemann, S., Ehrhardt, C., Medina, E., Warnking, K., Tuchscherr, L. P. N., Heitmann, V., Ludwig, S., Peters, G., & Löffler, B. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis468 · Cited by 83
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Tian, X., Xu, F., Lung, W. Y., Meyerson, C., Ghaffari, A. A., Cheng, G., & Deng, J. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041879 · Cited by 77
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Bedoya, F., Cheng, G., Leibow, A., Zakhary, N., Weissler, K. A., Garcia, V., Aitken, M., Kropf, E., Garlick, D. S., Wherry, E. J., et al. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203302 · Cited by 75
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Nguyen, T., Kyle, U. G., Jaimon, N., Tcharmtchi, M. H., Coss-Bu, J. A., Lam, F., Teruya, J., & Loftis, L. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e318260c7f8 · Cited by 54
A Novel Outbred Mouse Model of 2009 Pandemic Influenza and Bacterial Co-Infection Severity
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Rynda‐Apple, A., Harmsen, A. L., Erickson, A. S., Larson, K., Morton, R. V., Richert, L. E., & Harmsen, A. G. (2014) · European Journal of Immunology · doi:10.1002/eji.201444582 · Cited by 36
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Tanaka, A., Nakamura, S., Seki, M., Fukudome, K., Iwanaga, N., Imamura, Y., Miyazaki, T., Izumikawa, K., Kakeya, H., Yanagihara, K., et al. (2013) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00010-13 · Cited by 29
Linezolid Decreases Susceptibility to Secondary Bacterial Pneumonia Postinfluenza Infection in Mice Through its Effects on IFN-γ
Deckman, J. M., Mattingly, C. A., Birket, S. E., Hoskins, S., Ho, T. N., Garvy, B. A., & Feola, D. J. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300180 · Cited by 22
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Liu, X., He, Y., Xiao, K., White, J. R., Fusco, D. N., & Papanicolaou, G. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057483 · Cited by 20
Limited Anti-Inflammatory Role for Interleukin-1 Receptor Like 1 (ST2) in the Host Response to Murine Postinfluenza Pneumococcal Pneumonia
Blok, D. C., van der Sluijs, K. F., Florquin, S., de Boer, O. J., Veer, C. V. ′., de Vos, A. F., & van der Poll, T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058191 · Cited by 10

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Authors: Robinson, K. M., Kolls, J. K., & Alcorn, J. F.
Affiliations: University of Pittsburgh Medical Center (US)
Children's Hospital of Pittsburgh (US)
ORCID: Robinson, Keven M
Kolls, Jay K
Alcorn, John F
Venue: Current Opinion in Immunology
Publisher: Elsevier BV
Published: 2015-06
Volume: 34
Pages: 59-67
ISSN: 0952-7915 (ISSN-L)
DOI: 10.1016/j.coi.2015.02.002
PMC: PMC4444379
OpenAlex: W2088299538
Cited by: 132
References: 61
Citations by year: 2026: 3 · 2025: 11 · 2024: 11 · 2023: 15 · 2022: 12 · 2021: 10 · 2020: 15 · 2019: 16 · 2018: 10 · 2017: 12 · 2016: 14 · 2015: 3
FWCI: 1.69
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Current Opinion in Immunology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: Parker B. Francis Fellowship (KMR)
NIH (R01 HL107380, R37 HL079142)
Topics: Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
Keywords: influenza virus, secondary bacterial infection, secondary bacterial pneumonia, immune dysregulation, phagocytes, antimicrobial peptides, lymphocytes, interferon, genetic susceptibility, host immune response
MeSH terms: Animals, Humans, Influenza, Human, Orthomyxoviridae, Orthomyxoviridae Infections, Phagocytes, Staphylococcus aureus, Streptococcus pneumoniae, Pneumonia, Bacterial

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The immunology of influenza virus-associated bacterial pneumonia.

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