Laminar processing in the visual cortical column.

Hirsch, Judith A; Martinez, Luis M

doi:10.1016/j.conb.2006.06.014

Cited by 120Visual perception and processing mechanismsNeuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Laminar processing in the visual cortical column.

Hirsch, Judith A, Martinez, Luis M·2006·Current Opinion in Neurobiology

DOI 10.1016/j.conb.2006.06.014

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Abstract

Sensory regions of neocortex are organized as arrays of vertical columns composed of cells that share similar response properties, with the orientation columns of the cat's visual cortex being the best known example. Interest in how sensitivity to different stimulus features first emerges in the columns and how this selectivity is refined by subsequent processing has fueled decades of research. A natural starting point in approaching these issues is anatomy. Each column traverses the six cortical layers and each layer has a unique pattern of inputs, intrinsic connections and outputs. Thus, it makes sense to explore the possibility of corresponding laminar differences in sensory function, that is, to examine relationships between morphology and physiology. In addition, to help identify general patterns of cortical organization, it is useful to compare results obtained from different sensory systems and diverse species. The picture that emerges from such comparisons is that each cortical layer serves a distinct role in sensory function. Furthermore, different cortices appear to share some common strategies for processing information but also have specialized mechanisms adapted for the demands of specific sensory tasks.

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Cells in layer 2/3 of the visual and barrel cortices strongly prefer richer stimuli, such as motion in the preferred direction, unlike cells in layer 4 that respond to more impoverished stimuli.
“Unlike cells in layer 4 that respond to more impoverished stimuli, cells in layer 2/3 of the visual and barrel cortices strongly prefer richer stimuli, such as motion in the preferred direction [47].”
From Towards a mathematical theory of cortical micro-circuits (2009) · cites this paper as [47]

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Authors: Hirsch, J. A., & Martinez, L. M.
Affiliations: University of Southern California (US)
Corresponding author: Hirsch, Judith A
Venue: Current Opinion in Neurobiology
Publisher: Elsevier BV
Published: 2006-08
Volume: 16
Issue: 4
Pages: 377-384
ISSN: 0959-4388 (ISSN-L)
DOI: 10.1016/j.conb.2006.06.014
OpenAlex: W2155643741
Cited by: 120
References: 103
Citations by year: 2026: 3 · 2025: 4 · 2024: 14 · 2023: 6 · 2022: 3 · 2021: 6 · 2020: 10 · 2019: 4 · 2018: 5 · 2017: 3 · 2016: 3 · 2015: 7 · 2014: 9 · 2013: 4 · 2012: 4
FWCI: 0.45
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Current Opinion in Neurobiology (publishedVersion)
PubMed (publishedVersion)
DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
Funders: National Institutes of Health
National Eye Institute (EY 09593)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords: visual cortex, cortical columns, orientation columns, cortical layers, sensory processing, cortical organization, cat visual cortex
MeSH terms: Animals, Cats, Humans, Nerve Net, Neural Inhibition, Synaptic Transmission, Neurons, Species Specificity, Visual Cortex, Visual Fields, Visual Pathways, Visual Perception

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Laminar processing in the visual cortical column.

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