Cited by 402Biofuel production and bioconversionAnaerobic Digestion and Biogas ProductionBioenergy crop production and management

Cellulosic ethanol: status and innovation

Open access
Lynd, Lee R, Liang, Xiaoyu, Biddy, Mary J, Allee, Andrew, Cai, Hao, Foust, Thomas, Himmel, Michael E, Laser, Mark S +2 more·2017·Current Opinion in Biotechnology

Abstract

Although the purchase price of cellulosic feedstocks is competitive with petroleum on an energy basis, the cost of lignocellulose conversion to ethanol using today's technology is high. Cost reductions can be pursued via either in-paradigm or new-paradigm innovation. As an example of new-paradigm innovation, consolidated bioprocessing using thermophilic bacteria combined with milling during fermentation (cotreatment) is analyzed. Acknowledging the nascent state of this approach, our analysis indicates potential for radically improved cost competitiveness and feasibility at smaller scale compared to current technology, arising from (a) R&D-driven advances (consolidated bioprocessing with cotreatment in lieu of thermochemical pretreatment and added fungal cellulase), and (b) configurational changes (fuel pellet coproduction instead of electricity, gas boiler(s) in lieu of a solid fuel boiler).

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Crossref · 10.1016/j.copbio.2017.03.008

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  • Advanced biofuel production costs are higher than their fossil counterparts.

    “Their production costs [19][20][21] however are higher than their fossil counterparts [22]”
  • The current cellulosic BP pathway is broadly consistent with the six pioneer commercial-scale cellulosic biorefineries that had been constructed worldwide as of 2017, with a combined nameplate annual production capacity of 450 million L.

    “This pathway is broadly consistent with the six pioneer commercial-scale cellulosic biorefineries that had been constructed worldwide as of 2017, with a combined nameplate annual production capacity of 450 million L ( 58 ).”
  • Continued research, development, and iterative limited-scale deployment of bioenergy and CCS systems are essential for realizing improvements and cost reductions in biorefining and CCS technology in support of existing renewable fuel mandates and in time for midcentury wide-scale deployment of CDR.

    “We note that continued research, development, and iterative limited-scale deployment of such systems are essential for realizing improvements and cost reductions in biorefining and CCS technology ( 58 , 59 ) in support of existing renewable fuel mandates and in time for the midcentury wide-scale deployment of CDR called for in many projections.”

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Research works printed but not linked: 12

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  2. [14]14. U.S. Department of Energy: Lignocellulosic Biomass for Advanced Biofuels and Bioproducts: Workshop Report . 2015. DOE SC-0170. - An examination of the scientific barriers to expanding the bioeconomy based on lignocellulosic feedstocks, including recognition of the continuing importance of the recalcitrance barrier as an impediment to cost-competitive production.
  3. [20]20. Lynd LR, Guss AM, Himmel ME, Beri D, Herring C, Holwerda EK, Murphy SJ, Olson DG, Paye J, Rydzak T, et al.: Advances in Consolidated Bioprocessing Using Clostridium thermocellum and Thermoanaerobacter saccharolyticum . In Industrial Biotechnology . . Wiley-VCH Verlag GmbH & Co. KGaA; 2017:365-394.
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  10. [40]40. Skovgaard PA, Thygesen LG, Jørgensen H, Cardona M, Tozzi E, McCarthy M, Siika-Aho M, Jeoh T: The role of endoglucanase and endoxylanase in liquefaction of hydrothermally pretreated wheat straw . Biotechnol. Prog. 2014, 30 :923-931. - A paper documenting the pronounced liquifaction and changes in physical properties that occurs during the initial stages of lignocellulose solubilization.
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Authors
Lynd, L. R., Liang, X., Biddy, M. J., Allee, A., Cai, H., Foust, T., Himmel, M. E., Laser, M. S., Wang, M., & Wyman, C. E.
Affiliations
  • Dartmouth College (US)
  • National Laboratory of the Rockies (US)
  • Argonne National Laboratory (US)
  • University of California, Riverside (US)
Corresponding author
Lynd, Lee R
Venue
Current Opinion in Biotechnology
Publisher
Elsevier BV
Published
2017-06
Volume
45
Pages
202-211
ISSN
0958-1669 (ISSN-L)
OpenAlex
W2615538334
Cited by
402
References
28
Citations by year
2026: 13 · 2025: 25 · 2024: 44 · 2023: 35 · 2022: 36 · 2021: 62 · 2020: 68 · 2019: 55 · 2018: 43 · 2017: 19 · 2016: 1
FWCI
4.06
Type
journal article
Language
en
Open access
Locations
  • Current Opinion in Biotechnology (acceptedVersion)
  • PubMed (publishedVersion)
  • OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • US Department of Energy Office of Biological and Environmental Research through the Bioenergy Science Center (DE-AC05-00OR22725)
  • Bioenergy Technology Office (BETO) of the Office of Energy Efficiency and Renewable Energy of the U.S. Department of Energy (DE-AC02-06CH11357)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
  • Physical Sciences › Engineering › Building and Construction › Anaerobic Digestion and Biogas Production
  • Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Bioenergy crop production and management
Keywords
cellulosic ethanol, lignocellulose conversion, consolidated bioprocessing, thermophilic bacteria, thermochemical pretreatment, fungal cellulases, process cost reduction, scale-up, biofuels
MeSH terms
Ethanol, Cellulase, Cellulose, Fermentation, Fungi, Lignin, Biofuels

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