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Metagenomic tools in microbial ecology research

Open access
Taş, Neslihan, de Jong, Anniek EE, Li, Yaoming, Trubl, Gareth, Xue, Yaxin, Dove, Nicholas C·2021·Current Opinion in Biotechnology
DOI 10.1016/j.copbio.2021.01.019
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Abstract

Ability to directly sequence DNA from the environment permanently changed microbial ecology. Here, we review the new insights to microbial life gleaned from the applications of metagenomics, as well as the extensive set of analytical tools that facilitate exploration of diversity and function of complex microbial communities. While metagenomics is shaping our understanding of microbial functions in ecosystems via gene-centric and genome-centric methods, annotating functions, metagenome assembly and binning in heterogeneous samples remains challenging. Development of new analysis and sequencing platforms generating high-throughput long-read sequences and functional screening opportunities will aid in harnessing metagenomes to increase our understanding of microbial taxonomy, function, ecology, and evolution in the environment.

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Metadata

Authors
Taş, N., de Jong, A. E., Li, Y., Trubl, G., Xue, Y., & Dove, N. C.
Venue
Current Opinion in Biotechnology
Publisher
Elsevier BV
Published
2021-02
Volume
67
Pages
184-191
ISSN
0958-1669 (ISSN-L)
DOI
10.1016/j.copbio.2021.01.019
OpenAlex
W3130750627
Cited by
198
References
6
FWCI
2.69
Type
journal article
Language
en
Open access
hybrid
Licence
Funders
  • Deltares
  • Lawrence Livermore National Laboratory
  • National Natural Science Foundation of China
  • Oak Ridge National Laboratory
  • Lawrence Berkeley National Laboratory

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CoChat. (2026). Citation check: Metagenomic tools in microbial ecology research. https://app.cochat.ai/papers/10.1016/j.copbio.2021.01.019
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Taş, N., de Jong, A. E., Li, Y., Trubl, G., Xue, Y., & Dove, N. C. (2021). Metagenomic tools in microbial ecology research. Current Opinion in Biotechnology. https://doi.org/10.1016/j.copbio.2021.01.019

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