Neurotrophic effects of antidepressant drugs

Neural consequences of enviromental enrichment

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Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments

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The cellular neurobiology of depression

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Functional anatomical correlates of antidepressant drug treatment assessed using PET measures of regional glucose metabolism

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Volumetric reduction in left subgenual prefrontal cortex in early onset depression

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Dose-Related Effects of Chronic Antidepressants on Neuroprotective Proteins BDNF, Bcl-2 and Cu/Zn-SOD in Rat Hippocampus

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Brain-Derived Neurotrophic Factor and Neuropsychiatric Disorders

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The antidepressant fluoxetine restores plasticity in the adult visual cortex

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The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity

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Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover proliferation, and survival in the adult dentate gyrus

Sairanen, M., Lucas, G., Ernfors, P., Castrén, M., & Castrén, E. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3741-04.2005 · Cited by 763 · see citing works

Role of neurotrophic factors in depression

CASTREN, E., VOIKAR, V, & RANTAMAKI, T. (2007) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2006.08.009 · Cited by 667 · see citing works

Is mood chemistry?

Castrén, E. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1629 · Cited by 563 · see citing works

Brain-derived neurotrophic factor in mood disorders and antidepressant treatments

Castrén, E., & Kojima, M. (2017) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.07.010 · Cited by 337 · see citing works

The Role of BDNF in Depression on the Basis of Its Location in the Neural Circuitry

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Nurturing brain plasticity: Impact of environmental enrichment

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Neuronal plasticity and antidepressant actions

Castrén, E., & Hen, R. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2012.12.010 · Cited by 243 · see citing works

Steroids, neuroactive steroids and neurosteroids in psychopathology

Dubrovsky, B. O. (2005) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.11.001 · Cited by 250 · see citing works

Adolescence: booze, brains, and behavior

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A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect

Liu, X., Chan, C.-B., Jang, S.-W., Pradoldej, S., Huang, J., He, K., Phun, L. H., France, S., Xiao, G., Jia, Y., et al. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm101206p · Cited by 208 · see citing works

Cognitive disorders and neurogenesis deficits in Huntington’s disease mice are rescued by fluoxetine

Grote, H. E., Bull, N. D., Howard, M. L., Van Dellen, A., Blakemore, C., Bartlett, P. F., & Hannan, A. J. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04365.x · Cited by 179 · see citing works

BDNF Val66Met impairs fluoxetine-induced enhancement of adult hippocampus plasticity

Bath, K. G., Jing, D. Q., Dincheva, I., Neeb, C. C., Pattwell, S. S., Chao, M. V., Lee, F. S., & Ninan, I. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.318 · Cited by 169 · see citing works

Psychedelics and Other Psychoplastogens for Treating Mental Illness.

Vargas, M. V., Meyer, R., Avanes, A. A., Rus, M., & Olson, D. E. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.727117 · Cited by 166 · see citing works

Identification of genes co‐upregulated with <i>Arc</i> during BDNF‐induced long‐term potentiation in adult rat dentate gyrus <i>in vivo</i>

Wibrand, K., Messaoudi, E., Håvik, B., Steenslid, V., Løvlie, R., Steen, V. M., & Bramham, C. R. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04687.x · Cited by 153 · see citing works

Advances in small molecules promoting neurotrophic function

PRICE, R., MILNE, S., SHARKEY, J., & MATSUOKA, N. (2007) · Pharmacology &amp; Therapeutics · doi:10.1016/j.pharmthera.2007.03.005 · Cited by 148 · see citing works

Enhanced BDNF signaling is associated with an antidepressant-like behavioral response and changes in brain monoamines

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Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants.

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Bisphenol A interferes with synaptic remodeling

Hajszan, T., & Leranth, C. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.06.004 · Cited by 101 · see citing works

Deoxygedunin, a Natural Product with Potent Neurotrophic Activity in Mice

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Changes in miRNA-132 and miR-124 levels in non-treated and citalopram-treated patients with depression

Fang, Y., Qiu, Q., Zhang, S., Sun, L., Li, G., Xiao, S., & Li, X. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.11.090 · Cited by 90 · see citing works

The Mechanisms Behind Rapid Antidepressant Effects of Ketamine: A Systematic Review With a Focus on Molecular Neuroplasticity

Kang, M. J. Y., Hawken, E., & Vazquez, G. H. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.860882 · Cited by 77 · see citing works

Imipramine Induces Brain-Derived Neurotrophic Factor mRNA Expression in Cultured Astrocytes

Takano, K., Yamasaki, H., Kawabe, K., Moriyama, M., & Nakamura, Y. (2012) · Journal of Pharmacological Sciences · doi:10.1254/jphs.12039fp · Cited by 70 · see citing works

Control of synaptic consolidation in the dentate gyrus: mechanisms, functions, and therapeutic implications

Bramham, C. R. (2007) · Progress in Brain Research · doi:10.1016/s0079-6123(07)63025-8 · Cited by 69 · see citing works

Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2

Fred, S. M., Laukkanen, L., Brunello, C. A., Vesa, L., Göös, H., Cardon, I., Moliner, R., Maritzen, T., Varjosalo, M., Casarotto, P. C., et al. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.008837 · Cited by 52 · see citing works

Antidepressant-like behavioral effects of IGF-I produced by enhanced serotonin transmission

Hoshaw, B. A., Hill, T. I., Crowley, J. J., Malberg, J. E., Khawaja, X., Rosenzweig-Lipson, S., Schechter, L. E., & Lucki, I. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.07.023 · Cited by 60 · see citing works

Analysis of antidepressant-like effects and action mechanisms of GSB-106, a small molecule, affecting the TrkB signaling

Vakhitova, Y. V., Kalinina, T. S., Zainullina, L. F., Lusta, A. Y., Volkova, A. V., Kudryashov, N. V., Gudasheva, T. A., Shimshirt, A. A., Kadnikov, I. A., Voronin, M. V., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413381 · Cited by 21 · see citing works

The Impact of BDNF, NTRK2, NGFR, CREB1, GSK3B, AKT, MAPK1, MTOR, PTEN, ARC, and SYN1 Genetic Polymorphisms in Antidepressant Treatment Response Phenotypes

Santos, M., Lima, L., Carvalho, S., Mota-Pereira, J., Pimentel, P., Maia, D., Correia, D., Barroso, M. F., Gomes, S., Cruz, A., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076758 · Cited by 20 · see citing works