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B6 vitamers as generators and scavengers of reactive oxygen species

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FOXO3a-ROS pathway is involved in androgen-induced proliferation of prostate cancer cell

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Doppler Optical Coherence Tomography

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Bau und Funktion des Süßwasserschwamms Ephydatia fluviatilis (Porifera)

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Non-Neural Reflexes: Sponges and the Origins of Behaviour

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Redox regulation of macrophage migration inhibitory factor expression in rat neurons

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Reversal of stress fibre formation by Nitric Oxide mediated RhoA inhibition leads to reduction in the height of preformed thrombi

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Small-molecule Akt-activation in airway cells induces NO production and reduces IL-8 transcription through Nrf-2

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The catch state of mollusc catch muscle is established during activation:experiments on skinned fibre preparations of the anterior byssus retractor muscle of Mytilus edulis L. using the myosin inhibitors orthovanadate and blebbistatin

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Molecular machineries of ciliogenesis, cell survival, and vasculogenesis are differentially expressed during regeneration in explants of the demosponge Halichondria panicea

Riesgo, A., Santodomingo, N., Koutsouveli, V., Kumala, L., Leger, M. M., Leys, S. P., & Funch, P. (2022) · BMC Genomics · doi:10.1186/s12864-022-09035-0 · Cited by 14 · see citing works

FOXO1 Couples KGF and PI-3K/AKT Signaling to NKX2.1-Regulated Differentiation of Alveolar Epithelial Cells

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A review of the L-arginine - nitric oxide - guanylate cyclase pathway as a mediator of lower urinary tract physiology and symptoms.

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Presence of constitutive endothelial nitric oxide synthase immunoreactivity in urothelial cells of hamster proximal urethra

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Alterations to the broad-spectrum formin inhibitor SMIFH2 modulate potency but not specificity

Orman, M., Landis, M., Oza, A., Nambiar, D., Gjeci, J., Song, K., Huang, V., Klestzick, A., Hachicho, C., Liu, S. Q., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-17685-z · Cited by 10 · see citing works

Purification and Characterization of a Novel Extracellular Tripeptidyl Peptidase from Rhizopus oligosporus

Lin, J.-S., Lee, S.-K., Chen, Y., Lin, W., & Kao, C. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf201879e · Cited by 9 · see citing works

Optical Coherence Tomography

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Small chemical compounds Y16 and Rhosin can inhibit calcium sensitization pathway in vascular smooth muscle cells of spontaneously hypertensive rats

Chiu, W.-C., Chiang, J., & Chiang, F. (2021) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2021.03.031 · Cited by 8 · see citing works

Nudibranch predation boosts sponge silicon cycling

López‐Acosta, M., Potel, C., Gallinari, M., Pérez, F. F., & Leynaert, A. (2023) · Scientific Reports · doi:10.1038/s41598-023-27411-y · Cited by 7 · see citing works

Analysis of Progranulin-Mediated Akt and MAPK Activation

Xu, S., Buraschi, S., Tanimoto, R., Stefanello, M., Belfiore, A., Iozzo, R. V., & Morrione, A. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-8559-3_9 · Cited by 7 · see citing works

Cell contractility in early animal evolution

Brunet, T. (2023) · Current Biology · doi:10.1016/j.cub.2023.07.054 · Cited by 20 · see citing works

A morphological cell atlas of the freshwater sponge Ephydatia muelleri with key insights from targeted single-cell transcriptomes

Leys, S. P., Grombacher, L., Field, D., Elliott, G. R. D., Ho, V., KAHN, A. S., Reid, P. J., Riesgo, A., Lanna, E., Bobkov, Y. V., et al. (2025) · EvoDevo · doi:10.1186/s13227-025-00237-7 · Cited by 12 · see citing works

Dynamics, diversity, and roles of bacterial transmission modes during the first asexual life stages of the freshwater sponge Spongilla lacustris

Paix, B., van der Valk, E., & de Voogd, N. J. (2024) · Environmental Microbiome · doi:10.1186/s40793-024-00580-7 · Cited by 10 · see citing works

Eating and Cognition in Two Animals without Neurons: Sponges and Trichoplax

Bechtel, W., & Bich, L. (2024) · Biological Theory · doi:10.1007/s13752-024-00464-6 · Cited by 8 · see citing works

Chemical cognition: chemoconnectomics and convergent evolution of integrative systems in animals

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Particle loads, contractile responses and cleaning in the demosponge Halichondria panicea

Goldstein, J., Riisgård, H. U., Kealy, R. A., & Funch, P. (2024) · Journal of Experimental Marine Biology and Ecology · doi:10.1016/j.jembe.2024.152021 · Cited by 5 · see citing works

ATP and glutamate coordinate contractions in the freshwater sponge Ephydatia muelleri

Ho, V., Goss, G. G., & Leys, S. P. (2025) · Journal of Experimental Biology · doi:10.1242/jeb.248010 · Cited by 5 · see citing works

Asexual Reproduction in Sponges: A Review

Ereskovsky, A. V., & Lavrov, A. (2026) · Molecular Reproduction and Development · doi:10.1002/mrd.70083 · Cited by 4 · see citing works

Novel imaging and biophysical approaches to study tissue hydraulics in mammalian folliculogenesis

Turley, J., Leong, K. W., & Chan, C. J. (2024) · Biophysical Reviews · doi:10.1007/s12551-024-01231-4 · Cited by 4 · see citing works

Microtubule organization and tubulin post-translational modifications in intact tissues and during regeneration in calcareous sponges

Skorentseva, K. V., Bolshakov, F. V., Saidova, A. A., & Lavrov, A. (2025) · Cell and Tissue Research · doi:10.1007/s00441-025-03960-8 · Cited by 3 · see citing works

Adaptive Cellular Radiations and the Genetic Mechanisms Underlying Animal Nervous System Diversification

Hehmeyer, J., Plessier, F., & Marlow, H. Q. (2024) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-111822-124041 · Cited by 3 · see citing works

How gemmules become sponges: known facts and open questions

Sokolova, A. M., & Ereskovsky, A. V. (2025) · Invertzool · doi:10.15298/invertzool.22.3.01 · Cited by 2 · see citing works

An ancient monoaminergic signaling system coordinates contractility in a nerveless spongePreprint

Zang, R. X., Malaiwong, N., Wang, L., Maziarz, J. D., Jia, K., Drotleff, B., Stein, F., Noor, M., Roberts, C. J., Rettel, M., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.14.704838 · Cited by 2 · see citing works

Growth, Filtration and Respiration Under Superfluous Feeding in Single-Osculum Halichondria panicea Sponges

Kumala, L., & Riisgård, H. U. (2024) · Oceans · doi:10.3390/oceans5040055 · Cited by 1 · see citing works

Manzamine-A: Unraveling the Chemical and Biological Tapestry of a Marine-Derived Drug Lead

Wang, X., Wang, H., Kang, Y., Tang, X., & Ma, L. (2026) · Marine Drugs · doi:10.3390/md24060190 · Cited by 1 · see citing works

Animal granulins: In the GRN scheme of things

Bowhay, C., & Hanington, P. C. (2023) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2023.105115 · Cited by 1 · see citing works

Long-term observations of a sponge in situ reveal a rich repertoire of contractile behaviors, including winter dormancy

Harrison, D., Diluvio, M., Matveev, E., Corrêa, P., Leo, F. D., & Leys, S. P. (2024) · Marine Ecology Progress Series · doi:10.3354/meps14694

Characterization of an NO-Activated Homodimeric Soluble Guanylate Cyclase from a Choanoflagellate

Wu, Y., Thomas, W. C., Green, Z. B., & Marletta, M. A. (2025) · Biochemistry · doi:10.1021/acs.biochem.5c00228

Diurnal rhythms with sunrise-induced oscular contractions suggest photosensitivity in the demosponge Halichondria paniceaPreprint

Goldstein, J., Flensburg, S. B., Garm, A. L., & Funch, P. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.23.677974

Alternative integrative systems in nerveless animals: Chemoconnectomics before synapses

Moroz, L. L. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-27380-3.00076-2

A mobile optical coherence microscope for studying aquatic organisms in- and outside the laboratoryPreprint

Wang, L., Davis, S., Quilitz, T., Beavis, T., Bonadonna, M., Lamprousi, M., Montanari, R., Ruperti, F., Stokkermans, A., Wiegand, T., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.27.740915

Oxygen regulation in the earliest animals: spatiotemporal resolution of oxygen dynamics in single-osculum Halichondria panicea and Haliclona rosea sponges

Kumala, L., Thomsen, M., & Canfield, D. E. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1849630

Learning from tandem mass spectra at scale with a self-supervised foundation model for proteomicsPreprint

Nieuwoudt, M., Reverenna, M., Patel, D., Catzel, R., Houngue, I. H. J., Daniel, J., Eloff, K., Santos, A., Carranza, N. L., Jenkins, T. P., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.03.747733

Coordinated contractions effectively expel water from the aquiferous system of a freshwater sponge

Elliott, G. R. D., & Leys, S. P. (2007) · Journal of Experimental Biology · doi:10.1242/jeb.003392 · Cited by 189 · see citing works

The reaction of the sponge Chondrosia reniformis to mechanical stimulation is mediated by the outer epithelium and the release of stiffening factor(s)

Fassini, D., Parma, L., Lembo, F., Carnevali, C., Wilkie, I. C., & Bonasoro, F. (2014) · Zoology · doi:10.1016/j.zool.2014.03.003 · Cited by 19 · see citing works

MRTF specifies a muscle-like contractile module in Porifera

Colgren, J. J., & Nichols, S. (2022) · Nature Communications · doi:10.1038/s41467-022-31756-9 · Cited by 47 · see citing works

COORDINATED PHENOMENA IN THE MARINE DEMOSPONGE CHONDROSIA RENIFORMIS: PHYSIOLOGICAL, MORPHOLOGICAL, BIOMECHANICAL AND BIOCHEMICAL ASPECTS.

Fassini, D. (2014) · Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · doi:10.13130/fassini-dario_phd2014-01-30

A muscle-related contractile tissue specified by myocardin-related transcription factor activity in PoriferaPreprint

Colgren, J., & Nichols, S. A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.11.439235 · Cited by 3 · see citing works