Numb Controls Integrin Endocytosis for Directional Cell Migration with aPKC and PAR-3

Cell Migration: Integrating Signals from Front to Back

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Adhesion assembly, disassembly and turnover in migrating cells – over and over and over again

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Clathrin-mediated endocytosis in AP-2–depleted cells

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Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase

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Calpain-mediated proteolysis of talin regulates adhesion dynamics

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Dare to Be Different: Asymmetric Cell Division in Drosophila, C. elegans and Vertebrates

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Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains: A structural prototype for diversity in integrin signaling

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The Phosphotyrosine Binding-like Domain of Talin Activates Integrins

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The Endocytic Protein α-Adaptin Is Required for Numb-Mediated Asymmetric Cell Division in Drosophila

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PDGF-regulated rab4-dependent recycling of αvβ3 integrin from early endosomes is necessary for cell adhesion and spreading

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Parsing the Polarity Code

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Stimulation‐Dependent Recycling of Integrin β1 Regulated by ARF6 and Rab11

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Numb Is an Endocytic Protein

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Binding specificity and in vivo targets of the EH domain, a novel protein–protein interaction module

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Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis

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Disabled‐2 exhibits the properties of a cargo‐selective endocytic clathrin adaptor

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Untitled work

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Endocytic recycling pathways: emerging regulators of cell migration

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CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth

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Cargo recognition during clathrin-mediated endocytosis: a team effort

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aPKC‐mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

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Asymmetric cell division

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Disabled‐2 Colocalizes with the LDLR in Clathrin‐Coated Pits and Interacts with AP‐2

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Microtubules meet substrate adhesions to arrange cell polarity

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Protrudin Induces Neurite Formation by Directional Membrane Trafficking

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Characterization of Four Mammalian Numb Protein Isoforms

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Integrin traffic

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PKD1/PKCμ promotes αvβ3 integrin recycling and delivery to nascent focal adhesions

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Real-time analysis of clathrin-mediated endocytosis during cell migration

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Recycling of the Cell Adhesion Molecule L1 in Axonal Growth Cones

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Phosphorylation of ACAP1 by Akt Regulates the Stimulation-Dependent Recycling of Integrin β1 to Control Cell Migration

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Dynamics of Endocytic Vesicle Creation

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Membrane traffic during cell locomotion

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Modes of Protein Movement that Lead to the Asymmetric Localization of Partner of Numb during Drosophila Neuroblast Division

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Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion

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Phosphorylation of Numb Family Proteins

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Decreased polarity and increased random motility in PtK1 epithelial cells correlate with inhibition of endosomal recycling

Prigozhina, N. L., & Waterman, C. M. (2006) · Journal of Cell Science · doi:10.1242/jcs.03066 · Cited by 33

A Novel Adapter Protein Employs a Phosphotyrosine Binding Domain and Exceptionally Basic N-terminal Domains to Capture and Localize an Atypical Protein Kinase C

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Mechanisms of endocytosis

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Random versus directionally persistent cell migration

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The PAR Proteins: Fundamental Players in Animal Cell Polarization

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Derailed endocytosis: an emerging feature of cancer

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Tickets to ride: selecting cargo for clathrin-regulated internalization

Traub, L. M. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2751 · Cited by 565