The DOI matches its Crossref record; 146 of the 146 references it cites were found in a registry or an index.
Mechanisms of Cardiac Regeneration
Open accessAbstract
Adult humans fail to regenerate their hearts following injury, and this failure to regenerate myocardium is a leading cause of heart failure and death worldwide. Although all adult mammals appear to lack significant cardiac regeneration potential, some vertebrates can regenerate myocardium throughout life. In addition, new studies indicate that mammals have cardiac regeneration potential during development and very soon after birth. The mechanisms of heart regeneration among model organisms, including neonatal mice, appear remarkably similar. Orchestrated waves of inflammation, matrix deposition and remodeling, and cardiomyocyte proliferation are commonly seen in heart regeneration models. Understanding why adult mammals develop extensive scarring instead of regeneration is a crucial goal for regenerative biology.
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Cites
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Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration
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Heart Regeneration in Zebrafish
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Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system
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Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
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Cited by
Mitochondria and ageing: Role in heart, skeletal muscle and adipose tissue
Boengler, K., Kosiol, M., Mayr, M., Schulz, R., & Rohrbach, S. (2017) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12178 · Cited by 421
The Macrophage in Cardiac Homeostasis and Disease
Lavine, K. J., Pinto, A. R., Epelman, S., Kopecky, B. J., Clemente-Casares, X., Godwin, J., Rosenthal, N., & Kovacic, J. C. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.08.2149 · Cited by 234
The Role of the Epicardium During Heart Development and Repair
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Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration
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Cardiac Fibroblasts and the Extracellular Matrix in Regenerative and Nonregenerative Hearts
Hortells, L., Johansen, A. K. Z., & Yutzey, K. E. (2019) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd6030029 · Cited by 79
Metadata
- Authors
- Uygur, A., & Lee, R. T.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2016-02
- Volume
- 36
- Issue
- 4
- Pages
- 362-374
- ISSN
- 1534-5807 (ISSN-L)
- OpenAlex
- W2279233812
- Cited by
- 286
- References
- 146
- FWCI
- 15.35
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
