The DOI matches its Crossref record; 97 of the 100 references it cites were found in a registry or an index.
Impact of visceral adipose tissue on liver metabolism
Abstract
Excess visceral adipose tissue is associated with anomalies of blood glucose homoeostasis, elevation of plasma triglycerides and low high-density lipoprotein cholesterol that contribute to the later appearance of type 2 diabetes and cardiovascular syndromes. Visceral adipose tissue releases a large amount of free fatty acids and hormones/cytokines in the portal vein that are delivered to the liver, and interact with hepatocytes and various immune cells in the liver. The functional characteristics of visceral adipose tissue will be compared with subcutaneous adipose tissue to clarify the major mechanisms affecting free fatty acid metabolism and cytokine production.
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“This led to increased lifespan in model organisms and in animal models (280,281) .”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [281]
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Retraction Note: Effects of DA-5513 on alcohol metabolism and alcoholic fatty liver in rats
Yu, J. Y., Nguyen, H. T., Yong, C. S., Park, H. G., Jun, J. H., & Kim, J. O. (2020) · Laboratory Animal Research · doi:10.1186/s42826-020-00047-z
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Mo, L., Zhao, C., Wang, T., Xu, W., Deng, Y., Yu, Y., & Zeng, X. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1960914
“Due to the anatomical proximity and vascular linkage via the portal vein, the liver acts as a major metabolic organ responsible for processing adipose-derived FFAs and gut-derived nutrients (34).”
Redundant Human Omentum Fat: A Leap Towards Regenerative Medicine
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Metadata
- Authors
- Lafontan, M., & Girard, J.
- Affiliations
- Université Toulouse III - Paul Sabatier (FR)
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Lafontan, M.
- Venue
- Diabetes & Metabolism
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 34
- Issue
- 4
- Pages
- 317-327
- ISSN
- 1262-3636 (ISSN-L)
- OpenAlex
- W1980825557
- Cited by
- 143
- References
- 100
- Citations by year
- 2026: 6 · 2025: 3 · 2024: 2 · 2023: 5 · 2022: 5 · 2021: 4 · 2020: 7 · 2019: 8 · 2018: 8 · 2017: 7 · 2016: 6 · 2015: 11 · 2014: 9 · 2013: 13 · 2012: 12
- FWCI
- 1.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetes & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
- Keywords
- visceral adipose tissue, hepatic metabolism, free fatty acid metabolism, cytokines, adipokines, portal vein, subcutaneous adipose tissue, glucose homeostasis, hypertriglyceridemia, low HDL cholesterol, type 2 diabetes, cardiovascular risk, hepatocytes
- MeSH terms
- Diabetes Mellitus, Type 2, Fatty Acids, Nonesterified, Female, Humans, Insulin Resistance, Liver, Male, Obesity, Adipocytes, Glucose Intolerance, Intra-Abdominal Fat, Abdominal Fat, Subcutaneous Fat, Abdominal, Adipokines
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