Nicotine Dependence and Psychiatric and Substance Use Disorder Comorbidities among American Indians/Alaska Natives: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions
Abstract
Background American Indians and Alaska Natives (AI/ANs) have high rates of tobacco use compared to the general population. AI/ANs also have elevated rates of psychiatric and substance use disorders associated with nicotine dependence. However, very few studies have examined the comorbidity between nicotine dependence and psychiatric and substance use disorders within this population. Methods This study analyzes the comorbidity of lifetime nicotine dependence with both current and lifetime psychiatric disorders and substance use disorders in a nationally representative sample of 701 AI/AN women and men. Results Using 95% confidence interval testing, lifetime nicotine dependence (29.5%) was associated with all main diagnostic categories (any mood disorder, any anxiety disorder, any personality disorder, any alcohol use disorder, and any drug use disorder) both at the lifetime level and current (12-month) level. Of the lifetime disorders, the strongest associations were with psychosis and drug dependence. For (current) 12-month disorders, the strongest associations were with alcohol dependence and drug dependence. Differences were noted between genders regarding personality disorders. Conclusions Culturally appropriate tobacco screening, prevention, and treatment curricula for adult AI/ANs with dual diagnoses are recommended. Understanding historically based factors that may contribute to psychiatric illness and substance use disorders may assist in more effective nicotine treat…
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Limited experimental and longitudinal research makes it difficult to assert whether polysubstance use is an outcome of substance use addictions or a risk factor for such addictions, although there is some support for the latter.
“Limited experimental and longitudinal research makes it difficult to assert whether polysubstance use is an outcome of substance use addictions or if polysubstance use is a risk factor for such addictions (or both), although there is some support for the latter [50,56,57].”
From Substance and Behavioral Addictions among American Indian and Alaska Native Populations (2022) · cites this paper as [50]
Strong relationships were found between past-year use of alcohol and drug dependence.
“Strong relationships were found between past-year use of alcohol and drug dependence [50].”
From Substance and Behavioral Addictions among American Indian and Alaska Native Populations (2022) · cites this paper as [50]
Risk factors often have synergistic and cumulative effects on SUD.
“As can be inferred, risk factors often have synergistic and cumulative effects on SUD [50].”
From Substance and Behavioral Addictions among American Indian and Alaska Native Populations (2022) · cites this paper as [50]
Lifetime and past-year nicotine dependence were correlated with mood, anxiety, and personality disorders, alcohol use, and any drug use disorders in a nationally representative sample of AIAN adults.
“Lifetime and past-year nicotine dependence were correlated with mood, anxiety, and personality disorders, alcohol use, and any drug use disorders [50].”
From Substance and Behavioral Addictions among American Indian and Alaska Native Populations (2022) · cites this paper as [50]
Psychosis, personality, and other mood disorders (e.g., posttraumatic stress disorder) are intricately linked with substance use and dependence among AIANs.
“Psychosis, personality, and other mood disorders (e.g., posttraumatic stress disorder) are intricately linked with substance use and dependence as well [49,50,51].”
From Substance and Behavioral Addictions among American Indian and Alaska Native Populations (2022) · cites this paper as [50]
Poverty, acculturation, and personality disorders appear to be risk factors for addiction in AIAN individuals as well.
“Consistent with prior research in non-AIAN samples, poverty, acculturation, and personality disorders [95,96,97,98] appear to be risk factors for addiction in AIAN individuals as well [33,43,50].”
From Substance and Behavioral Addictions among American Indian and Alaska Native Populations (2022) · cites this paper as [50]
Cites
Petry, N. M., Stinson, F. S., & Grant, B. F. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0504 · Cited by 1,245 · cited 1× · see citing works
“In the generalpopulation, the rate of omorbidity between pathological gambling and nicotine dependnce has been cited as high as 60% (Petry et al., 2005), and in our revious study, the comorbidity rate was 17%, with pathological ambling being significantly associated with nicotine dependence Dickerson et al.”
BackgroundExtent of smoking and nicotine dependence in the United States: 19911993
Chen, D. B. K. (2000) · Nicotine & Tobacco Research · doi:10.1080/14622200050147538 · Cited by 261 · see citing works
Whitesell, N. R., Beals, J., Crow, C. B., Mitchell, C. M., & Novins, D. K. (2012) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952990.2012.694527 · Cited by 196 · see citing works
Anstey, K. J., von Sanden, C., Sargent-Cox, K., & Luszcz, M. A. (2007) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31802e21d8 · Cited by 192 · see citing works
Mental Disorders and Cigarette Use among Adults in the United States
Goodwin, R. D., Zvolensky, M. J., Keyes, K. M., & Hasin, D. S. (2012) · The American Journal on Addictions · doi:10.1111/j.1521-0391.2012.00263.x · Cited by 64 · see citing works
Dickerson, D. L., O’Malley, S. S., Canive, J., Thuras, P., & Westermeyer, J. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.07.014 · Cited by 34 · see citing works
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Substance and Behavioral Addictions among American Indian and Alaska Native Populations
Soto, C., West, A. E., Ramos, G. G., & Unger, J. B. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19052974 · Cited by 49 · see citing works
“Strong relationships were found between past-year use of alcohol and drug dependence [50].”
BackgroundResultInfluential
- Authors
- Moghaddam, J. F., Dickerson, D. L., Yoon, G., & Westermeyer, J.
- Affiliations
- University of California, Los Angeles (US)
- University of Minnesota (US)
- Corresponding author
- Moghaddam, Jacquelene F.
- Venue
- Drug and Alcohol Dependence
- Publisher
- Elsevier BV
- Published
- 2014-11
- Volume
- 144
- Pages
- 127-133
- ISSN
- 0376-8716 (ISSN-L)
- OpenAlex
- W2008682559
- Cited by
- 20
- References
- 6
- Citations by year
- 2025: 3 · 2023: 4 · 2022: 1 · 2021: 1 · 2020: 4 · 2019: 2 · 2018: 2 · 2016: 2 · 2015: 1
- FWCI
- 0.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Drug and Alcohol Dependence (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Health › Indigenous Health, Education, and Rights
- Keywords
- nicotine dependence, American Indians and Alaska Natives, psychiatric comorbidity, substance use disorders, dual diagnosis, tobacco use, mood disorders, anxiety disorders, personality disorders, alcoholism, drug use disorders, psychosis, gender differences, tobacco use screening, culturally appropriate treatment
- MeSH terms
- Adolescent, Adult, Alaska, Anxiety Disorders, Mental Disorders, Female, Health Surveys, Humans, Indians, North American, Male, Middle Aged, Tobacco Use Disorder, Comorbidity, Diagnosis, Dual (Psychiatry), Mood Disorders, Substance-Related Disorders, Alcohol-Related Disorders, Drug Users
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