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Cited by 36Substance Abuse Treatment and OutcomesCannabis and Cannabinoid ResearchGambling Behavior and Treatments

Comorbidity and temporal relations of alcohol and cannabis use disorders from youth through adulthood

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Duncan, Susan C., Gau, Jeff M., Farmer, Richard F., Seeley, John R., Kosty, Derek B., Lewinsohn, Peter M.·2015·Drug and Alcohol Dependence
DOI 10.1016/j.drugalcdep.2015.01.025PMC PMC4361280
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Abstract

Background Alcohol and cannabis are among the most widely used and abused drugs in industrialized societies. Investigations of patterns in comorbidity and temporal sequencing between alcohol use disorders (AUDs) and cannabis use disorders (CUDs) from childhood to adulthood are important for understanding the etiologies of these disorders. Methods The sample comprised 816 individuals (59% male, 89% white). Dichotomous measures indicated whether or not a participant was in an AUD or CUD episode during three developmental periods-youth (childhood through adolescence), early adulthood, and adulthood. Structural equation modeling was used to determine relations between AUDs and CUDs across the three developmental periods, and to test for gender differences. Results Concurrent associations between AUD and CUD were significant. Both AUD and CUD in previous developmental periods significantly predicted the same substance disorders in subsequent periods. Cross-lagged paths from youth AUD to young adult CUD and youth CUD to young adult AUD were both significant. However, only the cross-lagged path from youth CUD to adult AUD was significant. The cross-lagged paths from young adult AUD to adult CUD and young adult CUD to adult AUD were both nonsignificant. Males and females were mostly similar with only three differences found between genders. Conclusions Comorbidity of AUDs and CUDs was evident from youth through adulthood but the strength of the relationship lessened in adulthood. Temporal sequencing influences of AUDs and CUDs on each other were similar in youth and adulthood but not young adulthood. Same substance stability was greatest in adulthood.

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Cited by

Sorted by citations

Authors
Duncan, S. C., Gau, J. M., Farmer, R. F., Seeley, J. R., Kosty, D. B., & Lewinsohn, P. M.
Affiliations
Oregon Research Institute (US)
Corresponding author
Duncan, Susan C.
ORCID
Venue
Drug and Alcohol Dependence
Publisher
Elsevier BV
Published
2015-04
Volume
149
Pages
80-86
ISSN
0376-8716 (ISSN-L)
DOI
10.1016/j.drugalcdep.2015.01.025
PMC
PMC4361280
OpenAlex
W2004544623
Cited by
36
References
7
Citations by year
2026: 2 · 2025: 3 · 2024: 1 · 2023: 4 · 2021: 5 · 2020: 5 · 2019: 5 · 2018: 3 · 2017: 3 · 2016: 4
FWCI
2.62
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Drug and Alcohol Dependence (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute on Alcohol Abuse and Alcoholism (R01AA020968)
  • National Institute of Mental Health (R01MH040501, R01MH050522)
  • National Institute on Drug Abuse (R01DA012951, R01DA032659, DA12951)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
  • Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
Keywords
alcoholism, cannabis use disorder, substance use comorbidity, developmental trajectories, adolescent substance use, early adulthood, adulthood, gender differences
MeSH terms
Adolescent, Adult, Aging, Alcoholism, Marijuana Abuse, Data Interpretation, Statistical, Female, Humans, Male, Oregon, Psychiatric Status Rating Scales, Rural Population, Sex Characteristics, Urban Population, Models, Statistical, Young Adult

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